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The 9-to-5 Body
Stiff shoulders, tight hips, and drained energy don't have to be the cost of a desk job. The truth is that the 9-to-5 doesn't just shape your schedule-it shapes your body, your posture, and even your stress levels. Yet the solution isn't squeezing in more gym time or buying expensive gadgets. The key is learning how to turn your workday itself into a powerful engine of mobility, strength, and focus. This book delivers practical, science-based strategies that show how to reverse the hidden toll of office life through simple, precise practices woven directly into the flow of your day. Whether you're dealing with aching joints, mid-afternoon crashes, or the creeping slump of poor posture, you'll discover how to reclaim energy and resilience without stepping away from your career. Inside, you'll find: - Desk workout routines that build strength and stability in minutes, not hours - Smart mobility exercises for desk jobs that restore hips and shoulders without disrupting workflow - Proven posture correction at desk strategies that align your body naturally, not through willpower alone - Ergonomic tips for home office setups that truly protect, rather than just look impressive - Tools for cortisol management at work to lower stress and sharpen focus throughout the day - Quick "movement snacks during workday" that keep stiffness from ever setting in Designed for busy professionals, remote workers, and anyone caught in the trap of constant sitting, this is not about chasing perfection or adding hours to your routine. It's about building a clear system-a workday fitness plan-that helps you stay strong, mobile, and energized while you work. By the end, you'll have the clarity and confidence to transform the way you move, feel, and perform-right from your desk.
New Updates in Oral and Maxillofacial Surgery
In recent years, with the rapid development of medical equipment, surgical techniques, and biomaterials, the field of oral and maxillofacial surgery has progressed to providing digital and personalized treatments. This includes digital imaging, digital impressions, jaw modeling, 3D planning of complex oral prosthetics, osteophytes and implant placement, and minimally invasive surgery, such as endoscopic and functional surgery. This Reprint, entitled "New Updates in Oral and Maxillofacial Surgery", aims to discuss personalized treatment and future trends in oral and maxillofacial surgery. A variety of topics are discussed, including the following: Orthognathic surgery and surgical treatment/correction of dental and maxillofacial malformations;Head and neck cosmetic surgery;Oral cancer;Reconstructive surgery;Management of oral diseases;New methods and techniques in oral and maxillofacial surgery;Oral and maxillofacial soft and hard tissue trauma and reconstruction techniques;Drug-related osteonecrosis of the jaw;New diagnostic and therapeutic tools for the management of potentially malignant diseases of the oral cavity.
Worship in a Time of Pandemic
This Special Issue Reprint addresses the challenges and possibilities that Christian liturgies faced during the recent global pandemic. These challenges and possibilities are discussed from theological, historical, and practical perspectives. The authors of the nine studies range across a variety of Christian denominations and areas, from the U.S. to Venezuela to Korea, and address a variety of issues, from liturgical time to worship music to spiritual communion.
What We See through Cardiac Imaging
This Reprint showcases the transformative role of multimodality cardiac imaging in contemporary cardiovascular care. It brings together studies demonstrating how structural, functional, and dynamic insights from echocardiography, cardiac magnetic resonance, computed tomography, and other techniques are now central to diagnosing disease, stratifying risk, and guiding therapy across congenital, structural, coronary, and heart failure conditions. Taken together, these contributions illustrate that cardiac imaging has moved beyond simple anatomical descriptions to become a predictive, therapeutic shaping tool and highlight the need for standardized protocols and multicentre validation
Ethics, Social Responsibility and Quality of Life in Times of Crisis
Crises in organizations can have either devastating consequences or provide the opportunity or improving people, communities, and organizations. However, more often than not, a crisis, either internal or external to the organization, can expose breaches in the overall quality of life and have a dramatic impact on issues such as the psychological safety of individuals and the overall health and well-being of communities and organizations. As a result, stakeholders will react, experience, and be impacted in different ways based on how the organization and its leadership consider issues such as overall quality of life, well-being, and psychological safety. The research papers in this special collection examine the complex issues of ethics, social responsibility, and the importance of well-being for individuals and organizations-particularly during times of crisis.
