Looking Within
"Compelling and insightful-I urge everyone, physicians and the public alike, to read this brilliant work." -James Borgstede MD, past president and chairman of the board of the American College of RadiologyA doctor's profound tales of diagnoses and discoveries made by medical imaging; and reflections on what we can learn about ourselves and life by looking within the human body.What would it really be like to have x-ray vision? Our bodies have endless stories and secrets to tell, and imaging is the great equalizer. When we look deep into ourselves from the vantage of this fundamental level, with exterior barriers and labels removed, we may see ourselves, other people, and our lives in a whole new light.In Looking Within, Cullen Ruff, MD collects over 30 stories of how diagnostic imaging impacted the lives of his patients and provided insight into the many complex stories that led these people to seek answers. Ruff highlights the wonder and mystery of the human body, literally and metaphorically looking inside of others. Each story describes a patient in whom a life-changing discovery is made: tumors, stroke, domestic violence, substance abuse, sterility, unexpected pregnancy, infection, surgical complications, evidence of criminal activity, mental illness, even impending death. Dr. Ruff's words, images, and insights help us see ourselves like never before.
Artificial Intelligence in Medical Diagnostics
Common Sense Labs
Updated and Expanded Edition of the Bestselling Book Common Sense Labs! Features the latest medical research and insights, offering a more comprehensive explanation of blood tests. Blood tests are one of the most effective and accessible tools for monitoring your health, but in today's fast-paced healthcare system, patients often leave the doctor's office with little understanding of which tests to request, why they're important, or how to interpret the results. Doctors, often pressed for time, may not fully explain the details, leaving many feeling confused and unsure. In response to this widespread issue, Dr. Ken Berry, a trusted family physician, and Kim Howerton, a certified health coach, have teamed up again to create the updated and expanded edition of their bestselling book Common Sense Labs. Maintaining the clear and accessible format of the original, this edition goes even further to help readers demystify blood work, understand what tests to get, interpret results, and take steps toward better health. In this comprehensive guide, you will discover: Which important lab tests go beyond standard physicians' orders to help you better assess your healthHow to interpret your results beyond the average rangesHow to take control of your health and make informed decisions with confidenceHow blood work can diagnose and help you manage common health conditionsPractical strategies for improving your health based on your lab results Expanded and Updated Features: New and Updated Content: This second edition incorporates the latest medical research and insights, offering readers a more comprehensive understanding of a broader range of key blood tests.Clear, Accessible Explanations: Dr. Berry and Howerton break down complex medical concepts into simple, understandable language, empowering you to confidently interpret your own blood work.Trending Health Topics: New sections cover emerging health concerns like inflammation markers, metabolic health, hormone balance, and advanced cholesterol testing, reflecting current trends in preventive care.Tools and Advice: Charts, checklists, and graphs to help readers understand optimal levels for health markers and actively participate in their health journey and track their lab results. With expert insights and practical advice, Common Sense Labs empowers you to take control of your health by understanding your blood work and making meaningful changes for a healthier future. Whether you are aiming to optimize your health, better understand your current lab results, or take proactive steps toward wellness, Common Sense Labs is the essential guide to navigating your blood work with clarity and confidence.
