Hydro-Economic Models for Sustainable Water Resources Management
The Extraction and Application of Functional Components in Algae
A Better Death
Essential reading on assisted dying, blending ethical debate with practical guidance. Assisted dying is one of contemporary society's most pressing and divisive social issues. Should terminally ill people in pain be allowed to choose death on their own terms? This timely and accessible book lays out the moral, legal, and practical dimensions of the debate. It draws on real-life experiences, explores opposing viewpoints with sensitivity, and examines the wider social and ethical implications. Designed for readers of all beliefs and backgrounds, it presents the facts with clarity and compassion. A pioneering section also offers the first guide to meaningful ceremonies at the time of an assisted death, helping families honor life and ease grief. Whether you support, oppose, or are unsure about assisted dying, this essential book provides insight and guidance on a deeply personal issue.
Exclusive Papers of the Editorial Board Members of the Organic Chemistry Section of Molecules
The Reprint brings together fourteen invited contributions from members of the Editorial Board of the Organic Chemistry Section of Molecules, showcasing the scientific depth, creativity, and methodological diversity that define contemporary organic chemistry. Each manuscript was selected to highlight a frontier of the field-spanning natural product chemistry, synthetic methodology, heterocyclic innovation, photochemical reactivity, reagent design, and biologically active small molecules-and together they form a unified representation of the Section's scientific leadership.
Suicidal Behaviors
This Special Issue aims to deepen the understanding of suicidal behaviors (SBs), as well as their risk and protective factors, and to highlight innovative approaches to intervention, prevention, and postvention. The collected contributions illustrate the multifaceted nature of suicidality, addressing its psychological, social, and contextual dimensions across diverse populations and life stages. Empirical studies examine the impact of various forms of violence on SBs in Mexico, psychopathological networks in individuals with and without suicidal ideation, and the concurrent validity of digital tools for risk assessment. Research focusing on adolescents explores the interplay between regulation strategies, contextual stressors, addictions, and suicidality. Preventive strategies are also considered, including measures targeting high-risk locations, the influence of social bonds within military units, and suicide prevention efforts in older veterans. Additionally, systematic reviews synthesize evidence on grief interventions for suicide loss survivors, the role of social cognition in psychosis, and the mechanisms linking defeat, entrapment, and depression to suicidal ideation in youth. A sociological perspective further situates suicidality within the post-COVID-19 context in Spain. Together, these contributions provide a comprehensive and integrative outlook that enriches our understanding of SBs and informs tailored, evidence-based strategies to reduce their burden.
Journeys in Long-Term Care
Journeys in Long-Term Care...is an illuminating and compassionate answer to one of America's most difficult questions: How can ordinary people actually access and manage long-term care? - Clay Farris, Chief Growth Officer, and Founder of MostlyMedicaidAs many as 7 in 10 older adults will require some level of long-term care, but few individuals understand Medicaid, Medicare, and other resources and how to access the care they need. Journeys in Long-Term Care provides essential resources and insights while illustrating real-world examples of individuals navigating this complex system.Meulemans gives you up to date knowledge from 25 years of experience in Medicaid policy and Medicaid managed care contracting, managed the sale of Medicare health plans, and was a consultant involved in Affordable Care Act implementation. In addition he share the real-life long-term care journeys of three families.In this book, you will learn: the best ways to access various government healthcare programsresources to access Medicare and Medicaid benefits and eligibilityhow to apply for disability benefits under Social Securitycoverage and benefits of long-term care insurancehow to manage both Medicare and Medicaid eligibility and benefits if eligible for bothhow veteran's benefits supplements Medicare and Medicaid coverageEveryone is eventually affected by aging, whether it's yourself or a loved one, so the more you know about resources and programs, the smoother the process will be. Pick up Journey's in Long-Term Care and arm yourself with the best information for you and your loved ones.Journeys in Long-Term Care demystifies one of the most complex systems in American healthcare-and does so with clarity, compassion, and real-world wisdom. Joshua Boynton, Founder of LifeShare
Pharmacology - I
Dive into the intricate world of pharmaceuticals with "Pharmacology - I," a comprehensive guide that bridges the gap between fundamental knowledge and clinical application. With 29 detailed chapters covering everything from drug mechanisms to therapeutic uses, this book is a must-have for pharmacy, medical, and dental students. Filled with diagrams, tables, and the latest advancements in the field, "Pharmacology - I" ensures a captivating and informative read. Whether you're a novice or a seasoned professional, this textbook promise to enhance your understanding of pharmacological principles and rational drug use. Get ready to expand your knowledge and embark on a journey through the cutting-edge realm of pharmacology.
