How to Be a Safe Consultant Vascular Surgeon from Day One
A highly pragmatic and down to earth guide to the "real-world" of vascular surgery, written to help trainees pass the FRCS (Vasc) examination first time around, hopefully with flying colours!
Magnesium
This book will help you learn more about magnesium and the important role it plays to our body. You will also learn all about the different forms available in the market as well as different foods you can eat to avoid deficiency! If you've ever wondered about the possibility of a mg deficiency, this book will help you take control of it and avoid the health risks that are related. You'll have all the information you need in no time! Some of the things the book will teach you are: What makes magnesium so importantThe symptoms of magnesium deficiency in your bodyHow you can increase the magnesium levels in your bodyHow medical professionals make use of magnesium in their emergency roomsThe general medical uses of magnesiumThe role that magnesium plays in the human bodyGives you a list of magnesium supplements with detailed explanations about themThis book is the perfect guide for understanding the nutritional benefits of foods and supplements that are high in magnesium, so you can choose which method best serves your individual needs. Between a poor diet and lack of nutritional foods that are readily available, it is easy to become malnourished and deprived of magnesium. But in these pages you will learn the signs and symptoms of magnesium deficiency and how to properly treat it.
Improving Quality of Life for Individuals with Cerebral Palsy Through Treatment of Gait Impairment
This book is based on presentations and discussions of a group of world-renowned experts during a symposium "International Cerebral Palsy Function & Mobility Symposium: Improving Quality of Life for Individuals with Cerebral Palsy through Treatment of Gait Impairment" which was held in Banff, Canada, in December 2019. Clinicians and scientists are paired to discuss the current state of knowledge, working at the border of what we know and what we don't, to advance the care of those with gait impairment due to cerebral palsy. Using authors with different focus, points of view, and ways of thinking, to help establish a framework to guide research efforts for the next five years and to ensure that progress continues to be made to improve the quality of life for those with gait impairments. Disparate topics are unified by a common format of bulleted key points and objectives at the beginning of each chapter and research goals at the end to make the results more rapidly accessible. Focus on gait and mobility in a clear, well-structured format. Enhances debate and exploration of issues. Challenges long-held assumptions to explore the current state of research, testing, and treatment and help direct it meaningfully. The disparate topics are unified by a common format of bulleted key points and objectives at the beginning of each chapter and research goals at the end to make the results more rapidly accessible. Presents objective, but also expert opinion, on how future research could be best directed. Patient goals need more attention, outcomes have stagnated, the details of the underlying neurological impairments are still a mystery, and strong evidence for what we do is desperately needed.
Slow Butterfly
Do you have an underactive thyroid? "I'm tired. I'm losing my hair. I can't lose weight. I have bad moods and feel like crap. They said the blood work is all fine. It's probably just stress." Hashimoto's thyroiditis is the most common cause of hypothyroidism-underactive thyroid-and the most common autoimmune disease in the world. Unfortunately, it's often not diagnosed properly, and when it is, monitoring or medication are the only options offered. As a result, many people suffer for months or even years without a diagnosis, and those on medication may still feel unwell, unable to live their best life. But this doesn't have to be the case. If you have an underactive thyroid, there is much you can do yourself to improve your symptoms and live more optimally. Your life should be more than just a matter of surviving day-to-day. Empower yourself so you can start to improve-today-wherever you are on your healing journey.
Slow Butterfly
Do you have an underactive thyroid? "I'm tired. I'm losing my hair. I can't lose weight. I have bad moods and feel like crap. They said the blood work is all fine. It's probably just stress." Hashimoto's thyroiditis is the most common cause of hypothyroidism-underactive thyroid-and the most common autoimmune disease in the world. Unfortunately, it's often not diagnosed properly, and when it is, monitoring or medication are the only options offered. As a result, many people suffer for months or even years without a diagnosis, and those on medication may still feel unwell, unable to live their best life. But this doesn't have to be the case. If you have an underactive thyroid, there is much you can do yourself to improve your symptoms and live more optimally. Your life should be more than just a matter of surviving day-to-day. Empower yourself so you can start to improve-today-wherever you are on your healing journey.
