Forest Plant, Soil, Microorganisms and Their Interactions
Forests are the most important terrestrial ecosystems in the world, providing diverse ecosystem services including food production, biodiversity conservation, sand storm prevention, water and soil conservation, nutrient cycling, and carbon sequestration. It is well known that plants, soil, and microbes in forest ecosystems do not exist in isolation; rather, they are intricately interconnected. Their complex coupling interrelationships are crucial for driving ecological processes and ecosystem functions in forest ecosystems. This reprint presents several new results on plant functional traits, soil nutrient cycling, soil microbial diversity, and plant-soil microbe interactions from the perspective of forest succession, elevation, climate warming, atmospheric N deposition, land use changes, and application of soil microbial inoculants, aiming to promote forest management.
Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine
Electric, magnetic, and electromagnetic fields (EMFs) are widely used in everyday life, as well as in specific occupational environments and clinical settings. EMF-based technologies employ different parts of the spectrum, from static fields to low- and high-frequency EMFs encompassing millimeter waves and THz.Exposure to these fields raises concerns about the possible effects on human health. On the other hand, biomedical applications of non-ionizing radiation are successfully employed for diagnosis and therapy (e.g., electroporation-based treatments, microwave hyperthermia, transcranial magnetic stimulation, etc.). There is a significant amount of interest in evaluating the associated interaction mechanisms, which are also relevant in fostering the development of new biomedical applications and the optimization of the existing ones.This Special Issue, entitled "Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 2nd Edition", includes contributions focusing primarily on the therapeutic and diagnostic applications of EMFs. In vitro, in silico, and human studies are presented where the aim was either to optimize technical aspects of the applications, or to provide insights into biological, biophysical, electrical or electrochemical mechanisms. Overall, these contributions present an overview of the broad spectrum of established and potential applications of electromagnetics in the biomedical field.
False Messiah
Ever since The Origin of Species appeared in 1859, Charles Darwin's followers have co-opted him as the patron saint of materialism. In False Messiah, longtime Darwinist and agnostic Neil Thomas looks at how Darwinism triumphed, and he challenges the official story with an exploration richly informed by his expertise in rhetoric and cultural history. What of Darwinism's present status? Like Marxism-that other great materialist theory of the Victorian age-Darwinism has become "the God that failed." As Thomas shows, although Darwinism has done incalculable damage to our culture, there is hope for renewal in contemporary scientific findings that are reinvigorating the argument to design as well as in what amounted to an ingenious flanking movement against modern materialism-the spiritually charged philosophy of nature developed in the poetry of William Wordsworth.
On Muscle
From the bestselling author of Why We Swim comes a mind-expanding exploration of muscle that will change the way you think about what moves us through the world. "Remarkable ... A singular book about the true meanings of strength and flexibility, about our ability to define who we are and who we might be." --Ed Yong, New York Times bestselling author of An Immense World and I Contain Multitudes In On Muscle, Bonnie Tsui brings her signature blend of science, culture, immersive reporting, and personal narrative to examine not just what muscles are but what they mean to us. Cardiac, smooth, skeletal--these three different types of muscle in our bodies make our hearts beat; push food through our intestines, blood through our vessels, babies out the uterus; attach to our bones and allow for motion. Tsui also traces how muscles have defined beauty--and how they have distorted it--through the ages, and how they play an essential role in our physical and mental health. Tsui introduces us to the first female weightlifter to pick up the famed Scottish Dinnie Stones, then takes us on a 50-mile run through the Nevada desert that follows the path of escape from a Native boarding school--and gives the concept of endurance new meaning. She travels to Oslo, where cutting-edge research reveals how muscles help us bounce back after injury and illness, an important aspect of longevity. She jumps into the action with a historic Double Dutch club in Washington, D.C., to explain anew what Charles Darwin meant by the brain-body connection. Woven throughout are stories of Tsui's childhood with her Chinese immigrant artist dad--a black belt in karate--who schools her from a young age in a kind of quirky, in-house Muscle Academy. On Muscle shows us the poetry in the physical, and the surprising ways muscle can reveal what we're capable of.
Rethinking Cancer
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. Thanks to dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet it is still unclear how to use this knowledge for treatment success. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and noncoding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.
Long Non-Coding RNAs - Function, Mechanisms, and Applications
LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.
