Where Are We Now and Where Is Cell Therapy Headed?
This collection, titled "Where Are We Now and Where Is Cell Therapy Headed?", brings together original research and reviews that reflect the evolving landscape in cell therapy. It explores how traditional cell-based interventions are being redefined through advances in bioengineering, genome editing, and next-generation immunotherapies, including CAR-T and CAR-NK cells. The collection also examines the rise of cell-free approaches, such as the use of extracellular vesicles and secretomes.Key topics include the pivotal transition from autologous to allogeneic "off-the-shelf" products, strategies to improve standardization and scalability, and the integration of cell therapies with immunomodulatory agents. The contributions highlight cutting-edge applications in oncology, musculoskeletal repair, burn treatment, and retinal degeneration. This Reprint emphasizes the complementary roles of cellular and acellular therapies and the emerging view of cells as modular delivery platforms rather than simply structural components.By addressing both scientific advances and translational hurdles, this collection provides a timely and essential overview of where the field stands today and the challenges that lie ahead.
Recent Advances in Therapeutic Strategies for the Treatment of Pediatric Diseases
The eight publications in this Special Issue focus on advancing therapeutic strategies specifically tailored to pediatric patients. Despite addressing a wide range of conditions (including fungal infections, cancer, spinal muscular atrophy, sleep-disordered breathing, and drug-induced cardiotoxicity), they share a common goal: to improve the safety, efficacy, and personalization of pediatric therapies. Several studies highlight the importance of appropriate dosing, formulation stability, and bioavailability (e.g., fluconazole, AmBisome(R), and temozolomide), emphasizing the challenges of adapting adult medications for children and the need for age-specific drug testing to minimize the risks associated with off-label prescribing. Gene therapy and precision medicine also emerge as key themes, showcasing innovative therapeutic approaches. Finally, the Special Issue reflects a clear shift toward patient-centered care, promoting safer drug delivery, improved monitoring (e.g., through cardiotoxicity biomarkers), and more evidence-based treatment protocols for children. Collectively, these studies underscore the critical need to design and validate pediatric therapies based on the unique physiological and developmental characteristics of this population.
Dualistic Equilibrium in Neurotransmission and Beyond
How does the brain keep its chemical yin-yang balanced, and what happens when that homeostasis slips? This Reprint distills the Special Issue "Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders" into a thematic tour of modern neurobiology. The opening editorial reframes depression, dementia and allied syndromes as failures of the excitation-inhibition handshake that spans synapse, glia, gut, and immune system. Eight peer-reviewed contributions then act as case studies of these balancing acts: resveratrol soft-modulates monoamine oxidase A; trace amine-associated receptors emerge as fast-acting antidepressant switches; cannabinoid-serotonin crosstalk times stress analgesia; orexin calibrates vigilance; developmental serotonin steers the gut-brain axis; network models expose schizophrenia symptom clusters; miR-200b-3p dampens neuroinflammation in ADHD; and plasma phospho-tau 217-231 forecasts cognitive decline. Each article pairs mechanistic depth with a translational horizon, from structure-guided drug design to multiplex biomarker panels ready for point-of-care testing. The collection also spotlights ethical dosing, sex-specific responses, and digital phenotyping, underscoring a precision-medicine future that treats circuits, not just chemicals. By weaving together pharmacology, multi-omics imaging, and patient-centric analytics, this Reprint offers a convergent neuropsychiatry roadmap that remains timely and actionable even after the submission portal has closed.
Thrive with Osteoporosis
Ayurveda for Her: A Gentle Guide to Hormonal Balance, Digestive Health, and Lasting VitalityFind your natural rhythm. Nourish your hormones. Embrace vibrant health-without the overwhelm.If you've ever felt exhausted by one-size-fits-all health advice, struggled to balance your hormones, soothe digestion, or calm stress in a sustainable way, this book offers a compassionate, practical alternative.Ayurveda for Her is written specifically for women navigating the realities of modern life. Whether you're experiencing PMS, fatigue, bloating, or the transitions of menopause, this accessible guide shows you how to create lasting wellness using the timeless wisdom of Ayurveda adapted for today's routines.Inside, you will discover: The core Ayurvedic principles every woman should knowA healing roadmap for 30 days of digestive and hormonal renewalNourishing, dosha-friendly recipes, from golden milk to khichari and balancing teasSimple self-care rituals (Dinacharya) that support gut health, skin, and mood in under 10 minutesSafe, effective use of Ayurvedic herbs such as ashwagandha and shatavariBreathwork, journaling, and mindfulness practices for emotional balanceReal-life stories of transformation to inspire and encourage youWhy this book is different: Clear, jargon-free guidance that makes Ayurveda approachable for beginnersGentle, sustainable practices designed to fit into busy schedulesFlexible strategies suitable for women in every stage of life-from early adulthood to menopauseA holistic approach that addresses body, mind, and spirit togetherAyurveda for Her offers more than theory-it provides actionable, nurturing practices that are both effective and easy to integrate. No strict rules. No guilt. Just supportive steps that help you feel more grounded, energized, and connected to your body.Even if Ayurveda is new to you, you'll feel guided and empowered to personalize your journey. From simple recipes and daily rituals to emotional self-care, this book encourages progress without pressure and helps you rediscover balance and vitality on your own terms.