Deep Brain Stimulation Management
Deep brain stimulation (DBS) is now a firmly established treatment for movement disorders, and an increasing body of evidence supports DBS in the treatment of other neurological and psychiatric disorders. This essential reference guide outlines a practical approach to the use of this paradigm-shifting therapy and covers key aspects of DBS practice. Chapters describe how to implement a DBS program and select appropriate patients, device programming to achieve optimal symptom control, and long-term management of patients. Thoroughly revised, this third edition includes additional chapters on managing patients with emerging applications of DBS. An entire chapter is dedicated to troubleshooting common problems with the therapy as many 'failures' are preventable and addressable. With contributions from experts in the field, this is a must-have reference guide for any clinician working with DBS patients.
Treatment for Body-Focused Repetitive Behaviors
Treatment for Body-Focused Repetitive Behaviors is the first book to establish the theory and practice of a psychodynamic approach to treating body-focused repetitive behavior disorders (BFRBDs), such as hair pulling, skin picking, and cheek, lip, and cuticle biting.
Control of Breathing During Sleep
This book describes control of ventilation during sleep in both health and disease states. The topics are presented in a fashion that can be easily comprehended with many figures to illustrate complex concepts. Thus, a wide range of topics, starting from the site of normal respiratory rhythm generation to chemoreceptor control of sleep apnea, description of the apneic threshold, pathophysiology of upper airway closure, novel techniques to measure control of breathing, effect of cerebral blood flow on breathing, effect of opioids on ventilation, effect of heart failure on ventilation, genetic aspects of breathing disorders, age and gender differences, and various therapies are discussed. Key Features - Helps to bridge the gap between straight forward physiology and clinical practice through a range of topics and use of case vignettes- Explores various aspects of clinical management and control which is beneficial to sleep clinicians, respiratory physiologists, intensivists, trainees, and researchers.- Distills complex concepts into understandable language and figures, providing helping resource to the clinicians, that transforms a dry topic vis a viz control of ventilation into an exciting understandable 'clinician' language.
Stahl's Self-Assessment Examination in Psychiatry
As an excellent source of learning for prescribers specializing in psychiatry, primary care physicians, nurse practitioners, psychologists, and pharmacists, this new edition features approximately 150 questions, divided into ten core areas of psychiatry, helping to identify areas in which you need further study. The majority of questions are new or updated in their explanations and referencing. Each question is followed by an explanation of the answer and a list of references. After completing the questions you will be better able to: diagnose patients presenting with psychiatric symptoms using accepted diagnostic standards and practices; implement evidence-based psychiatric treatment strategies aligned with the patient's recovery goals; integrate recent advances in diagnostic and treatment strategies into clinical practice according to best practice guidelines. This collection has been approved by the American Board of Psychiatry and Neurology as part of a lifelong learning and self-assessment program and as a component of maintenance of certification.
Covid-19, an Issue of Cardiology Clinics
In this issue of Cardiology Clinics, guest editors Drs. Timothy D. Henry and Santiago Garcia bring their considerable expertise to the topic of COVID-19. Top experts in the field cover key topics such as prothrombotic effects of COVID-19; impact of the COVID-19 pandemic on acute myocardial infarction care; impact of the COVID-19 pandemic on cardiac arrest and emergency care; vaccine-related cardiovascular effects; and more. Contains 11 relevant, practice-oriented topics including cardiovascular manifestations of COVID-19; use and prognostic implications of cardiac biomarkers (Troponin); COVID-19: Insights from cardiac pathology; ACS in COVID-19; STEMI in COVID-19; and more. Provides in-depth clinical reviews on COVID-19, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Bookends
Toko●thanat●ology (n): The theoretical study of the parallels between birth and death, especially in medical care. What do birth and death have in common? They both represent times of profound change, when patients and their families need emotional support and empathy from their caregivers-things they don't teach in medical school. The practical skills and knowledge required to provide care in obstetrics and palliative care are essential. But dealing with the deeper meaning, the human connection, is equally important. The very nature of these events encourages the caregiver to walk alongside the patient, to assist rather than control.In Bookends, Dr. Susan Boron explores the powerfully human aspects of caring for people at both ends of their lives. She shows how expertise in one area of care easily transfers to the other, increasing confidence and improving care and satisfaction for practitioner and patient alike.
