Handbook of Nonmedical Applications of Liposomes
First published in 1996, liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. In these volumes many of the top experts contribute extensive reviews of their work.
Biomedical Application of Nanoparticles
This book explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune systems and targeted cells. Risk assessment of nanoparticles for human use is described, including: cellular paradigms, transcriptomics and toxicogenomics.
Biology of Perch
The genus Perca includes only three species of fish, but they are ubiquitous and abundant in freshwater and brackish environments of the northern hemisphere, from North America to Europe and Asia. These species are important both ecologically and economically. In Biology of Perch, world-renowned specialists review and update the bi
Handbook of Nonmedical Applications of Liposomes
First published in 1996, liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. In these volumes many of the top experts contribute extensive reviews of their work.
Was ist die Ursache der ”Neuartigen Waldsch瓣den” bei Laubb瓣umen?
Forschungsarbeit aus dem Jahr 2018 im Fachbereich Forstwirtschaft / Forstwissenschaft, Sprache: Deutsch, Abstract: In der Arbeit wird die These vertreten, dass die jetzigen "Neuartigen Waldsch瓣den" der Laubb瓣ume prim瓣r durch pflanzenexterne Radikale bedingt sind. Externe Radikale entstammen vor allem den in Deutschland seit den 1950er Jahren st瓣ndig gestiegenen Emissionen aus dem Kfz- und Flugverkehr. Insgesamt kommt es dadurch zu einer vorgezogenen physiologischen Alterung der Laubb瓣ume. Ein besonderer Schwerpunkt liegt dabei auf den Sch瓣den, welche f羹r Buche und Eiche entstehen. Die Arbeit bezieht sich auf die in Deutschland heimischen Buchen und Eichen; ihre Ergebnisse sind auf alle Laubbaumarten 羹bertragbar. Fr羹h traten die Laubbaumsch瓣den bei solit瓣ren B瓣umen im freien Feld auf, an Brennpunkten des Verkehrs wie um den Flughafen Frankfurt a. M. mit seinen hochfrequentierten Autobahnen und um Stuttgart. Die Ursache der "Neuartigen Waldsch瓣den" wird in pflanzenexternen Radikalen gesehen. Um die Sch瓣den der Laubb瓣ume, des gesamten Wald繹kosystems zu mindern, sind politische Ma?nahmen wie technische Weiterentwicklungen unabdingbar.
Pigmentbestimmung von phototrophen Mikroorganismen. Einfluss verschiedener Zellaufschlussmethoden und Extraktionsparameter
Bachelorarbeit aus dem Jahr 2014 im Fachbereich Biologie - Mikrobiologie, Molekularbiologie, Note: 1,0, Friedrich-Alexander-Universit瓣t Erlangen-N羹rnberg, Sprache: Deutsch, Abstract: Vor dem Hintergrund einer qualitativen und quantitativen Bestimmung der Pigmente Astaxantin (Ast.), Lutein (Lut.) und β-Carotin (Car.) f羹r ausgew瓣hlte phototrophe Mikroorganismen sind verschiedene Zellaufschlussmethoden sowie Extraktionsparameter hinsichtlich deren Eignung untersucht worden. Betrachtet wurden dabei unterschiedliche mechanische und physikalische Methoden. Bei den pigmentbildenden Mikroalgen handelt es sich um Haem. pluvialis, Chr. zofingiensis und Chl. sorokiniana. Diese wurden mittels Tissue Lyser, Ultra Turrax, French Press, Lyophilisierung, Ultraschallhomogenisierung und wiederholtes Einfrieren und Auftauen aufgeschlossen, anschlie?end extrahiert und auf ihren Pigmentgehalt untersucht. Weiterhin fand im Rahmen dieser Arbeit ein L繹sungsmittel-screening f羹r die Extraktion der aufgeschlossenen Biomasse mittels accelerated solvent extraction (ASE) statt. Hierzu wurden nach vorausgehender Literaturrecherche Aceton, Dichlormethan, Ethylacetat, n-Hexan, Ethanol und Dimethylsulfoxid als geeignete L繹sungsmittel ausgew瓣hlt. Weiterhin wurde die etablierte Standardmethode mit einer L繹sungsmittelmischung aus Aceton und Methanol im Verh瓣ltnis 9 zu 1 (v/v) als Referenzextraktion verwendet. Hierbei sind identische, aufgeschlossene Proben von Haem. pluvialis extrahiert und anschlie?end miteinander verglichen worden.
