Engineering and Characterisation of Novel Nanomedicine Formulations, 2nd Edition
Advanced Clinical Technologies in Treating Neurosurgical Diseases
Epidemiology, Virulence Factors and Antimicrobial Resistance in Staphylococcus aureus
Mitochondrial Metabolism Alterations in Health and Disease
Mitochondria are key organelles responsible for cell energy production, and they are essential for eukaryotic life. They take part in critical metabolic pathways and are fully integrated into intracellular signaling networks, cellular differentiation, and apoptosis. Mitochondrial functions extend beyond cell boundaries and influence the organisms' physiology by regulating the communication between cells and tissues. Mitochondria are involved in a range of conditions, including inherited mitochondrial disorders, neurodegenerative diseases, dystrophies, heart failure, cardiac dysfunction, vascular diseases and atherosclerosis, pulmonary and respiratory disorders, renal diseases, metabolic disorders, diabetes, aging, and cancer. Therefore, they are attracting increasing attention with the aim of fully understanding the link between the mitochondrial metabolism and the dysregulation of many cellular processes.
Hospital & Clinical Pharmacy for Diploma
Hospital and Clinical Pharmacy is a perfect guide for D. Pharm [E.R 2020] students aspiring to have a flourishing career in pharmacy. This book is designed as per the latest syllabus and covers a wide range of topics in the field of pharmacy. With its 18 chapters the book covers a variety of subjects such as Hospital Pharmacy Hospital Committees Hospital Formulary Supply Chain and Inventory Control Management of Central Drug Store and Storage of Drugs Drug Distribution Compounding in Hospitals Radio Pharmaceuticals Application of Computers in Hospital Pharmacy Practice Clinical Pharmacy Pharmaceutical Care Medication Therapy Management and Home Medication Review Laboratory Tests Drug Information Center Poison Information Centre Pharmacovigilance Medication Errors and Drug Interactions. This book is written in an easy-to-understand language and includes model questions at the end of each chapter making it an ideal book for students preparing for their exams. Every chapter is neatly explained with sub-headings listed in the content s pages helping readers to locate the topic they want to read effortlessly. Hospital and Clinical Pharmacy holds significant importance in the pharmacy sector and this book covers all the essential topics needed to excel in this field. Whether you are a student or a professional pharmacist this book will enrich your knowledge and expand your understanding of the subject. Get your hands on this book today and embark on a journey towards a successful pharmacy career.
Recent Advances in Therapeutic Strategies for the Treatment of Pediatric Diseases
The eight publications in this Special Issue focus on advancing therapeutic strategies specifically tailored to pediatric patients. Despite addressing a wide range of conditions (including fungal infections, cancer, spinal muscular atrophy, sleep-disordered breathing, and drug-induced cardiotoxicity), they share a common goal: to improve the safety, efficacy, and personalization of pediatric therapies. Several studies highlight the importance of appropriate dosing, formulation stability, and bioavailability (e.g., fluconazole, AmBisome(R), and temozolomide), emphasizing the challenges of adapting adult medications for children and the need for age-specific drug testing to minimize the risks associated with off-label prescribing. Gene therapy and precision medicine also emerge as key themes, showcasing innovative therapeutic approaches. Finally, the Special Issue reflects a clear shift toward patient-centered care, promoting safer drug delivery, improved monitoring (e.g., through cardiotoxicity biomarkers), and more evidence-based treatment protocols for children. Collectively, these studies underscore the critical need to design and validate pediatric therapies based on the unique physiological and developmental characteristics of this population.
Where Are We Now and Where Is Cell Therapy Headed?
This collection, titled "Where Are We Now and Where Is Cell Therapy Headed?", brings together original research and reviews that reflect the evolving landscape in cell therapy. It explores how traditional cell-based interventions are being redefined through advances in bioengineering, genome editing, and next-generation immunotherapies, including CAR-T and CAR-NK cells. The collection also examines the rise of cell-free approaches, such as the use of extracellular vesicles and secretomes.Key topics include the pivotal transition from autologous to allogeneic "off-the-shelf" products, strategies to improve standardization and scalability, and the integration of cell therapies with immunomodulatory agents. The contributions highlight cutting-edge applications in oncology, musculoskeletal repair, burn treatment, and retinal degeneration. This Reprint emphasizes the complementary roles of cellular and acellular therapies and the emerging view of cells as modular delivery platforms rather than simply structural components.By addressing both scientific advances and translational hurdles, this collection provides a timely and essential overview of where the field stands today and the challenges that lie ahead.