Hematopathology
Part of the popular Foundations in Diagnostic Pathology Series, Hematopathology, Fourth Edition, is a practical and affordable resource that is ideal for study and review as well as everyday clinical practice. With its highly templated format, clearly written text, and concise summary tables, this user-friendly reference helps both trainees and practicing pathologists form accurate diagnoses, avoid pitfalls, and confidently sign out pathology reports on these often difficult and challenging cases.Uses a highly templated format that includes clinical, imaging, and management/prognostic features; pathologic features; ancillary studies; differential diagnosis; and selected bibliographyFocuses on the specific features of various entities, including differential diagnosesSupplements traditional morphologic diagnostic pathology with clinical, immunohistochemical, and molecular genetic information throughoutIncludes new information on the molecular biology of benign and malignant hematologic disordersContains numerous quick-reference summary boxes that provide concise and handy key points on the clinical features and pathological features of each disease within hematopathologyFeatures hundreds of full-color photomicrographs and gross photographs that depict important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual casesReflects updated disease classifications according to the 5th edition of World Health Organization (WHO) and The International Consensus Classification (ICC)Offers contributions from internationally recognized pathologists, keeping you up to date with the latest information in the fieldAn eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology
This atlas is dedicated specifically to gynecologic frozen section diagnosis and addresses professional practice gaps such as high diagnostic error rate, slow turnaround time, and inefficient communication between surgeons and pathologists at the time of intraoperative frozen section consultation of gynecologic specimens. The format of the volume is a combination of concise text and high quality gross and frozen section microscopic images, meticulously selected from the superb collection of pathology specimens of gynecologic tumors provided at Yale-New Haven Hospital in the past decades. Frequent entities with diagnostic pitfalls are balanced with less common lesions. Strategies to recognize their diagnostic features are emphasized, in addition to the impact on optimal surgical treatment of patients with gynecologic cancer. The indications, limitations, morphologic diagnostic criteria and pitfalls of frozen section consultation in gynecologic pathology are thoroughly reviewed with an ultimate goal of avoiding patient mismanagement in real-time. High quality frozen section microscopic illustrations aid the recognition of morphologic patterns and serve as quick reference during intraoperative consultation. Written by experts in the field, Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology is a valuable resource for pathologists at all career/expertise levels who are involved in intraoperative consultation in their daily clinical practice.
Environmentally Safe Strategies for Plant Protection Against Biotic and Abiotic Stresses
Environmentally Safe Strategies for Plant Protection Against Biotic and Abiotic Stresses presents environmentally friendly and safe methods for plant protection against not only biotic stresses caused by various pathogens and pests, but also against abiotic stresses such as salinity, drought, UV radiations, flood, unfavorable temperature, and pH, etc. The book aims to present approaches for both abiotic and biotic stresses, providing a valuable, integrated view to inspire new research as well as to implement and develop new practices. As global demand for organic food and feed products increases, it is necessary to focus on research areas related to discovery, application and demonstrating the modes of action of natural compounds obtained from various plants or mushrooms, as well as beneficial microbes and their metabolites involved in plant protection against biotic and abiotic stresses. These natural compounds, biocontrol agents and their volatile or non-volatile metabolites, which might have direct antagonism against phytopathogens and pests or indirect effect via induction of plant defense, could be formulated and used with high durability to control various environmental stresses in an eco-friendly manner.
Neuroimaging - From Research to Clinical Practice
Neuroimaging has transitioned from the laboratory to the clinic at an unprecedented pace, becoming a standard diagnostic, monitoring, and treatment tool for neurological and psychiatric diseases. In this book, a clear description of this revolution is provided, emphasizing how novel imaging techniques are reshaping contemporary medicine. Organized into three sections, the book opens with the examination of brain development, describing how state-of-the-art diffusion MRI reveals the dynamic architecture of the developing brain. The opening chapter emphasizes the promise of early imaging in identifying neurodevelopmental disorders. The second section is dedicated to clinical applications. Chapters cover the correspondence between neuroimaging features and disease, the use of nuclear medicine methodology in dementia, epilepsy, and movement disorders, and the diagnostic value of PET/CT, illustrated by case-based examples. These chapters offer practical insights into enhanced diagnostic accuracy and therapeutic support through multimodal imaging. The third section of the book acquaints readers with interventional and surgical applications. This section illustrates how imaging today is directly applied in therapy, from treatment under imaging guidance to neuronavigation and neuromodulation interventions. Trends for the future, such as the incorporation of AI, portable imaging, and augmented reality into the operating room, are also discussed. Authored by international experts, this book is intended for clinicians, researchers, and students interested in the clinical applications of neuroimaging. It links current research with everyday medical practice using case-based examples and practical frameworks. Neuroimaging - From Research to Clinical Practice is a reference and a guide to how brain imaging shapes modern treatment approaches.
Advances In Cancer Research
Cancer represents one of the most complex and challenging health burdens of our time, affecting millions of individuals globally and spanning virtually every tissue and organ system in the human body. At its core, cancer is fundamentally a disease of cellular dysregulation where normal checks and balances on cell growth, division, and death become compromised, leading to uncontrolled proliferation and, in many cases, metastatic spread. This chapter explores the foundational principles underlying cancer biology, setting the stage for understanding current therapeutic approaches and future innovations in cancer treatment and prevention.