Plant Performance. Die Auswirkungen einer pflanzlichen Ern瓣hrung auf das physische Selbstkonzept und die Leistungsf瓣higkeit von Kraftsportlern
Wie leistungsf瓣hig bin ich? Und kann ich meine Leistungsf瓣higkeit beeinflussen? Fragen, die vielen Sportlern im Verlaufe ihrer Karriere begegnen. Um sie beantworten zu k繹nnen, bedarf es einer Auseinandersetzung mit dem Selbst. Das sogenannte physische Selbstkonzept fasst selbstrelevante Informationen mit eigenem K繹rperbezug zusammen und bewertet diese. "Ich habe gro?e Muskeln, also f羹hle ich mich hinsichtlich meiner Kraftf瓣higkeit leistungsf瓣hig", scheint eine plausible Antwort. Doch so einfach lassen sich die Fragen aus dem multidimensionalen Gef羹ge des Selbstkonzepts nicht ableiten. Mit dem Ziel der optimalen Leistungsf瓣higkeit r羹ckt auch das Thema Ern瓣hrung immer mehr in den Fokus der Sportwissenschaft. Die Relevanz ist eindeutig: Der K繹rper ben繹tigt Energie, um leistungsf瓣hig zu sein. Doch nicht nur das. Durch die Auswirkungen auf physiologische Prozesse, welche die Leistungsf瓣higkeit w瓣hrend des Trainings beeinflussen, sowie fortf羹hrend der Beteiligung an Regenerationsprozessen beanspruchter Muskulatur wird eine sportartspezifische Ern瓣hrung unerl瓣sslich. Wie die Ern瓣hrung in Verbindung zum Selbstkonzept steht, sowie die Antwort auf die Frage, was der K繹rper f羹r optimalen Trainingsfortschritt im Krafttraining ben繹tigt und ob eine pflanzliche Ern瓣hrung geeignete Rahmenbedingungen daf羹r bietet, finden sie abgeleitet aus der Physiologie des Menschen und unter R羹ckbezug zur aktuellen wissenschaftlichen Datenlage in diesem Buch.
The New Eugenics
The specter of early twentieth-century eugenics-with its goal of preventing the "unfit" from reproducing through forced sterilization-still haunts us in this era of genetic engineering. Conrad B. Quintyn, an associate professor of biological anthropology at Bloomsburg University, Bloomsburg, Pennsylvania, calls this the new eugenics era because geneticists have begun to explore ways to prevent and repair defective genes in all humans. In this book, he considers whether genetic engineering will exacerbate social injustices and/or lead to a public safety issue. For instance, in 2012, virologists in the U.S. and the Netherlands genetically engineered avian (bird) flu to be more transmissible between mammals. These scientists argued that virus transmission between mammals enables us to make vaccines to prevent pandemics. They never considered what would happen if the virus accidentally escaped the laboratory. Meanwhile, some scientists are experimenting with "designer babies," altering genes to remove diseases and even programming certain traits. Join the author as he considers whether scientists are playing God as well as the risks we face by altering genetics in The New Eugenics.
Calf and Heifer Feeding and management
From birth to first calving, the replacement heifer undergoes tremendous changes anatomically as well as in feeding and management practices. The calf changes from being a pseudo-monogastric to a full ruminant within a period of two months. During the same period, the calf is fed colostrum, milk, or milk replacer, and starter with or without hay. Notably, the lifetime milk production and health of a dairy cow is highly dependent on early life nutrition and management of the calf and, subsequently, the heifer. Hence, animal scientists continue to investigate critical areas such as colostrum feeding, the level of liquid feeding, gut microbial succession, energy and protein levels, housing, health management, and their interactions with the animal in an effort to help dairy producers raise successful and sustainable dairy enterprises.
Actinobacteria and Myxobacteria
Bacterial infections cause millions of deaths globally, particularly in children and the elderly, and four of the 10 leading causes of death are infectious diseases in low- and middle-income countries. The continuous use of antibiotics has resulted in multi-resistant bacterial strains all over the world, such as Community-associated Methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamases (ESBLs), and, as expected, hospitals have become breeding grounds for human-associated microorganisms, especially in critical care units.
Autophagy in Tissue Injury and Homeostasis
Autophagy ("auto-digestion"), a lysosome-dependent process, degrades and turns over damaged or senescent organelles and proteins. Autophagy is a highly regulated process that impacts several vital cellular responses, including inflammation, cell death, energy metabolism, and homeostasis of organelles (mitochondria and others). Although the role of autophagy in the maintenance of tissue homeostasis is well documented, its role during tissue injury and regeneration is still emerging. In this Special Issue on "Autophagy in Tissue Injury and Homeostasis", we focus on the roles of autophagy in systemic, specific tissue (organs/cells) injury or organ failure associated with sepsis, inflammation, metabolic disorder, toxic chemicals, ischemia-reperfusion injury, hypoxic oxidative stress, tissue fibrosis, trauma, and nutrient starvation. The knowledge gained from the identification and characterization of new molecular mechanisms will shed light on biomedical applications for tissue protection through the modulation of autophagy.
Fashion’s Biofabrication Revolution
Have you ever imagined being able to wear a piece of clothing that was grown for you? In Ayesha Ahmad's Fashion's Biofabrication Revolution, she shares how that's not only possible, but the future of fashion.In this book, you will discover how this industry has evolved and why we're now at the crossroads between buying the next big thing and needing to make choices that will protect the environment. In this eye-opening work, you will learn: What fast fashion has done to our environment and why we need to alter our relationship with the clothing we wear.How biofabrication is changing the fashion industry and what designers and scientists have already accomplished.Why bacteria is referred to as nature's perfected tool and the incredible uses we have for it.Exploring the past, present, and future, you'll see how America's fashion industry has progressed and how biofabrication will change it for the better.