Dualistic Equilibrium in Neurotransmission and Beyond
How does the brain keep its chemical yin-yang balanced, and what happens when that homeostasis slips? This Reprint distills the Special Issue "Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders" into a thematic tour of modern neurobiology. The opening editorial reframes depression, dementia and allied syndromes as failures of the excitation-inhibition handshake that spans synapse, glia, gut, and immune system. Eight peer-reviewed contributions then act as case studies of these balancing acts: resveratrol soft-modulates monoamine oxidase A; trace amine-associated receptors emerge as fast-acting antidepressant switches; cannabinoid-serotonin crosstalk times stress analgesia; orexin calibrates vigilance; developmental serotonin steers the gut-brain axis; network models expose schizophrenia symptom clusters; miR-200b-3p dampens neuroinflammation in ADHD; and plasma phospho-tau 217-231 forecasts cognitive decline. Each article pairs mechanistic depth with a translational horizon, from structure-guided drug design to multiplex biomarker panels ready for point-of-care testing. The collection also spotlights ethical dosing, sex-specific responses, and digital phenotyping, underscoring a precision-medicine future that treats circuits, not just chemicals. By weaving together pharmacology, multi-omics imaging, and patient-centric analytics, this Reprint offers a convergent neuropsychiatry roadmap that remains timely and actionable even after the submission portal has closed.
Thrive with Osteoporosis
Ayurveda for Her: A Gentle Guide to Hormonal Balance, Digestive Health, and Lasting VitalityFind your natural rhythm. Nourish your hormones. Embrace vibrant health-without the overwhelm.If you've ever felt exhausted by one-size-fits-all health advice, struggled to balance your hormones, soothe digestion, or calm stress in a sustainable way, this book offers a compassionate, practical alternative.Ayurveda for Her is written specifically for women navigating the realities of modern life. Whether you're experiencing PMS, fatigue, bloating, or the transitions of menopause, this accessible guide shows you how to create lasting wellness using the timeless wisdom of Ayurveda adapted for today's routines.Inside, you will discover: The core Ayurvedic principles every woman should knowA healing roadmap for 30 days of digestive and hormonal renewalNourishing, dosha-friendly recipes, from golden milk to khichari and balancing teasSimple self-care rituals (Dinacharya) that support gut health, skin, and mood in under 10 minutesSafe, effective use of Ayurvedic herbs such as ashwagandha and shatavariBreathwork, journaling, and mindfulness practices for emotional balanceReal-life stories of transformation to inspire and encourage youWhy this book is different: Clear, jargon-free guidance that makes Ayurveda approachable for beginnersGentle, sustainable practices designed to fit into busy schedulesFlexible strategies suitable for women in every stage of life-from early adulthood to menopauseA holistic approach that addresses body, mind, and spirit togetherAyurveda for Her offers more than theory-it provides actionable, nurturing practices that are both effective and easy to integrate. No strict rules. No guilt. Just supportive steps that help you feel more grounded, energized, and connected to your body.Even if Ayurveda is new to you, you'll feel guided and empowered to personalize your journey. From simple recipes and daily rituals to emotional self-care, this book encourages progress without pressure and helps you rediscover balance and vitality on your own terms.
Ayurveda for Her
Ayurveda for Her: A Gentle Guide to Hormonal Balance, Digestive Health, and Lasting VitalityFind your natural rhythm. Nourish your hormones. Embrace vibrant health-without the overwhelm.If you've ever felt drained by one-size-fits-all health advice, struggled with hormonal shifts, digestive discomfort, or stress, this book offers a compassionate alternative.Ayurveda for Her is a practical, supportive guide written specifically for women navigating real-life challenges. From PMS and fatigue to bloating and menopause, it blends ancient Ayurvedic wisdom with modern, sustainable routines that fit into busy lives.Inside, you will discover: The core Ayurvedic principles every woman should knowA healing roadmap for 30 days of digestive and hormonal renewalNourishing, dosha-friendly recipes-from golden milk to khichari and balancing teasSimple self-care rituals (Dinacharya) to support gut health, skin, and mood in under 10 minutesSafe, effective use of Ayurvedic herbs such as ashwagandha and shatavariBreathwork, journaling, and mindfulness practices for emotional balanceReal-life stories of women who found renewed energy and calm through AyurvedaWhy this book is different: Clear, jargon-free explanations of Ayurveda made accessible for beginnersGentle, sustainable practices that encourage progress without guilt or rigid rulesFlexible strategies that adapt to every stage of a woman's life-from early adulthood to menopauseA holistic approach that honours body, mind, and spirit equallyAyurveda for Her empowers women to reconnect with their inner wisdom, restore balance, and create simple daily rituals that support long-term health. You do not need to be an expert or adopt strict routines-small, intentional steps can bring profound change.Even if Ayurveda is new to you, this guide offers encouragement and practical tools to personalize your wellness journey. Whether you are seeking to ease symptoms, prevent imbalances, or cultivate greater energy and joy, these pages provide a trusted companion on your path to vitality.
