Developmental Dyscalculia
Developmental Dyscalculia: From Brain Mechanisms to Educational Applications presents research with a domain-general approach. It examines issues in the fields of numerical and non-numerical cognitive domains, neuro- mechanisms, and pedagogic issues to pave the way to a bridge between lab research, daily life, and curriculum applications, with a goal of finding a pathway to early diagnosis and interventions of developmental dyscalculia. It will be of interest to researchers with interests in cognitive neuroscience and education, to contribute fruitful discussions between education and neuro-cognition.
Introduction to the Neurophysiology of Movement
This introductory textbook explores how the brain and spinal cord regulate movement. It is designed for senior undergraduate and early-stage graduate or clinical students in movement sciences, physiology, neuroscience, biomedical engineering, physical therapy, occupational therapy, rehabilitation sciences and speech sciences.The book begins by presenting the fundamentals of cellular neurophysiology in a conceptual and accessible manner. It then explores key principles of sensory processing, using the somatosensory system as both a model system and a fundamental component of movement control.The motor system is discussed in detail, starting with the periphery (focusing on the motor unit) and progressing to motor areas in the cerebral cortex, cerebellum and basal ganglia. The roles of these regions are examined within the framework of three broad categories of movement: reflexes, rhythmic behaviours and voluntary movements. The book also discusses various neurological disorders affecting movement and outlines current therapeutic approaches.
Haematology (3rd Ed)
This core textbook provides a foundation in the molecular and cell biology that underpins haematology, allowing students to more easily understand the clinicopathological features of blood diseases, which are discussed in detail. The book covers all aspects of laboratory and clinical haematology, taking a practical approach by incorporating self-evaluation questions and learning objectives. These will give students not only the information needed to understand the topic but also clear indications of the core knowledge required to progress within the field of haematology.Building on the success of earlier editions authored by renowned haematologist Barbara J Bain, this textbook has been updated and expanded by seven experts in the field, with entirely new chapters on blood cancers and transfusion as well as new test cases and self-assessment questions. It is based on the curriculum of haematology teaching within Imperial College London, but it is equally suitable for medical students, trainee nurses, physician associate apprentices and biomedical science students from other institutions.
Innate Immunity: Pattern Recognition and Effector Mechanisms
This contributed volume follows up and expands upon Target Pattern Recognition in Innate Immunity (2009), providing a much-needed update on an area that has surged to the forefront of medical research in recent years. From the initial idea of pattern recognition on microbial surfaces, innate immunity is now recognized as a key player in human health and disease, by virtue of its ability to regulate adaptive immune responses with important physiological and pathological consequences. This book presents cutting edge research and future perspectives on nearly all aspects of innate immunity. Coverage includes cells of the innate immune system, pattern recognition receptors and effector mechanisms, soluble PRRs and humoral factors, immune response to viral, bacterial, fungal, and parasitic pathogens, disease mechanisms, and comparative studies in non-mammalian innate immunity. It is an excellent introduction to the field for students, and state of the art reference for researchers and professionals.
Haematology (3rd Ed)
This core textbook provides a foundation in the molecular and cell biology that underpins haematology, allowing students to more easily understand the clinicopathological features of blood diseases, which are discussed in detail. The book covers all aspects of laboratory and clinical haematology, taking a practical approach by incorporating self-evaluation questions and learning objectives. These will give students not only the information needed to understand the topic but also clear indications of the core knowledge required to progress within the field of haematology.Building on the success of earlier editions authored by renowned haematologist Barbara J Bain, this textbook has been updated and expanded by seven experts in the field, with entirely new chapters on blood cancers and transfusion as well as new test cases and self-assessment questions. It is based on the curriculum of haematology teaching within Imperial College London, but it is equally suitable for medical students, trainee nurses, physician associate apprentices and biomedical science students from other institutions.
Introduction to the Neurophysiology of Movement
This introductory textbook explores how the brain and spinal cord regulate movement. It is designed for senior undergraduate and early-stage graduate or clinical students in movement sciences, physiology, neuroscience, biomedical engineering, physical therapy, occupational therapy, rehabilitation sciences and speech sciences.The book begins by presenting the fundamentals of cellular neurophysiology in a conceptual and accessible manner. It then explores key principles of sensory processing, using the somatosensory system as both a model system and a fundamental component of movement control.The motor system is discussed in detail, starting with the periphery (focusing on the motor unit) and progressing to motor areas in the cerebral cortex, cerebellum and basal ganglia. The roles of these regions are examined within the framework of three broad categories of movement: reflexes, rhythmic behaviours and voluntary movements. The book also discusses various neurological disorders affecting movement and outlines current therapeutic approaches.