Bookends
Toko●thanat●ology (n): The theoretical study of the parallels between birth and death, especially in medical care. What do birth and death have in common? They both represent times of profound change, when patients and their families need emotional support and empathy from their caregivers-things they don't teach in medical school. The practical skills and knowledge required to provide care in obstetrics and palliative care are essential. But dealing with the deeper meaning, the human connection, is equally important. The very nature of these events encourages the caregiver to walk alongside the patient, to assist rather than control.In Bookends, Dr. Susan Boron explores the powerfully human aspects of caring for people at both ends of their lives. She shows how expertise in one area of care easily transfers to the other, increasing confidence and improving care and satisfaction for practitioner and patient alike.
The Future of Prevention and Treatment of Breast Cancer
The objective of this book is to provide a critical analysis of the present prevention strategies for breast cancer, emphasizing the cost benefits and quality of life of the patient. Rooted in the present knowledge of breast cancer biology and prevention and treatment options, the book will describe the future tools that could be available to oncologists and how these new approaches may change the landscape of recurrence and survival of the disease. Special emphasis will be given to the prevention strategies counterposing the present limitations and conflicting prevention guidelines for both hereditary and preventive non-hereditary breast cancer, and propose how the implementation of new strategies based on the present knowledge could save millions of lives and be more cost efficient. The book will present a critical status of the treatment and prevention of breast cancer and detail how a quantum leap could be achieved in the field by applying present basic research knowledge to clinical application.
Applied Peritoneal Dialysis
This book offers a comprehensive guide to peritoneal dialysis (PD). Home dialysis, and more specifically PD, is growing in popularity in the US. By conservative estimates, experts suggest that 45 percent of dialysis patients in the US can be on home dialysis. However, the current penetration rate is only 10 percent. This is changing with an expected major increase in the next 5 years. One of the reasons for the low uptake is that many nephrologists lack comfort and confidence in using PD as a dialysis modality. This book addresses those concerns by covering all aspects of PD. Chapters include its history, patient selection, implementation options, comorbidities, quality of life concerns, and developing approaches to treatment. This comprehensive resource fills the unmet need for a practical, hands-on book that is both detailed and can work as a quick reference. This is an ideal guide for academic nephrologists, private practice nephrologists, NPs, PAs, nurses, fellows, and residents.
Chordoma of the Spine
This book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma. Written by world experts from leading chordoma centers, Chordoma of the Spine serves as a valuable reference for spinal oncologists and general spine surgeons who may encounter chordoma patients in their practice. It provides the most up-to-date evidence regarding all aspects of treating patients with this disease. By focusing on this specific pathology of the spine, this resource condenses expert-level research into understandable treatment algorithms.
Ovarian Stimulation
Ovarian stimulation is the starting point of reproductive medicine but the procedure can result in adverse reactions particularly the dangerous ovarian hyperstimulation syndrome. Fully revised in line with modern practice of ovarian stimulation, this new edition is divided into six sections that cover mild forms, non-conventional forms, IVF, complications and their management, alternatives, and the practicalities of procedures. All aspects of ovarian stimulation are discussed including the different stimulation protocols from which to choose, the management of poor responders and hyper-responders, as well as stimulation in patients with PCOS. Comprehensively reviewing the modern approach to ovarian stimulation, the alternative procedures are also described, both in IVF and other methods of assisted reproduction. Written by leading experts on reproductive health and fertility, this book will assist infertility specialists, gynecologists, reproductive endocrinologists and radiologists in determining successful treatment for their patients.