Ayurveda for Her
Ayurveda for Her: A Gentle Guide to Hormonal Balance, Digestive Health, and Lasting VitalityFind your natural rhythm. Nourish your hormones. Embrace vibrant health-without the overwhelm.If you've ever felt drained by one-size-fits-all health advice, struggled with hormonal shifts, digestive discomfort, or stress, this book offers a compassionate alternative.Ayurveda for Her is a practical, supportive guide written specifically for women navigating real-life challenges. From PMS and fatigue to bloating and menopause, it blends ancient Ayurvedic wisdom with modern, sustainable routines that fit into busy lives.Inside, you will discover: The core Ayurvedic principles every woman should knowA healing roadmap for 30 days of digestive and hormonal renewalNourishing, dosha-friendly recipes-from golden milk to khichari and balancing teasSimple self-care rituals (Dinacharya) to support gut health, skin, and mood in under 10 minutesSafe, effective use of Ayurvedic herbs such as ashwagandha and shatavariBreathwork, journaling, and mindfulness practices for emotional balanceReal-life stories of women who found renewed energy and calm through AyurvedaWhy this book is different: Clear, jargon-free explanations of Ayurveda made accessible for beginnersGentle, sustainable practices that encourage progress without guilt or rigid rulesFlexible strategies that adapt to every stage of a woman's life-from early adulthood to menopauseA holistic approach that honours body, mind, and spirit equallyAyurveda for Her empowers women to reconnect with their inner wisdom, restore balance, and create simple daily rituals that support long-term health. You do not need to be an expert or adopt strict routines-small, intentional steps can bring profound change.Even if Ayurveda is new to you, this guide offers encouragement and practical tools to personalize your wellness journey. Whether you are seeking to ease symptoms, prevent imbalances, or cultivate greater energy and joy, these pages provide a trusted companion on your path to vitality.
Bayesianism
When we speak of Bayesianism, we are referring to a philosophical and statistical framework that involves the representation of degrees of belief or justification using probabilities. It is characterized by the idea that belief comes in degrees that can be formalized using the axioms of probability theory. Bayesianism involves the assessment of the rationality of degrees of belief based on a set of rules and specifies how these beliefs can be updated using Bayes' theorem based on new information or evidence.Many statistics textbooks treat frequentist statistics as the main subject and relegate Bayesian statistics to a single chapter, often near the end of the book. The idea of this Special Issue of Entropy has been to treat Bayesian statistics as the main topic and to provide a snapshot of how Bayesian inference is understood and how it contributes to scientific endeavor today, late in the first quarter of the 21st Century.
Molecules at Play in Neurological Diseases
This Reprint, "Molecules at Play in Neurological Diseases", is compilation of eight articles and an editorial presenting recent research into the roles of specific molecules in the etiology and progression of neurological diseases.
Dendrimers
This Special Issue Reprint is in honor of the creator of dendrimers, Prof. Donald A. Tomalia, on the occasion of his 85th birthday. Prof. Tomalia played a key role in establishing the place of dendrimers in polymer chemistry and in nanosciences. This Reprint displays the recent advances in the field of dendrimers and dendritic structures, with emphasis on diverse biological and pharmaceutical properties, written by many of the major contributors to the field. The first paper, a review, is a reflection on the beginning, past, present, and future of dendrimers in pharmaceutic, medicine, and life science. It is followed by three other reviews about ferrocene-based dendritic drugs inducing the Fenton mechanism to kill cancer cells, dendrimers functionalized with boron clusters for boron neutron capture therapy (BNCT) against cancers, and dendrimers used in vivo as drug carriers. Six research papers describe different types of dendritic structures, such as a large library of amphiphilic Janus dendrimers for the targeted delivery of mRNA and storage of vaccines, dendrons equipped with doxorubicin and an antibody against cancer cells, dendrons forming micelles encapsulating either doxorubicin or different drugs against cancer cells, dendrons cross-linked with polymers to form hydrogels suitable for drug release, and dendrons associated with human serum albumin. Three research papers concern dendrimers against choroidal neovascularization in eyes, protoporphyrin IX, and paclitaxel loaded in dendrimers against cancer cells.
Hearing Loss
Hearing loss represents one of the most wide-ranging disabilities, affecting more than 5% of the world's population. Different types of hearing loss, including conductive and sensorineural hearing loss, may lead to serious hearing impairments in children and adults. Multiple causes may be involved in the aetiopathogenesis of hearing loss, depending on the different biologic mechanisms, including congenital, autoimmune, and genetic factors. Diagnosis and management continue to be a challenge for hearing disorders such as chronic otitis media, otosclerosis, cholesteatoma, congenital or acquired sensorineural hearing loss, sudden sensorineural or metabolic hearing loss, and otogenic facial palsy. Electrophysiology and neuroscience approaches are needed in order to better elucidate the diagnostic dilemmas in the field of otology and neurotology. Neuroimaging is also welcoming the inclusion of temporal bone and cochlear malformations. In our Reprint, new treatment options will be discussed to improve potential methods of hearing restoration and new surgical approaches and techniques will be described in order to better manage different outer-middle-inner ear pathologies.
Hematological Malignancies
This Reprint invites readers on a journey through the latest breakthroughs in hematological malignancies, curated by leading experts who share pioneering research with a vision to propel the field forward. It offers an opportunity to explore the molecular, genetic, and immunological underpinnings of these cancers, illuminating paths to novel, transformative therapies. Through this, a pathway is paved towards advancing patient outcomes and pursuing cures for devastating diseases.