Wound Man
A spectacularly illustrated history of an enigmatic surgical diagram The Wound Man--a medical diagram depicting a figure fantastically pierced by weapons and ravaged by injuries and diseases--was reproduced widely across the medieval and early modern globe. In this panoramic book, Jack Hartnell charts the emergence and endurance of this striking image, used as a visual guide to the treatment of many ailments. Taking readers on a remarkable journey from medieval Europe to eighteenth-century Japan, Hartnell explains the historic popularity of this gruesome image and why the Wound Man continues to intrigue us today. Drawing on a wealth of original research, Hartnell traces the many lives of the Wound Man, from its origins in late medieval Bohemia to its vivid reincarnations in hundreds of manuscripts and printed books over more than three hundred years. Transporting readers beyond the specifics of bodily injury, Hartnell demonstrates how the Wound Man's body was at once an encyclopedic repository of surgical knowledge, a fantastic literary and religious muse, a catalyst for shifting media landscapes, and a cross-cultural artistic feat that reached diverse audiences around the world. The Wound Man, we discover, held profound importance not only for healers and patients but also for scribes, students, nuns, monks, printmakers, and poets. Marvelously illustrated, Wound Man sheds light on the entwined histories of art and medicine, showing how premodern medical diagrams represent a unique site of contact between sickness, cure, painting, and print.
Relations between epileptic seizures and headaches
In this groundbreaking clinical book, Dr. Gameleira presents a comprehensive analysis of the complex relationship between epileptic seizures and headaches, drawing from a detailed examination of 304 cases at the University Hospital of the Federal University of Alagoas. This thorough investigation delves into the intricate patterns of headache manifestation during various phases of epileptic episodes - from prodromal to postictal periods - offering valuable insights for both medical professionals and researchers. Through meticulous documentation and analysis, the study illuminates the chronological relationships between these neurological conditions, providing a deeper understanding of their interconnected nature. The research particularly examines the clinical characteristics of headaches during interictal, prodromal, ictal, and postictal periods, making it an invaluable resource for neurologists, epileptologists, and healthcare providers seeking to enhance their diagnostic and treatment approaches for patients experiencing both conditions.
Opioid free anathesia in laparoscopic surgery
This book will give you the chance to look differently at classical anathesitic techniques. Opioid free techniques are now used in many surgeries especially laparoscopic ones. In this book i give an approach of many to use instead of opioids making our patients ending their surgeries with less expected complications.I hope my work inspired you to use these techniques alot and experience new knowledge and skills.
An Overview Into the World of Cleft Lip and Cleft Palate
This is my library dissertation topic which I tried to put forward in the form of this book so that everyone can have a close and brief look in this world of cleft lip and cleft palate. As a fan of surgery and surgical procedures, I tried to include every aspect involved in regard to cleft lip and cleft palate. As we know that this is a vast topic so it's difficult to go in every detail, but I tried to include everything in brief.
A Comprehensive Look at Cancer Detection Devices
This book explores the latest advancements in cancer detection, highlighting innovative technologies, market trends, and key challenges in diagnostics. It examines the role of artificial intelligence, biomarkers, imaging techniques, and specialized laboratory tools in improving accuracy and efficiency. Additionally, it discusses market dynamics, patent landscapes, and the contributions of startups and major tech companies in driving innovation. By providing a comprehensive understanding of modern diagnostic methods, the book emphasizes the importance of research, collaboration, and investment in technology to enhance early detection, improve patient outcomes, and ultimately transform cancer care.
Shadow in Perpetuity
Cancer has in recent times acquired an eerie omnipresence in the minds of our countrymen as they see all kinds of personalities, big and small go down with the disease. Many of those affected, particularly those with financial muscle run abroad for treatment unreferred, by and large deluding themselves that that way they are outpacing the witty crab. Some jump from one practitioner to another, and from one centre to another in search of the solution. They are at the centre of the universe and must shake off the 'little dirt' sprinkled on them by the crab. One thing they are oblivious of is that cancer therapy is a long haul and cures are rare after four weeks of treatment abroad. The talks of 'we have cured you' are mere traps meant to entice more numbers. There are also those who resort to alternative therapies in the hope of avoiding conventional treatments for fear of their associated side effects, which is misinformed.
