Clinical Treatises on the Pathology and Therapy of Disorders of Metabolism and Nutrition; v.6
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Regulations and Orders
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Brief History of the Warneford Lunatic Asylum
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A Practical Treatise on the Function and Diseases of the Unimpregnated Womb
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Selenium Derivatives of Bicyclic Compounds as Potential Cancer Therapeutic Agents.
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Clinical Disorders of the Heart Beat
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The Journal of Cutaneous Diseases Including Syphilis; 35
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?ber Die Psychologie Der Dementia Praecox
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Practical Observations on Cancerous Complaints
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First Principles of Otology; a Text-book for Medical Students
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Womanhood
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Pathology and Treatment of Ringworm [electronic Resource]
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Practical Observations on Insanity
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Dermatologic Medications
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Summary of Available Knowledge Concerning Skin Friction and Heat Transfer and Its Application to the Design of High-speed Missiles
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Studies in Bibliography; 39
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Diseases of the Heart; Their Pathology, Diagnosis and Treatment
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Eczema With an Analysis of Eight Thousand Cases of the Disease
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Psychoanalytic Psychiatry and Psychology; Clinical and Theoretical Papers; 1
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The Biology of Mental Defect
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Archaeology and Society; Reconstructing the Prehistoric Past
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Studies in Bibliography; 32
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A Letter to Jimmy
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Dermatologic Medications
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What Asylums Were, Are, and Ought to Be, Being the Substance of Five Lectures Delivered Before the Managers of the Montrose Royal Lunatic Asylum; c.2
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The Anatomical and Histological Dissection of the Human Ear
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Spinal Disease and Spinal Curvature
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Lithium Therapy
Lithium is a first choice mood-stabilizer for the maintenance treatment of bipolar disorder. The drug can augment antidepressants in treatment-resistant depression and exerts anti-suicidal, immunomodulatory, and neuroprotective action. For the author of this book, clinical use and mechanism of therapeutic action of lithium have been a leitmotiv since 1970. It resulted in multiple publications, and the book "Lithium - the amazing drug in psychiatry", published in 2020. Thirty-nine papers from the recent decade were selected here, in all of them Prof. Rybakowski is the first or the last author. The editorial in Neuropsychobiology on the 60th anniversary of lithium entering modern psychiatry is followed by the 2010 update on lithium in neuropsychiatry. The studies of an association between lithium efficacy and temperament as well as candidate genes are presented. The effects of lithium on cognitive, kidney, and thyroid functions were covered in many articles. The studies on lithium's biochemical mechanism with very small embryonic-like stem cells and mRNA of neuronal and glial markers are shown.Ultra-long-term therapy with lithium is described in five patients receiving lithium for more than 40 years, and in another paper, presenting a patient on lithium for half a century. Given the clinical and biological properties of lithium, this drug is presently greatly underutilized and efforts should be undertaken for challenging lithium's skepticism and optimizing its long-term administration. Such a message was expressed in a special paper published in 2018 and in several "state of the art" papers on lithium in 2020. About the Author: Prof. Janusz K. Rybakowski was the Head, Department of Adult Psychiatry, Poznan University of Medical Sciences, 1995-2016, the Chairman, Department of Psychiatry, Medical Academy, Bydgoszcz, 1985-1995, the NIH Fogarty Research Fellow, University of Pennsylvania, Philadelphia, 1976-1977. He was the President of the Polish Psychiatric Association, 1998-2001. Authored over 700 scientific articles, Hirsch Index 56, and the books "The Faces of Manic-Depressive Illness" (2009) and "Lithium - the Amazing Drug in Psychiatry" (2020). A member of the Editorial Board of 16 international journals. In 2012, received the Lifetime Achievement Award of the European Bipolar Forum, in 2015, the Lifetime Achievement Award in Biological Psychiatry of the World Federation of the Societies of Biological Psychiatry, and 2018, the Mogens Schou scientific award of the International Society of Bipolar Disorders.