The Role of Biofilms in the Development and Dissemination of Microbial Resistance within the Food Industry
Biofilms are multicellular sessile microbial communities embedded in hydrated extracellular polymeric matrices. Their formation is common in microbial life in most environments, whereas those formed on food-processing surfaces are of considerable interest in the context of food hygiene. Biofilm cells express properties that are distinct from planktonic ones, in particular, due to their notorious resistance to antimicrobial agents. Thus, a special feature of biofilms is that once they have developed, they are hard to eradicate, even when careful sanitization procedures are regularly applied. A large amount of ongoing research has investigated how and why surface-attached microbial communities develop such resistance, and several mechanisms can be acknowledged, such as heterogeneous metabolic activity, cell adaptive responses, diffusion limitations, genetic and functional diversification, and microbial interactions. The articles contained in this Special Issue deal with biofilms of some important food-related bacteria (including common pathogens such as Salmonella enterica, Listeria monocytogenes, and Staphylococcus aureus, as well as spoilage-causing spore-forming bacilli), providing novel insights into their resistance mechanisms and implications, together with novel methods (e.g., use of protective biofilms formed by beneficial bacteria, enzymes) that could be used to overcome resistance and thus improve the safety of our food supply and protect public health.
Biological Evolution
Biological evolution, the theory of natural selection and of common descent, is a triumph both of human reasoning and scientific undertaking. The biological discipline of evolution contains both a chronicle of human endeavour and the story of life on Earth. This book is concerned with living forms and how they developed from 'simple and unpromising beginnings'. It considers evolution as both process and product. The author, an experienced teacher and educator, employs a historical narrative, used to convey the idea of 'change with modification' and to emphasise the relevance of evolution to contemporary bioscience. Biological evolution has now become part of the scientific orthodoxy and this accessible text will assist undergraduate students in the biological sciences within any ongoing debate.
Rapid Methods for Assessing Food Safety and Quality
Food safety and quality represent a major concern worldwide, not only for the potential risk to consumers' health but also for the economic losses occurring in food industries. A complete quality system involves raw matter, environmental conditions, production processes, storage and distribution, taking into account the purpose for which the end product is intended. Appropriate analytical methods combined with good hygiene practices are essential to ensure a safe food supply and/or to minimize the occurrence of foodborne outbreaks due to the consumption of food contaminated with pathogens such as bacteria, fungi and parasites. On the other hand, the lack of measures able to detect quality deterioration, spoilage, authenticity and adulteration, as well as texture, rheology and sensory properties of food can affect the food industry economy and reduce consumer confidence. The use of rapid analytical methods can benefit food companies in saving time and cost, indicating the importance of developing new reliable assays for good and fast control of products throughout the whole food chain.
Visual Learning: Biology
Barron's new Visual Learning series breaks down complex science concepts into clear, captivating illustrations for the visual learner! With large, colorful graphics, including maps, diagrams, and labeled illustrations and clear supporting text, Visual Learning: Biology is an invaluable resource for readers of all ages who want to learn science in an easy and engaging way. Learn key biology topics including: CellsGeneticsMetabolismPlant and animal structure and functionHuman health and diseaseEcologyBiology in the 21st century, and much more.
Coastal Aquaculture and Mariculture
This book is divided into 40 chapters covering introduction, mariculture scenario, seaweed farming, recirculatory aquaculture systems, conservation aspects in mariculture etcNote: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.
Killing Cancer
Despite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million by 2030. There is clearly a need for not only more research but also more innovative and out of the mainstream scientific ideas to discover and develop even better cancer treatments. This book presents the collective works published in the recent Special Issue entitled "Killing Cancer: Discovery and Selection of New Target Molecules". These articles comprise a selection of studies, ideas, and opinions that aim to facilitate knowledge, thoughts, and discussion about which biological and molecular mechanisms in cancer we should target and how we should target them.
The Foundations Of The Origin Of Species
The Foundations Of The Origin Of Species: Two Essays Written In 1842 And 1844, Edited By His Son Francis Darwin This book is a result of an effort made by us towards making a contribution to the preservation and repair of original classic literature. In an attempt to preserve, improve and recreate the original content, we have worked towards: 1. Type-setting & Reformatting: The complete work has been re-designed via professional layout, formatting and type-setting tools to re-create the same edition with rich typography, graphics, high quality images, and table elements, giving our readers the feel of holding a 'fresh and newly' reprinted and/or revised edition, as opposed to other scanned & printed (Optical Character Recognition - OCR) reproductions. 2. Correction of imperfections: As the work was re-created from the scratch, therefore, it was vetted to rectify certain conventional norms with regard to typographical mistakes, hyphenations, punctuations, blurred images, missing content/pages, and/or other related subject matters, upon our consideration. Every attempt was made to rectify the imperfections related to omitted constructs in the original edition via other references. However, a few of such imperfections which could not be rectified due to intentional\unintentional omission of content in the original edition, were inherited and preserved from the original work to maintain the authenticity and construct, relevant to the work. We believe that this work holds historical, cultural and/or intellectual importance in the literary works community, therefore despite the oddities, we accounted the work for print as a part of our continuing effort towards preservation of literary work and our contribution towards the development of the society as a whole, driven by our beliefs. We are grateful to our readers for putting their faith in us and accepting our imperfections with regard to preservation of the historical content. HAPPY READING!