Psychodynamic Psychiatry
Psycho-dynamic psychiatry combines psychoanalytic principles with DSM-5 operational thinking. Major psychiatric disorders and personality dis-harmonies are presented psycho-dynamically, with an emphasis on intrapsychic functioning, on conflictuality, Freudian and neo-Freudian principles. The therapeutic framework as a landmark in the mind of the specialist is the reference to which psychiatric thinking appeals. The concepts of transference and counter-transference are essential, the relationship being healing through the power of containment of the specialist's mind, by referring to significant imago and to the stress-diary relationship. The psychoanalytic concepts of narcissism, symbiosis, twinning, false self, projection, projective identification, cleavage, dissociation are related to psychotic, neurotic, borderline, perverse functioning, in psycho-dynamic vision, but keeping the reference of international psychiatric diagnostic classifications. The book represents an interface between psychiatry and psychoanalysis, showing that the psychiatric patient is in a living dynamic, "an organism" whose history is written and rewritten according to the doctor-patient dynamic.
Team Dynamics and Cost-Effectiveness in Neurological Rehabilitation
This topic explores the crucial role of the multidisciplinary rehabilitation team-including physiatrists, physical therapists, occupational therapists, speech-language pathologists, nurses, and psychologists-in delivering comprehensive care for individuals with neurological conditions. It also examines the economic implications of neurorehabilitation, highlighting cost-effectiveness, resource allocation, and sustainability. Emphasis is placed on balancing high-quality patient outcomes with financial efficiency, making team-based care models indispensable for modern neurological rehabilitation practices.
Implant Failure and Complications
Dental implants are a valuable treatment option for better oral health and quality of life. However dental implants can fail at different points in time, starting from the time when they are inserted.Despite a higher rate of success, however there remains a significant no. of patients who develop peri implant mucositis and peri-implantitis. The definition of success for implants extends beyond merely implant survival.High survival rates and low complication rates of the prostheses are an important prerequisite for the general success of treatment, as failures of the prosthesis may result in failures of the entire implant rehabilitation. One of the most important strategies to reduce the risk of failure is a comprehensive pretreatment diagnostic work-up followed by the decision to fabricate either a fixed or a removable implant prosthesis.Therefore, while dental implants are increasingly becoming the choice of replacement for missing teeth, the complications associated with them are progressively emerging too.
Motor Learning and Recovery
Motor learning involves the acquisition and refinement of movement patterns through practice, leading to lasting improvements in functional abilities. Key theories like Dynamic Systems Theory emphasize the interaction between the individual, environment, and task to drive recovery.For neurological conditions (e.g., stroke), approaches such as: Constraint-Induced Movement Therapy (CIMT): Forces use of the affected limb to counteract "learned nonuse."Task-Oriented Training: Focuses on meaningful, real-world activities to enhance motor control.Robotics & Virtual Reality: Provide guided, repetitive practice to promote neuroplasticity.Bilateral Training: Uses simultaneous limb movements to stimulate neural recovery.Evidence supports these methods for improving motor function, particularly when tailored to individual goals and contexts. Emerging technologies and occupation-based strategies further optimize outcomes in rehabilitation.
Physiotherapy in Developmental Disorders
Developmental disorders are a group of conditions that affect physical, cognitive, language, and social development in children. These disorders typically emerge during early childhood and may include challenges in learning, communication, motor skills, and behavior. Common examples include autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), intellectual disability, and speech or language disorders. Early diagnosis and intervention are crucial for improving outcomes and helping children reach their full potential.
The Role of Resveratrol in the Prevention and Treatment of Cataracts
Non-surgical approaches to delay or prevent cataract formation have gained increasing interest in recent years. Among the numerous pharmacological candidates, resveratrol, a natural polyphenolic compound with potent antioxidant properties, has been extensively studied for its therapeutic potential. This book evaluates the available evidence supporting the use of resveratrol in preventing or delaying cataract development. Resveratrol holds significant promise as a non-surgical pharmacological agent for cataract prevention, particularly through its antioxidant and gene-regulatory functions. Combining pirenoxine (Catalin) with resveratrol and potentially with agents like taurine, N-acetyl cysteine or lipoic acid represents a rational, multi-targeted approach to delay cataractogenesis. Given the complementary mechanisms, particularly in oxidative stress modulation, protein protection, and cellular repair. This strategy could lead to more effective non-surgical management of cataract, especially in high-risk groups such as the elderly and diabetics.