Foundations and Innovations in Clinical Research and Trials
The book Essentials of Clinical Research and Trials offers a concise yet comprehensive guide to the multifaceted field of clinical research. It emphasizes the importance of multidisciplinary collaboration, adherence to ethical and regulatory standards, and the integration of advanced technologies to streamline processes and improve outcomes.Designed for both beginners and seasoned professionals, the book provides practical insights into trial design, execution, and analysis, with a strong focus on global accreditation standards, including NABH, WHO, and ICH-GCP.By incorporating perspectives from diverse departments-such as pharmacology, radiology, ethics committees, and data management-the book highlights the collaborative nature of clinical trials. This comprehensive approach ensures that readers gain a holistic understanding of the field, enabling them to address contemporary challenges and contribute meaningfully to medical advancements.
Diagnostic Imaging: Gastrointestinal
Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Gastrointestinal, Fifth Edition, is an invaluable resource for gastrointestinal radiologists, general radiologists, and trainees?anyone who requires an easily accessible, highly visual reference on today's GI imaging. Drs. Atif Zaheer, Siva P. Raman, and their team of highly regarded experts provide updated information on recent advances in technology and the understanding of GI diseases and disorders to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice.Serves as a one-stop resource for key concepts and information on GI imaging, including a wealth of new material and content updates throughoutCovers all aspects of GI imaging, including pathophysiology, imaging findings, and disease management options, such as the radiologist's role in evaluating patients for bariatric surgery, antireflux procedures, esophageal and bowel resections, and moreFeatures 3,300 high-quality print images (with an additional 2,100 images in the complimentary eBook), including radiology images, detailed medical illustrations, clinical photographs, and histology and gross pathology imagesFeatures updates from cover to cover, including new information on rectal MR, pelvic floor MR, and MR elastography; updated CT protocols; updated differential diagnoses; new cases and images; and new staging details and diagramsContains a variety of new chapters, including Approach to Incidental Lymph Nodes on CT/MR: Summary of 2013 ACR Consensus Statement; Approach to Management of Incidental Splenic Lesions: Summary of 2013 ACR Consensus; Management of Incidental Gallbladder and Biliary Findings: Summary of Consensus Statements; Management of Incidental Liver Lesions; Management of Pancreatic Cysts (with new guidelines); Summary of C-RADS for CT Colonography; and Summary of CT/MR LI-RADS 2018Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of careIncludes an eBook that allows you access to everything in the print version as well as additional images, text, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
Innovations and Implications in Molecular Diagnostics
This book introduces the field of molecular diagnostics, tracing its evolution from the earliest days of genetic research to cutting-edge advancements. It begins with a historical overview, setting the stage for an understanding of the foundational principles and techniques that underpin current practices in DNA analysis. It also provides the intricate details of various molecular techniques, such as advanced polymerase chain reaction (PCR) methods and next-generation sequencing, and their impact in the field of genetics and diagnostics. The book also explores the significant role of bioinformatics as the backbone of modern diagnostics and examines the changes brought about by high-throughput technologies and nanotechnology in molecular research and diagnostics. The importance of molecular imaging techniques in visualizing biological processes is discussed, along with the advancements in RNA analysis and their diagnostic implications. The book addresses the emerging fields of metabolomics and proteomics in molecular diagnostics and the transformative impact of artificial intelligence in this field. The book concludes with a thoughtful discussion on the ethical and regulatory considerations in molecular diagnostics. This book is intended for researchers and students of the fields of molecular diagnostics, biotechnology, and genomics.Key Features: Provides historical overview and recent advancements in the field of molecular diagnostics Explores foundational principles and advanced techniques in DNA analysis, including detailed insights into PCR methods Covers the applications and impact of next-generation sequencing in genetics and diagnostics Discusses the revolutionary influence of high-throughput technologies and nanotechnology in molecular research and diagnostics Examines the roles of metabolomics, proteomics, and artificial intelligence in molecular diagnostics
Elastography - Current Insights and Applications
The book Elastography - Current Insights and Applications aims to consolidate specific information and updates about elastography in general and abdominal pathologies specifically. The concept of elastography has been most widely explored for assessing liver fibrosis. However, multiple other domains, including focal liver lesions, endoscopic ultrasound elastography, and pancreatic elastography, are less explored. The book covers key concepts of bioethical principles, techniques, and recent updates on such areas of elastography in abdominal pathologies. We hope this book helps to enlighten the readers about these aspects of elastography.
