Therapeutic Potential of Natural Products in Internal Diseases
Effects of Plant Extracts on Human Health
Plant extracts exhibit a variety of bioactive compounds (polyphenols, carotenoids, fibers, essential oils, polysaccharides, alkaloids, and proteins). The majority have biological effects, but their mechanisms of action are still unknown. In fact, the variability of compounds in crude extract of plants poses a challenge to fish, and exhibit activity for selected cellular targets for specific diseases of interest. This Special Issue focuses on medicinal plants and explores the potential effect of extracts and/or its compounds sourced from medicinal plants in specific experimental models of diseases. This SI summarizes the updated data related to plant extracts, and in some cases, highlighted major compounds characterized from a specific extract/plant in different disease models, including in cell-line prostate cancer and C57BL/6 mouse prostate, rheumatoid arthritis, respiratory diseases, hyperuricemia, hearing loss, influenza A, thrombose, and diabetes. In addition, there have been reports about the multifaceted effects of extracts on inflammation, neuroprotection, immunomodulation, hepatoprotection, cardio protection, diabetes, and arthritic and microbial stress. Therefore, we invite readers who are passionate about this topic to read this Special Issue.
Tuning in to Alex
Follow Alex's journey with Auditory Processing Disorder (APD) and learn how he thrives with the right support using simple, effective strategies.This heart-warming, beautifully illustrated children's book-created in collaboration with Dr. Angela Alexander and illustrated by Bridget Acreman-introduces young readers to APD, a neurological condition where the brain has difficulty interpreting sounds, especially speech.Through Alex's experiences, children learn that everyday challenges can be overcome with support and creativity.Written in clear, child-friendly language, Tuning in to Alex helps children with auditory or sensory processing difficulty feel understood and empowered.It also guides parents, caregivers, educators, and peers in creating a calm and more inclusive, empathetic environment.Filled with practical examples and conversation starters, this book is ideal for: families navigating an APD diagnosisteachers supporting diverse learnersaudiologists, speech pathologists, occupational therapists and allied health professionalsclassrooms and friendship groups, encouraging empathy and inclusion.Tuning in to Alex promotes neurodiversity, emotional literacy, resilience and the importance of the right support making a world of difference-making it an essential resource for anyone supporting children with invisible disability, learning or neurological condition.A beautifully layered children's story that speaks to both kids and adults, offering a fresh and affirming take on identity, inclusion, and self-understanding. Perfect for children aged 5-10 and the grown-ups in their lives.
The 9-to-5 Body
Stiff shoulders, tight hips, and drained energy don't have to be the cost of a desk job. The truth is that the 9-to-5 doesn't just shape your schedule-it shapes your body, your posture, and even your stress levels. Yet the solution isn't squeezing in more gym time or buying expensive gadgets. The key is learning how to turn your workday itself into a powerful engine of mobility, strength, and focus. This book delivers practical, science-based strategies that show how to reverse the hidden toll of office life through simple, precise practices woven directly into the flow of your day. Whether you're dealing with aching joints, mid-afternoon crashes, or the creeping slump of poor posture, you'll discover how to reclaim energy and resilience without stepping away from your career. Inside, you'll find: - Desk workout routines that build strength and stability in minutes, not hours - Smart mobility exercises for desk jobs that restore hips and shoulders without disrupting workflow - Proven posture correction at desk strategies that align your body naturally, not through willpower alone - Ergonomic tips for home office setups that truly protect, rather than just look impressive - Tools for cortisol management at work to lower stress and sharpen focus throughout the day - Quick "movement snacks during workday" that keep stiffness from ever setting in Designed for busy professionals, remote workers, and anyone caught in the trap of constant sitting, this is not about chasing perfection or adding hours to your routine. It's about building a clear system-a workday fitness plan-that helps you stay strong, mobile, and energized while you work. By the end, you'll have the clarity and confidence to transform the way you move, feel, and perform-right from your desk.