Neural Repair and Rehabilitation
Neural Repair and Rehabilitation refers to the medical and therapeutic strategies aimed at restoring function following injury or disease affecting the nervous system. It includes a combination of physiological, psychological, and technological interventions to enhance recovery. Techniques such as neuroplasticity-based therapies, stem cell therapy, brain stimulation, and neurorehabilitation exercises help in restoring motor, cognitive, and sensory functions. A multidisciplinary approach-incorporating physiotherapy, occupational therapy, psychological support, and innovative tools like robotics or virtual reality-plays a crucial role in promoting independence and improving quality of life in individuals with neurological impairments.
Optimizing Neuro recovery
This document details neurorehabilitation strategies during the acute phase of neurological illness or injury (e.g., stroke, brain trauma). It highlights that early rehabilitation (or "early mobilization") aims to prevent deterioration, restore function, and reduce complications. Early rehab starts as soon as possible, including tasks like mobilization, positioning, physical therapy, and addressing complications (e.g., pain, infections, dysphagia).Key points include: Phases of rehabilitation: Different models (e.g., German Phasenmodell) guide the transition from acute care to rehabilitation.Common clinical issues: Disorders of consciousness, comorbidities (e.g., heart problems), pain, dysphagia.Complications: Immobility-related muscle loss, lung function decline, and critical illness myopathy/polyneuropathy.Interventions: Early mobilization, respiratory care, cardiovascular training, and specialized therapies for upper/lower extremities and aphasia.Psychological impact: Delirium, depression, and PTSD are common in ICU patients, requiring psychological support.
Use of Low Level Laser Therapy in Orthopedics
Discover the transformative potential of Low-Level Laser Therapy (LLLT) in modern medicine. This comprehensive guide bridges the gap between scientific understanding and clinical application, offering healthcare practitioners invaluable insights into this innovative treatment modality. From stroke rehabilitation to tendon healing, the book explores LLLT's wide-ranging applications, backed by clinical studies and cutting-edge research. Drawing from extensive clinical experience and evidence-based practices, this volume delves into the basic science of photobiomodulation while providing practical protocols for treating various conditions. Whether you're managing degenerative knee joints, addressing discogenic back pain, or exploring new frontiers in stroke rehabilitation, this authoritative resource offers clear guidance on implementing LLLT effectively. Written for medical professionals yet accessible to specialists and general practitioners alike, this book combines theoretical knowledge with practical applications, making it an essential reference for anyone interested in advancing their understanding of light-based therapeutic interventions.
The second case of Bardet-Biedl Syndrome associated with Keratoconus
Corneal ectasia is a group of progressive disorders characterized by thinning and protrusion of the cornea, which includes conditions such as keratoconus, keratoglobus, and pellucid marginal degeneration. Bardet-Biedl syndrome, a rare autosomal recessive genetic disorder, is primarily recognized for its hallmark features, including retinal degeneration leading to progressive vision loss, obesity, polydactyly, and various systemic abnormalities. While ocular manifestations are well-documented in Bardet-Biedl syndrome, the association with corneal ectasia, particularly keratoconus, is exceptionally rare. The first documented case of keratoconus in a patient with Bardet-Biedl syndrome was reported by Fran癟ois et al. in 1982. This book highlights the second known case of Bardet-Biedl syndrome associated with keratoconus, shedding new light on the potential systemic involvement of corneal ectasia in this syndrome. In addition, this book explores the latest evidence-based therapies for managing ocular abnormalities in Bardet-Biedl syndrome patients, including advancements in retinitis pigmentosa treatment.
Bacillus subtilis - Functionalities and One Health Applications
Tourism Case Studies in the Milieu of Georgia
The book offers a comprehensive collection of case studies, based on the Authors' three-decade experience of academic, professional, and personal domains. It features real-life, successful, and positive impact practices within the tourism sector in Georgia, encompassing human resource management, tourism education at both higher education and vocational levels, national and international tourism projects (CSR) and start-ups. Key cases include event management, marketing and branding of tourism products, SDG practices, popularization of intangible cultural heritage, resorts, and types of community-based, rural, and inclusive tourism, entrepreneurship, and risk management strategies. The book fosters the development of critical thinking, analytical, problem-solving, and decision-making skills, making it a valuable resource for students, scholars, and professionals engaged in tourism studies and practice.
Pharmacological reversal of cataract
Cataracts, a major cause of serious visual impairment, have been treated since ancient times, beginning with rudimentary methods like couching. Surgical techniques evolved significantly over centuries. Non-surgical approaches to delay or prevent cataract formation have been increasingly a focus of research. The study in this book aims to summarize and critically evaluate the existing evidence on the efficacy and mechanisms of pirenoxine in the management of cataract and related ocular conditions. Pirenoxine exhibits multiple pharmacological actions that may delay cataractogenesis. While promising, its global clinical use is limited due to the lack of large-scale randomized controlled trials. While Pirenoxine (Catalin) eye drops offer a pharmacological approach to delaying cataract progression via local ocular mechanisms, growing evidence suggests that systemic antioxidant supplementation may offer synergistic benefits.