Palliative Medicine and Hospice Care for Physician Associates Specialty Review
Palliative Medicine and Hospice Care for Physician Associates Specialty Review is a comprehensive review and guide for PAs who wish to study and practice for the Certificate of Added Qualification (CAQ) in Palliative Medicine and Hospice Care. It features 215 questions with multiple-choice answers across 11 chapters that are organized into three sections: Essential Aspects of Serious Illness Patient Care, Managing Suffering and Distress, and Care Transitions, Including End-of-Life. The fourth and last section, "Practice Essentials," contains two unique chapters on Hospice Essentials and Communication Essentials. These two chapters reinforce the two most fundamental facts of the PA profession: that PAs are trained in the fundamental skills of compassionate and attentive listening, and that they are lifelong learners in clinical medicine. Both chapters address topics that are not part of the blueprint for the CAQ but are nonetheless essential to the professional practice of a PA who is employed by hospice or interacts with any part of hospice in the world of palliative medicine. Each item featured in the book contains a case study in the question stem, followed by a discussion of the multiple choices that addresses why one option is correct while the others are not. This rich clinical material can enhance the knowledge and understanding of not just PAs training for the CAQ, but any physician or allied health professional involved in palliative medicine and hospice.
When Your Neurons Dance
As an Emergency Medicine consultant in one of the busiest departments in the UK, Dr Jonny Acheson loved his job. Fuelled by adrenaline, he treated and cared for some of the sickest patients who came through the doors.In 2016, when he was 41, he was diagnosed with Parkinson's, a progressive neurological condition for which there is no cure.He found it increasingly difficult to multitask in his fast-paced world. The environment that he thrived in made his symptoms worse. Parkinson's challenged his professional identity as an emergency doctor, and he didn't know what to do.When Your Neurons Dance is about how he is adapting over time with support around him - how he looked to the past to help him in the present, embracing change as new doors opened both inside and outside medicine.Ultimately as a doctor practising with Parkinson's, he found a way to give back, despite a condition that always takes away.
When Your Neurons Dance
As an Emergency Medicine consultant in one of the busiest departments in the UK, Dr Jonny Acheson loved his job. Fuelled by adrenaline, he treated and cared for some of the sickest patients who came through the doors.In 2016, when he was 41, he was diagnosed with Parkinson's, a progressive neurological condition for which there is no cure.He found it increasingly difficult to multitask in his fast-paced world. The environment that he thrived in made his symptoms worse. Parkinson's challenged his professional identity as an emergency doctor, and he didn't know what to do.When Your Neurons Dance is about how he is adapting over time with support around him - how he looked to the past to help him in the present, embracing change as new doors opened both inside and outside medicine.Ultimately as a doctor practising with Parkinson's, he found a way to give back, despite a condition that always takes away.
Immunohistochemistry and Ancillary Studies in Diagnostic Dermatopathology
Immunohistochemistry and ancillary studies play a crucial role in diagnostic pathology. Yet, few books cover their practicality in diagnostic dermatopathology. This book provides a practical guide to the application of rapid and cost-effective immunohistochemistry, as well as ancillary studies including immunofluorescence and molecular studies. With a focus on practicality and bridging knowledge gaps, the book covers helpful diagnostic stains and pertinent ancillary studies, organized by lines of differentiation. Each chapter includes a synopsis of antibodies, immunohistochemical panels, summary tables outlining staining patterns, and case studies. Now in its second edition, this book covers entities based on lineage, including epithelial, adnexal, melanocytic, lymphoid, and soft tissue, and discusses the role of molecular studies in the diagnosis of cutaneous neoplasms and soft tissue lesions. This comprehensive volume is an essential resource for pathologists, dermatopathologists, and residents in pathology and dermatology.