Autophagy in tumor and tumor microenvironment
This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy's role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers avaluable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
Breast Cancer: An Issue of Oncology Clinics
Breast cancer is a malign tumor that commonly infests the female population. It may be associated with a variety of causes such as lack of physical exercise, hormone replacement surgery, obesity, alcohol, early age menstruation, etc. Breast cancer can be diagnosed with the help of biopsy and mammographic screening and treatments include radiation therapy, surgery, chemotherapy, targeted therapy and hormonal therapy. This book covers the diverse aspects related to breast cancer such as diagnosis, pathophysiology, management, risk factors, etc. Selected concepts, advancements and theories revolving around breast cancer and related issues have been presented in this book. Researchers, experts, doctors and students in this field will find this text extremely beneficial.
Principles and Practice of Dermatology
Dermatology deals with the diagnosis and treatment of skin disorders. Skin is the largest organ of body and functions as a cover for internal organs. Due to this it is vulnerable to the damaging effects of pollutants, irritants, ultraviolet and infrared rays, pathogens, etc. It plays an important role in regulating the temperature of the body. The diseases treated under this field of medical science are fungal infections, dermatitis, psoriasis, skin cancer, warts, cold sores, ectopic eczema, etc. This book is compiled in such a manner, that it will provide in-depth knowledge about the theory and practice of dermatology. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of dermatology. It is a beneficial source of knowledge offering the readers new and valuable insights into this discipline. This book is an essential guide for dermatologists, academicians and those who wish to pursue this discipline further.
A Clinician's Guide to Otolaryngology
Otolaryngology is a field of medical science that deals with the diagnosis and treatment of disorders related to ear, neck, throat (ENT) and base of skull. This field examines the problems in the ENT region and treats them with the help of surgery and various medicines. This book discusses the various techniques and new advancements in this field. It will include contributions from experts and scientists which will provide in-depth knowledge of this subject. A number of researches and case studies from all over the globe have been included in this book which makes it a complete source of knowledge. Coherent flow of topics, reader friendly language and extensive examples make this is an invaluable reference source for those interested in this subject.
Thoracic Surgery for the Acute Care Surgeon
This volume is a "how-to guide" to treating thoracic trauma and emergencies for acute care surgeons. It highlights the diagnosis and management of thoracic disease and injuries, and each chapter includes algorithms that lead readers through the process of identifying and treating many common and some uncommon thoracic pathologies. The international team of authors provides readers with a unique and diverse approach to the operative and non-operative challenges encountered by ACS surgeons. The large number of figures offers readers insights into what they can expect to see when caring for these patients. The editors understand that the management of adults and children differ and have included a specific chapter on pediatrics. Given the broad audience and diverse settings in which the text can be used, the authors also provide details of care in limited-resource environments. The volume is a valuable tool for professionals interested in thoracic surgery and acute care surgery.
Dimensions of Psychological Problems
A remarkable and extremely important ongoing positive revolution in how we think about psychological problems is rapidly reaching a tipping point. This book provides a manifesto for this revolution. An increasing number of psychologists and psychiatrists are proposing that we either radically change the next edition of the Diagnostic and Statistical Manual of the Mental Disorders and the International Classification of Diseases or leave them behind entirely. The author argues for a view of psychological problems that is far less stigmatizing and better supported by the data but which will require large changes in thinking. First, there is no clear distinction between "normal" and "abnormal" psychological functioning. Psychological problems do not reflect rare and terrifying "illnesses" of the mind, but are problematic ways of thinking, feeling, and behaving that lie on continuous dimensions from minor to severe. Crucially, psychological problems are ordinary aspects of the human experience. They are ordinary in the sense of being commonplace-the great majority of us will experience distressing and disruptive psychological problems at some time during our lives-and are ordinary in arising through the same natural interplay of genetic and environmental influences as any other aspect of behavior. The dimensions of psychological problems are highly correlated and these correlations provide vital clues as that allow us to see a hierarchy of causes of psychological problems for the first time. These range from factors that influence the likelihood of exhibiting some kind of psychological problem, but not which kind, to highly specific causes.