Melanoma
This Reprint comprises eight published papers, covering aspects of the molecular pathology of, and therapeutic approaches to melanoma. Topics covered in the Reprint include therapeutic approaches to treat melanoma, mechanisms of therapeutic resistance and approaches to address therapeutic resistance in melanoma, immune-related pathways and microenvironmental factors that impact melanoma pathobiology, and genomic as well as epigenomic mechanisms involved in melanoma pathobiology or treatment response.
Environmental Contaminants and Human Health
Environmental contaminants and related human health risks have become a global environmental issue. Environmental contaminants enter the ecosystem and are enriched by the food chain. Potential exposure to humans has been a concern for society as a whole. In recent years, there has been growing interest in the relationship between environmental contaminants and human diseases, trying to answer the question of how the contaminants affect human bodies. Therefore, this Special Issue focuses on environmental contaminants and human health, aiming to figure out the relationship and mechanism. Therefore, it covers but is not limited to the following topics: the occurrence levels of contaminants in environmental and human bodies, exposure estimation, toxicity research, meta-analyses, and data reviews.
Straight Talk about Looking Your Best
Is there something about your appearance that makes you unhappy? Does it bother you every day, or only once in a while? Considering aesthetic treatments or plastic surgery can feel overwhelming-even intimidating. Yet, every year, hundreds of thousands of people undergo procedures to enhance their appearance and boost their confidence. But where do you start?With over 35 years of experience and more than 10,000 aesthetic and plastic surgeries performed, Dr. Thomas J. Francel, MD, FACS, offers expert advice to help you navigate the world of aesthetic procedures with confidence. Before stepping into a consultation, arm yourself with insider knowledge to maximize your time, avoid unnecessary expenses, and ensure you make informed decisions.Let Dr. Francel be your guide--turn what could be a frustrating and costly experience into an empowering, fulfilling journey toward the best version of yourself!
Diabetes
Diabetes is one of the most challenging health problems in the 21st century, projected to affect 700 million people by 2045. In the last 15 years, the number of people diagnosed with type 1 diabetes increased by 45%, and those diagnosed with type 2 diabetes increased by 95%. The most devastating effects of diabetes are its chronic complications, which confer a high risk of morbidity and mortality and an increased health system cost burden. Although there is increased awareness and new therapeutic options in the treatment of diabetes, it is still the leading cause of blindness in working-age adults, the leading cause of kidney failure and dialysis, and the leading cause of nontraumatic lower-limb amputations.This Special Issue, featuring thirteen research articles, three reviews, and one systematic review, presents the latest knowledge of diabetes and its complications. Topics include the connection between circulating isthmin-1 levels and diabetes, material technologies for improved diabetic foot ulcer treatment, depression and stress in type 2 diabetes, metformin in gestational diabetes, safety of semaglutide and tirzepatide in type 2 diabetes, and aging-related biomarkers in diabetic nephropathy. The Special Issue also explores associations between serum cytokines and growth factors with time in range, as well as progression of diabetic kidney disease and gastrointestinal symptoms in subjects with type 1 diabetes.This new knowledge promises to enhance diagnosis, reduce the rate of progression of diabetes-related chronic complications, and may form the basis for future therapeutic approaches.
New Updates in Oral and Maxillofacial Surgery
In recent years, with the rapid development of medical equipment, surgical techniques, and biomaterials, the field of oral and maxillofacial surgery has progressed to providing digital and personalized treatments. This includes digital imaging, digital impressions, jaw modeling, 3D planning of complex oral prosthetics, osteophytes and implant placement, and minimally invasive surgery, such as endoscopic and functional surgery. This Reprint, entitled "New Updates in Oral and Maxillofacial Surgery", aims to discuss personalized treatment and future trends in oral and maxillofacial surgery. A variety of topics are discussed, including the following: Orthognathic surgery and surgical treatment/correction of dental and maxillofacial malformations;Head and neck cosmetic surgery;Oral cancer;Reconstructive surgery;Management of oral diseases;New methods and techniques in oral and maxillofacial surgery;Oral and maxillofacial soft and hard tissue trauma and reconstruction techniques;Drug-related osteonecrosis of the jaw;New diagnostic and therapeutic tools for the management of potentially malignant diseases of the oral cavity.