The Acute Neurology Survival Guide
This practical guide for trainees and advanced practice providers covers the essential management of hospitalized patients with acute neurologic conditions. Divided into five sections, this text serves as an incredibly easy-to-use, visually accessible, how-to manual that covers exactly what every responding clinician needs to know to care for the patient in front of them.The first section provides tangible guidance about how to pre-round, structure a presentation, examine neurologically ill patients, and interpret the core diagnostics obtained in many neurology patients: CT, MRI and EEG. The next three sections cover common complaints encountered in the hospital: spanning from non-vascular admissions, vascular & stroke neurology topics, and core neurocritical care principals and chief complaints. Throughout are checklists, scoring systems, pro-tips, images, helpful reminders, as well as concise summary of the pertinent literature. This is an ideal guide for medicalstudents, neurology & neurosurgery trainees and advanced practice providers, as well as experienced professionals who want to brush up on the latest updates.
The Psychodynamics of Medical Practice
The Psychodynamics of Medical Practice: Unconscious Factors in Patient Care delves into the profound yet often overlooked influence of unconscious psychological processes in medical practice. This thought-provoking volume examines how physicians' personal emotions, unconscious defenses, and countertransference impact patient care, decision-making, and professional relationships. Drawing from psychoanalytic concepts, the book highlights the interplay between the doctor's own psychological framework and the clinical environment, shedding light on the hidden dimensions of medical interactions. By exploring concepts such as projection, externalization, and projective identification, the book provides a nuanced understanding of how physicians unconsciously manage anxiety, navigate difficult patient encounters, and interpret clinical realities. Through real-life case studies and interdisciplinary insights, it underscores the necessity of self-awareness in medical education and practice. Advocating for a more reflective approach to medicine, the book argues that recognizing and addressing unconscious biases can enhance diagnostic accuracy, improve doctor-patient relationships, and ultimately lead to more compassionate and effective healthcare. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1985.
The Psychodynamics of Medical Practice
The Psychodynamics of Medical Practice: Unconscious Factors in Patient Care delves into the profound yet often overlooked influence of unconscious psychological processes in medical practice. This thought-provoking volume examines how physicians' personal emotions, unconscious defenses, and countertransference impact patient care, decision-making, and professional relationships. Drawing from psychoanalytic concepts, the book highlights the interplay between the doctor's own psychological framework and the clinical environment, shedding light on the hidden dimensions of medical interactions. By exploring concepts such as projection, externalization, and projective identification, the book provides a nuanced understanding of how physicians unconsciously manage anxiety, navigate difficult patient encounters, and interpret clinical realities. Through real-life case studies and interdisciplinary insights, it underscores the necessity of self-awareness in medical education and practice. Advocating for a more reflective approach to medicine, the book argues that recognizing and addressing unconscious biases can enhance diagnostic accuracy, improve doctor-patient relationships, and ultimately lead to more compassionate and effective healthcare. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1985.
Mother To Be
As wonderful and magical as it is, becoming a mother for the first has its own set of challenges. Before this point in your life, you've known about motherhood from friends and family members but that's nothing like experiencing your first-ever pregnancy because every pregnancy is unique in its own way.Becoming a first-time mother can be quite scary and rightfully so because you'll be navigating a major life transition without getting much sleep and having any benefit of experience. However, it's important to remember that, with time, you'll adjust to your new routine and your confidence in your parenting skills will grow as well. And who knows, pretty soon you may consider expanding your little family again.When you first find out that you're pregnant, it's completely normal to feel a mix of emotions and not know what to do because there's a lot of information out there and you can't know what's right for you and your baby until you get yourself checked. It's important for you to consult with a licensed doctor and follow their advice every step of the way.It's no secret that first-time motherhood is especially hard because no matter what you do and how prepared you are, you can never be fully ready for what may happen and you can always expect plenty of surprises along the way. This will be the first time in your life where you have no choice but to transition from self-centered living to selfless living all for the sake of the baby that's growing inside.If you're feeling lost about how to prepare for the next nine months, this book covers everything you need to know about overcoming your fears and insecurities about pregnancy, preparing for what you can expect in all three trimesters, your baby's journey from conception to birth, and how you can be the best mother your baby can ask for.