Connections Between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies
This Reprint highlights the importance of a precocious diagnosis and assessment of the risk profile in patients with various metabolic pathologies and cardiovascular disease, especially heart failure, as well as in specific physiological conditions (pregnant women) and special populations (the Roma population, native Japanese, and people living in developing countries). Special attention should be given to pregnant women with subclinical hypothyroidism or vitamin D deficiency and pre-eclampsia. Further studies are required to determine the effect of specific genetic and environmental factors and lifestyle changes on CV risk profiles in subjects with metabolic disorders to enable targeted interventions for these high-risk populations. Continued research efforts in this area are essential in improving our understanding and refining treatment strategies to optimize patients' outcomes.
Therapeutic Potential of Silver Nanoparticles (AgNPs)
Silver nanoparticles (AgNPs) have gained significant attention in the field of biomedicine, primarily for their antimicrobial properties. However, these versatile nanoparticles are now emerging as multifaceted therapeutic agents capable of being used to address a wide range of diseases. AgNPs exhibit size- and shape-dependent properties, allowing them to be tailored for specific applications. Their high surface-area-to-volume ratio and active surface enable precise control over surface charge and functionalization, further expanding their utility. Additionally, AgNPs possess localized surface plasmonic resonance, which holds promise for photo-assisted therapies.AgNPs can be synthesized through various methods, with chemical reduction synthesis being the most commonly used. However, the utilization of biological methods and the adoption of green chemistry approaches are on the rise, aligning with sustainability objectives.This reprint showcases the utilization of AgNPs for therapeutic purposes, ranging from traditional antibacterial applications to innovative uses.
Bone and Cartilage Conduction
Air conduction is the primary pathway for hearing sounds and is widely utilized in various hearing devices. In contrast, other forms of sound conduction-such as bone and cartilage conduction-have not been as commonly applied. However, recent advancements in device development have expanded the applications of these alternative conduction methods across various fields. This Special Issue addresses the mechanisms and practical uses of these methods.Since 2017, a new hearing device utilizing cartilage conduction has been developed and released in Japan. It has gained rapid popularity and is now recognized as one of the primary types of hearing device. Reflecting this trend, most of the contributions in this Special Issue focus on cartilage conduction and hearing aids, with studies submitted from various institutions in Japan.
Cannabis Grow Guide Book
Cannabis Grow Guide Book: Grow Top-Shelf Weed at Home-Step-by-Step Blueprint for Big Yields, Potent Buds, and Indoor/Outdoor SuccessWant to grow top-shelf cannabis in the comfort of your own home? Whether you're a total beginner or a seasoned cultivator, this complete cannabis grow guide gives you the exact blueprint for success.Inside, you'll learn how to grow potent, high-yielding plants indoors, outdoors, in soil, or with hydroponics. With clear instructions, pro grower tips, and troubleshooting strategies, this book is your ultimate reference for cultivating big harvests and premium-quality buds.What You'll Discover Inside: ✔️ Cannabis 101 - Learn the plant's life cycle, anatomy, and growth essentials.✔️ Choosing Your Grow Style - Indoor vs. outdoor setups, hydroponics, and soil growing.✔️ Essential Grow Equipment - Lights, fans, tents, and tools explained for every budget.✔️ Seeds & Strains - How to pick the best genetics for yield, flavor, and potency.✔️ Vegetative & Flowering Stages - Proven techniques for strong growth and dense buds.✔️ Harvesting Like a Pro - When and how to harvest for maximum potency.✔️ Drying & Curing - Preserve terpenes, flavor, and THC with expert methods.✔️ Troubleshooting Guide - Solve common problems like pests, mold, and nutrient issues.✔️ Advanced Techniques - Training, pruning, lighting hacks, and yield-boosting secrets.✔️ Legal & Sustainable Growing - Tips for compliance and eco-friendly cultivation.Why This Book Stands Out: Complete step-by-step guide from seed to harvest.Covers indoor, outdoor, soil, and hydroponics growing.Packed with pro secrets for boosting potency and yields.Beginner-friendly yet detailed enough for advanced growers.Whether you want to grow a few plants at home or master advanced techniques for huge harvests, this is your go-to cannabis grow bible.Perfect For Readers Searching: cannabis grow guide bookmarijuana grow book for beginnerscannabis grow bible step by stepcannabis growing book indoor outdoormarijuana cultivation book hydroponics soilTake control of your grow. Cultivate potent, flavorful, top-shelf buds at home.Get your copy of Cannabis Grow Guide Book today and start your journey to becoming a master grower!
New Advances in Neurosurgery
Neurosurgery is a rapidly advancing field with many new technological developments and innovations. Image-guided surgery, intraoperative imaging and minimally invasive approaches have improved the safety and precision of surgical procedures. While endovascular methods expand, traditional microsurgery is still vital. Pediatric neurosurgery and TBI care face ongoing challenges, requiring specialized centers. This Issue explores some of the challenges that neurosurgery is facing in recent years. Personalized neurosurgery, integrating AI and tailored strategies, marks the future of the field.
