Molecular Imaging for Brain Diseases
This volume aims provides timely reviews with special focus on the clinical aspects of brain molecular imaging. The chapters reflect the interdisciplinary nature of the field detailing, glutamate receptor imaging, tau and amyloid imaging, glucose metabolism, opioid receptor, dopamine receptor imaging, brain metabolite measurements by 1H-MRS, and analytical methods using artificial intelligence, which have become extremely important in recent years. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Molecular Imaging for Brain Diseases provides methods to navigate this complex field and inspire a deeper appreciation for the brain's molecular underpinnings.
Uncommon Ground
'A curious-minded and subtle intervention in the politics of the countryside' Sunday Times 'Galbraith spent three years investigating the truth about rural Britain and how we treat it. Uncommon Ground is the brilliant result' Daily Telegraph 'Very funny. Acutely observed. An attempt to look beyond the usual clich矇s of country life' Observer "Brilliant. This book is a sort of necessary clever trespass itself, on everyone's notions about 'our land'." Country Life "Filled with voices from people who don't always make the headlines in the UK land access debate." Scotsman The countryside is under increasing pressure and people, the science shows, need nature. Access to the countryside is essential for our health, our happiness and our future. But does nature need us?In January 2023, the largest land access demonstration since the 1930s took place on a bright wintery morning on Dartmoor. The access movement demands that the countryside be thrown open. This, they argue, would help nature by giving the public the opportunity to hold farmers and wealthy landowners to account.But would it really work for Britain's growing population to spill out across the countryside, and is access quite as restricted as we are led to believe?In Uncommon Ground, Patrick Galbraith takes us on an extraordinary tour of rural Britain, from the Hebrides to Devon, and from Anglo-Saxon England to the present day. To uncover the truth and fully understand our deep connection with the land, he meets farmers, Irish Travellers, politicians, salmon poachers, and the nation's most-hated landowners, as well as activists calling for a total abolition of the right to own land.In his much-celebrated style, Galbraith works hard to listen to those who often don't get listened to. This raking survey of our fast-changing country, reveals the essence of rural Britain's soul. Uncommon Ground argues that what matters is not greater access but how we engage with the land and demands that landowners give us more opportunities to do so, while also giving endangered wildlife the right to tranquility.
Elusive Cures
A neuroscientist's bold proposal for tackling one of the greatest challenges of our time--brain and mental illnesses Brain research has been accelerating rapidly in recent decades, but the translation of our many discoveries into treatments and cures for brain disorders has not happened as many expected. We do not have cures for the vast majority of brain illnesses, from Alzheimer's to depression, and many medications we do have to treat the brain are derived from drugs produced in the 1950s--before we knew much about the brain at all. Tackling brain disorders is clearly one of the biggest challenges facing humanity today. What will it take to overcome it? Nicole Rust takes readers along on her personal journey to answer this question. Drawing on her decades of experience on the front lines of neuroscience research, Rust reflects on how far we have come in our quest to unlock the secrets of the brain and what remains to be discovered. She shows us that treating a brain disorder is more like redirecting a hurricane than fixing a domino chain of cause and effect, arguing that only once we embrace the idea of the brain as a complex system do we have any hope of finding cures. Rust profiles the pioneering ideas about the brain that are driving research at the cutting edge to illuminate exactly how much we know about disorders such as Parkinson's, epilepsy, addiction, schizophrenia, and anxiety--and what it will take to eradicate these scourges. Elusive Cures sheds light on one of the most daunting challenges ever confronted by science while offering hope for revolutionary new treatments and cures for the brain.
Thinking Like a Human
A bright and timely book that celebrates the value of the human mind AI is at the forefront of everyone's minds: from students and artists, to CEO's and service workers. But what exactly is AI, and how does it influence our everyday lives? And more than that, what does it mean for our future? Is there a way for us to retain our "humanness" in a world ever-reliant on tech?This groundbreaking book argues that the key technology we use to make strategic, political, and ethical decisions is flawed. As we race headlong into a future where we outsource all of our problem solving to artificial intelligence, the greatest threat to humanity is not superintelligent machinery, but a lack of trust in the power of our own minds. This book offers a new way forward--what Dr. Weitzner calls "artful intelligence"--a philosophy that celebrates our humanness and can help each of us make better decisions and create a healthier relationship with the world around us.In these pages, the author walks us through how AI often fails and how that affects our lives. But readers will also meet the rockstars, inventors, and business leaders who embody artful intelligence and are changing our world for the better in an era rampant with AI malpractice--while being taught how to do the same.
Beach Rambles in Search of Seaside Pebbles and Crystals
A Guide to the Scientific Knowledge of Things Familiar
Mastering the Patch Clamp Technique: A Practical Guide
The patch clamp technique is one of the most important electrophysiological methods in use today. Its application in basic biomedical research has provided significant insights into the function and properties of ion channels, making it equally indispensable in applied pharmacological research. This book is the English edition of the popular German introduction to the patch clamp technique. This introductory book serves as a practical guide for teachers and students, offering clear and practical instructions on patch clamp recordings. The authors provide essential information to establish and successfully apply this method in the laboratory. The book covers the basics of measurements, the detailed setup of a patch clamp rig and how to carry out typical recordings. It also includes concrete tips and tricks to help with troubleshooting, making it an indispensable resource. The book not only highlights the enormous potential of the method for the study of ion channels and cell signaling, but also provides an introduction to the major developments and variations of the technique. The book is aimed at advanced students of biology, biochemistry, medicine, pharmacy and related disciplines as well as scientists who want to better understand and/or acquire the technique.
The 50 Greatest Scientists
In this stunning jacketed hardback, Jon Balchin introduces 50 of the world's most influential scientists of all time and explains their revolutionary theories, showcased with full-color photography. Scientific discoveries have shaped our world as we know it today. In this beautifully illustrated book, Jon Balchin examines the achievements of 50 of history's greatest scientists: the men and women who gave us geometry (Euclid), the telescope (Galileo), the periodic table (Mendeleev) and radium (Marie Curie) as well as those whose work has helped us understand our world and the cosmos in far greater detail than ever before, such as Albert Einstein, Edwin Hubble, Rosalind Franklin and Stephen Hawking. Together, they show how scientists' work has influenced our way of life as well as our ability to combat disease and comprehend the deceptive complexities of nature and human beings. Perceptive and informative, this book is a fascinating introduction to the way science has developed over millennia. Includes: - Full-color photographs and illustrations of famous inventions - Concise professional biographies of the scientists listed- Entries arranged in chronological order for easy reference ABOUT THE SERIES: The 50 Greatest series brings together highly visual reference guides, each exploring 50 of the most influential figures across a certain discipline. These rich biographical profiles outline their key achievements, influences and impact on the industry, accompanied by stunning full-color photography.