Artificial Intelligence Platform for Molecular Targeted Therapy: A Translational Science Approach
In the era of big biomedical data, there are many ways in which artificial intelligence (AI) is likely to broaden the technological base of the pharmaceutical industry. Cheminformatic applications of AI involving the parsing of chemical space are already being implemented to infer compound properties and activity. By contrast, dynamic aspects of the design of drug/target interfaces have received little attention due to the inherent difficulties in dealing with physical phenomena that often do not conform to simplifying views.This book focuses precisely on dynamic drug/target interfaces and argues that the true game change in pharmaceutical discovery will come as AI is enabled to solve core problems in molecular biophysics that are intimately related to rational drug design and drug discovery.Here are a few examples to convey the flavor of our quest: How do we therapeutically impair a dysfunctional protein with unknown structure or regulation but known to be a culprit of disease? In regards to SARS-CoV-2, what is the structural impact of a dominant mutation?, how does the structure change translate into a fitness advantage?, what new therapeutic opportunity arises? How do we extend molecular dynamics simulations to realistic timescales, to capture the rare events associated with drug targeting in vivo? How do we control specificity in drug design to selectively remove side effects? This is the type of problems, directly related to the understanding of drug/target interfaces, that the book squarely addresses by leveraging a comprehensive AI-empowered approach.
Fungi for Human Health
1. Preface2. Foreword3. Introduction4. Occurrence and distribution5. Traditional uses6. Fungi as food7. Fungi in medicine(i) Antidiabetic mushrooms(ii) Mushrooms as antioxidants(iii) Mushrooms against cancer(iv) Mushrooms as antimicrobial agents(v) Anti-inflammatory effects(vi) Other medicinal uses8. Mycochemicals composition of fungi9. Conclusion10. Outlook and future perspectives
Tutorium Genetik
Genetik geht jeden an, ob man f羹r eine Pr羹fung lernt, oder einfach nur ein Lebewesen ist. Warum nicht ein wenig mehr dar羹ber wissen?Dieses Buch gibt eine gute, leicht zu lesende und stellenweise sogar witzige Einf羹hrung in die Genetik und Molekularbiologie. Von den Grundlagen ausgehend erkl瓣rt es auch komplexere Zusammenh瓣nge und konzentriert sich besonders auf die h瓣ufigsten Lern-Probleme von Studenten. Sowohl f羹r Studierende der Biologie, medizinischer Fachgebiete oder interessierte Laien bietet dieses Buch daher einen hervorragenden Einstieg. Die Leser werden bei den chemischen Grundlagen abgeholt und 羹ber die Genexpression, die Genregulation und Mendels Erbsen bis hin zu den technischen M繹glichkeiten der Genetik begleitet. Neben spannenden Exkursen bietet jedes Kapitel am Ende eine Kurzzusammenfassung, welche besonders f羹r eine Wiederholung kurz vor der Pr羹fung geeignet ist.
Metal Ions in Biochemistry
The second edition of the book "Metal Ions in Biochemistry" deals exhaustively with the role of metal and non-metal ions in biochemical reactions, and also the effect of deficiency of metal ions, toxic effects of metal ions and use of metal complexes in therapeutics.
B I O E T I C a
B I O E T I C A: SCIENZA E TECNOLOGIA AL SERVIZIO DELLA UMANIT? PRODUZIONE, CRIOCONSERVAZIONE E ADOZIONE DI EMBRIONI UMANI
Microbial Ecology
The essays that comprise this anthology of the best in ecology from critical reviews in microbiology describe principles and practices in considerable detail. The book is an interesting and informative introduction to a growing endeavour, and will aid the reader to develop an ecological attitude and better appreciate microorganisms.
Physical Basis of Cell-Cell Adhesion
The Present book is aimed at providing a readable account of physical methods and results required to measure cell adhesion and interpret experimental data.
