Nanoerythrocytes in Cancer Therapy
This book explores the theranostic potential of nanoerythrocytes against cancer. It provides a comprehensive overview, beginning with the evolution of erythrocytes into nanoerythrocytes and their crucial role as advanced drug delivery systems in oncology. It addresses the challenges in developing nanoerythrocytes, from safety and scalability to regulatory concerns. It provides a thorough examination of formulation strategies and technological advancements, covering the design, engineering, and optimization of nanoerythrocytes for precise drug delivery. Through case studies, recent patents, and clinical trials, this book reveals the latest advancements and future directions in the field. Furthermore, the chapters discuss the immune responses triggered by nanoerythrocytes and their implications for cancer treatment.Key Features: Explores the theranostic potential of nanoerythrocytes, integrating therapeutic and diagnostic capabilities of nanoerythrocytes for personalized cancer treatment Provides detailed insights into the design, drug loading, and release mechanisms that optimize nanoerythrocytes for targeted cancer therapies Investigates immune responses to nanoerythrocyte-based treatments, focusing on safety and efficacy in cancer therapy Addresses key development challenges--safety, scalability, and regulatory--of using nanoerythrocytes against cancer Discusses the latest innovations, patents, and trial outcomes of theranostic potential of nanoerythrocytes against cancer This book is a useful resource for researchers working in cancer biology, pharmaceutical sciences, and biomedical sciences.
Deaths From Restraints In Psychiatric Facilities
Post Traumatic Stress Disorder Treatment And Research
Complex General Surgical Oncology
Aimed for surgeons specializing in Complex General Surgical Oncology (CGSO), this work intends to help the reader prepare for board examinations and guide decision-making. Chapters focus on key content with an emphasis on evidence-based medical decision making. A supplemental section provides challenging scenarios. The book uniquely uses outlines and bullet points instead of prose. Chapters provide objective numbers that reflect a thorough understanding of each topic and are a valuable resource. We hope these will also aid the surgeon during patient conversations while early in their practice.
Receptor Tyrosine Kinases in Cancer
Receptor tyrosine kinases (RTKs) play a critical role in a variety of cellular processes including growth, differentiation, motility, and metabolism. RTKs are frequently overexpressed and their aberrant signalling is associated with various diseases including cancer. Thus, RTKs have become one of the most important druggable targets for the treatment of cancer. The emergence of small kinase inhibitors in cancer treatment offers a strategic approach to the management of cancer that surpasses the efficacy of traditional drugs. Understanding RTK signaling mechanisms is of paramount importance, especially as the US FDA and other global regulatory agencies have approved several small-molecule tyrosine inhibitors. Moreover, pharmaceutical companies are actively developing new compounds for the treatment of various malignancies. This comprehensive book addresses a timely need by presenting the latest advances and cutting-edge insights into RTKs in cancer research. The chapters provide overviews and recent developments regarding the roles of key RTKs --such as, c-Met, AXL, VEGFR, EGFR, among others--in pro-tumorigenic signaling, therapeutic resistance, and targeted inhibition across different cancer types. This volume serves as an essential resource for researchers and students seeking to deepen their understanding of this rapidly evolving field.