Cutting-Edge Research on Physical Fitness Profile in Soccer Players
At the professional level, football is a sport where players run approximately 11 kilometers per game, and about 10% of this constitutes high-intensity running. Additionally, they engage in various other intense actions during the game, which often determine its outcome. In recent years, the pace of the game and the number of matches have significantly increased. To cope with this, footballers need to possess highly developed physical abilities. The introduction of new technologies (e.g., GPS) in training assists coaches in better managing the demands of microcycle design. Moreover, at developmental ages, a special emphasis should be placed on the development of physical abilities, and coaches should exploit the "windows" that appear at each age to maximize performance.This Special Issue offers the opportunity to publish high-quality original papers, systematic reviews, and meta-analyses focused on the development of soccer fitness in both young athletes and adults. More specifically, in this Special Issue, we aim to highlight recent research concerning the physical fitness profile of both young and adult football players, as well as studies focusing on new training methods and the use of new technologies in the coaching process.
Public Health Consequences of Social Isolation and Loneliness
Loneliness carries a significant social stigma, as a lack of friendship and social ties are socially undesirable, and social perceptions of lonely people are generally unfavorable. Lonely people often have very negative self-perceptions, believing that the inability to establish social ties is due to personal inadequacies or socially undesirable attributes. The effect of loneliness on public health is obvious and validated by numerous studies. The negative effects of loneliness may include physical illness, emotional issues, and even mortality, which underline its serious effects. This collection includes chapters on loneliness as a public health issue; introduces a newly developed scale to measure loneliness in intimate relations; investigates the connection between loneliness and physical ailments; studies how COVID-19 affected the experience of loneliness; and presents approaches to reduce and manage loneliness.
Family Nurse Practitioner Certification Prep
Kaplan's Family Nurse Practitioner Certification Prep is your step-by-step guide to success on the FNP exam, with review and practice for FNP exams from both credentialing organizations--the American Academy of Nurse Practitioners (AANP) and the American Nurses Credentialing Center (ANCC). This Second Edition is thoroughly reworked and updated to focus on how to apply clinical skills, using a problem-solving approach to diagnosis and management. Here's what makes our guide stand apart: Focus on chief concerns. The book is organized around chief concerns rather than traditional body-system formats, offering a more intuitive, real-world approach to generating the differential diagnosis. Common chief concerns are then broken down by body system. Case-based approach. Each chapter features a patient scenario, with guided discussion to strengthen your clinical reasoning and understanding. Learn by example. Follow along as an experienced clinician applies a problem-solving approach to the diagnosis and management of the patient's chief concern. Concise outline format. Short paragraphs and bullet points put the information that's most crucial for exam success front and center. Created and reviewed by experienced mid-level clinicians and educators, this versatile resource is suitable for all clinicians, especially those at the entry level seeking clarity and confidence in generating the differential diagnosis. Proven Strategies. Realistic Practice. 46 succinct chapters investigating chief concerns commonly seen in family practice 13 diagnostic areas organizing the chief concerns: Integumentary, HEENT, Cardiovascular, Respiratory, Gastrointestinal, Genitourinary, Female health, Musculoskeletal, Neurological, Endocrine, Hematologic, Psychiatric, and Health promotion & population-based care Practice questions in each chapter, with detailed rationales for correct and incorrect answer options Sick and well visit approaches for encounters with patients ranging in age from newborn to geriatric Guided examples of clinical decision-making at each step in patient management Callout boxes identifying associated conditions, distinguishing similar presentations, and more Parallel presentation of topics across the book for easy navigation Index by body system or chief concern, and index by diagnosis Expert Guidance. Exclusive test-taking strategies, study tips, and clinical reasoning that optimize your preparation--including Kaplan's Nurse Practitioner Decision Tree The official course book used in Kaplan's highly regarded FNP Review Course We know the test--Kaplan's experts ensure our practice questions and study materials are true to the exam We invented test prep--Kaplan (www.kaptest.com) has been helping students for 80 years, and our proven strategies have helped legions of students achieve their dreams
Nursing as Caring
Nursing as Caring: A Model for Transforming Practice presents a profound and transformative approach to nursing, emphasizing care as the fundamental core of the profession. Developed by Anne Boykin and Savina O'Bryan Schoenhofer, this influential model redefines nursing as a discipline rooted in human connection, respect, and shared values, shifting the focus from tasks and procedures to authentic caring relationships.The authors describe caring as an innate human quality and position nursing as the professional expression of that caring in practical, meaningful ways. Through philosophical grounding, theoretical explanation, and real-world applications, the book demonstrates how nurses can create healing environments, honor personhood, and cultivate deeper patient-nurse partnerships.This essential work is widely embraced in nursing education and practice for its clarity, depth, and human-centered perspective. Ideal for nursing students, educators, practitioners, and leaders seeking a more compassionate, holistic, and person-focused model of care, Nursing as Caring offers an inspiring vision for the future of the nursing profession.