State of the Art in Biomaterials for Drug Delivery
Nowadays, biomaterials are widely used in medicine and the medical care fields, playing increasingly important roles due to their unique structure and excellent performance. In particular, biomedical materials exhibit good biocompatibility and biodegradability, which allow for their design in drug delivery to the human body.Biomedical materials as anticancer drug carriers can be implemented in targeted drug delivery in the human body, improve the utilization rate of the cancer drug effects, and largely reduce the side effects of anticancer drugs on normal human body cell tissue. In addition, the drug carrier can also effectively improve the properties and stability of anticancer drugs in tissues, enhance the slow release of drugs, and reduce the lack of drug use in the body. Moreover, advancements in biomaterials have improved the safety and efficacy of diagnostic, therapeutic, and theranostic approaches for various diseases. The structures and interactions between biomaterials and drugs can influence the pesticide effect and have the potential to affect cellular physiology due to the close relationship between biological systems and biomaterial features. Drug delivery systems can also provide novel solutions by developing desirable and ideal materials to control the physicochemical, biological, structural, and mechanical microenvironments for successful drug delivery.This Special Issue focuses on biomaterials, including, but not limited to, natural materials, composite materials, functionalized nanomaterials, hydrogels, etc., for different drug delivery applications.
A World without Measles and Rubella
Measles and rubella continue to affect children worldwide, even though effective, safe, and inexpensive vaccines have been available for over 50 years. Although measles immunization is estimated to have prevented over 56 million childhood deaths since the year 2000, the residual annual burden of 136,216 measles deaths and 32,000 children born with congenital rubella syndrome is unacceptable. Eliminating measles and rubella worldwide is technically feasible, and every WHO region has set measles and rubella elimination targets. However, without a global target, regions are struggling with achieving and then sustaining measles/rubella elimination. Global measles/rubella-containing vaccination coverage stagnated at around 85% for over a decade before declining to lower levels in many countries during the COVID-19 pandemic. Many planned supplemental immunization activities intended to fill the immunity gaps were postponed or canceled during the pandemic. Additionally, nineteen countries have yet to introduce rubella-containing vaccines despite the overwhelming evidence of disease and economic burden, as well as ethical considerations.
Fractal and Fractional Analysis in Biomedical Sciences and Engineering
Over the past two decades, various signal and image analyses, as well as bioinformatics approaches, have had a significant impact on research in life sciences. Problems arising in medical and biological research depend on a multitude of system parameters, often in a nonlinear way; these problems can often be successfully addressed via the tools of complex system analysis. Fractal and fractional analysis, originally rooted in theoretical developments, has later been recognized as well-suited for analyzing problems that occur in nature. Due to the random multiplicative processes in an organism, influencing growth, differentiation, and function, structures can be described in terms of scaled copies of self-similar entities. Machine learning and artificial intelligence are increasingly being employed in combination with fractional calculus.This Special Issue Reprint offers an overview of state-of-the-art developments in the field of fractal and fractional-based methodologies as applied to the analysis and modeling of biological entities. Eight out of ten articles directly target cutting-edge medical problems. It is highly multidisciplinary and is expected to be of interest to researchers from the health sector, life sciences, and applied mathematics, as well as to readers with different academic or practical backgrounds.
Healing Beyond Pills
Are you burned out by modern life, yet untouched by modern solutions? This transformative guide reveals the forgotten healing arts behind true, lasting relief from chronic stress. Blending Ayurvedic stress management, naturopathy for burnout, and Eastern healing therapies, this book invites you on a soul-deep journey one that goes far beyond surface-level fixes. Through powerful stories, somatic healing practices, breathwork rooted in neurobiology, and ritual medicine for stress, you ll discover how to listen to your body s quiet wisdom, align with your natural rhythms, and reclaim vitality without dependence on pills or quick hacks. This is not just a wellness manual it s a map back to yourself. Perfect for seekers of holistic stress relief, mind body transformation, and those longing for gentler, more grounded ways to heal, this book offers practical tools and profound insights for anyone who has ever felt overwhelmed, disconnected, or depleted. Whether you're new to somatic intelligence healing or looking to deepen your path, these teachings will stay with you long after the last page is turned.
Storytelling in Pharma Marketing
How do you make your message stand out in an industry driven by science and data? The answer lies in storytelling-the most powerful tool in a marketer's arsenal. Storytelling in Pharma Marketing unravels the art and science of crafting narratives that build trust, engage stakeholders, and drive meaningful action. Whether you're communicating with healthcare professionals, patients, caregivers, payers, or investors, this book provides a strategic blueprint to create compelling, ethical, and impactful stories that resonate. Discover the Science Behind Great Stories - Why do some messages stick while others fade? Learn the psychology and neuroscience of storytelling in pharma. - Master the Framework - A step-by-step guide to crafting narratives that align with your brand's purpose and values, tailored for multiple stakeholders. - Leverage AI & Emerging Technologies: Explore how AI, wearable tech, and immersive experiences like AR and VR are revolutionizing pharmaceutical storytelling. - Learn from the Best - Real-world case studies from pharma and beyond, revealing how the most successful brands have harnessed storytelling to create impact. - Navigate Ethical & Compliance Challenges - Striking the balance between compelling narratives and regulatory constraints in a highly regulated industry. In today's digital era, where information is abundant but attention is scarce, stories have the power to transform how pharmaceutical brands connect, educate, and inspire. This book is an essential resource for pharmaceutical marketers, brand managers, sales teams, and medical affairs professionals who want to harness storytelling to drive engagement and business success. Your brand has a story-make sure it's the one people remember.