Advancements and Innovations in Health Sciences
This book focuses on recent advances regarding clinical conditions and ailments whose mechanisms remain unclear, limiting our ability to treat them. The respective chapters address a range of multidisciplinary topics related to timely or emergent research areas, such as osteoporosis in postmenopausal women, the optimal surgical procedures for vertebral compression fractures, novel rehabilitative approaches in pelvic muscle training in case of urinary incontinence, and a rational approach to balneotherapy not only for the skin but also other organ systems disorders. Alterations in the endocrine function during strenuous physical activity at high altitude - a multi-stressor environment comprising hypobaric hypoxia, exercise, and nutritional changes - are presented as well. Other articles provide evidence-based insights into the diagnosis, mechanisms, and clinical course of respiratory infections in children such as bronchiolitis, pneumonia, and influenza. Finally, the pros andcons of e-health are discussed; a rapidly growing area based on the use of information and communication technology to streamline the flow of health information and patient-healthcare provider connections. The content is a well-structured blend of research and practical aspects, as well as updates on cutting-edge developments. All these essential topics are presented in a format suitable for medical professionals engaged in day-to-day patient care and therapy, as well as researchers, academics, and physiotherapists.
RNA Genetics
This book reviews the early evidence of genetic variability of rhabdoviruses. It describes data on the variability in the genomes of closely related virus strains and the variability that can be observed within a given virus strain.
RNA Genetics
This book describes the basic features of virus replication, and points out how these features lead into the diverse biologies and genetics of the various viruses.
The Tight Junction and Its Proteins
For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ-mainly the two families of claudins and TAMPs-several other functions have been discovered, a striking one being the surprising finding that some claudins form paracellular channels for small ions and/or water. This Special Issue includes 43 articles covering numerous dedicated topics including pathogens affecting the TJ barrier, TJ regulation via immune cells, the TJ as a therapeutic target, TJ and cell polarity, function and regulation by proteins of the tricellular TJ, TJ as a regulator of cellular processes, organ- and tissue-specific functions, TJ as sensors and reacting to environmental conditions, and last but not least, TJ proteins and cancer.
Tuberculosis Drug Discovery and Development 2019
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.
Yoga Anatomy Coloring Book for Experts
Looking for an easy, fun and effective way to demystify the anatomical structures underlying each yoga pose?Coloring the anatomy and physiology of each asana is the most effective way to study the structure and functions of yoga movements. You assimilate information and make visual associations with key terminology when coloring in the Yoga Anatomy Coloring Book for Experts, all while having fun!Whether you are a yoga instructor or just interested in discovering how the anatomy of our body responds to each body position, let this book guide you.While other books give you the anatomical terminology immediately, this book is designed for convenient self-testing by providing the answer keys on the back of the same page so you can get the most out of your studies. Plus, the detailed illustrations of the anatomical systems in a large page design without back-to-back drawings will make you say goodbye to bleed-through!The Yoga Anatomy Coloring Book for Experts features: The most effective way to skyrocket your anatomical knowledge and deepen your understanding of yoga, all while having fun!Full coverage of the major systems of the human body to provide context and reinforce visual recognition50+ unique, easy-to-color pages of different Expert yoga poses with their anatomy & terminologyLarge 8.5 by 11-inch single side paper so you can easily remove your coloringSelf-quizzing for each page, with convenient same-page answer keysDiscover the anatomical structure of the following poses: Flying Crow PoseScorpion PoseBird of Paradise PoseMaster baby grasshopper poseSage Half Bound Lotus PoseLotus in Shoulder Stand PoseRested half pigeon poseCrow PoseOne handed tree poseOne Legged Wheel PoseKing Cobra PoseAnd many, many more...Joins thousands of yogis from all levels who have made their journey to master the asanas more fun, easy and efficient!Roll up and click "ADD TO CART" right now
Horse Anatomy Coloring Book
Looking for an easy, fun and effective way to demystify the structures of the horse?Coloring equine physiology and its structures is the most effective way to study the anatomy and functions of the horse. You assimilate information and make visual associations with key terminology when coloring in the Horse Anatomy Book, all while having fun!Whether you are following a veterinary anatomy course or just interested in the horse and its structures, let this book guide you.While other books give you the anatomy terminology immediately, our book is designed for convenient self-testing by providing the answer keys on the back of the same page so you can get the most out of your studies. Plus, the detailed illustrations of the horse's anatomical systems in a large page design without back-to-back drawings will make you say goodbye to bleed-through!The Horse Anatomy Coloring Book features: The most effective way to skyrocket your equine anatomical knowledge, all while having fun!Full coverage of the major systems of the horse to provide context and reinforce visual recognition50+ unique, easy-to-color illustrations of different anatomical sections of the horse with their terminologyLarge 8.5 by 11-inch single side paper so you can easily remove your coloringSelf-quizzing for each illustration, with convenient same-page answer keysDiscover the structures of the following sections of the horse: Skeletal systemMuscular systemDigestive systemCardiovascular systemNervous systemAny many, many more...Joins thousands of others who have made their studies more fun and efficient!Roll up and click "ADD TO CART" right now
Host-Directed Therapies for Tuberculosis
TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB.