Worship in a Time of Pandemic
This Special Issue Reprint addresses the challenges and possibilities that Christian liturgies faced during the recent global pandemic. These challenges and possibilities are discussed from theological, historical, and practical perspectives. The authors of the nine studies range across a variety of Christian denominations and areas, from the U.S. to Venezuela to Korea, and address a variety of issues, from liturgical time to worship music to spiritual communion.
Cutting-Edge Research on Physical Fitness Profile in Soccer Players
Ethics, Social Responsibility and Quality of Life in Times of Crisis
Public Health Consequences of Social Isolation and Loneliness
Nursing as Caring
Nursing as Caring: A Model for Transforming Practice presents a profound and transformative approach to nursing, emphasizing care as the fundamental core of the profession. Developed by Anne Boykin and Savina O'Bryan Schoenhofer, this influential model redefines nursing as a discipline rooted in human connection, respect, and shared values, shifting the focus from tasks and procedures to authentic caring relationships.The authors describe caring as an innate human quality and position nursing as the professional expression of that caring in practical, meaningful ways. Through philosophical grounding, theoretical explanation, and real-world applications, the book demonstrates how nurses can create healing environments, honor personhood, and cultivate deeper patient-nurse partnerships.This essential work is widely embraced in nursing education and practice for its clarity, depth, and human-centered perspective. Ideal for nursing students, educators, practitioners, and leaders seeking a more compassionate, holistic, and person-focused model of care, Nursing as Caring offers an inspiring vision for the future of the nursing profession.
Disease Control Priorities, Fourth Edition (Volume 2)
The fourth edition of Disease Control Priorities (DCP) builds on the three previous editions published from 1993 through 2018. DCP4 uses a collaborative, country-led approach to summarize, produce, and help translate economic evidence to inform better priority setting and capacity strengthening for universal health coverage, public health functions, pandemic preparedness and response, and intersectoral and international action for health. New modeling for DCP4 suggests more than a 20 percent probability in the next decade of another pandemic with mortality comparable to COVID-19. Volume 2, Investing in Pandemic Prevention, Preparedness, and Response, provides practical guidance for countries to prevent, prepare for, and respond to pandemics. Drawing on COVID-19 lessons, it identifies key priorities to build resilient systems that protect lives and economies through evidence-based national and regional actions. Early chapters focus on prevention-- reducing zoonotic risks, strengthening biosafety measures, improving early detection systems, and rapidly characterizing and containing outbreaks. Other chapters discuss targeted public health measures and broader public health and social measures to curb transmission. Core health system investments receive particular attention, especially oxygen systems, emergency care, and vaccine delivery infrastructure that serve both routine and pandemic needs. Later chapters address medical countermeasures, proposing prearranged financing and decentralized manufacturing to accelerate deployment and reduce disparities. Finally, the volume presents a comprehensive framework for pandemic financing that spans the entire pandemic cycle, emphasizing the need for timely, adequate, and effective financial resources. The framework is designed to support policy makers in countries at all income levels and provides a guide to appropriate financing tools for each stage of a pandemic
Mitochondria
This Reprint brings together a curated selection of original research and review articles that explore the multifaceted roles of mitochondria in health and disease. It highlights mitochondria as dynamic organelles that extend far beyond energy production, acting as key regulators of cellular signaling, metabolic homeostasis, and stress responses. The collection spans a broad biomedical spectrum, from mitochondrial quality control in fertility and early-life programming to their dysfunction in chronic diseases such as cardiovascular disorders, liver pathologies, and neurodegenerative conditions. Special attention is given to sex-specific responses, developmental origins of mitochondrial health, and emerging therapeutic strategies targeting mitochondrial pathways. This Reprint provides a comprehensive and timely synthesis for researchers and clinicians who are interested in mitochondrial biology and its translational potential.