Metabolic Features and Nutritional Interventions in Chronic Diseases
A growing body of research indicates an extensive metabolic dysfunction in a spectrum of chronic diseases, comprising aging, cancer, and diseases affecting the cardiovascular system, liver, and kidneys. The phenotypes associated with metabolic dysfunction vary depending on disease type and stage. In turn, the altered metabolism drives disease pathology. Consequently, the nutritional modulation of metabolic status in chronic disease is widely acknowledged to reduce disease incidence. For instance, tailored nutritional intervention in cancers with altered metabolism determines the improved therapeutic responses. Additionally, counteracting muscle loss and osteoporosis are clinical goals of nutritional support in an aged population. Mechanistically, bioactive nutrients or tailored nutritional regimen modulate metabolism through mitochondrial homeostasis, immuno-regulation, as well as epigenome regulation to impact disease progression. This reprint aims to be an interdisciplinary platform that covers (1) characterization of metabolic features and/or nutritional requirement in a certain type of chronic disease; (2) defining the effects and mechanism of a specific nutrient or nutritional intervention on metabolism; (3) development of new nutritional strategy that improves disease outcome by altering metabolism.
Education and Communication in Veterinary Clinical Practice
Effective communication is a hallmark of successful veterinary clinical practice. Communication underpins professionalism, establishes effective teamwork, and is essential to veterinary-client relationships. Teaching or developing effective communication is an increasingly important component of the 'hidden' curriculum for veterinary educators, introduced and reinforced throughout the teaching program. Effective communication is also a focus for prospective employers when considering a new graduate. Successful communication must also consider the rapidly changing modalities of how people communicate and, importantly, how important communication will be toward resilience in a highly stressful profession. This Special Issue highlights what is effective communication, how this can be 'taught', and its importance toward veterinary clinical practice.
Dietary Habits and Metabolic Health
"Dietary Habits and Metabolic Health" examines the interplay between nutritional practices and metabolic outcomes, focusing on emerging research across diverse dietary factors. Key areas of exploration include the metabolic consequences of altered nutrient profiles in processed foods, such as protein and lipid oxidation products, glycosylation derivatives, and microbial-driven nutrient modifications. It also investigates the role of probiotics and prebiotics in modulating gut microbiota, metabolic pathways, and physiological responses under varying dietary patterns. Additional topics encompass the metabolic effects of dietary practices like energy restriction, single-nutrient limitation, and intermittent fasting, as well as connections between diet, gut microbiota composition, and chronic disease risk. The issue further highlights personalized dietary interventions as a tool for metabolic regulation. By synthesizing evidence from food science, nutrition, and medicine, this Special Issue aims to deepen insights into how dietary behaviors influence metabolic health and inform strategies for disease prevention and management.
Advanced Pharmaceutical Science and Technology in Israel
Israel has a significant and diverse history of ground-breaking research and development in pharmaceutical sciences and technology within academic settings, pharma/biopharma companies, and the biotech community. This Special Issue of Pharmaceutics, entitled "Advanced Pharmaceutical Science and Technology in Israel", was put together to highlight the exceptional achievements and significant international impact of pharmaceutical research performed in Israel in celebration of the country's 75th diamond anniversary of growth and prosperity. Naturally, the articles in this reprint represent only a small fraction of the ground-breaking pharmaceutical research and development taking place in Israel. That being said, this collection of articles does serve as a unique example of the outstanding and diverse contributions Israel has made to the global pharmaceutical arena. The Special Issue covers many hot topics in the pharmaceutical sciences, including gene therapy, cell-based therapy, nanomedicine, new drug delivery systems, 3D printing, space medicine, personalized medicine, and advanced PBPK modeling. We hope that this Special Issue will contribute to multidisciplinary discussions on these exciting topics and prompt new scientific collaborations, further advancing pharmaceutical sciences and engineering in Israel and globally. Looking to the future, Israel will undoubtedly continue to be a significant pioneer in the global pharmaceutical science and technology arenas.
Antimicrobial Activity of Natural Products and Plants Extracts
This reprint includes high-quality studies highlighting the complex antimicrobial potential of products derived from natural sources (NPs). The nine articles published in the Special Issue entitled "Antimicrobial Activity of Natural Products and Plants Extracts, 1st Edition" in the journal Antibiotics present scientific data regarding the ability of selected natural products (essential oils, gemmotherapy extracts, solvent extracts, isolated compounds) to inhibit relevant human and veterinary organisms (reference strains, multidrug resistant strains, ESKAPE Pathogens groups, etc.), as well as against bacterial and fungal strains specific to cereals. Interesting results on synergistic associations with antibiotics are reported as well. Furthermore, these studies offer insights into the NPs' chemical-profile-based standardization and multifaced biological properties-antioxidant, hepatoprotective, and cytotoxic-thus demonstrating the need for multidisciplinary studies.
Morphofunctional Nutritional Assessment in Clinical Practice
The diagnosis of malnutrition is difficult because it does not depend only on weight at a given time, but also on its evolution and the underlying pathological situations. Therefore, the clinical use of body composition measurements is essential for adequate assessment of this malnutrition, especially in the evaluation of muscle mass and function. In this context, nutritional assessment can no longer be based on the determination of classical anthropometric measurements. The concept of morphofunctional nutritional assessment postulates that the diagnosis and monitoring of nutritional status must be carried out using techniques and biomarkers that determine the evaluation of intake, anthropometry, body composition, muscle strength, and function that include techniques such as bioelectrical impedance analysis or nutritional ultrasound, and new biological parameters too. This Special Issue aims to show the implementation of this new concept of nutritional evaluation in the management of patients and in clinical research in nutrition.