Microbial Genomics in Sustainable Agroecosystems
In recent decades, significant advances in new methodologies like DNA sequencing and high-throughput sequencing have been used to identify microorganisms and monitor their interactions with different environments. Microbial genomics techniques are opening new approaches to microbiology by revealing how microorganisms affect human beings and the environment. This book covers four major areas: 1) Environmental microbial genomics, 2) Microbial genomics in human health, 3) Microbial genomics in crop improvement and plant health protection, and 4) Genome analysis of microbial pathogens. Within these areas, the topics addressed include: microbial genome diversity, evolution, and microbial genome sequencing; bioinformatics and microarray-based genomic technologies; functional genomics of bioremediation of soil and water from organic and inorganic pollutants and carbon management; functional genomics of microbial pathogens and relevant microorganisms; functional genomics of model microorganisms; and applied functional genomics. Given its scope, the book offers a comprehensive source of information on the latest applications of microorganisms and microbial genomics to enhance the sustainability of agriculture and the environment.
The Life, Letters And Labours Of Francis Galton (Volume Iii) Characterisation, Especially By Letters Index
An extraordinary inside view of one of Victorian science's most influential and controversial figures. A rich, vivid intellectual portrait. Karl Pearson's third volume, The Life, Letters and Labours of Francis Galton (Volume III), assembles characterisation chiefly through correspondence and a precise index, functioning as a scientific correspondence anthology and a historical letters archive that places readers amid the debates and discoveries of nineteenth-century Britain. As a scientific discovery biography it illuminates the intellectual currents of the Victorian science era and contributes to victorian intellectual history, tracing Galton's connections with Charles Darwin contemporaries and the development of ideas now central to the history of eugenics. The letters, carefully gathered and indexed by Pearson, reveal networks of exchange, methodological disputes and the private registers of a man whose work shaped statistics, psychometrics and social theory, without smoothing the controversies that have come to define his legacy. Pearson's analytical framing adds context and makes the correspondence usable as source material for research and reflection. Out of print for decades and now republished by Alpha Editions. Restored for today's and future generations. More than a reprint: a collector's item and a cultural treasure. Presented with curatorial care, this edition balances fidelity to the original with modern readability, and the thorough index turns the volume into an effective academic research reference for those engaged in galton and pearson studies or the wider history of science. Casual readers will discover an accessible route into Victorian intellectual history and nineteenth-century Britain; archivists and historians will prize the book as a historical letters archive and a primary resource for study of the history of eugenics and methodological change. Suitable for a university library collection and for classic-literature collectors attracted to a victorian biography collection, it offers both the texture of primary evidence and the framing of rigorous scholarship.
Genetic Diversity of Soil Bacterial Communities
The book contains research articles and reviews recently published online for the MDPI journal Diversity, in the Special Issue "Genetic diversity of soil bacterial communities". The issue aimed to collect up to date information from the international scientific community to get insight in the "black box", as soil has been defined in the last decades, focusing in detail on the role that the microbial communities have in soil processes such as carbon and nutrient fluxes and on their genetic and functional diversity. The book meets the interests of scientific communities directly involved in the topics investigated, as well as of PhD students, scholars, professional organizations interested in improving their knowledge on a group of organisms considered vitally important to the maintenance and sustainability of the biosphere, where soil has a key role as an important natural resource.
Seasonal Abundance of Insect Pest and Varietal Performance of Country Bean in Sylhet Sadar, Bangladesh
The study was conducted in Entomology field in SAU to know the incidence of insect pests at different growth stages, intensity of infestation, relative abundance, effect of yield due to different insect during winter and summer season under natural condition. In both season, 4 insect pests found in country bean. The pod infestation by pod borer and aphids in experiment field. Only the field cricket attacked in seedling in summer season. In shoot borer and epilachna beetle infested in leaf and shoot of country bean. Aphid and pod borer were major pests of country bean field. Aphid infested in all stages of country bean but pod borer mainly infested during flowering and fruiting stages of country bean stages. The experiment was laid out in Randomized Complete Design (RCBD) with three replications. The research field was divided into three blocks and each block represented one replication. The accumulated population density was the highest observed aphid (408.74) and the lowest was recorded in shoot borer (20.66) in winter season. Similarly, the accumulated population density was the highest recorded aphid (205.89) and the lowest was observed field cricket (3) summer season. Total number of arthropods was recorded 734 and 346 in winter and summer season; respectively. The highest number of aphids was observed and relative abundance was recorded 55.58% in winter and in summer the highest number of aphids was noted and relative abundance was observed 59.24%. In winter bean flowering stage was recorded the highest number of aphids (150) and the lowest number was recorded in vegetative stage (120); in epilachna beetle was recorded flowering stage was recorded the highest (31) number and the lowest number was recorded in vegetative stage (24); followed by the shoot borer mainly infested in vegetative stage and lowest the others two stages and pod borer infested the highest (235) number in reproductive stage and nil in vegetative stage and moderate number in flowering stage.