Journeys in Long-Term Care
Journeys in Long-Term Care...is an illuminating and compassionate answer to one of America's most difficult questions: How can ordinary people actually access and manage long-term care? - Clay Farris, Chief Growth Officer, and Founder of MostlyMedicaidAs many as 7 in 10 older adults will require some level of long-term care, but few individuals understand Medicaid, Medicare, and other resources and how to access the care they need. Journeys in Long-Term Care provides essential resources and insights while illustrating real-world examples of individuals navigating this complex system.Meulemans gives you up to date knowledge from 25 years of experience in Medicaid policy and Medicaid managed care contracting, managed the sale of Medicare health plans, and was a consultant involved in Affordable Care Act implementation. In addition he share the real-life long-term care journeys of three families.In this book, you will learn: the best ways to access various government healthcare programsresources to access Medicare and Medicaid benefits and eligibilityhow to apply for disability benefits under Social Securitycoverage and benefits of long-term care insurancehow to manage both Medicare and Medicaid eligibility and benefits if eligible for bothhow veteran's benefits supplements Medicare and Medicaid coverageEveryone is eventually affected by aging, whether it's yourself or a loved one, so the more you know about resources and programs, the smoother the process will be. Pick up Journey's in Long-Term Care and arm yourself with the best information for you and your loved ones.Journeys in Long-Term Care demystifies one of the most complex systems in American healthcare-and does so with clarity, compassion, and real-world wisdom. Joshua Boynton, Founder of LifeShare
Not Science. Not Scientists.
When doctors, virologists, and health organizations make claims, we take them as scientific fact. But what if this is not the case? What if the medicine, as we know it today, is based on false principles?Not Science, Not Scientists exposes how modern medicine and virology have falsely claimed the mantle of science, adopting its language, symbols, and authority while lacking its rigorous foundation. Challenging the popular belief that medical and biological disciplines represent genuine science, analytical chemist/scientist Saeed Qureshi shows how they rely on assumptions, opinions, and statistical manipulation rather than the direct, measurable study of substances. The integrity of true science, he argues, relies on chemistry, physics, and mathematics-the disciplines that deal with matter, energy, and the laws that govern their behaviour. Using laboratory theatrics and complex jargon, medicine and virology have dressed themselves up, distorting terms like "isolation," "virus," and "evidence-based medicine" to justify unscientific practices.Drawing on real-world examples and his decades of experience in analytical chemistry, Dr. Qureshi show us how the misuse of science has misled the public, corrupted medical research, and corroded trust in what was once considered the most objective of disciplines. Ultimately, Not Science, Not Scientists is a call to restore intellectual honesty and scientific integrity to medicine by returning to chemistry-the true and original science-as its foundation. Only by grounding medical practice in genuine chemical understanding can it once again serve truth, reason, and humanity.
Not Science. Not Scientists.
When doctors, virologists, and health organizations make claims, we take them as scientific fact. But what if this is not the case? What if the medicine, as we know it today, is based on false principles?Not Science, Not Scientists exposes how modern medicine and virology have falsely claimed the mantle of science, adopting its language, symbols, and authority while lacking its rigorous foundation. Challenging the popular belief that medical and biological disciplines represent genuine science, analytical chemist/scientist Saeed Qureshi shows how they rely on assumptions, opinions, and statistical manipulation rather than the direct, measurable study of substances. The integrity of true science, he argues, relies on chemistry, physics, and mathematics-the disciplines that deal with matter, energy, and the laws that govern their behaviour. Using laboratory theatrics and complex jargon, medicine and virology have dressed themselves up, distorting terms like "isolation," "virus," and "evidence-based medicine" to justify unscientific practices.Drawing on real-world examples and his decades of experience in analytical chemistry, Dr. Qureshi show us how the misuse of science has misled the public, corrupted medical research, and corroded trust in what was once considered the most objective of disciplines. Ultimately, Not Science, Not Scientists is a call to restore intellectual honesty and scientific integrity to medicine by returning to chemistry-the true and original science-as its foundation. Only by grounding medical practice in genuine chemical understanding can it once again serve truth, reason, and humanity.