Advances in Cardiovascular Technology
Advances in Cardiovascular Technology: New Devices and Concepts is a comprehensive reference for cardiovascular devices of all types. For engineers, this book provides a basic understanding of underlying pathologies and their prevalence/incidence. It also covers what devices are available, how they are clinically used, and their impact on pathophysiology. In addition, the book presents the constraints imposed on device design and manufacture by the environment in which it is used (e.g., exposure to tissues within the body, blood in particular) and the primary requirements for each specific type of device, including its durability and resistance to fatigue. For clinicians, this book contains information on primary engineering challenges, the types of devices available, their advantages and disadvantages, and the (current and emerging) tools and materials available to device designers.
Paediatric Haematology and Oncology
Fully revised and updated for its second edition, Paediatric Haematology and Oncology provides an easily accessible source of information about all of the basic principles of childhood cancer and leukaemia, and detailed specialist knowledge on how to care for children with those conditions. Featuring new chapters on the biology of childhood leukaemia and central nervous system tumours, the book includes a greater focus on the rapidly expanding research in the biology and genetics of childhood malignancy, as well as new clinical treatments and more detail on various tumour types. Logically split into 12 sections on different aspects of haematology and cancer to allow quick and easy reference, the book provides general principles of diagnosis and treatment, short- and long-term care, and oncological emergencies, before moving on to chapters on specific diseases. Normal values and useful websites are also included for reference. Chapters have been expanded to feature more clinical images to aid in diagnosis and interpretation, making this second edition an invaluable companion for the trainee and consultant in paediatric haematology and oncology.
Best of Five McQs for the Endocrinology and Diabetes Sce
Best of Five MCQs for the Endocrinology and Diabetes SCE is a dedicated revision guide designed to assist candidates in preparing for the Endocrinology and Diabetes Specialty Certificate Examination (SCE). It contains 350 best of five questions covering the main themes of the specialty curriculum. The questions mirror the format that the candidates can expect to find in the exam and cover all of the key topics, including pituitary gland and hypothalamus, thyroid gland, parathyroid gland and bone disease, adrenal glands, reproductive endocrinology, and diabetes and lipid metabolism. Explanatory answers include references to the most up to date NICE and international guidelines as well as other literature to enable further reading and study. This second edition has been fully updated, with 20 extra questions added to the diabetes chapter to reflect the new exam weightings. Providing a thorough assessment of the reader's endocrinological knowledge, this is the only revision book candidates will need to pass the Endocrinology and Diabetes Speciality Certification Examination first time.
Pediatric Thoracic Surgery
This book discusses all thoracic diseases of surgical interest, from thorax malformations to airways disorders.It is divided into six main sections; the first two analyze general aspects, while the following three focus on malformations of the thorax, airways, esophagus and diaphragm. The final section describes the main pediatric tumors involving the chest and internal thoracic organs. Each chapter starts with a classification of the main pathologies related to the anatomical region considered. For each pathology, the various aspects of the diagnostic-therapeutic procedure are described in details - from the clinical presentation and diagnosis to the pre-operative preparation, the surgical aspects, and the post-operative course. Possible future developments are also evaluated.The volume will be a useful tool for specialists in pediatric and thoracic surgery, but will also represent an educational resource for medical and nursing students.
Dsm-5-Tr(tm) Clinical Cases
This book clarifies and discusses psychiatric diagnosis with a particular focus on how diagnoses have evolved from DSM-5. The cases are followed by a discussion by an expert clinician, who describes an approach to diagnosis through an exploration of psychiatric and personal history, symptom clusters, laboratory tests, and clinical ambiguities.