Gastroesophageal Reflux Disease: An Overview
An overview of the gastroesophageal reflux disease has been provided in this book. Gastroesophageal Reflux Disease (GERD) has been a major concern for many people who are affected by this disease. People affected by GERD live under a constant threat of deteriorating quality of life and also, a latent risk of becoming cancer infected. Furthermore, it has been a financial burden for both the diseased and the society. This book aims at providing the gastroenterologists, with an insight into GERD, and helping them to manage and combat this severe disease.
Selected Topics in Neuroendocrinology
The aim of this book is to present significant topics in neuroendocrinology. The comprehension of the neuroendocrine system presents an insight into a broad spectrum of bodily and mental processes. This book serves as a brief guide encompassing updated information regarding the function of the endocrine glands and organs in relation with neuropeptides, neurotransmitters, and behavioral manifestations. Several distinct forms of stress response, for example cognitive changes and anxiety, have been intrinsic to other species as well as to us. These mechanisms particularly involve intricate interactions among emotional, behavioral and physical processes in human beings. This book presents information regarding peptide hormones, i.e. vasopressin and oxytocin, and how analyses of these neuropeptides enhance our comprehension of social and other behaviors along with information regarding the impacts of these neuromodulators on sexual behavior and water balance in the body.
Managing Uncertainty in Mental Health Care
As the profound contribution of mental illness to disability, morbidity, and mortality has gained acceptance, mental health has grown into a global priority. One in five experience mental illness in their lifetime, and those who suffer are coming forward in unprecedented numbers. As more people seek care for themselves and others, providers are increasingly unable to meet the demand through existing systems and mental health care approaches. In Managing Uncertainty in Mental Health Care, Drs. Patricia Rockman and Jos矇 Silveira critically examine core assumptions informing the primary approaches currently used to assess mental illness in clinical settings, with an emphasis on clinician certainty. They illustrate how current diagnostic frameworks obscure clinician uncertainty while encouraging overconfidence and go on to consider potential strategies for lessening the impact of inevitable errors. Ultimately, this book makes a case for acknowledging the fallibility of clinical judgment, independent of competence and experience, and the need to modify approaches to mental health care so that they align with the irreducible uncertainty of the domain. By exploring emerging transdiagnostic approaches to mental health care in terms of their alignment with irreducible uncertainty, Rockman and Silveira make space for error and offer clinicians a novel way to advance the fundamental aim of mental health care: to reduce the harm and suffering of all.
Carcinogen: Case Studies and Reviews
This book aims to provide an overview of carcinogens. In the past few years, there has been an increase in cancer cases all over the world. Low food quality and increased pollution of the environment are the primary reasons for carcinogenesis. The main difficulty for experts is to find approaches for the prevention of cancer disorders. Hence, knowledge about the models for analyzing carcinogenesis and mutagens which emerge during cooking, ecological pollutants, and tests for precise discovery of carcinogens is extremely significant. This book intends to provide some useful information for experts and students in accomplishing their respective researches.
Neuropathic Pain
Neuropathic pain is a pain associated with nerves. The intensity of this is dependent on the austerity, pain threshold and the sufferer's ability to cope. Despite trying to treat neuropathic pain with mono-therapy or their combinations, it may not be resolved completely. Therefore, the patient's consent and understanding is required for its management. Knowledge and patient's awareness as an objective may be helpful during therapies for neuropathic pain. The book acknowledges the contribution of its makers and includes the introduction, characteristics, treatment and randomized interventions to particular management of neuropathic pain.
Significant Developments in Infective Endocarditis
The most significant developments in the field of infective endocarditis are elucidated in this profound book. Endocarditis is an inflammation of the lining of valves and the heart. It can result from a non-infectious cause as well but when the inflammation is related to an infection, usually bacterial, it is termed as infective endocarditis. It normally involves the formation of a large septic thrombus on one of the cardiac valves. As this thrombus develops, it can lead to valve failure or may fragment forming a septic embolus associated with high mortality in cases where the target of the embolus is the brain, heart or lung. This book provides insights into multi-organ complications related to infective endocarditis including latest developments in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery.