Ecotoxicity and Herbal Health
Overviews environmental contaminants affect on plant-based remedies and, consequently, human health. Addresses several key areas of concern. It covers ecotoxicological impact on medicinal plants, human health implications, sustainable practices and remediation, regulatory framework and policy.
Pharmaceutical Stability & Stability Testing
Being foreword by Professor Abubakr O. Nur, University of Khartoum, this book combines the theoretical background of dosage form degradation and stability problems together with practical procedures to perform various types of stability studies. It describes the probable physical changes, the chemical kinetics of degradation reactions that may take place and the microbiological spoilage. It considers the influence of different factors on the stability of pharmaceuticals and their impact on the shelf life with emphasis on the effect of temperature taking in account the concept of the mean kinetic temperature and its calculation. The international regulatory guidelines together with the dosage form requirements and specifications and how to estimate or predict the shelf life with practical examples. This book is a valuable guide to students where they can found model question and answers, researchers and professionals of industrial pharmacy.
The Drug Book
"The Drug Book," edited by Charles Austin Bates, offers a fascinating glimpse into the world of pharmaceuticals and their social impact at the close of the 19th century. This historical work provides insights into the drugs, medicines, and remedies available during that era, reflecting the state of medical knowledge and practice.Explore the remedies and societal perceptions of various substances in an age before modern regulation and scientific advancements transformed the pharmaceutical landscape. This volume serves as a valuable resource for understanding the historical context of drug use and its evolving role in society.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
An Inquiry Into The Nature And Properties Of Opium
"An Inquiry Into The Nature And Properties Of Opium" delves into the historical understanding of opium, its properties, and its effects. Written by Samuel Crumpe, this work provides a detailed examination of opium's uses and impacts during its time. The book explores the chemical composition of opium, its medicinal applications, and the various methods of preparation and administration.Crumpe's inquiry offers valuable insights into the scientific and medical perspectives on opium prevalent in the 18th century. It serves as a historical record of the early investigations into one of the world's most potent and controversial substances.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The Monthly Magazine Of Pharmacy, Chemistry, Medicine
"The Monthly Magazine Of Pharmacy, Chemistry, Medicine" offers a fascinating glimpse into the state of medical and pharmaceutical knowledge during the 19th century. This historical periodical provides a detailed record of chemical discoveries, pharmaceutical practices, and medical advancements as they were understood at the time. Readers will find a wealth of information on the substances and techniques used in medicine, alongside discussions of contemporary scientific theories and debates. This magazine serves as an invaluable resource for historians of science and medicine, as well as anyone interested in the evolution of these fields.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
A Sociological Perspective on Blood Plasma Donation During the Pandemic
Shim and Baek examine the evolving existential meanings of gift-making by interviewing donors of convalescent blood plasma during the Covid-19 pandemic.The book reveals what plasma donation means for their efforts to reassemble their lives from being liminal moments to livable experiences, through interviews with convalescent donors in South Korea. It shows it is the very multiplex meanings of plasma donations that enabled people to effectively maneuver through the challenging liminality in life during COVID-19, by expanding the existing literature of gifts and donation that highlights the rich, complex meanings of the body parts donated. It presents a vivid dialogue between liminality and gift-making from varied narratives.A vital read for scholars, students of sociology, anthropology, and public health and those interested in how subjects reconstitute their agency amid uncertainty inside and outside the pandemic, so that we appreciate the voices of donors and learn from the lived experiences of those in this book.
A Treatise On Pharmacy for Students and Pharmacists
"A Treatise On Pharmacy for Students and Pharmacists" by Charles Caspari and Evander Francis Kelly, originally published in 1920, stands as a comprehensive guide to the principles and practices of pharmacy. Designed for both students embarking on their pharmaceutical education and practicing pharmacists seeking to enhance their knowledge, this treatise covers a wide array of topics essential to the field. From the fundamental concepts of pharmaceutical science to the intricacies of drug preparation and compounding, the book provides detailed explanations and practical insights. It delves into the chemical properties of medicinal compounds, exploring their interactions and effects within the human body. This historical text offers a valuable glimpse into the state of pharmaceutical knowledge at the turn of the century, making it an indispensable resource for anyone interested in the history of medicine and pharmacy.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
![Pharmacopoeia Officinalis [et] Extemporanea](https://cdn.kingstone.com.tw/english/images/product/0886/9781024320886m.webp?Q=cc709 "Pharmacopoeia Officinalis [et] Extemporanea")
Pharmacopoeia Officinalis [et] Extemporanea
"Pharmacopoeia Officinalis et Extemporanea: Or, A Complete English Dispensatory, In Two Parts. Theoretic And Practical" by John Quincy offers a comprehensive overview of pharmaceutical knowledge during its time. This historic text provides insights into the medications, preparations, and treatments that were commonly used. The book is divided into two parts, offering both the theoretical underpinnings and practical applications of pharmaceutical practices. It serves as a valuable resource for understanding the evolution of medicine and the role of the apothecary in past societies.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The British Homoeopathic Review
"The British Homoeopathic Review, Volume 39" offers a detailed look into the world of homeopathic medicine as it was practiced and understood in the late 19th century. This volume presents a collection of articles, case studies, and discussions relevant to homeopathic practitioners and those interested in alternative medical treatments. Providing insights into the historical context of homeopathy, the book showcases the theories, methodologies, and clinical applications that defined the field during this period. Readers will find valuable information about the remedies used, the diagnostic approaches employed, and the debates within the homeopathic community. This work serves as an important resource for understanding the evolution of homeopathy and its place within the broader landscape of medical history.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The Monthly Magazine Of Pharmacy, Chemistry, Medicine