The Healing Root
This book presents a comprehensive investigation into the antioxidant and antidiabetic potential of Pimpinella tirupatiensis, an endemic medicinal plant, with a focus on its protective effects against streptozotocin (STZ)-induced diabetic nephropathy in albino rats. It explores the role of oxidative stress in diabetic kidney damage and evaluates the therapeutic efficacy of the plant through in vitro antioxidant assays, biochemical analyses of both enzymatic and non-enzymatic antioxidants, and detailed histopathological examinations. By integrating traditional knowledge with modern scientific approaches, the book highlights the plant's promising nephroprotective and antioxidative properties, offering valuable insights for researchers and practitioners in the fields of phytomedicine, pharmacology, and diabetes management.
Enzymes
This book summarizes mountains of research by various scientists in the field of general biochemistry, with an emphasis on enzymes which make all the important molecules in our body, such as DNA, proteins, etc. Enzymes are also essential for removing all toxic chemicals that inadvertently enter our body. All metabolic reactions in our body are performed by enzymes. But perhaps, most importantly, it should give the reader a satisfying feeling of knowing: "Aha! That is how my cells work."
Biotechnology
The developmental trends in biological sciences indicate there is a plethora of possibilities concerning the study of microorganisms and its applicability in creating the next generation of biological warfare agents. Both historical and recent events show the potentially devastating effect of using biological warfare agents and the terror they cause among the populace. Even more alarming is that the exponential growth in biotechnology could transform the conventional biological warfare agents into a much more lethal bioweapon using genetically engineered pathogens. Nations, groups, and individuals that have the resources, capabilities, and knowledge to develop this biotechnology in the year 2035 will have the global arms race advantage.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Microbes and the Microbe Killer
Dive into the late 19th century with William Radam's "Microbes and the Microbe Killer," a fascinating and controversial treatise on the nature of disease and its purported cure. Radam, a self-proclaimed medical innovator, details his theories about microbes as the root cause of all ailments and champions his own invention, "Radam's Microbe Killer," as the universal remedy. This book offers a unique window into the world of alternative medicine and patent remedies during a period of rapid scientific advancement and intense medical debate. Whether viewed as a groundbreaking discovery or a questionable elixir, Radam's work sparked considerable public interest and continues to intrigue those interested in the history of medicine, scientific controversies, and the enduring quest for health and wellness. "Microbes and the Microbe Killer" is a valuable historical document reflecting the beliefs and practices of its time.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Electro-biology; or, The Doctrine of Impressions
"Electro-Biology; or, The Doctrine of Impressions" explores the fascinating intersection of early scientific inquiry and the emerging field of psychology in the mid-19th century. Authored by John A. Wroe with contributions from John Reid, M. D., this volume delves into the principles of electro-biology, a precursor to hypnotism and the study of suggestion. The book examines the effects of mental impressions on the human body, reflecting a time when the boundaries between science, philosophy, and spirituality were more fluid. Readers interested in the history of psychology, mesmerism, and the evolution of scientific thought will find this work a compelling glimpse into the past. Discover the ideas that shaped early investigations into the power of the mind and its influence on physical well-being.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Biotechnology
The developmental trends in biological sciences indicate there is a plethora of possibilities concerning the study of microorganisms and its applicability in creating the next generation of biological warfare agents. Both historical and recent events show the potentially devastating effect of using biological warfare agents and the terror they cause among the populace. Even more alarming is that the exponential growth in biotechnology could transform the conventional biological warfare agents into a much more lethal bioweapon using genetically engineered pathogens. Nations, groups, and individuals that have the resources, capabilities, and knowledge to develop this biotechnology in the year 2035 will have the global arms race advantage.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
On Some New And Little Known Diatoms
"On Some New And Little Known Diatoms" by Per Teodor Cleve offers a detailed exploration into the world of diatoms, microscopic algae found in marine environments. This scientific work delves into the identification and classification of both newly discovered and less familiar diatom species. Cleve's research provides valuable insights into marine biology, oceanography, and paleontology. This book is an essential resource for scientists, researchers, and students interested in understanding the diversity and significance of diatoms in aquatic ecosystems and their historical record.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Arbidol
Antiviral drug development has led to significant advances in the control of globally prevalent viral infections by the hepatitis C (HCV) and the human immunodeficiency viruses. Nonetheless, there are current gaps in the armamentarium against global viral infections due to some herpes viruses, the hepatitis B virus, and the deadly filovirus Ebola and arenavirus Tacaribe responsible of outbreaks of hemorrhagic fever in emerging countries. Arbidol (ARB) is a cost-effective antiviral with broad-spectrum activity, administered for decades in Russia and China against flu. We showed that ARB inhibits HCV infection, and has potent antiviral activity against the Ebola, Tacaribe, hepatitis B and human herpes-8 viruses. Since these viruses have divergent life cycles, we posit that ARB may exhibit varied modes of action against different viruses. Careful dissection of molecular mechanisms of action of ARB against HCV and the Ebola virus revealed that ARB blocked viral entry. ARB might, therefore, constitute a pharmacological approach against globally prevalent viruses, and an affordable molecule for emerging countries in urgent need for effective antiviral therapies.