Marine Biologically Active Compounds as Feed Additives
This Special Issue presents high-quality research papers as well as review articles addressing recent advances in the use of marine bioactives in animal nutrition. The marine environment constitutes a relatively untapped source of biologically active compounds that can be applied in various areas, such as improvement of animal performance, health maintenance, and disease prevention. Numerous marine-based compounds isolated from marine organisms (especially seaweeds) have diverse biological activities, including antioxidative, anti-inflammatory, antibacterial, antifungal, and antiviral activities that can be beneficial to animal health. Additionally, the application of marine bioactives as feed additives can increase the nutritional value of products of animal origin. In this Special Issue, the main attention was focused on seaweeds and their application in poultry (laying hen and broiler chickens) and pig feed. The suitable processing of marine resources required for their optimal use as feed/feed additives was underlined. The contained publications present scientific evidence for the use of various seaweeds as feed additives that improve health (enhanced immunity, prebiotic effect), growth performance, and production. Inclusion of this unconventional material in animal nutrition can enrich products with active compounds, such as micro- and macroelements, polyunsaturated fatty acids, and pigments which are beneficial for consumers.
Quality and Safety of Meat Products
Food safety is a major problem around the world, both with regard to human suffering and with respect to economic costs. Scientific advances have increased our knowledge surrounding the nutritional characteristics of foods and their effects on health. This means that a large proportion of consumers are much more conscious with respect to what they eat and their demands for quality food. Food quality is a complex term that includes, in addition to safety, other intrinsic characteristics, such as appearance, color, texture and flavor, and also extrinsic characteristics, such as perception or involvement.
Advancing Knowledge on Cyanobacterial Blooms in Freshwaters
Cyanobacterial blooms are a water quality problem that is widely acknowledged to have detrimental ecological and economic effects in drinking and recreational water supplies and fisheries. There is increasing evidence that cyanobacterial blooms have increased globally and are likely to expand in water resources as a result of climate change. Of most concern are cyanotoxins, along with the mechanisms that induce their release and determine their fate in the aquatic environment. These secondary metabolites pose a potential hazard to human health and agricultural and aquaculture products that are intended for animal and human consumption; therefore, strict and reliable control of cyanotoxins is crucial for assessing risk. In this direction, a deeper understanding of the mechanisms that determine cyanobacterial bloom structure and toxin production has become the target of management practices. This Special Issue, entitled "Advancing Knowledge on Cyanobacterial Blooms in Freshwaters", aims to bring together recent multi- and interdisciplinary research, from the field to the laboratory and back again, driven by working hypotheses based on any aspect of mitigating cyanobacterial blooms, from ecological theory to applied research.
The Life, Letters And Labours Of Francis Galton (Volume Ii) Researches Of Middle Life
An intimate portrait of ambition and inquiry. He pursues truth with rigour. Karl Pearson's The Life, Letters and Labours of Francis Galton (Volume II: Researches of Middle Life) is a masterly victorian scientific biography that reads as a personal and public historical letters collection and as an intelligent intellectual history book. It concentrates on Galton's researches into heredity and eugenics, and preserves scientific correspondence that traces the networks of enquiry central to british science history. Restored texts and meticulous notes make it an indispensable academic research reference and a welcome addition to any university library collection. Set amid the bustle of nineteenth century England and the debates of victorian era science, Pearson situates Galton among charles darwin contemporaries while offering a vital source for francis galton studies. Out of print for decades and now republished by Alpha Editions. Restored for today's and future generations. More than a reprint - a collector's item and a cultural treasure. Pearson's intimate scholarship remains of literary and historical significance: the book preserves first-hand scientific correspondence and situates Galton at the nexus of ideas that shaped Victorian era science. Accessible enough for curious readers yet rigorous as an academic research reference, it belongs on the shelf of anyone studying nineteenth century England, in classic-literature collections, and in university library collections supporting francis galton studies. Pearson writes with forensic attention to evidence and with a scholar's insistence on context; the result is neither uncritical praise nor polemic, but a textured account that makes the period's scientific priorities and ethical tensions plain to modern readers. The letters themselves are lively and often unexpectedly candid, giving colour to the debates about measurement, statistical method and the social consequences of scientific theory. For casual readers curious about victorian era science and for collectors seeking a distinguished heritage title, this edition offers both readable narrative and dependable materials for further study.
Seed Dormancy
The appearance of the new generation in higher plants is ensured by the presence of viable seeds in the mother plant. A good number of signaling networks is necessary to provoke germination. Phytohormones play a key role in all stages of seed development, maturation, and dormancy acquisition. The dormancy of some seeds can be relieved through a tightly regulated process called after-ripening (AR) that occurs in viable seeds stored in a dry environment. Although ABA is directly involved in dormancy, recent data suggest that auxin also plays a preponderant role. On the other hand, the participation of reactive oxygen species (ROS) in the life of the seed is becoming increasingly confirmed. ROS accumulate at different stages of the seed's life and are correlated with a low degree of dormancy. Thus, ROS increase upon AR and dormancy release. In the last decade, the advances in the knowledge of seed life have been noteworthy. In this Special Issue, those processes regulated by DOG1, auxin, and nucleic acid modifications are updated. Likewise, new data on the effect of alternating temperatures (AT) on dormancy release are here present. On the one hand, the transcriptome patterns stimulated at AT that encompasses ethylene and ROS signaling and metabolism together with ABA degradation were also discussed. Finally, it was also suggested that changes in endogenous γ-aminobutyric acid (GABA) may prevent seed germination.