Integrated Approach to Renal Cell Carcinoma
An integrated approach to renal cell carcinoma has been presented in this all-inclusive book. The field of renal cell cancer has evolved significantly. This book compiles latest research and innovative ideas for the future in this fast evolving field, including surgery, pathology, radiation oncology, supportive care, basic science, medicine and radiology. It deals with a number of topics including surgery procedures, tumor biology, radiation therapy and molecular biology. It also discusses present and future treatments of the diseases that are on the horizon. The book provides comprehensive knowledge and interpretation of this field for scientists and clinicians as well for assisting trainees in medicine, surgery and pathology.
Celiac Disease: Recent Advances
This book, written by renowned experts, comprises advanced studies and researches concerning Celiac Disease (CD). CD is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains in genetically vulnerable people. CD can manifest itself with a formerly unacknowledged variety of clinical symptoms, inclusive of the usual malabsorption syndrome and a range of symptoms potentially disturbing any organ structure. As CD often manifests itself in an uncommon manner, many cases remain undiagnosed and carry the risk of long-term difficulties, including anemia and other hematological disorders, neurological disorders or cancer. The pervasiveness of the disorder and its range of clinical outcomes pose a number of questions. This book presents answers to these questions by compiling researches conducted by prominent experts in this field.
Recent Developments in Peripheral Neuropathy: Mechanism and Management
Peripheral neuropathy (PN) is defined as a damage or disease that affects the nerves. It is a necessary practice for practitioners to remain well-versed with rapid advances in the assessment and management of peripheral neuropathies as well as the complexity of their mechanism, for enhancement of patient care. The aim of this book is to acquaint health care professionals with current developments in the treatment, diagnosis and pathogenesis of peripheral neuropathy. Clinicians as well as scientists with great expertise in the field have contributed in this book.
Encyclopedia of Kidney Diseases
This book presents latest insights into kidney diseases. It discusses topics like cerebral-renal salt wasting, congenital obstructive nephropathy, and the role of hemoglobin variability in clinical results of chronic kidney disease which are not generally available in other books. The book is a compilation of informative reviews contributed by renowned clinicians and scientists in the field, which collectively would serve as a valuable tool for nephrologists.
Handbook of Germ Cell Tumors
This is an up-to-date book designed to educate the readers about germ cell tumors. It presents a context of latest information related to germ cell tumors. It deals with clinical representations, regime models, the biology and genetics of the germ cell tumors in children and adults. The book focuses on testicular germ cell tumors whose rate has grown in young males. It also includes analysis on the pathogenesis, risk factors, diagnosis and treatment regimens applied to precursor, pre-invasive lesions and to seminomatous and non-seminomatous germ cell tumors of the testes. The book also sheds light on the diagnosis and contemporary management options for intracranial germ cell tumors in children. There is also discussion related to the genetics and epigenetics of germ cell tumor growth in humans and in the mouse model system. This book will be beneficial to researchers, physicians and readers who want to gain knowledge about germ cell tumors.
Rectum and Colon: Endoscopic Procedures
This book provides a descriptive account of the endoscopic procedures related to rectum and colon. It commences with basic topics like screening by colonoscopy, and preparation and monitoring for this test. In addition to these approaches, the book discusses endoscopic diagnostic and therapeutic aspects in the colon and rectum. The description of each topic is very comprehensive, instructive and coherent. This book targets general and colorectal surgeons as it presents guidelines for diagnosis and treatment which are very well established.
Diabetic Nephropathy
This book includes research by internationally renowned experts. They discuss the comparative usefulness of their work in relation to diabetic nephropathy. The book elucidates the new role of oxidative stress in the development of diabetic nephropathy and intrarenal renin-angiotensin-aldosterone system (RAAS) and presents the latest pharmacological interventions in the treatment of diabetic nephropathy. It highlights other significant contributions outside of the RAAS in the pathogenesis of diabetic nephropathy including epithelial-mesenchymal-transition (EMT), immune cytokines and AGE/RAGE and also presents latest information on several pathophysiological determinants in the development of diabetic nephropathy. Lastly, recent information on numerous distinct pharmacological interventions of diabetic nephropathy is also included.
Current Concepts in Urology
This book is an extensive source of information for research in the field of urology. The spectrum of possibilities for urology is growing in leaps and bounds to emerge as the most rapidly expanding surgical superspecialty. This rapid growth over the past
