Translational Pulmonology
Translational research is essential to the advancement of medicine. Translational Pulmonology is an instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in pulmonary diseases, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.
Peptide Synthesis
This fully updated second edition provides a variety of procedures for synthetically producing peptides and their derivatives, ensuring the kind of precision that is important for successful synthesis. Chapters explore techniques relevant to drugs and vaccines are explored, such as conjugation and condensation methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Peptide Synthesis: Methods and Protocols, Second Edition aims to be comprehensive guide for researchers in the field.
Medicine in Homer
Medicine in Homer explores injuries in the great epic poems of Homer from the perspective of contemporary medical professionals. This foundational text describes injuries included in both Odyssey and The Iliad, drawing on connections to neurology, toxicology, and genetics in ancient Greek times. As human anatomy remains unchanged, a careful study of trauma anatomy in Homer provides a unique window into the epics, their composition, and the development of medicine available today.
Adenoviral Vectors for Gene Therapy
Adenoviral Vectors for Gene Therapy, Third Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. The fully updated and expanded third edition covers the basic biology of adenoviruses, highlights the potential use adenoviral vectors for the treatment of disease including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for vet applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine application and virotherapy, and oncolytic adenoviruses for anti-tumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.
Human-Centric Integration of 6g-Enabled Technologies for Modern Society
Human-Centric Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges serves as a comprehensive reference, addressing the information needs of professionals by providing deep information about the fundamentals and applications of 6G, enabling them to make informed decisions in the dynamic landscape of advanced communication technologies. In the 23 chapters, this book introduces the reader to the 6G technology, the evolution of wireless communication, and the integration of artificial intelligence; provides the use cases and applications of 6G technology and the insights into the challenges, future trends, and emerging technologies; and includes the applications of 6G technology in remote healthcare services, patient monitoring, and medical diagnostics. Human-Centric Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges redefines the way we connect, communicate, and collaborate with emerging technologies in this smart era of 6G technology. The title benefits from a collective wealth of knowledge and perspectives. This diversity enriches the content, providing readers with insights from various angles, setting it apart from publications authored or edited by a limited number of individuals.
Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations
Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations consolidates existing knowledge and research on patient safety and healthcare quality within vulnerable populations. It provides a comprehensive reference work, offering invaluable insights into this critical area. While information on related topics is scattered across various medical journals, this book bridges the accessibility gap by bringing this knowledge together in one authoritative volume. With a specific focus on hospitalized children and elderly adults, the book tackles a global issue that is particularly relevant in low-resource settings. In addition, it endeavors to address the unique challenges confronted by these populations, equipping stakeholders with vital information and strategies to better serve them. By exploring patient safety and healthcare quality, users will find this to be an invaluable resource that will shape the future of care provision for vulnerable populations.
3D Bioprinting in Cancer Applications
3D Bioprinting in Cancer Applications is an all-encompassing guide covering both fundamentals concerning biofabrication principles and intricate protocols for precise construction of biomimetric 3D systems supporting advanced cell culture development that faithfully recapitulates human disease hallmarks, with a special focus on cancer. This title fills the void left by existing publications overlooking essential aspects associated with combining multimodal medical imaging alongside precision cancer treatment options. In 12 chapters 3D Bioprinting in Cancer Applications leads the reader from an introduction to bioprinting technologies for cancer models, to models for immunotherapy and tumour-immune interaction, to biomimetrics 3D models to the applications of all these models in 3D bioprinted cancer models . 3D Bioprinting in Cancer Applications uniquely combines distinct modalities under a unified framework suitable not only for seasoned veterans but also newly minted trainees encountering these sophisticated practices for the first time.
Raising Genomics Literacy, Knowledge, and Awareness
Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.
Structural Inequalities and Health Outcomes for Chronic Disease
Structural Inequalities and Health Outcomes for Chronic Disease provides a conceptual framework for understanding existing evidence and guides the research around promising interventions and policies. In addition, it demonstrates how structural inequalities impact health and presents ways the healthcare system can participate in the solution. The book covers major chronic diseases and the special populations impacted by structural inequalities. Those working and studying public health, medicine, nursing, pharmacology will find this work of interest, as well as diversity and disparity scholars and health policymakers.