A Complex Systems Approach to Epilepsy
The epilepsies are devastating neurological disorders for which progress developing effective new therapies has slowed over recent decades, primarily due to the complexity of the brain at all scales. This reality has shifted the focus of experimental and clinical practice toward complex systems approaches to overcoming current barriers. Organized by scale from genes to whole brain, the chapters of this book survey the theoretical underpinnings and use of network and dynamical systems approaches to interpreting and modeling experimental and clinical data in epilepsy. The emphasis throughout is on the value of the non-trivial, and often counterintuitive, properties of complex systems, and how to leverage these properties to elaborate mechanisms of epilepsy and develop new therapies. In this essential book, readers will learn key concepts of complex systems theory applied across multiple scales and how each of these scales connects to epilepsy.
Nurse Florence(R), How Do We Hear Things?
Sometimes it seems only a nurse can bring technical information down to an understanding that an ordinary person can grasp. The Nurse Florence(R) book series provides high quality medical information that even a child can grasp. By introducing young kids to correct terminology and science concepts at an early age, we can help increase our children's health literacy level as well as help to prepare them for courses and jobs in Science, Technology, Engineering, and Math. We need more scientists so I hope that many children will enjoy this book series and consider a job involving science.
Microbes and Oral Squamous Cell Carcinoma
This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention.The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like forthis area of research.The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
![Child and Adolescent Clinical Psychopharmacology Made Simple [16pt Large Print Edition]](https://cdn.kingstone.com.tw/english/images/product/7103/9780369387103.webp "Child and Adolescent Clinical Psychopharmacology Made Simple [16pt Large Print Edition]")
Child and Adolescent Clinical Psychopharmacology Made Simple [16pt Large Print Edition]
A classic in its field, Child and Adolescent Clinical Psychopharmacology Made Simple provides parents, therapists, and health care professionals all they need to know about the use of psychoactive medications in the treatment of childhood and adolescent psychological disorders in easy-to-understand language. This fully revised and updated fourth edition includes new information about sleep disorders, sleep medication, substance abuse, and more.
Dermal Drug Delivery
Over the last 10 years there have been many changes in the development, control, and regulation of transdermal and topical products. Various quality issues have been reported by patients and practitioners resulting in the recall or removal of products from the market. With chapters written by experts in this field, this book takes a 21st century
Latest Advances in Diagnosis and Treatment of Women-Associated Cancers
There has been tremendous progress in cancer diagnosis and treatment methodologies, and this book focusses on major cancers of cervix, breast, endometrium, and the associated reproductive system affecting women, using computational tools, Nano medicine, Machine Learning (ML), Artificial Intelligence (AI), Big Data and other latest techniques.
In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development
This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.In Vitro Bioassay Techniques for Anticancer Drug Discovery and Deve
Oncologic Thermoradiotherapy
The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.
Precision Medicine in Cardiovascular Disease Prevention
Social Determinants.- Biomarkers.- Genetics.- Atherosclerosis Imaging.- Digital Health.- Artificial Intelligence and Machine Learning.- Novel Research Designs.- Shared Decision Making.
Controversies in Testosterone Deficiency
This book aims to address a number of controversies concerning the use of testosterone treatment. It explains topics that clinicians regularly encounter such as whether to use free or total testosterone in the evaluation of the patient with testosterone deficiency; what factors actually impact testosterone levels, polycythemia, gynecomastia, bone density, and hyperprolactinemia in the testosterone deficient patient; critical analysis of the numerous questionnaires that are available to clinicians; and the impact of testosterone therapy on male fertility, cardiovascular disease, and prostate events including prostate cancer. Guiding the reader in both evaluation and management, the book also illuminates novel concepts in the T space such as testosterone use in the transgender population, T therapy as an endothelial modulator, bipolar testosterone therapy in the patient with advanced prostate cancer, and testosterone therapy as a performance enhancer.Controversies in Testosterone Deficiency is intended for any clinician involved in the care of patients with testosterone deficiency, exploring hot topics and correcting existent misinformation in the routine care of patients.