Data Driven Insights in Healthcare
This Reprint presents a collection of data-driven investigations that advance healthcare research beyond traditional theory-driven approaches. The articles featured in this collection demonstrate how observational experiences and big data analytics can uncover novel insights that improve healthcare practice and delivery.This Reprint showcases diverse methodologies for extracting value from healthcare data sets, including qualitative analysis of comments, data mining of large data sets, exploratory data techniques utilizing artificial intelligence and machine learning, and other innovative approaches to discovering patterns and relationships within complex healthcare data. Review articles examining the application and potential of data-driven approaches in healthcare are also included.The research compiled in this Reprint illustrates how data exploration generates new possibilities and enhances understanding of current theories and practices in healthcare. The studies employ various data analytic methods to reveal relationships among variables and provide actionable insights for healthcare researchers and practitioners. Collectively, these works demonstrate that discoveries emerging from systematic data exploration merit continued investigation and offer practical value for advancing healthcare delivery and outcomes.
Recent Advances in Understanding Systemic Sclerosis
Systemic sclerosis (SSc) is a complex, multifaceted autoimmune disease characterized by vascular abnormalities, immune system dysregulation, and progressive fibrosis of the skin and internal organs. Despite significant strides in understanding the pathogenesis of SSc, it remains a challenging condition to diagnose and manage due to its heterogeneity and its variability in clinical manifestations.We are pleased to provide a comprehensive overview of the current state of knowledge, treatment, and future perspectives of therapeutic approaches in this Special Issue.
Thyroid Disease
This Reprint presents novel developments in thyroid disease diagnosis and treatment, addressing both common and rare thyroid conditions. The collection emphasizes the evolution from traditional imaging-based assessments toward personalized, multi-parameter approaches that integrate patient demographics, molecular markers, and advanced technologies. Key contributions explore enhanced risk stratification methods for thyroid nodules, incorporating age, gender, and clinical variables alongside sonographic features to improve diagnostic precision. This Reprint examines shifting epidemiological patterns in thyroid cancer, revealing demographic changes and evolving disease presentations over the past two decades.Treatment innovations highlight refined radioiodine approaches for managing both benign goiter and differentiated thyroid cancer. Novel redifferentiation strategies targeting molecular pathways offer promising alternatives for patients with radioiodine-refractory disease. New developments in thyroid cancer biomarkers have resolved several longstanding analytical problems, with improved assays offering greater reliability and enhanced monitoring options. The Reprint also addresses specialized topics, encompassing pregnancy considerations in autoimmune thyroid disorders and surgical management strategies for uncommon conditions such as thyroid hormone resistance.
New Insights into Suicide and Mental Health Conditions
The Reprint entitled "New Insights into Suicide and Mental Health Conditions" gathers cutting-edge research focused on the underlying neurobiology, clinical interventions, and methodological innovations addressing suicide and suicidal behavior in the context of mental health disorders. Suicide remains among the most urgent public-health challenges worldwide, and many individuals who die by suicide have longstanding psychiatric disorders, and yet face limited access to effective interventions. This Reprint highlights contributions that advance our understanding of etiological mechanisms, identify novel therapeutic approaches-including brain-based and neurophysiological interventions-and develop rigorous trial designs for use in high-risk populations. The scope spans pharmacological and non-pharmacological interventions, brain stimulation techniques, digital and biomarker-driven risk prediction, psychometric instrument validation for suicidality screening across diverse settings, and contextual factors shaping implementation of evidence-supported strategies. With an emphasis on bridging translational neuroscience and clinical practice, this compilation aims to accelerate progress in preventing suicidal ideation and behavior and to improve outcomes for individuals affected by severe mental health conditions.
Unlocking Diagnosis Through Story and Touch
Basics of Physical Diagnosis: History Taking and Physical Examination is an essential guide for health science and medical students and senior practitioners to sharpen their history and diagnostic skills. It emphasizes the importance of observation, communication, and critical thinking in forming accurate diagnoses and building strong patient relationships. The book covers basic history-taking techniques using both systemic (medical) and functional approaches. It also includes assessment techniques for each body system, outlining the appropriate steps and highlighting the key anatomical landmarks relevant to each system.