Children and Adolescents with Neurodevelopmental Disabilities
This Reprint presents an integrated overview of current research on ecological assessment tools and cognitive analysis in children and adolescents with neurodevelopmental disabilities. The collected works reflect a shift from isolated, component-based cognitive testing toward performance-oriented, context-sensitive approaches that emphasize real-world functioning and participation. Functional cognition is conceptualized as a dynamic interaction between cognitive abilities, task demands, environmental contexts, and strategy use. The contributions demonstrate that traditional decontextualized assessments provide limited insight into everyday functioning and potential for learning.Across the articles, a consistent movement toward top-down assessment models emerges, focusing on meaningful occupations, naturalistic task performance, and daily participation across diverse populations and cognitive domains. A central theme of the Reprint is the growing role of digital and immersive technologies, including virtual reality, mobile platforms, and ecological momentary assessment, in creating controlled yet authentic contexts for functional cognitive evaluation.Overall, this Reprint advances a person-centered, participation-focused perspective and offers a framework for developing ecologically valid, technology-enhanced assessment tools for children and adolescents with neurodevelopmental disabilities.
Natural Products Chemistry
This Special Issue stemmed from the success of the first edition of the collection entitled "Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies", which was published in Molecules in 2023. Modern chemical sciences, and medicinal chemistry in particular, are strongly related to natural products, which represent a challenge for researchers in terms of their extraction, analytical characterization and synthesis. Flavonoids, alkaloids and terpenes are chemical classes that have attracted the interest of medicinal chemists for the identification and development of novel therapeutic solutions.This Special Issue collected original contributions and review articles that describe the extraction, structural elucidation, synthesis and biological evaluation of natural, semisynthetic derivatives and nature-inspired molecules, with a particular focus on compounds of pharmaceutical interest. As a result, between 2024 and 2025, eight articles (including four research articles and four reviews) were published in this Special Issue, highlighting the strong interest of the scientific community in various aspects of the chemistry of natural compounds. Moreover, this volume had international reach, attracting submissions from authors across the globe, with corresponding authors from China, Ecuador, Italy, Japan, Poland, Saudi Arabia, South Africa, and the USA, along with their collaborators from countries such as Egypt, Palestine, and Ukraine.
Updates on Interstitial Lung Disease
Interstitial lung diseases (ILDs) remain among the most challenging conditions in respiratory medicine, marked by clinical heterogeneity, progressive decline, and outcomes that rival advanced malignancy. Over the past decade, advances in diagnostics, therapeutics, and multidisciplinary care have reshaped the landscape, yet substantial unmet needs persist. The 2025 Special Issue on Updates in Interstitial Lung Disease brings together a collection of pragmatic reviews and original research that aim to inform the reader about emerging science and assist with clinical practice. This Special Issue highlights updated perspectives on evolving disease diagnosis and management. It addresses the practical challenges of managing ILD in the real world, with reviews focused on multidisciplinary approaches, comorbidity care, and symptom management. Alongside these reviews, original investigations present novel data on disease mechanisms, clinical phenotypes, and therapeutic strategies. Our goal is to provide clinicians and researchers with an accessible resource that informs daily practice while pointing to the future directions of the field.
Nursing Innovation and Quality Improvement
As the largest profession in healthcare, nurses are fundamental to high-quality care. There is hardly a patient treatment or intervention that has not been, at some point, delivered or supported by a nurse. The Nursing and Midwifery Council Strategy (2020-2025) and the Future of Nursing (2020-2030) highlight the importance of improvement and innovation, with nurses being advocated as innovators and leaders in healthcare and calling on healthcare systems to support nurses in these roles. There has never been a more crucial time to equip nurses with the skills and opportunities to embrace innovation and lead improvements that enhance productivity, improve wellbeing, and positively impact healthcare quality and patient safety. However, creating a culture for innovation and quality improvement (QI) in nursing is not easy; it takes time to develop and requires vision, strategy, support, and resources. Innovators need the space and opportunity to connect with others, brainstorm, discuss, and take risks. Greater engagement of front-line nurses in QI initiatives improves nurse-sensitive indicators; however, the number of nurses involved in QI is still worryingly low. Innovations and improvements led by nurses can make significant contributions to patient care, but the speed of these actions needs to improve if we are to address the global health challenges we face today.