Neuro-Behavioral Manifestations of Prader-Willi Syndrome
The behavioral issues experienced by individuals with Prader-Willi Syndrome (PWS) can be both surprising and overwhelming to clinicians and caregivers. Despite the distress and dysfunction posed by them, there are very few resources available to address these neuropsychiatric problems. This invaluable guidebook helps to identify and address the spectrum of behavioral issues faced by individuals with PWS. Written by a psychiatrist with unique expertise in the management of patients with this condition, this easy-to-read book explores practical details that will aid any clinician or caregiver. Chapters offer vivid case examples and clear guidance on both the behavioral and pharmacological management of issues such as anxiety, skin-picking, ADHD, disruptive behavior (including non-suicidal self-harm), mood disorders (including depression and bipolar disorder), and psychosis. Neuro-behavioral Manifestations of Prader-Willi Syndrome serves as an essential and practical companion for any caregiver or healthcare professional providing care to people with PWS.
What Makes a Person?
Ever wondered why your life and health can sometimes be so hard to control? Or why it seems so easy for other people? Mark Hanson and Lucy Green draw on their years of experience as scientists and educators to cut through the usual information on genetics and lifestyle to reveal the secrets of early development which start to make each of us unique, during our first 1,000 days from the moment of conception. Some surprising discoveries, based on little-known new research, show how events during our first 1,000 days make each of us who we are and explain how we control our bodies, processes that go way beyond just the genes which we inherited. Provoking new ways of thinking about being parents, this book empowers individuals and society to give the next generation the gift of a good start to life and future health.
Unaging
Aging is a subject of concern to everyone, but is widely misunderstood. If we view it as inevitable, we miss the fact that not everyone is able to grow to an old age. Realization of this reality helps us to understand that aging presents a wonderful opportunity - an opportunity to make choices about how we live which can enhance the aging process and offer a chance to live to our potential. This book clearly presents the four, multiple reserve, factors (cognitive, physical, psychological and social) which impact our ability to have healthy responses to the stresses of aging. By giving the biological basis for the advice given, you will learn the steps to take in your activities, diet and mental outlook to grasp the opportunity that aging offers. Everyone must know that what we do makes a difference.
Personalized Drug Screening for Functional Tumor Profiling
Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology.
Long Non-Coding Rnas in Cancer
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.
Diabetes Drug Notes
DIABETES DRUG NOTES Diabetes is becoming more common in both older and younger generations and in keeping with this escalation in cases, there are an ever increasing number of drugs and drug classes that are suitable to treat hyperglycaemia. In a unique blend of diabetes practice, clinical pharmacology, and cardiovascular medicine, Diabetes Drug Notes describes the principles of clinical pharmacology with regards to diabetes prescribing. Each drug class for the treatment of diabetes is covered in detail, along with the effect on the cardiovascular and renal systems caused by each drug. Building upon the success of their "Drug Notes" series for Practical Diabetes and their "Drugs for Diabetes" series in the British Journal of Cardiology, the team of experts focuses on the glycaemic management of type 1 and type 2 diabetes, with other effects of antidiabetic drugs covered as well. Diabetes Drug Notes also includes: Comprehensive and up-to-date coverage of the drugs for the glycaemic management of patients with type 1 or type 2 diabetes Expert reflection on prescribing considerations for special groups, as well as common pitfalls in prescribing Detailed case histories to illustrate relevant information Summaries of recent guidelines related to diabetic intervention Diabetes Drug Notes is a user-friendly guide for a general diabetes medical, nursing, and pharmacology readership, as well as those who support them.
Tremors
Tremor is the most common movement disorder. The breadth of work remaining in tremor pathophysiology, etiology and treatment development does not render the area intractable; on the contrary, this is a dynamic, rich research area sure to continue its rapid growth. In Tremors, experts in the field come together to discuss the underpinnings of neurological tremors and recent clinical findings in treatment models. This volume is broken into the following sections: - "Tremor Foundations" presents work across research modalities, providing an overview on the underpinnings of tremor as symptom and disease. Recent developments in the understanding of tremor pathology, pathophysiology, and genetics, aided by groundbreaking discoveries using neuroimaging techniques, allow glimpses into future breakthroughs to come. -"The Family of Tremors" presents the full extended range of tremor presentations, spanning isolated tremors, tremor as one of several features of a neurological disorder, and other hyperkinetic movement phenotypes commonly referred to, mimicking or framed as tremors. -"Tremor in the Clinic" reviews the growing knowledge range of clinical topics in tremors. Advances in assessing tremor bring pathophysiology concepts into clinical use, opening an active era in new therapeutic development. Clinical researchin tremors also now encompasses more holistic treatment approaches, novel treatment modalities, and diversity and inclusivity, all areas likely to feed back into basic etiology and pathophysiology research of this common movement disorder. Tremors will prove to be a useful text for practicing clinicians, students and researchers focusing on movement disorders, and those living with tremor who want to learn more about their condition.