"The Monthly Magazine Of Pharmacy, Chemistry, Medicine" offers a fascinating glimpse into the state of medical and pharmaceutical knowledge during the 19th century. This historical periodical provides a detailed record of chemical discoveries, pharmaceutical practices, and medical advancements as they were understood at the time. Readers will find a wealth of information on the substances and techniques used in medicine, alongside discussions of contemporary scientific theories and debates. This magazine serves as an invaluable resource for historians of science and medicine, as well as anyone interested in the evolution of these fields.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
An Inquiry Into The Nature And Properties Of Opium
"An Inquiry Into The Nature And Properties Of Opium" delves into the historical understanding of opium, its properties, and its effects. Written by Samuel Crumpe, this work provides a detailed examination of opium's uses and impacts during its time. The book explores the chemical composition of opium, its medicinal applications, and the various methods of preparation and administration.Crumpe's inquiry offers valuable insights into the scientific and medical perspectives on opium prevalent in the 18th century. It serves as a historical record of the early investigations into one of the world's most potent and controversial substances.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The Edinburgh New Dispensatory
"The Edinburgh New Dispensatory," published in 1804, stands as a comprehensive guide to pharmaceutical knowledge at the turn of the 19th century. This meticulously detailed volume includes complete and accurate translations of the London and Dublin Pharmacopoeias, offering invaluable insights into the era's medicinal practices. Authored by William Lewis and Andrew Duncan, this dispensatory reflects the evolving understanding of drugs, preparations, and their uses in medical treatment. A significant historical document, "The Edinburgh New Dispensatory" provides a window into the past for historians of medicine, pharmacy professionals, and anyone interested in the development of medical science. Its detailed entries and systematic organization make it an enduring resource for understanding the foundations of modern pharmacology.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Crude Drugs of Unani Medicine
Provides understanding and application of Unani medicine as cure, rehabilitation, and promotion of human well-being. Explores the theoretical and practical aspects of potential medicinal plants and their bioactive compounds to combat chronic ailments. Focuses on pharmacology and phytochemistry of medicinal plants and animal-derived drugs.
Practical Guide to Clinical Data Management
The management of clinical data, from its collection during a trial to its extraction for analysis, has become critical in preparing a regulatory submission and obtaining approval to market a treatment. Groundbreaking on its initial publication nearly 14 years ago, and evolving with the field in each iteration since then, this latest volume includes revisions to all chapters to reflect the recent updates to ICH E6, good clinical practices, electronic data capture, and interactive response technologies. Keeping the coverage practical, the author focuses on the most critical information that impacts clinical trial conduct, providing a full end-to-end overview for clinical data managers.Features: Provides an introduction and background information for the spectrum of clinical data management tasks. Outstanding text in the industry and has been used by the Society for Clinical Data Management in creating its certification exam. Explains the high-level flow of a clinical trial from creation of the protocol through study lock. Reflects electronic data capture and interactive response technologies. Discusses using the concept of three phases in the clinical data management of a study: study startup, study conduct, and study closeout, to write procedures and train staff.
Pharmacological Aspects of Essential Oils
Pharmacological Aspects of Essential Oils: Current and Future Trends provides a collection of therapeutic and pharmacological applications of the most researched essential oils of great importance derived from Clove, Cinnamon, Coriander, Turmeric, Thymus zygis, Thyme vulgaris, Ocimum basilicum, Copaifera spp, and Nigella sativa species. The new approach towards using a metal phenolic network with the essential oils as a tool of nanomedicine will surely open a new horizon for the research community. Treating disorders such as diabetes, insomnia, and obesity with essential oils will provide a new area of research. Aromatherapy, which is creating a market especially in the personal health care sector, is also discussed in the book. The relation between chemical composition and different biological properties is well discussed in respective chapters. The other practical topics related to the development of this industry of essential oils have been illustrated with elaborative figures and tables. Providing such updated data on the pharmacological applications of essential oils is an asset to the community associated with the extraction and production of essential oils, biochemist, aromatherapist, agrotechnologists, and nutritionist fraternities. Salient Features: Metal phenolic networks and essential oils as tool of nanomedicine Role of essential oils in aromatherapy Sophisticated development of various advanced techniques in the characterization of essential oils Pharmacological applications of Brazilian aromatic species Role of essential oils in management of diabetes, obesity, and insomnia
Effect of Nutrition on Maternal Health, Fetal Development and Perinatal Outcomes
It is evident that a multitude of lifestyle factors exert a considerable influence on the wellbeing of pregnant women and their foetuses. Of these factors, dietary behaviour is of particular significance. Despite the increased requirements for certain nutrients, such as iron and folic acid, during pregnancy, the fundamental principles of healthy eating remain consistent with those of the general population. A substantial body of research has established that an inadequate nutritional intake during pregnancy exerts a detrimental effect on perinatal outcomes, including complications during childbirth and suboptimal foetal development. Furthermore, this inadequate intake poses risks to the long-term health of the offspring. It is imperative to ensure an adequate intake of energy, protein, vitamins, and minerals in order to satisfy the needs of both the mother and the foetus.The developmental origin of health and disease (DOHaD) model hypothesises that the intrauterine environment can induce epigenetic modifications and alter gene expression patterns in the foetus. These alterations have the potential to render neonates and children susceptible to a range of diseases later in life. The formulation of national and international nutritional guidelines is meticulous, informed by robust evidence regarding the benefits of adequate nutrient consumption and the risks associated with deficiencies.