Fibromyalgia
FIBROMYALGIAFibromyalgia afflicts a large percentage of the population, yet medical professionals still understand very little about this condition.While there is no known definitive cause, this book explains and describes some of the factors that are believed to contribute to the development of Fibromyalgia. There is also no known cure for the condition, but there are many treatment methods as described within this book, including medical, alternative, and self-help solutions. This book explains how Fibromyalgia is diagnosed, along with the signs and symptoms that occur as a result of the condition. Fibromyalgia can be very difficult to live with, unless you get a proper diagnosis and treatment. Through reading this book, you'll better understand how to manage, treat, and improve you Fibromyalgia in order to live a happy, pain-free, and normal life! Here Is What You'll Learn About... How Fibromyalgia is Diagnosed Signs & Symptoms of Fibromyalgia Pharmaceutical Treatments for Fibromyalgia Alternative Therapies to Combat Fibromyalgia Self-Help Strategies for Managing Fibromyalgia How to Live a Happy Life in Spite of Fibromyalgia Much, Much More!
Marine Natural Products as Anticancer Agents 3.0
Despite advances in cancer biology and therapeutic strategies in recent decades, cancer remains a huge threat to human health and one of the deadliest diseases worldwide. Therapy failure and consequent cancer relapse are the main factors contributing to high cancer mortality. Accordingly, it is crucial to discover and develop new therapeutic options, including innovative and targeted drugs. Marine natural products reveal unique and rare chemical features not found in terrestrial environments. Such unique scaffolds can inspire the molecular modeling and chemical synthesis of novel anticancer drugs. As these compounds were produced in coevolution with biological systems, they present greater efficiency and specificity for interacting with biological target sites (e.g., receptors, DNA, and proteins). These compounds also exhibit novel mechanisms of action, the ability to modulate distinct intracellular signaling pathways, and present fewer side effects. International regulatory authorities have already approved several marine molecules for treating distinct types of cancer.This Special Issue highlights the potential of marine natural products as anticancer agents, empathizing with the diversity of the molecular targets and the mechanistic effects.
Molecular Advances in Dry Eye Syndrome
This Reprint, "Molecular Advances in Dry Eye Syndrome", presents a collection of recent studies that explore the biological, biochemical, and immunological mechanisms underlying dry eye disease. This Reprint highlights the latest progress in lipidomics, extracellular vesicle biology, neurosensory regulation, and immune dysregulation, as well as emerging pharmacological and biological therapies. Together, these contributions provide an integrated molecular perspective on disease pathophysiology, identify novel biomarkers and therapeutic targets, and outline strategies for more personalized diagnostic and treatment approaches. The Reprint offers researchers and clinicians an updated and comprehensive overview of current scientific advances shaping the future of dry eye disease management.
Influence of Natural and/or Vaccine Immunity on the Dynamics of SARS-CoV-2
This Special Issue, "Influence of Natural and/or Vaccine Immunity on the Dynamics of SARS-CoV-2", published in Vaccines, examines how immunity acquired through natural infection, vaccination, or both shapes SARS-CoV-2 transmission, reinfection, variant spread, and pandemic dynamics. Hosted in the Epidemiology and Vaccination section, it provides a multidisciplinary forum to advance understanding of immune protection in an evolving pandemic. It emphasizes that SARS-CoV-2 immunity is dynamic rather than binary, influenced by factors such as prior exposure, vaccine type and dosing, immune waning, viral variants, hybrid immunity, and host characteristics. The emergence of immune-evasive variants, particularly within the Omicron lineage, highlights the need to clarify how different forms of immunity affect clinical outcomes and population-level patterns. Contributions address mechanisms of humoral and cellular immunity, comparisons between natural, vaccine-induced, and hybrid immunity, variant-specific immune escape, reinfection and vaccine effectiveness, host factors modifying immune responses, and modeling studies linking immunity to transmission and public health policy. Article types include original research, reviews, short communications, and editorials, all peer reviewed. The Special Issue underscores the importance of integrating immunological, clinical, and epidemiological evidence to inform vaccine strategies and public health decision making.