Developmental Origins of Health and Disease
The concept of the early life developmental origins of health and disease (DOHaD) in adults has stimulated a new approach to understanding disease trajectories, with major public health implications. Indeed, the principle of the 'lifecourse of disease' now influences health policies internationally. Environmental influences during pregnancy and early life that affect lifelong health are well documented, but there is a new focus on the preconception period and the significance of paternal health on the fetus. This fully revised second edition highlights scientific and clinical advances in the field, exploring new understanding of mechanisms such as epigenetics and the increasingly recognised role of external influences, including pollution. The book is structured logically, covering environment, clinical outcomes, mechanisms of DOHaD, interventions throughout the lifespan and finally implications for public health and policy. Clinicians and scientists alike will improve their understanding of the developmental origins of health and disease with this essential text.
To Hear Again, to Sing Again: A Memoir by Ellis Douek, Ent Surgeon and Hearing Implant Pioneer
This is an autobiography of Ellis Douek, one of the pioneers of hearing implants, whose name lives on through the middle ear device Douek-MED(TM). Shedding light on the life of a surgeon from the early days of the UK National Health Service, it not only covers the highlights of Douek's medical career but also contains sensational, no-holds-barred tales of his interactions from ordinary patients to well-known singers, kings, emperors and dictators. We read about a social dinner-turned-mass consultation session for the entire Cabinet; using an innovative hearing test to expose a financial scam; a wife who dumped her loyal husband after being cured; a curious encounter with Michael Jackson; and not getting paid by Gaddafi's staff, causing an epic coup by the Libyan dictator on his own embassy. It is at once unflinching and compassionate, offering a searingly honest firsthand account of his trailblazing journey to leave a mark in history.Blending pioneering research and a unique episodic storytelling approach, To Hear Again, To Sing Again is a profound reflection on the relationship between doctor and patient, and one man's quest to make a difference in the world.
100 Years of Insulin
The book celebrates the centenary of the discovery of insulin and traces the developments in the types of insulin preparations used by patients with diabetes today. It is written for the lay public and presents the drama of the discovery including humorous and personal accounts of the many colourful characters in the insulin story.
Functional Medicine for Antidepressant Withdrawal
Since the days of the "Psychopharm Revolution," antidepressant medications such as SSRIs and SNRIs have been a foundation of modern psychiatric practice. Today, 40 million Americans take antidepressants, and global antidepressant prescribing is on the rise. Simultaneously, however, a gap has emerged between pharmacologic innovation and methodology. Amidst patient reports of antidepressant side effects, evidence is mounting that antidepressant discontinuation often leads to withdrawal - which can be severe. And although today's clinicians are trained how to prescribe antidepressants, they are not trained how to safely stop them. There is currently zero field-wide consensus regarding antidepressant discontinuation best practices. In addition to a stunning ethical failure, this represents a serious void in the psychiatric model... a riddle that too many patients and clinicians are being forced to solve alone. Functional Medicine for Antidepressant Withdrawal presents a comprehensive, evidence-based paradigm for antidepressant discontinuation that prioritizes the repletion of underlying nutritional deficiencies. Bridging concept and application, it provides health professionals with clinically proven tools for mitigating antidepressant withdrawal and guiding patients successfully through taper. It also reveals a path to the standard of care that we all deserve, one illuminated by science and upheld by the mandates of ethical, conscientious, personalized medicine.