Quality of Life After Surgically Treated Ankle Fractures
The general objective of this thesis was to evaluate and compare the functionality, pain and quality of life (QOL) of active and inactive adult individuals whose ankle fracture (AF) was surgically treated; and the specific objectives were: i) To conduct a systematic review evaluating functional outcomes and the QOL of patients with surgically treated AF compared with the nonfractured population; ii) To compare adult men and women residing in Brazil's interior who were treated with open reduction and internal fixation (ORIF) following AF; and iii) To describe and prospectively analyze unstable AF, surgically treated through ORIF, in adults in the Jequitinhonha Valley region of Brazil. Questionnaires such as the IPAQ, MMSE, SF-36, VAS, and sociodemographic and clinical questionnaires were administered. The morphology of the AFs was analyzed according to the AO Foundation and Orthopaedic Trauma Association (AO/OTA) classification system. Of the 86 patients, young men predominated in all variables studied. The most common cause of injury was motorcycle accidents, followed by soccer accidents (p
Effect of Zingiber Officinale Extract on Some Pharmacological Parameters in Rodentse
Ginger is a perennial plant that grows in India, China, Mexico and several other countries. The rhizome is used as both spice and in herbal medicine. Many studies have been done on pharmacological effect of ginger extract and our paper has been focused on cytoprotective effect of ginger on ethanol induced gastric injury in mice. Many drugs have been used in the treatment of peptic ulcer but each of them associated with different side effect so trends today toward use of herbal medicine which was associated with adverse effect. Ginger hydroalcoholic extract contain different consistent with anti-ulcer properties like 6-Gingersulfonic acid and three monoacyldigalactosyl glycerol including ginger glycolipid A. B. C .The mechanism of ginger extract may be due to counteracting the active oxidant radicals, decreasing mucosal cell shedding and thicking the mucus membrane so ginger extract has antiulcer properties when used in accurate dose and accurate duration. Keywords: Cytoprotective effect; Ethanol; Ginger hydroalcoholic extract; Mice; Zingiber Officinal
What Paramedics Should Know
What a Paramedic Should Know is a practical, experience-driven guide built for the realities of modern EMS. This book strips paramedicine down to what truly matters: sharp assessment, calm decision-making, mastery of equipment, and the ability to stay steady when everything around you is falling apart. It blends clinical science, field-tested judgment, and real-world scenarios into a clear and direct roadmap for the working medic.The book starts with foundational skills, including detailed explanations of airway control, respiratory assessment, and circulation management. Readers learn how to identify subtle clinical clues, recognize early signs of decompensation, and intervene before a patient's condition turns critical. Trauma care is presented with equal clarity, using ATLS principles to walk the reader through mechanism of injury, primary and secondary assessments, hidden injury patterns, treatment priorities, and the teamwork required during chaotic scenes. Every section emphasizes how to think, not just what to do.Advanced Life Support is given the depth it deserves. The text explores cardiac monitor interpretation, the physics and physiology of defibrillation, troubleshooting equipment failures, and rhythm recognition under pressure. Real call examples highlight how a single misread waveform can change the entire outcome. Airway management receives the same level of precision, with honest discussions about intubation challenges, cricothyrotomy considerations, and the importance of knowing your tools as well as your anatomy.Pediatric care is addressed with realism and compassion. Each age group is explained through developmental needs, physiological differences, and communication strategies that help reduce fear and increase cooperation. Scenarios illustrate how easily children compensate, how quickly they can crash, and why meticulous observation is essential in cases where verbal communication is limited.The book also highlights a part of EMS often ignored in training: documentation. Readers learn how to build a complete narrative, choose clear terminology, document interventions properly, and capture crucial environmental and historical details that affect patient care and legal protection. The emphasis is simple: good documentation saves jobs, protects medics, and strengthens continuity of care.Finally, What a Paramedic Should Know speaks to what happens after the tones stop. It addresses the emotional weight of the job, the mental strain of seeing others at their worst, and the importance of processing trauma instead of burying it. The book encourages mentorship, continuous skill development, and carrying forward the lessons learned so newer providers can stand on stronger ground.Whether you are a new EMT entering paramedic school, a seasoned medic looking to sharpen your edge, or an instructor searching for a resource that blends science with street wisdom, this book provides clear guidance grounded in real practice. What a Paramedic Should Know is more than a reference-it's a field companion, a confidence builder, and a reminder of why this work matters.