Connections Between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies
State of the Art in Biomaterials for Drug Delivery
Nowadays, biomaterials are widely used in medicine and the medical care fields, playing increasingly important roles due to their unique structure and excellent performance. In particular, biomedical materials exhibit good biocompatibility and biodegradability, which allow for their design in drug delivery to the human body.Biomedical materials as anticancer drug carriers can be implemented in targeted drug delivery in the human body, improve the utilization rate of the cancer drug effects, and largely reduce the side effects of anticancer drugs on normal human body cell tissue. In addition, the drug carrier can also effectively improve the properties and stability of anticancer drugs in tissues, enhance the slow release of drugs, and reduce the lack of drug use in the body. Moreover, advancements in biomaterials have improved the safety and efficacy of diagnostic, therapeutic, and theranostic approaches for various diseases. The structures and interactions between biomaterials and drugs can influence the pesticide effect and have the potential to affect cellular physiology due to the close relationship between biological systems and biomaterial features. Drug delivery systems can also provide novel solutions by developing desirable and ideal materials to control the physicochemical, biological, structural, and mechanical microenvironments for successful drug delivery.This Special Issue focuses on biomaterials, including, but not limited to, natural materials, composite materials, functionalized nanomaterials, hydrogels, etc., for different drug delivery applications.
Fractal and Fractional Analysis in Biomedical Sciences and Engineering
Education and Communication in Veterinary Clinical Practice
Effective communication is a hallmark of successful veterinary clinical practice. Communication underpins professionalism, establishes effective teamwork, and is essential to veterinary-client relationships. Teaching or developing effective communication is an increasingly important component of the 'hidden' curriculum for veterinary educators, introduced and reinforced throughout the teaching program. Effective communication is also a focus for prospective employers when considering a new graduate. Successful communication must also consider the rapidly changing modalities of how people communicate and, importantly, how important communication will be toward resilience in a highly stressful profession. This Special Issue highlights what is effective communication, how this can be 'taught', and its importance toward veterinary clinical practice.
Dietary Habits and Metabolic Health
"Dietary Habits and Metabolic Health" examines the interplay between nutritional practices and metabolic outcomes, focusing on emerging research across diverse dietary factors. Key areas of exploration include the metabolic consequences of altered nutrient profiles in processed foods, such as protein and lipid oxidation products, glycosylation derivatives, and microbial-driven nutrient modifications. It also investigates the role of probiotics and prebiotics in modulating gut microbiota, metabolic pathways, and physiological responses under varying dietary patterns. Additional topics encompass the metabolic effects of dietary practices like energy restriction, single-nutrient limitation, and intermittent fasting, as well as connections between diet, gut microbiota composition, and chronic disease risk. The issue further highlights personalized dietary interventions as a tool for metabolic regulation. By synthesizing evidence from food science, nutrition, and medicine, this Special Issue aims to deepen insights into how dietary behaviors influence metabolic health and inform strategies for disease prevention and management.
Advanced Pharmaceutical Science and Technology in Israel
Israel has a significant and diverse history of ground-breaking research and development in pharmaceutical sciences and technology within academic settings, pharma/biopharma companies, and the biotech community. This Special Issue of Pharmaceutics, entitled "Advanced Pharmaceutical Science and Technology in Israel", was put together to highlight the exceptional achievements and significant international impact of pharmaceutical research performed in Israel in celebration of the country's 75th diamond anniversary of growth and prosperity. Naturally, the articles in this reprint represent only a small fraction of the ground-breaking pharmaceutical research and development taking place in Israel. That being said, this collection of articles does serve as a unique example of the outstanding and diverse contributions Israel has made to the global pharmaceutical arena. The Special Issue covers many hot topics in the pharmaceutical sciences, including gene therapy, cell-based therapy, nanomedicine, new drug delivery systems, 3D printing, space medicine, personalized medicine, and advanced PBPK modeling. We hope that this Special Issue will contribute to multidisciplinary discussions on these exciting topics and prompt new scientific collaborations, further advancing pharmaceutical sciences and engineering in Israel and globally. Looking to the future, Israel will undoubtedly continue to be a significant pioneer in the global pharmaceutical science and technology arenas.