Risk of Thrombosis during and after COVID Infection
The novel coronavirus known as SARS-CoV-2 is a respiratory virus that presents with symptoms such as a non-productive cough (60-80%), fever (90%) and shortness of breath (19-40%) and is responsible for the 2019-2020 global coronavirus disease (COVID-19) pandemic. Although most patients experience mild or no symptoms, severe disease is associated with thromboembolic complications and respiratory failure. There is an observed rise in the clinical manifestations of the disease 7 to 14 days after initial symptom onset and also associated with thrombotic complications. Understanding the thrombotic manifestations of the virus is important for patient management.
Exploring the Borderlands
This study reproduces one "Report of Meetings" & six "Bulletins" from the Committee on Common Problems of Genetics, Paleontology, & Systematics. This Committee operated as an administrative unit of the National Research Council, part of the U.S. Nat. Acad. of Science. It was launched in 1943, blossomed for two years, then served as a cornerstone for other cooperative projects. The Committee provided a crucial foothold for those seeking a synthetics view of evolution in 1940s America. These forgotten documents show the Committee at work: building coalitions, defining priorities, & negotiating a common vision. They also show factions within the Committee competing for the leadership of this emerging community. Photo.
Heterozygosis in Evolution and in Plant Breeding
"Heterozygosis in Evolution and Plant Breeding," Volume 243, explores the significance of heterozygosity in the fields of evolutionary biology and agricultural science. Authored by Edward M. East and Herbert Kendall Hayes, this work delves into the genetic principles underlying heterozygosis and its implications for both natural selection and crop improvement.The book examines how the genetic diversity arising from heterozygosity contributes to the adaptability and resilience of plant species. It also investigates the practical applications of these principles in plant breeding programs, offering insights into the development of higher-yielding and more robust crop varieties. This volume remains a valuable resource for geneticists, botanists, and agricultural scientists interested in the intersection of genetics, evolution, and plant breeding.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The Mutation Theory; Experiments and Observations on the Origin of Species in the Vegetable Kingdom
"The Mutation Theory; Experiments and Observations on the Origin of Species in the Vegetable Kingdom, Volume 2" presents a detailed exploration of Hugo de Vries' groundbreaking work on mutation theory. This volume builds upon his experimental research and observations concerning the origin of new species within the plant kingdom. The work provides insights into the mechanisms of evolution and heredity, focusing on the role of mutations as a driving force. Authored by Hugo de Vries, with contributions from John Bretland Farmer and A. D. Darbishire, this book remains a valuable resource for botanists, geneticists, and anyone interested in the history of evolutionary thought. It offers a deep dive into the experimental evidence and theoretical framework that shaped early 20th-century understanding of species evolution.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Obstetrics and Gynecology Medicine
"Obstetrics and Gynecology Medicine: From Bench to Bedside" presents a curated collection of cutting-edge research that bridges the gap between basic science and clinical practice in women's health. Spanning topics such as reproductive biology, pregnancy complications, gynecologic oncology, and assisted reproduction, this volume showcases innovative approaches and interdisciplinary collaborations that are redefining the future of obstetrics and gynecology.
Studies on the Marine Pleistocene
This is a print on demand edition of an important, hard-to-find publication. Over 50 illustrations.
Systematics and Evolution of the Moinidae
This is a print on demand edition of an important, hard-to-find publication.
Studies on Chromosomes and Nuclear Division
This is a print on demand edition of an important, hard-to-find publication. Illustrations.
Chromosomes in the Spermatogenesis of the Hemiptera Heteroptera
This is a print on demand edition of an important, hard-to-find publication.
Whole Life Cycle of Chromosomes and Their Coiling Systems
Chromosomes play so important a role in heredity & development that it is desirable to know their entire life cycle since this knowledge will provide a basis for better understanding of their behavior. Contents of this study: Introduction; The genus "Holomastigotoides"; Species of "Holomastigotoides" in "Prorhinotermes"; "Holomastigotoides tusitala" species novum; "Holomastigotoides diversa" species novum; Centrioles & achromatic figure; Relation of chromosomes to nucleoli; Relation of chromosomes to nuclear membrane; Single chromatids; Double chromatids; Discussion; Summary; & References. 35 plates. This is a print on demand edition of an important, hard-to-find publication.