Surprised by Nothing
Kathryn Kyker used to faint at the sight of blood. But after three decades as an ER social worker, blood no longer fazed her-and neither did anything else.Kathryn took her job at a regional Georgia hospital because she was desperate for health insurance. Although she found the work meaningful and became the hospital's first ER social work manager, the high-stakes environment left her unable to cry, hypervigilant about safety, and detached from family and friends.With her inner emotional landscape sabotaged, Kathryn set out on a quest to regain her relationship with curiosity, joy, and the bonds that make us human. The result is a reflective interrogation of the US health care system, a meditation on social work, and a thoughtful inquiry into the emotional responsibilities we have to ourselves-and one another.Full of compassion and humorous insight, Surprised by Nothing is a compelling reminder of how to live a creative and nurturing life, even in the face of the world's random, devastating hardships.A portion of this book's proceeds will be donated to Project HOPE, which supports health care workers and improves access to care around the world.
Surprised by Nothing
Kathryn Kyker used to faint at the sight of blood. But after three decades as an ER social worker, blood no longer fazed her-and neither did anything else.Kathryn took her job at a regional Georgia hospital because she was desperate for health insurance. Although she found the work meaningful and became the hospital's first ER social work manager, the high-stakes environment left her unable to cry, hypervigilant about safety, and detached from family and friends.With her inner emotional landscape sabotaged, Kathryn set out on a quest to regain her relationship with curiosity, joy, and the bonds that make us human. The result is a reflective interrogation of the US health care system, a meditation on social work, and a thoughtful inquiry into the emotional responsibilities we have to ourselves-and one another.Full of compassion and humorous insight, Surprised by Nothing is a compelling reminder of how to live a creative and nurturing life, even in the face of the world's random, devastating hardships.A portion of this book's proceeds will be donated to Project HOPE, which supports health care workers and improves access to care around the world.
Biosimilars Development Strategies
After 18 years since the first biosimilar was approved, a lot has changed, from the regulatory guidelines to the stakeholder perceptions about the safety and efficacy of biosimilars. However, the development costs remain high, preventing faster entry into markets with more than 200 choices. Analyzing the regulatory filings of all approved biosimilars in the US and EU, a deep analysis of the scientific principles, and continuous challenges to the regulatory authorities have made it possible to plan the development on a fast track. This book teaches how to cut the current time and cost by more than 70%, based on the author's hands-on experience.Features: Describes the emergence of biosimilars since the first publication of the recombinant engineering patent, as well as a listing of all approved recombinant products, their patent expiry and their adoption across the globe. Provides a better understanding of the safety and efficacy of approved biosimilars. Global approval requires accommodating guidelines and detailed planning to avoid redundancy as well as high costs. The basic expectations of the agencies are presented here. Presents a detailed analysis of all EU and FDA-approved products with a comparative analysis. Renowned author and entrepreneur in the field of drug discovery and production.
Crude Drugs of Unani Medicine
Details pharmacology, phytochemistry, and pharmacovigilance of medicinal plants used in Unani system of medicine. Studies utilization of potential therapeutic agents as standardized extracts, in conjunction with other herbs or as isolated bioactive constituents.
The Unofficial Guide to Prescribing
Part of the unique and award-winning The Unofficial Guides series, a collaboration between senior students, junior doctors and specialty experts. This combination of contributors understands what is essential to excel on your course, in exams and in practice - as well as the importance of presenting information in a clear, fun and engaging way. Packed with hints and tips from those in the know, when you are in a hurry and need a study companion you can trust, reach for an Unofficial Guide. The Unofficial Guide to Prescribing provides detailed steps on patient assessment, investigation, and management, with an emphasis on prescription procedures. Through clinical scenarios, this work provides the necessary skills to excel in handling emergencies and complex prescribing. Prescribing errors have significant health implications for patients and financial implications for healthcare systems, costing millions annually. As such, early prescribing training has become a crucial necessity in medical education and is now an integral part of teaching and assessment. Each scenario is presented as you would see it in the hospital setting and covers: Initial step-by-step assessment of the patient: how to assess, assessment findings, and immediate managementInitial investigationsInitial managementReassessmentTreatmentHanding over the patientNew section on electronic prescribing and fluid prescribingDrug charts throughout to fill in with model answersCore theory around prescribing alongside practical applicationPrescribing taught alongside clinical managementAn enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
First Aid in Illness and Injury;
"First Aid in Illness and Injury" is a comprehensive guide to providing immediate medical assistance, written by James Evelyn Pilcher and originally published in 1899. This historical text offers invaluable insights into the medical practices and knowledge of the late 19th century, detailing essential techniques and procedures for handling various illnesses and injuries. Aimed at both medical professionals and laypersons, the book covers a wide range of topics, from basic wound care to more complex emergency interventions.Pilcher's clear and concise instructions make this book a valuable resource for anyone interested in the history of medicine or seeking practical advice on first aid. It provides a fascinating glimpse into the past, showcasing the challenges and innovations in medical care during a time when modern medical facilities were not always readily available. This edition preserves the original text, ensuring its historical and educational value for contemporary readers.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