Neuroanatomy for the Neuroscientist
It is truer in neurology than in any other system of medicine that a firm knowledge of basic science material, that is, the anatomy, physiology, and pathology of the nervous system, enables one to readily arrive at the diagnosis of where the disease process is located and to apply their knowledge at solving problems in clinical situations. The purpose of this textbook is to enable a neuroscientist to discuss the structure and functions of the brain at a level appropriate for students at many levels of study including undergraduate, graduate, dental, or medical school level. The authors have a long experience in teaching neuroscience courses at the first- or second-year level to medical and dental students and to residents in which clinical information and clinical problem-solving are integral to the course. The authors reach this object by integrating basic sciences with neurological clinical cases containing MRI, CT or fMRI images.
Smart Solar Grass Cutter for Lawn
The Solar Grass Cutter with Lawn Coverage is an eco-friendly, autonomous lawn maintenance system powered by solar energy. It uses a rechargeable battery, microcontroller (like Arduino), and ultrasonic sensors to navigate and cut grass efficiently while avoiding obstacles. Designed for sustainability and safety, it reduces energy costs, environmental impact, and the risk of injury. With adjustable cutting height and quiet operation, it offers a convenient and smart alternative to traditional lawn mowers, ideal for various lawn types and household use.
Cerebral Metastases: Translational Advances, Evaluation and Management
Cerebral Metastases: Translational Advances, Evaluation and Management, Volume 165 in this ongoing series, highlights new advances in the field, with this new volume covering many interesting topics, including Molecular Drivers in CNS metastasis, Role of the tumor microenvironment in CNS metastatic disease, Advanced Imaging to improve early diagnosis and evaluate treatment response, Liquid biopsy in early detection of CNS metastasis, Precision medicine approaches to CNS metastatic disease, IMRT/conventional RT, Single and hypofractionated SRS, Brachytherapy for recurrent metastases, LITT for treatment of active brain metastasis and radiation necrosis, and much more. Other topics covered include Minimally-invasive surgical approaches in the management of brain metastases.
Blockchain For Healthcare Data Management
This fascinating book delves into the transformative role that blockchain technology could play in the security and integrity of patient data within the healthcare sector.In an era where data breaches and privacy concerns loom large, blockchain has emerged as a potential solution to these challenges, offering a route to streamline healthcare processes, manage data and improve patient outcomes. The book begins by providing a comprehensive overview of its underlying principles, including decentralization, immutability and consensus mechanisms, before exploring, through a range of international cases studies, how blockchain has been applied so far within the healthcare sector, from the management of electronic health records (EHRs) and clinical trials to medical billing and supply chain management. The authors also explore the barriers to the wider adoption of blockchain, including financial investment and regulatory issues.The first book to focus solely on the potential of blockchain within the healthcare sector, it will appeal to international scholars, students and healthcare professionals interested in issues around patient confidentiality, data security and IT management.
The Ukmla Applied Knowledge Test
Are you a medical student preparing for the UKMLA exam? Look no further than The UKMLA Applied Knowledge Test: Clinical Presentations and Conditions. This comprehensive revision guide is an essential resource for any student looking to succeed in the exam. The text follows the General Medical Council's exam content map, covering all of the clinical presentations and conditions listed as being required for the examination. The text is further organised by 18 areas of clinical practice, each led by a specialist in the relevant field. The book features over 450 colour illustrations, and follows an easy to read, consistent layout throughout. Each topic covers clinical examination, diagnosis, management, treatment options and more. An essential preparation guide for UK based medical students, and students sitting the PLAB examination.
Negotiating In/Visibility
This volume brings together scholars from different disciplinary backgrounds to discuss how women contributed to the making, pedagogy, institutionalisation and communication of scientific knowledge in the twentieth century, and to reflect on the theoretical and methodological challenges of documenting such hidden contributions. Featuring examples from China, former Czechoslovakia, Greece, Hungary, India, Japan, Romania, the United Kingdom and the United States, the contributors discuss women's engagement with science across different institutional and non-institutional sites, ranging from the laboratory and the school to the clinic, the home and the media. The volume moves beyond the professional scientist model to enlarge our understanding of women's participation in twentieth-century science and document the complex combination of factors that rendered such contributions (in)visible to contemporaries and future generations.