Pediatric Intensive Care
Pediatric Intensive Care Units (PICUs) are highly specialized medical facilities dedicated to managing both conditions that are unique to children and others that are also encountered in adults but require a distinct, age-related therapeutic approach. This reprint originates from a comprehensive call for contributions on "Pediatric Intensive Care-Practice and Research". The result is a robust collection of papers reflecting the specialty's entire professional and scientific scope, including resuscitation, congenital malformations, acquired infections, and long-term psychological outcomes. By addressing emerging infections, the implications of the global pandemic, and advanced organ replacement therapies, it powerfully highlights contemporary challenges in a field that has long since outgrown its own "infancy".
Synthetic Studies of Marine Bioactive Natural Products and Analogs to Develop Novel Drug Leads
Marine natural products are considered promising sources of drug candidates, especially in the field of anticancer drugs or antibiotics. However, the scarce supply of compounds from natural sources often limits further drug development, and consequently, efficient total synthesis of marine natural products and their derivatives can overcome this drawback. In addition, the synthesis of truncated analogs based on structure-activity relationship (SAR) studies would facilitate the discovery of more accessible drug lead compounds with improved bioactive specificity or ADMET profiles. This Special Issue gathers eight publications, including two reviews and six research articles, focusing on the synthetic study of bioactive marine natural products and their truncated analogs. We hope that many readers will find interest in the contents of this Special Issue, and that it will offer some perspectives for the future development of novel marine-natural-product-derived drug leads for intractable diseases.
Your Tongue Is Talking
YOUR TONGUE HAS A STORY TO TELLWhat if one of the smallest organs in your body held the most significant clues about your overall health? Your Tongue Is Talking introduces Systemic Tongue Mapping (STM), a simple yet powerful tool that reveals how oral health reflects and influences whole-body wellness. While not a diagnostic tool, STM acts as a guide to help patients and clinicians alike recognize early warning signs, connect the dots between oral and systemic conditions, and spark conversations that lead to better health outcomes.Through real case studies and practical insights, this book empowers readers to: See the tongue as a window into systemic healthAsk better questions during healthcare visitsBecome proactive advocates for their own well-beingYour tongue may whisper before your body shouts. Learn how to listen.
Your Tongue Is Talking
What if one of the smallest organs in your body held the most significant clues about your overall health? Your Tongue Is Talking introduces Systemic Tongue Mapping (STM), a simple yet powerful tool that reveals how oral health reflects and influences whole-body wellness. While not a diagnostic tool, STM acts as a guide to help patients and clinicians alike recognize early warning signs, connect the dots between oral and systemic conditions, and spark conversations that lead to better health outcomes.Through real case studies and practical insights, this book empowers readers to: See the tongue as a window into systemic healthAsk better questions during healthcare visitsBecome proactive advocates for their own well-beingYour tongue may whisper before your body shouts. Learn how to listen.
Urologic Cancer
Recent advances in robot-assisted urologic surgery have significantly improved the quality of life for patients with prostate, bladder, and kidney cancers by enabling less-invasive procedures, reducing blood loss, and preserving functional outcomes. These developments may also influence diagnostic value; however, their overall impact remains insufficiently evaluated due to limited data and short follow-up periods. This Special Issue features state-of-the-art studies not only on robot-assisted urologic surgery but also on laparoscopic and transurethral approaches. It will undoubtedly be of great interest to all urologists.
Recent Advances in Microneedle-Mediated Drug Delivery
This Special Issue, titled "Recent Advances in Microneedle-Mediated Drug Delivery," published in Pharmaceutics, presents state-of-the-art research focused on novel developments and biomedical applications of microneedle technologies. The collection highlights innovative approaches across various microneedle types, including dissolving, solid, hollow, and coated microneedles. The key advancements explored in this issue include breakthroughs in microneedle fabrication techniques, materials science, drug encapsulation methods, and controlled release systems. Significant emphasis is placed on demonstrating improved therapeutic outcomes, enhanced bioavailability, and reduced side effects via minimally invasive transdermal delivery. Additionally, applications covering vaccine delivery, biologics administration, and precision medicine illustrate the broad therapeutic scope and clinical relevance of microneedle platforms. Overall, this compilation provides comprehensive insights into recent scientific progress, emphasizes critical future directions, and reinforces microneedle-mediated drug delivery as a transformative approach in pharmaceutical sciences and healthcare innovation.