The Time of My Life
You Can Live A Life Of Fulfillment!Three to five years to live was Marc McCoy's prognosis after a revelation from God and a terminal cancer diagnosis. Once he came to terms with his remaining "shortened lifespan," a beautiful world began to unfold. It is a world of love, peace, purpose and unspeakable joy.The Time Of My Life is the story of McCoy's journey from a life of promising tomorrows to a life of joyful moments today. God took away his focus on tomorrow but, left him with a much better today and a mission to show others the joy that awaits those who embrace one of Jesus' fundamental teachings. "Tomorrow will bring its own worries," Jesus said in Matthew 6:34. Why is it essential that we live for today and shed our worries about tomorrow? Even if we could, what is the point?"So teach us to number our days that we may get a heart of wisdom," Moses asked in Psalms 90. Why are our lives so short? What exactly is the wisdom gained from knowing the number of our days? The Time Of My Life provides answers to those and many other of life's tough questions.None of us are guaranteed tomorrow. This book shows how to apply the wisdom of letting go of tomorrow to your busy lives today and experience the life you were meant to live. Learn to see the joy in a life lived moment to moment Experience the relief in letting go of tomorrow's burdens Discover the wisdom of knowing the short number of your days Marc McCoy, a cancer survivor, was forced to address life's most difficult questions and overcome some of life's biggest challenges. Retired from a 45-year career in radio broadcasting, media, and marketing; from talk show host to consultant, to general manager, he has worked with some of America's most respected radio, television and newspaper companies. McCoy and his wife, Cindy are active members of The Woodlands United Methodist Church, in The Woodlands, Texas. He and Cindy have two adult children and four grandchildren.
Shit Happens
Behind the provocative title is a vital message. The last frontier to explore is the world within our own bodies, where great armies of billions of microbes make war to determine whether we, their hosts, shall live happy, healthy lives or degenerate, decay and die. Professor Tom Borody has been studying and researching the human microbiome for a lifetime. It is a microcosm of our world, which we have damaged through ignorance or carelessness of the consequences. We have laid waste to the living universe inside us with antibiotics. They have upset the balance of our microbiome and laid us open to a whole host of 'incurable' illnesses, not just gastric conditions but Multiple Sclerosis, Parkinson's, Alzheimer's, Crohn's Disease and many more. There is hope. If we are smart and swift, we can repair the damage. In 1988, Professor Borody performed the first Faecal Microbial Transplants (FMT) in Australia. He gave his patient back her life and livelihood. Hundreds of thousands more FMTs have taken place since then, worldwide. Right now, there is a desperate need for more research and more large-scale clinical trials. Big Pharma won't support it because it won't generate more pills and potions for them to sell. It turns out the most effective remedy for our many ailments was deep inside us all the time. This book will change forever the way you think about your own body. No shit.
The Complete Long COVID Handbook
The Complete Long COVID Handbook: Endothelial Dysfunction & MicroclotsVolume 6 of the Series by Robert Groysman, MDWhy does Long COVID make you feel so exhausted, foggy, short of breath-or worse-even when your tests look normal?One of the most overlooked causes may be hiding in your blood.New research reveals that many Long COVID symptoms may be driven by endothelial dysfunction (damage to blood vessel linings) and microclots (tiny, persistent clots that block oxygen flow). These invisible issues can affect your brain, muscles, nerves, and organs-leaving you sick, frustrated, and without answers.In this groundbreaking and easy-to-understand guide, physician Dr. Robert Groysman walks you through: What endothelial dysfunction and microclots are-and how they may be driving your symptomsWhich tests can uncover these problems (even when basic labs look fine)What symptoms suggest your circulation is impairedNatural and medical treatment options, from supplements to apheresisWhat to expect with recovery, and how to track your progressThis book is written for patients, families, and healthcare providers who want real explanations, practical tools, and a hopeful path forward. Whether you're newly diagnosed, stuck in a cycle of confusing symptoms, or searching for better care-this book helps you connect the dots and reclaim control.You're not imagining it. You're not alone. And you're not without options.