Henrik Kroyer's Publication on Pelagic Marine Copepoda
This is a print on demand edition of a hard to find publication.
Autobiographical Ana of Robley Dunglison, M.D.
This is a print on demand edition of an important, hard-to-find publication. 14 plates.
Environmentally-Friendly Pest Control Approaches for Invasive Insects
This reprint aims to present innovative and sustainable strategies to manage invasive insect species, while minimizing ecological disruption. This collection emphasizes biological control, genetic insights, and novel biochemical interventions. It also showcases recent advances in sustainable strategies to mitigate the impact of invasive insect species. Emphasizing ecological safety and specificity, the contributions focus on biological control agents, host plant resistance, molecular targets, and sublethal effects of pesticides as alternatives to conventional chemical control. Control methods demonstrated here show the potential for precision pest management that reduces non-target effects and environmental contamination. Looking ahead, the development of genetic and behavioral control strategies, combined with ecological modeling and biotechnology, will be essential for designing robust, environmentally sound management programs. This reprint provides a valuable foundation for future interdisciplinary approaches in invasive insect control.
Dietary Habit, Gut Microbiome and Human Health
As a complex and dynamically changing ecosystem, the human gut microbiome evolves with the host and participates in metabolism, immunity, and neurological function. The influence of dietary habits on the composition of the gut microbiome is undoubtedly significant. Many studies have focused on the role of changes in the structure and function of the gut microbiome in the pathogenesis of various diseases, such as metabolic diseases, neurodegenerative diseases, cardiovascular and cerebrovascular diseases, and tumors. Such studies have also provided ideas for the prevention and treatment of related diseases from the perspective of the gut microbiome and its derivatives.
F. A. Smitt, Marine Bryozoa, and the Introduction of Darwin Into Sweden
This is a print on demand edition of an important, hard-to-find publication.
Contrasts in Scientific Style
Recounts the various styles of leadership shown by several prominent German chemists and biochemists during the period 1830 to 1914. Featured particularly are chemists Liebig, Baeyer and Emil Fischer and biochemists Hoppe-Seyler, Kuhne and Hofmeister. In a final chapter, Fruton considers the relevance of the conclusions drawn from the style of these 19th- and early 20th-centuy men to the styles of more recent research groups in the chemical and biochemical sciences. Special emphasis is placed on their influence on their scientific progenies in Germany, and in England, Russia, and the U.S. Attention is given to the individual contributions of the junior members of these scientific groups to the growth of knowledge within their disciplines.
Computational Genomics and Structural Bioinformatics in Microbial Science
Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics.
The Mastery of Bile Duct Injury
The Mastery of Bile Duct Injury is a comprehensive medical reference that explores various aspects of biliary injuries, encompassing anatomy, causes, classifications, clinical management, and surgical procedures, with a particular focus on complications arising from laparoscopic cholecystectomy. It not only provides a meticulous dissection of biliary injuries but also navigates through the labyrinth of diagnostic modalities and therapeutic approaches, illuminating a path towards enhanced patient care, surgical precision, and the future of research. Through its detailed examination, this authoritative reference serves as an invaluable resource for the complexities of biliary pathology empowering readers to navigate the challenges inherent in hepatobiliary surgery. Beginning with the historical evolution of cholelithiasis and extending to the impact of laparoscopic cholecystectomy, the book provides detailed insights into the intrahepatic and extrahepatic biliary systems, offering a foundation for understanding the complexities of biliary injuries encountered during surgical procedures. By addressing classification, management, and prevention strategies, the book serves as an invaluable resource for optimizing patient outcomes and minimizing complications in hepatobiliary surgeries.
Environmental Pollution and Cardiovascular Diseases
Environmental Pollution and Cardiovascular Diseases helps stakeholders enhance their knowledge about environmental pollution, weather conditions, climate change, and impacts on the cardiovascular system. The book further aims to ameliorate the global burden of cardiovascular deaths attributable to pollution by identifying trends in pollution-linked cardiovascular disease from the 1990s to present day. Overall, air pollution is estimated to cause about 34% of ischemic heart disease deaths. As these figures show no sign of declining, this book is a must-have for researchers, cardiologists, and others seeking to understand such an important etiological factor in so many cardiovascular illnesses.