Diabetes
Diabetes: Its Cause and Its Treatment With Insulin by Russell M. Wilder is a landmark medical text that explores the origins, physiology, and management of diabetes at a pivotal moment in medical history-the early adoption of insulin therapy. Written by one of the pioneering physicians in the field, this work provides a clear, authoritative explanation of what diabetes is, how it affects the body, and why insulin revolutionized treatment and patient outcomes.Wilder carefully examines the metabolic disturbances underlying diabetes, the clinical signs and symptoms, and the scientific foundations of insulin as a therapeutic breakthrough. He provides detailed guidance on dosage, administration, diet management, and the monitoring of patient responses-making the book both a scientific milestone and a practical manual for early practitioners.Historically significant and medically insightful, this volume serves as an essential reference for students of medical history, endocrinology, diabetology, and public health. It offers a rare window into the evolution of diabetes care and the transformative impact of insulin on millions of lives.
The Power in My Pulse
In The Power in My Pulse, Imani Scott-Thompson takes readers on a raw and powerful journey through life with epilepsy, trauma, athletics and the pursuit of self-discovery. From childhood challenges to the weight of grief, from navigating countless epileptic obstacles to chasing dreams on and off the court, Imani reveals how resilience is about finding the courage to rise with it.This book is a testament to the unshakable power of the human spirit, a reminder that every struggle carries the possibility of transformation, and proof that purpose can be found even in life's hardest battles.Whether you live with epilepsy, have faced trauma, or are simply searching for inspiration, The Power in My Pulse will remind you that your story matters, your voice is powerful, and your pulse is proof that you are still here and capable of overcoming, capable of thriving.
Odd Girl Out, Doctor Within
Dr. Remina Panjwani is more than a distinguished Doctor of Internal Medicine, she is a visionary who redefines what it means to heal. Through her own personal and professional evolution, she embraces a more holistic, integrative approach-one that honors both science and soul, combining knowledge and compassion. Dr. Remina Panjwani is a highly regarded speaker, empowerment advocate, and the founder of Optimizing Wellness Together."Odd Girl Out, Dr. Within, a Story of Purpose, Pillars, and Personal Power," is a pillar-by-pillar testament to perseverance, purpose, and the power of self-belief. From the weight of generational and cultural expectations to the quiet ache of not belonging, Dr. Remina Panjwani's journey is one of remarkable transformation. Once told she wasn't enough-not smart enough, not strong enough, not the right "fit"-she rose from the shadows of doubt to become a dynamic, empowered physician and integrative healer whose light continues to inspire.In this deeply personal narrative, Dr. Remina Panjwani invites readers into her world where medicine meets mindfulness, science meets spirit, and healing is redefined as a journey of connection, not just correction. Her story is not only one of redemption, but of renewal. A living example that true strength lies in the heart that keeps choosing love, empathy, and hope, no matter the obstacles.A book for dreamers, healers, and anyone searching for meaning beyond survival- "Odd Girl Out, Doctor Within is an inspiring reminder that the human spirit, when nurtured with compassion, can rise above anything."Dr. Remina's story is the embodiment of resilience, grace, and purpose. A modern-day story of The Little Engine That Could." Greg Reid #1 Best-Selling Author, Founder of The Secret Knock"Dr. Remina's story is a tender-hearted testament to resilience, leaving the reader in tears of resonance and hope." Nita Patel, Artist, Author, Psychologist
Balance from Within
Balance From Within: Autoimmunity, Stress, and the Path to Resilience Living with autoimmunity often feels like fighting an invisible battle. Symptoms come and go, answers are delayed, and the body feels unpredictable. Balance From Within offers clarity and hope, explaining how autoimmunity develops, how stress fuels the cycle, and what practical steps can restore resilience.With a compassionate voice and whole-person perspective, this book explores the impact of genetics, trauma, emotions, reproductive health, and lifestyle on immune function. Readers will find tools to better understand their own patterns, support their nervous system, and create pathways toward greater stability.Autoimmunity doesn't have to mean constant confusion. With knowledge and support, balance is possible starting from within. Dedicated to Ineka Adams and all who continue to overcome immunity challenges.
