Nanocarriers for Nucleic Acids and Proteins
At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nanocarriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science.From fundamental concepts to cutting-edge applications, this comprehensive volume brings together world-class researchers to provide an in-depth examination of: Design principles and characteristics of various nanocarrier systems Advanced delivery mechanisms for nucleic acids and proteins Breakthrough applications in gene therapy and cancer immunotherapy Critical aspects of translating laboratory success to clinical implementation Featuring detailed coverage of lipid-based, polymer-based, inorganic, and bio-inspired nanocarriers, this essential resource bridges the gap between theoretical understanding and practical application. Whether you are developing new therapeutic approaches, optimizing delivery systems, or exploring the frontiers of nanomedicine, this comprehensive guide provides the insights and frameworks needed to advance your work.
Drug Repurposing
This volume is aimed at explaining how drug repurposing works; to what extent the initial hopes have been realised in finding drugs for neurodegenerative diseases, psychiatric disorders, cancer and diseases caused by parasitic worms. Drug repurposing also has had some success in treating bacterial infections. Multi-drug resistance has emerged as a great challenge in the drug development area. Drug repurposing may help there as well; this has been discussed in the context of TB. Like in many other areas, nano-materials have been helpful in formulating drugs for repurposing.The first chapter points out that [a] drug repurposing heralds the demise of the magic bullet concept of drug actions [b] both partners in a drug-target pair are promiscuous and drug repurposing is a subset of polypharmacology.The last chapter talks of vaccine repurposing. Considerable data now exist which makes a compelling case for including this exciting topic.This book is a fair mix of success stories, a reality check on the status of this approach and challenges ahead in this area.
GMP Audits in Pharmaceutical and Biotechnology Industries
This user-friendly volume presents a basic knowledge on how to perform an audit or inspect a facility and meets all the needs of the audience. It is a key reference source for those training as auditors in organizations that follow FDA, EMA, MHRA, WHO, TGA, PIC/S regulations.
Managing the DoD Pharmacy Benefit in the 21st Century
The Future Of Pharmacy
The future of pharmacy is undergoing a transformative shift driven by rapid advancements in technology, personalized medicine, and evolving patient care models. This book explores how artificial intelligence, automation, genomics, digital therapeutics, and telepharmacy are reshaping the role of pharmacists and the delivery of pharmaceutical care. It provides insights into the integration of data-driven approaches in drug discovery, precision medicine, and chronic disease management. Aimed at pharmacy students, healthcare professionals, and researchers, this book offers a forward-looking perspective on how pharmacists can lead in a future focused on innovation, accessibility, and patient-centered care.
Advancements in Hybrid Excipients for Targeted Drug Delivery
"Advancements in Hybrid Excipients for Targeted Drug Delivery" explores the innovative use of hybrid excipients to enhance the precision, efficiency, and safety of drug delivery systems. Combining the benefits of natural and synthetic materials, these advanced carriers improve drug solubility, stability, and controlled release while enabling targeted delivery to specific tissues or cells. The book highlights recent breakthroughs, formulation strategies, and applications in treating diseases such as cancer, infections, and inflammatory disorders. It serves as a valuable resource for researchers, pharmaceutical scientists, and healthcare professionals involved in drug development and delivery system innovation.
Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology
Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology is a comprehensive book that provides a state-of-the-art overview of computational methods in drug discovery, design, and toxicity prediction. The book covers a wide range of topics in computational techniques and approaches, computer applications in pharmacology and toxicology, and future perspectives on new technologies. The coverage includes molecular modeling, virtual screening, machine learning, and network pharmacology as well as examples of how these methods can be applied to the discovery of new drugs, in the optimization of drug candidates, and the assessment of drug safety and toxicity. It will be a valuable resource for researchers, practitioners, and students in the fields of pharmacology, toxicology, medicinal chemistry, bioinformatics, and systems biology.
Peptide Science
Understand the nature and applications of peptides with this clear and comprehensive guide Peptides are signaling molecules comprised of amino acids which play an important role in modulating certain physiological processes. They have a wide range of applications, particularly with respect to biological studies and therapeutical potentials. The explosive growth of peptide science in recent years and the variety of achievements in peptide drug discovery and related areas have made it an important area of study for new researchers and industry professionals. Peptide Science offers a clear, systematic overview of this burgeoning field and its major applications. Covering the chemistry, the pertinent technologies, and major existing therapies, it provides the tools required to integrate peptide research with virtually any area of research and development. Fully cognizant of the latest technological advances, it's a must-own for anyone looking to understand a vital field of chemistry. Peptide Science readers will also find: Through coverage of peptide hit generation technologies from nature, to various display libraries and to modern computational designs Detailed discussion of therapies for conditions including cancer, diabetes, infectious diseases, and more A section dedicated to key challenges and future directions in peptide therapeutics Peptide Science is ideal for industry professionals and researchers in organic chemistry, peptide science/chemistry, protein chemistry, biochemistry, and pharmaceutical sciences.