The Cardiovascular System
The series Stem Cell Innovation in Health and Disease is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Cardiovascular System: From Bench to Bedside, Volume 6 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the cardiovascular system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compoundscreening paradigms, genetically engineered mice, and stem cell transplantation to treat cardiovascular system disorders and diseases. The volume is written for researchers and scientists in stem celltherapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.
Anti-Prostate Cancer Agents
Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications. This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents. This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders. So far, no book focusing on the topic has been published.
Narcolepsy
Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations. Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It's the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.
Structural and Functional Relationships in Prokaryotes
This book on bacterial physiology takes a balanced view of physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes the information gained from model systems. It also covers some experimental design issues in order to give readers an appreciation of the practical aspects and consequences of bacterial metabolism. The author stimulates readers to think about future developments in the field by presenting discussions from five world-famous bacterial physiologists.
Genomics-Guided Natural Products Discovery
Genomics-Guided Natural Products Discovery, Volume 717 focuses on how the genomics revolution has catalyzed a resurgence of interest in natural products research. With the explosion of new sequencing data to analyze, "genome-mining" tools have grown in sophistication. Hence, this volume captures the utility of these tools, serving as a how-to guide to lower the entry barrier for newcomers. Topics covered in this new release include Merging RODEO with genomic enzymology workflows to guide RiPP discovery, Exploring Ribosomally Synthesized and Post-translationally Modified Peptides through SPECO-Based Genome Mining, Genome Mining for Natural Products Made by Multinuclear Iron-dependent Oxidation Enzymes (MNIOs), and much more. Additional sections explore Genome-based discovery of polyketides generated by trans-acyltransferase polyketide synthases, Global genome mining in fungi using FunBGCe, Plant genome mining of burpitides from fused precursor peptides, Determining biosynthetic gene cluster boundaries thru comparative bioinformatics, Genome mining for bacterial terpenoids, Bioinformatics guided synthesis of natural product cyclic peptides, Overview of Genome Mining Strategies for Natural Products Discovery, and much more.
Bradykinin
Bradykinin: From Vasodilation to Neuroinflammation, the latest release in the Molecular Mediators in Health and Disease series is a comprehensive guide to the multi-functional peptide bradykinin and its impact across the human body. The early chapters provide an overview of the biosynthesis and metabolism of bradykinin, understanding its receptors and signaling pathways, and the therapeutic value of agonists and antagonists for targeting these. This book explores the role of bradykinin in vascular, renal, and brain function, as well as its influence on various conditions and diseases, including inflammation, pain, cardiovascular disease, renal disease, obesity, ischemic stroke, and infectious diseases, including Covid-19. In addition to its foundational knowledge, the book includes extensive coverage of bradykinin biochemistry and molecular biology. It highlights the therapeutic potential of bradykinin, making it an ideal reference for researchers working in these fields. The book serves as an invaluable resource for understanding the complex roles of bradykinin and its applications in medical research and treatment.
Fungal Macromolecule Applications in Life Sciences
Fungal Macromolecule Applications in Life Sciences: Biological Activity and Medical, Industrial, and Agricultural Applications provides a comprehensive guide to the diverse applications of fungal macromolecules, such as proteins, lipid carbohydrates, and nucleic acids. Chapters include an introduction to the background and importance of fungal macromolecules in various life science fields followed by a detailed overview of the methods for isolating, characterizing, and assessing the structural and functional characteristics of fungal macromolecules. The book also explores the practical applications of fungal macromolecules in the biomedical, agricultural, and industry sectors. In addition, the book explores potential uses of fungal macromolecules as pharmaceuticals, anti-cancer agents, and inhibitors of bacterial biofilm formation as well as in plant disease management, crop development, enzyme production, biosurfactants, and sustainable and functional food production. The book also examines the antimicrobial properties of fungal macromolecules and their role in managing disease and stimulating human immunology.
Fenugreek
Fenugreek is a miraculous medicinal herb that can be extremely potent for treating diabetes. It is also known for its medicinal properties that include relieving joint pain, lowering blood sugar level, restoring hair growth, as well as a dietary supplement for menstrual cramps and other conditions. Fenugreek is also a useful crop that helps fix nitrogen in the soil, an important nutrient for plant growth. Keeping in view the tremendous medicinal applications of fenugreek, this new book offers a comprehensive review of fenugreek, highlighting its nutritional and medicinal applications while also discussing methods for enhancing its yield and quality by improving the growth, physiological, and biochemical parameters of the plant.