The Living Laboratory for Precision Medicine
The Living Laboratory for Precision Medicine: Solutions for Clinical Implementation provides a comprehensive resource on precision medicine through a convergence of innovation and solutions across multiple domains, including large population cohorts, artificial intelligence, genomics, phenomics, clinical trials, health economics and regulation exemplified by the living lab concept. This book is the first to look at precision medicine through the lens of last-mile solutions which make it broad in scope, practically relevant, and cutting-edge. The book explores the use of precision medicine to stimulate regional economic growth through a healthier population, savings on healthcare, and using innovation as a driver of economic development. The term precision medicine has been popularized by clinical, scientific, political, financial and technological interests as the biggest innovation to revolutionize healthcare. While over the past decade a few precision medicine-based solutions have come to fruition, the transformative leap in healthcare delivery and population benefit is yet to be realized. Current focus on precision medicine primarily focuses on patient stratification which constrains it to either a single disease area, a few sub-disciplines, or using a limited set of genomic technologies. While useful, experience over the last few years indicates precision medicine needs to be considered as a complex process with multiple feedback loops requiring significant interdisciplinary collaboration and innovation.
The Potential of Cancer Biomarkers
The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more. Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.
Rehabilitation Engineering, Assistive Technologies and the Future of Healthcare Using Robotics
Rehabilitation Engineering, Assistive Technologies and the Future of Healthcare Using Robotics​​​ presents the most recent developments in assistive technologies, rehabilitative engineering, and robotics, offering in-depth analysis of cutting-edge instruments and frameworks that have the power to transform rehabilitation and general well-being. The book provides insights into how the integration of assistive technology and robots can enhance healthcare delivery while also addressing global challenges related to healthcare accessibility, rehabilitation, the integration of advanced technologies, opportunities, and problems in assistive technologies. Sections are complemented by case studies from different countries.
Innovations in Cardio-Oncology
Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine examines the benefits of big data analysis and future advancements in individualized medicine in cardio-oncology. The book helps readers understand and maximize the benefits of existing AI algorithms by integrating AI and digital health technologies into the clinical workflow, exploring AI orchestration, testing of AI applications, processing steps, active involvement and collaboration of qualified employees, and many other factors. The book introduces cardio-oncology and describes the prevention, screening and surveillance in cardio-oncology, followed by several chapters on the emerging role of the applications of mHealth, telemedicine and Artificial intelligence in cardio-oncology. The book also highlights many societal and evidence-based recommended pathways for equitable digital health deployment and utilization in cardio-oncology care. It anticipates that exposing the potential for AI algorithms and innovative health tools widens the already existing healthcare disparities, including inequalities related to race, ethnicity, gender, socioeconomic level, lack of health insurance, linguistic and cultural barriers, systemic discrimination, and limited healthcare access.
Zuverl瓣ssige Gedanken Von Der Wahren Existenz, Natur Und Beschaffenheit Derer Polyporum
Zuverl瓣ssige Gedanken Von Der Wahren Existenz, Natur Und Beschaffenheit Derer Polyporum
Some Contributions On the Cytology of Taphrina Coryli Nishida On Corylus Americana
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Some Contributions On the Cytology of Taphrina Coryli Nishida On Corylus Americana
Polymers
The second edition of Macromolecular Chemistry broadens into two areas: biomacromolecules, Volume 1 and polymers, Volume 2. Polymers covers polymer history, polymerization reactions, polymer morphology, technology, characterization and testing, processing, and recycling. The book discusses the building blocks of synthetic polymers, comparison of macromolecules and polymers, polymer classification, and illustration of polymer chemical structures. Polymerization reactions such as step-growth polymerization and chain-growth polymerization are extensively discussed. It then presents tacticity, molecular interactions and polymer crystals. Biodegradable polymers, biomedical polymers, conducting polymers, electroluminescent polymers, water-soluble polymers, additives, adhesives, fibres, and coatings are described. The next section explores inorganic polymers such as polysilanes, polysiloxanes, and polyphosphazenes. The book then delves into polymer characterization and testing, including Infrared Spectroscopy, Raman Spectroscopy, NMR, X-ray Spectroscopy, and Electron Microscopy, and the last section addresses selected polymer processing techniques such as moulding, casting, extrusion, coatings, and foaming.
Loose-Leaf Version for What Is Life? a Guide to Biology with Physiology, Updated
Ichnology of the Permian-Triassic Mass Extinction in China
Dynamics of Bacteria-Mucus Interactions
This volume details the importance of bacteria in and around the human body, highlighting the bacteria that is harmless and pathogenic bacteria. Chapters guide readers through protocols on different bacteria's providing a better understand on they operate and how people can protect ourselves. Written in the highly successful Methods in Molecular Biology series format, the chapters include brief introductions to the material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlights tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Dynamics of Bacteria-Mucus Interactions aims to be comprehensive guide for researchers in the field.