Metabolic Features and Nutritional Interventions in Chronic Diseases
A growing body of research indicates an extensive metabolic dysfunction in a spectrum of chronic diseases, comprising aging, cancer, and diseases affecting the cardiovascular system, liver, and kidneys. The phenotypes associated with metabolic dysfunction vary depending on disease type and stage. In turn, the altered metabolism drives disease pathology. Consequently, the nutritional modulation of metabolic status in chronic disease is widely acknowledged to reduce disease incidence. For instance, tailored nutritional intervention in cancers with altered metabolism determines the improved therapeutic responses. Additionally, counteracting muscle loss and osteoporosis are clinical goals of nutritional support in an aged population. Mechanistically, bioactive nutrients or tailored nutritional regimen modulate metabolism through mitochondrial homeostasis, immuno-regulation, as well as epigenome regulation to impact disease progression. This reprint aims to be an interdisciplinary platform that covers (1) characterization of metabolic features and/or nutritional requirement in a certain type of chronic disease; (2) defining the effects and mechanism of a specific nutrient or nutritional intervention on metabolism; (3) development of new nutritional strategy that improves disease outcome by altering metabolism.
Antimicrobial Activity of Natural Products and Plants Extracts
This reprint includes high-quality studies highlighting the complex antimicrobial potential of products derived from natural sources (NPs). The nine articles published in the Special Issue entitled "Antimicrobial Activity of Natural Products and Plants Extracts, 1st Edition" in the journal Antibiotics present scientific data regarding the ability of selected natural products (essential oils, gemmotherapy extracts, solvent extracts, isolated compounds) to inhibit relevant human and veterinary organisms (reference strains, multidrug resistant strains, ESKAPE Pathogens groups, etc.), as well as against bacterial and fungal strains specific to cereals. Interesting results on synergistic associations with antibiotics are reported as well. Furthermore, these studies offer insights into the NPs' chemical-profile-based standardization and multifaced biological properties-antioxidant, hepatoprotective, and cytotoxic-thus demonstrating the need for multidisciplinary studies.
Morphofunctional Nutritional Assessment in Clinical Practice
The diagnosis of malnutrition is difficult because it does not depend only on weight at a given time, but also on its evolution and the underlying pathological situations. Therefore, the clinical use of body composition measurements is essential for adequate assessment of this malnutrition, especially in the evaluation of muscle mass and function. In this context, nutritional assessment can no longer be based on the determination of classical anthropometric measurements. The concept of morphofunctional nutritional assessment postulates that the diagnosis and monitoring of nutritional status must be carried out using techniques and biomarkers that determine the evaluation of intake, anthropometry, body composition, muscle strength, and function that include techniques such as bioelectrical impedance analysis or nutritional ultrasound, and new biological parameters too. This Special Issue aims to show the implementation of this new concept of nutritional evaluation in the management of patients and in clinical research in nutrition.
Pharmaceutical Stability & Stability Testing
Being foreword by Professor Abubakr O. Nur, University of Khartoum, this book combines the theoretical background of dosage form degradation and stability problems together with practical procedures to perform various types of stability studies. It describes the probable physical changes, the chemical kinetics of degradation reactions that may take place and the microbiological spoilage. It considers the influence of different factors on the stability of pharmaceuticals and their impact on the shelf life with emphasis on the effect of temperature taking in account the concept of the mean kinetic temperature and its calculation. The international regulatory guidelines together with the dosage form requirements and specifications and how to estimate or predict the shelf life with practical examples. This book is a valuable guide to students where they can found model question and answers, researchers and professionals of industrial pharmacy.
![Pharmacopoeia Officinalis [et] Extemporanea](https://cdn.kingstone.com.tw/english/images/product/0886/9781024320886m.webp?Q=cc709 "Pharmacopoeia Officinalis [et] Extemporanea")