How Metaphors Shape Biotechnology
This volume presents the proceedings of an interdisciplinary workshop at Technical University Braunschweig. Focusing on biotechnology, experts from biology, biotechnology, ethics, philosophy, theology, education, and social sciences investigated how metaphors shape scientific language. They examined conceptual, absolute, and hidden metaphors (e.g., "genetic scissors," "genetic code," "antibody," and "life") in molecular biology and biotechnology, exploring their roles in describing phenomena, guiding research, and influencing public perceptions. Through presentations, discussions, and collaborative writing, participants investigated how metaphors generate and transform knowledge, affect views of life and therapy, and inspire innovation. This volume synthesizes key findings, analyses, and writing conversations in both German and English, integrating systematic metaphor analysis with ethical, philosophical, and pedagogical perspectives on the significance of metaphors in biotechnology research and dissemination. Special attention was paid to metaphors' role in public communication, potentially determining acceptance or rejection of biotechnological advances. Ultimately, the workshop underscored how metaphors influence scientific progress in multiple ways and therefore require critical reflection.
Clinical Management of Audiological Disorders
Profound sensorineural hearing loss can be successfully treated with cochlear implants. In recent decades, great success has been achieved for these devices when used in quiet environments. However, cochlear implant users still face challenges in everyday communication. These include, for example, soft or distant speech, reverberation, interference of speech by sounds with different temporal characteristics, and varying numbers and locations of interfering signals.There are a variety of approaches to address this challenge, including digital signal processing algorithms, bilateral and bimodal provision, etc. Furthermore, research methods utilized to study this topic include, e.g., psycho-acoustics, speech audiometry, electrophysiology, virtual acoustics, data-logging, and questionnaires.
Indian Pharmacy Laws
"Indian Pharmacy Laws: Foundations and Applications" is a seminal work that provides a unified and structured approach to understanding the intricate web of laws and regulations governing the pharmaceutical industry in India. The authors have carefully crafted each chapter to provide not only theoretical knowledge but also practical applications, using case studies, real-world examples, and detailed explanations to make the guide comprehensive and useful. The book covers a wide range of topics, including laws related to the manufacture, licensing, import, export, and sale of medicines, as well as emerging trends, global harmonization efforts, and the impact of evolving technologies and regulations on the industry. By bringing together all relevant topics under one roof, this book aims to empower its readers with the knowledge needed to succeed in the dynamic and highly regulated field of pharmaceuticals in India.
New Strategies in Preventing Inflammatory and/or Oxidative Stress-Induced Damages in Ischemia-Reperfusion Injury, 2nd Edition
This Reprint compiles recent advances in the understanding and prevention of ischemia-reperfusion injury, a major challenge in modern medicine affecting organs such as the brain, heart, liver, kidney, and lung. This collection highlights the complex interplay between oxidative stress, inflammation, and metabolic imbalance, offering a comprehensive view of current experimental and translational strategies aimed at reducing tissue damage after reperfusion.The contributions in this Reprint explore novel antioxidant and anti-inflammatory approaches, ranging from natural compounds and molecular inhibitors to metabolic interventions and epigenetic modulation. Studies include the use of marine bioactive extracts, the modulation of redox-sensitive signaling pathways, extracellular vesicle-mediated protection, microRNA targeting, intermittent fasting, and complement inhibition.Together, these studies illustrate a paradigm shift from isolated antioxidant therapies toward integrated, multimodal strategies that combine redox control with immune and metabolic regulation. This Reprint provides valuable insights for researchers and clinicians seeking innovative approaches to mitigate ischemia-reperfusion injury across different organ systems and experimental models.