Resilient Forest Management
Global forest management is now grappling with ways to address the many dimensions of global change, including a warming climate and increasing forest disturbance from fires and pest outbreaks, along with changes in public values. However, the dominant forest management paradigms still assume a constant and predictable world in which command-and-control (i.e., treating long-lived forests much like short-lived agricultural crops) and single-value (i.e., timber) optimization still prevail. This novel text argues for new approaches to forest management that focus on resilience and embracing adaptability to the changing socio-ecological environment as it unfolds. Resilience is the ability of a system to maintain its essential attributes (in the form of composition, structure, and/or function) in response to stress, disruption, or disturbance. Managing a system for resilience places an emphasis on persistence rather than growth, efficiency, or profitability, which can be fulfilled by enhancing the capacity to resist change (i.e., robustness) or by enhancing the capacity to incorporate change in desirable directions (i.e., flexibility), or a combination of the two. Resilient Forest Management develops many of the same resilience-enhancing strategies for protected areas, multi-purpose forests, and timber production lands, but with different degrees of emphasis. Featured prominently are practices that enhance diversity, connectivity in space and time, and adaptive management as informed by vulnerability analysis and broad stakeholder consultation. In so doing, Resilient Forest Management builds on foundational concepts of ecological forestry and our understanding of complex adaptive systems and takes sustainable forest management to the next level. Resilient Forest Management will be suitable as a primary or supplementary text in forest policy and management. It will appeal to graduate-level students and researchers in the fields of forestry and conservation along with active policymakers in government, the forest industry, and environmental non-governmental organizations. While focused on forestry, parks managers, agriculturists, and urban planners too will find much useful insight and many creative solutions to sustainable development in a changing world.
A Thousand Years Before Darwin
This enlightening book explores the significant yet often overlooked contributions of Muslim scholars to the fields of biology and anatomy, revealing a rich and pioneering legacy from the Islamic Golden Age. It challenges the widespread belief that major scientific breakthroughs were solely the domain of Western thinkers, shedding light on the advanced anatomical knowledge developed by Arabic and Persian scholars long before Vesalius.The authors trace how Muslim physicians and scientists meticulously studied human and animal anatomy, conducted dissections, and recorded their findings with remarkable accuracy. Their work laid essential foundations for later developments in Europe, yet remains largely ignored in mainstream accounts of scientific history.This book exposes how dominant historical narratives have sidelined the achievements of non-Western scholars-particularly those from the Muslim world-due to cultural bias and colonial influence. Through compelling analysis and accessible storytelling, it calls for a reassessment of the global roots of modern science and encourages a more inclusive and accurate understanding of our shared intellectual heritage.Rather than simply offering a revisionist history, this work serves as a call to action. It urges historians, educators, and scientists alike to recognize the interconnectedness of human knowledge and to celebrate the diverse cultures that have shaped the scientific world we know today. The authors advocate for further comparative research and a deeper appreciation of the intellectual contributions that flourished outside of Europe-contributions that were often obscured or forgotten in the shaping of Western-centric historical accounts.This is an essential read for anyone interested in the history of science, the role of culture in shaping intellectual traditions, and the rich contributions of Muslim scholars to biology, anatomy, and the broader scientific endeavour. It challenges us to rethink what we know about the origins of science-and to honour the global spirit of inquiry that defines the human quest for knowledge.
Resilient Forest Management
Global forest management is now grappling with ways to address the many dimensions of global change, including a warming climate and increasing forest disturbance from fires and pest outbreaks, along with changes in public values. However, the dominant forest management paradigms still assume a constant and predictable world in which command-and-control (i.e., treating long-lived forests much like short-lived agricultural crops) and single-value (i.e., timber) optimization still prevail. This novel text argues for new approaches to forest management that focus on resilience and embracing adaptability to the changing socio-ecological environment as it unfolds. Resilience is the ability of a system to maintain its essential attributes (in the form of composition, structure, and/or function) in response to stress, disruption, or disturbance. Managing a system for resilience places an emphasis on persistence rather than growth, efficiency, or profitability, which can be fulfilled by enhancing the capacity to resist change (i.e., robustness) or by enhancing the capacity to incorporate change in desirable directions (i.e., flexibility), or a combination of the two. Resilient Forest Management develops many of the same resilience-enhancing strategies for protected areas, multi-purpose forests, and timber production lands, but with different degrees of emphasis. Featured prominently are practices that enhance diversity, connectivity in space and time, and adaptive management as informed by vulnerability analysis and broad stakeholder consultation. In so doing, Resilient Forest Management builds on foundational concepts of ecological forestry and our understanding of complex adaptive systems and takes sustainable forest management to the next level. Resilient Forest Management will be suitable as a primary or supplementary text in forest policy and management. It will appeal to graduate-level students and researchers in the fields of forestry and conservation along with active policymakers in government, the forest industry, and environmental non-governmental organizations. While focused on forestry, parks managers, agriculturists, and urban planners too will find much useful insight and many creative solutions to sustainable development in a changing world.