Pluripotent Stem Cells in Eye Disease Therapy
1. Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE perspective2. Utility of induced pluripotent stem cell-derived retinal pigment epithelium for an in vitro model of proliferative vitreoretinopathy3. Developing cell-based therapies for RPE-associated degenerative eye diseases4. Pluripotent Stem Cell derived 3D Ocular Tissue Transplantation - role of immune system in cell integration5. Use of Stem Cells to model optic nerve degeneration diseases 6. Surgical approaches for RPE/retina7. 3D Engineering Ocular Tissues for Disease Modeling and Drug TestingIndex
Quintessence - Life’s Essential Balance Between Stability, Novelty and Fateful Encounters
We're two scientists trying to understand Life and Evolution. On a fundamental level, we may all wonder if Life is somehow hard-wired into the structural design of the universe. This naturally leads to the question of what is it that is hard-wired into this vast universe that produces Life? Are there yet unknown chemistries that we haven't explored? Are there unknown physical laws that govern the flow of energies into Life's multiple forms? We attempt to answer these questions and more about Life's most basic principles. This book is meant to engage and catalyze the reader's mind on a journey of discovery, wonder and awe as we explore and marvel at the wonders of Life and Evolution.
V疇rt Levande Universum
Hur uppkom v疇r v瓣rld och v瓣rldsordning? Vad 瓣r det f繹r enorm kraft som f疇tt och f疇r v疇rt Universum med alla sina miljarders miljarder galaxer, stj瓣rnor och planeter etc att, enligt m疇nga observationer och m瓣tningar, expandera och t.o.m. rotera? Och all information, alla atomer och neutroner, protoner och elektroner? Hur uppkom de; hur 瓣r v疇r v瓣rld och verklighet egentligen ordnad, hur fungerar det och vad 瓣r dess 繹de? Finns kanske ocks疇 ett Antiuniversum med antigalaxer, antiplaneter och antim瓣nniskor?! Och inte minst: N瓣r, varifr疇n och hur uppkom Livet? P疇 v疇r planet och i Universum 繹verhuvudtaget. Och kanske andra universa. Endast liv kan skapa liv, 瓣r ju en gammal sanning. Betyder det att v疇rt Universum som skapat allt liv sj瓣lvt 瓣r levande? Detta 瓣r n疇gra fr疇gor som kommer att besvaras i denna skrift, inte i varje i detalj, men n瓣stan.
Symbiosis as a Source of Evolutionary Innovation
These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty.A departure from mainstream biology, the idea of symbiosis--as in the genetic and metabolic interactions of the bacterial communities that became the earliest eukaryotes and eventually evolved into plants and animals--has attracted the attention of a growing number of scientists.These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty. They include reports of current research on the evolutionary consequences of symbiosis, the protracted physical association between organisms of different species. Among the issues considered are individuality and evolution, microbial symbioses, animal-bacterial symbioses, and the importance of symbiosis in cell evolution, ecology, and morphogenesis. Lynn Margulis, Distinguished Professor of Botany at the University of Massachusetts at Amherst, is the modern originator of the symbiotic theory of cell evolution. Once considered heresy, her ideas are now part of the microbiological revolution. ContributorsPeter Atsatt, Richard C. Back, David Bermudes, Paola Bonfante-Fasolo, Ren矇 Fester, Lynda J. Goff, Anne-Marie Grenier, Ricardo Guerrero, Robert H. Haynes, Rosmarie Honegger, Gregory Hinkle, Kwang W. Jeon, Bryce Kendrick, Richard Law, David Lewis, Lynn Margulis, John Maynard Smith, Margaret J. McFall-Ngai, Paul Nardon, Kenneth H. Nealson, Kris Pirozynski, Peter W. Price, Mary Beth Saffo, Jan Sapp, Silvano Scannerini, Werner Schwemmler, Sorin Sonea, Toomas H. Tiivel, Robert K. Trench, Russell Vetter
Science and Art are Based on the Same Principles and Values
A key, critical figure in contemporary biology, a giant in scientific thought, and an author of revolutionary studies alongside hundreds of original works, Professor Antonio Lima-de-Faria leaves us his scientific testament while approaching his 100th year of life. As a "lonely wolf howling in the immensity of the night," he launches his straightforward warning. His message is for those who have ears to hear in a world where "there is no place for the meek." "At present a wave of obscurantism is spreading over Western countries affecting both science and art in a deadly way." "Modern technology has been most successful in transforming our daily lives and in allowing us to conquer outer space. These impressive achievements have, to a large extent, made us dumb, making it difficult to perceive the danger that lies ahead. Hence, there is a pressing need to bring forward the original sources in which, leading scientists and renowned artists, explained the principles that they followed in their discovery of novel phenomena and in the creation of unique works of art. It turns out that both types of minds speak the same language. There is a basic denominator that unites the human endeavor."