Cholesterol Explained
Cholesterol Explained offers clear, compassionate, and science-based guidance to help readers understand cholesterol, interpret test results, and navigate treatment options - from medications to lifestyle changes - in a simple yet accurate way. Written by two leading Australian cardiologists, it dispels myths, clarifies controversies, and presents evidence in a practical, accessible style to support confident, personalised decision-making. Whether newly diagnosed, managing long-term risk, or seeking a deeper understanding of heart health, this grounded resource emphasizes precision, evidence-aligned care for every individual.About the Author - Dr Warrick BishopDr Warrick Bishop is a practising cardiologist, best-selling author and keynote speaker, whose 'why' is to help people live as well as possible for as long as possible.He has a special interest in preventing heart attacks by using cardiac CT imaging, managing cholesterol, and paying attention to diet. He also supports patients through education as he believes that the best-educated patients receive the best healthcare. He enjoys a strong social media presence.Dr Bishop is the author of the books Know Your Real Risk of Heart Attack, Have You Planned Your Heart Attack?, Atrial Fibrillation Explained, Cardiac Failure Explained, Cardiac Rehabilitation Explained, and 10 Commandments of Heart Health Explained. He is also the founder and CEO of the Healthy Heart Network.About the Author - Dr Karam KostnerDr Karam Kostner is one of the most experienced lipidologists in Australia. He is an Associate Professor of Medicine at the University of Queensland and Director of Cardiology at Mater Public and Private Hospitals in Brisbane.He is also a director of Cholesterol Care Australia, a specialist cholesterol clinic and research facility in Brisbane, and a senior cardiologist with Heart of Australia, which delivers specialist healthcare services and testing to rural, remote, and indigenous communities across Queensland.His current clinical interests are preventive cardiology and lipid disorders. His passion combines helping people with high cholesterol and investigating new therapies.
Cancer InsideOut
"A three-time cancer survivor and caregiver offers the ultimate guide for supporting someone through cancer. Combining real chemotherapy journal entries with cancer etiquette guidance and 50+ practical support ideas, Cancer InsideOut equips friends and family to make a real difference. "Discover the Unseen Journey of Cancer & Learn to Support Those That Face It.When someone we care about is diagnosed with cancer, especially when chemotherapy is involved, we often want to help but struggle with knowing what to do or say. Cancer InsideOut addresses the question many supporters quietly ask: how can I truly be helpful without making things harder? This book is written for friends, family members, coworkers, and community members who want to offer meaningful, respectful support during cancer treatment. It is organized into three complementary parts.Part One offers selected journal entries from the author's chemotherapy experience, providing a grounded, day-to-day perspective on what treatment can feel like physically, emotionally, and socially. These reflections are included to deepen understanding rather than to center the story on memoir.Part Two provides clear, practical guidance on what to say and what not to say, how to show up in supportive ways, how to respect boundaries, and how to remain present over the long arc of treatment.Part Three presents more than fifty concrete and adaptable ways to help, ranging from small everyday gestures to coordinated forms of assistance that match changing needs and energy levels.Together, these sections offer a thoughtful and usable guide for anyone who wants to move beyond good intentions and provide support that genuinely helps.
Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
Type 2 diabetes, the most prevalent form of diabetes associated with obesity, remains one of the leading global causes of mortality and disability. Type 2 diabetes is usually clustered with other risk factors associated with metabolic syndrome, such as hypertension and hypercholesterolemia. The central pathophysiological condition connecting these diseases is insulin resistance associated with visceral obesity. Insulin resistance alters systemic lipid metabolism and leads to the development of a characteristic form of dyslipidemia, with high levels of plasma triglycerides, low levels of high-density lipoprotein, and predominance of small, dense low-density lipoprotein. Hypertension is one of the most prevalent chronic conditions worldwide, affecting more than one billion adults and representing a leading risk factor for cardiovascular disease. However, many individuals with hypertension remain undiagnosed, untreated, or inadequately controlled. Strict management of blood pressure, along with optimization of serum lipid levels, body weight, and lifestyle factors such as smoking cessation, is crucial for controlling the global burden of cardiovascular disease and reducing the risk of premature mortality. Although recent trends indicate a decline in all-cause and cardiovascular mortality, the risk remains high, particularly among patients with diabetes. In this context, this Special Issue brings together the latest research and advancements contributing to the understanding and management of hypertension, hypercholesterolemia, and type 2 diabetes.