Porous Metals
This reprint is a collection of 10 papers from a Special Issue on porous metals in the journal Materials. These papers involve several manufacturing technologies, including 3D printing, melt infiltration, and powder sintering. They cover a range of different materials, including titanium, aluminum, copper, magnesium alloys, composites, and sandwich structures. They investigate a range of properties that are either uniquely derived from porous structures or heavily influenced by porous structures, including mechanical properties, energy absorption in explosions, friction, the capillary effect, the heat transfer coefficient, and catalytic efficiency. This collection introduces the most recent advances in the field of porous metals and captures the diverse and comprehensive nature of different facets of porous metals, with special emphasis on new fabrication methods, novel structures, new properties, and new applications. It is a useful reference for researchers and practitioners alike in the field.
Drug Carriers Production Processes for Innovative Human Applications
This collection of papers describes recent advances in drug delivery systems, with a focus on nanocarriers, controlled release mechanisms, and their biomedical applications. The selected contributions explore a wide range of strategies for improving the therapeutic efficacy and targeting of pharmaceutical compounds through innovative formulation approaches. Strong emphasis is placed on the development of transdermal patches, hydrogels, liposome-based carriers, nanoemulsions, and functionalized nanomaterials, all of which have been designed to optimize drug release profiles and enhance pharmacokinetics. Antibacterial and anticancer applications are particularly well represented, reflecting the current challenges in both infectious disease treatment and oncology. By integrating engineering, pharmaceutical science, and medical research, this collection offers a comprehensive overview of modern approaches to drug delivery and their potential for clinical translation. Furthermore, these works highlight the growing relevance of biocompatible and sustainable materials, along with mathematical modeling for release kinetics, in shaping the future of therapeutic technologies.
Environmental and Occupational Exposure to Chemical Agents and Health Challenges
This Special Issue focuses on the use of biomonitoring tools applied to human environmental and occupational chemical exposures, and on the toxicological characterization and modes of action of hazardous and its possible health effects. A better knowledge and understanding of toxicological aspects and respective effects at a molecular and cellular level, in parallel with the development and application of biomonitoring tools in exposome science, enables science-based decisions at regulatory toxicology.
Salmonella and Salmonellosis
This Special Issue compiles studies on the impact of Salmonella on animal and public health, focusing on its presence throughout the food chain, from farm to fork. It includes eleven studies from authors across six countries, highlighting the global zoonotic threat posed by Salmonella and its contribution to public health risks. The research covers innovative strategies for controlling this pathogen, such as the use of bacteriophages, essential oils, and vaccines, with an emphasis on One Health approaches. It also highlights antimicrobial resistance, particularly in serotypes like S. Enteritidis and S. Typhimurium, which exhibit growing issues of multidrug resistance. Additionally, control methods in pork and poultry production, the impact of national Salmonella control programs, and the use of predictive models to improve food safety are explored. This Special Issue underscores the importance of integrated strategies combining pre- and post-harvest measures, promoting biosecurity, vaccination, and environmental management. It also advocates for research into new antimicrobial treatments and the development of sustainable methods to reduce pathogen persistence.
Zebrafish
Zebrafish are an attractive vertebrate model used in drug discovery. Due to their small size, external development, and transparency, zebrafish embryos are compatible with multiwell plates for high-throughput screening. Based on the availability of zebrafish genome sequences, the ease of creating transgenic and genetic mutants, and the conservation of signal transduction pathways, a variety of human diseases have been modeled using zebrafish. Moreover, biological pathways, such as physiological and molecular events, which control the development and function of most organ systems, including the cardiovascular, skeletal, nervous, digestive, and visual systems of zebrafish, are similar to those in mammals. The zebrafish reference genome published in 2013 has further accelerated the use of zebrafish in human disease modeling. Over the last two decades, zebrafish have become popular in pharmaceutical and toxicological research. Consequently, several drugs used to treat human diseases (including tuberculosis, neuronal, and auditory disorders, as well as several types of cancer) have been identified from zebrafish screens. Such advances in this area of research have established zebrafish as an invaluable human disease model. This collection of articles aims to cover current research and provide an overview of the advances made in the area of drug discovery and disease modeling using the zebrafish model.