Cellular and Molecular Mechanisms in Immune Regulation
This is a Reprint of the first edition of the Special Issue on "Cellular and Molecular Mechanisms in Immune Regulation" published by the journal Cells in 2024-2025. The reprint starts with a review of the latest advances in molecular mechanisms of immunity and the effect of X chromosome loss in immune function. Next, we focus on autoimmunity by exploring the use of circular RNAs as biomarkers in multiple sclerosis and the role of circulating T cell subsets in Type 1 diabetes. We conclude reviewing the part played by lipid biosynthesis metabolism in the inflammatory response mediated by microglia in neurodegeneration and wound healing in the central nervous system. The importance of Immune regulation for preventive medicine is highlighted by a review on the interactions of T follicular helper cells and B cells and their role in the control of viral infections and vaccine design. Next, we explore how immune cell populations affect the prognosis of cancer patients treated by Immunotherapy using immune check point inhibitors. We conclude this part with an emphasis on tissue resident memory T cells (TRMs) and their potential in the control of cancer metastasis. The Special Issue concludes with articles highlighting the interactions between the environment and the immune system, specifically on the generation of tolerogenic dendritic cells mediated by oxygen tension in tissues and exposure to ultraviolet light (UV) on the skin. Thus, this reprint provides a glimpse of the multi-cellular immunoregulatory networks implicated in autoimmune diseases, infection and cancer as well as during normal interactions with the environment.
Inflammatory Bowel Disease (IBD)
Inflammatory bowel diseases (IBDs) are characterized by chronic inflammation of the GIT, with two main clinical manifestations: Crohn's disease, whose pathogenesis involves any part of the gastrointestinal tract, and ulcerative colitis, in which inflammation is limited to the colon. This gastrointestinal tract inflammation leads to symptoms such as bleeding, abdominal pain, diarrhea, malnutrition, and increased intestinal permeability. Among the factors involved in the pathogenesis of these diseases, genetics, dysregulation in the intestinal microbiota, and environmental factors such as diet and physical inactivity stand out. Considering the severity of symptoms related to IBDs, alternative therapies have been sought to alleviate intestinal discomfort, and physical exercise, dietary interventions, and nutritional supplements can bring benefits, which include improving the composition of the microbiota, intestinal tract, and its antioxidant and anti-inflammatory action, which may implement a protective action on the permeability in the gastrointestinal tract. This Issue Reprint summarizes various papers published in the collection "Inflammatory Bowel Disease (IBD): Clinical Diagnosis and Treatment", which aims to provide an approach to the clinical diagnosis and treatment of IBDs. This Reprint includes papers dedicated to the clinical diagnosis of IBDs, physical exercise and nutrition in IBDs, microbiota and IBDs, and body composition in IBDs.
Disease Control Priorities, Fourth Edition (Volume 2)
The fourth edition of Disease Control Priorities (DCP) builds on the three previous editions published from 1993 through 2018. DCP4 uses a collaborative, country-led approach to summarize, produce, and help translate economic evidence to inform better priority setting and capacity strengthening for universal health coverage, public health functions, pandemic preparedness and response, and intersectoral and international action for health. New modeling for DCP4 suggests more than a 20 percent probability in the next decade of another pandemic with mortality comparable to COVID-19. Volume 2, Investing in Pandemic Prevention, Preparedness, and Response, provides practical guidance for countries to prevent, prepare for, and respond to pandemics. Drawing on COVID-19 lessons, it identifies key priorities to build resilient systems that protect lives and economies through evidence-based national and regional actions. Early chapters focus on prevention-- reducing zoonotic risks, strengthening biosafety measures, improving early detection systems, and rapidly characterizing and containing outbreaks. Other chapters discuss targeted public health measures and broader public health and social measures to curb transmission. Core health system investments receive particular attention, especially oxygen systems, emergency care, and vaccine delivery infrastructure that serve both routine and pandemic needs. Later chapters address medical countermeasures, proposing prearranged financing and decentralized manufacturing to accelerate deployment and reduce disparities. Finally, the volume presents a comprehensive framework for pandemic financing that spans the entire pandemic cycle, emphasizing the need for timely, adequate, and effective financial resources. The framework is designed to support policy makers in countries at all income levels and provides a guide to appropriate financing tools for each stage of a pandemic
100+ Funny Short Stories for Seniors
���� A Joyful Gift They'll Actually Use (and Love)Tired of gift books that get put on a shelf and forgotten?This one gets opened, and enjoyed, again and again.This delightful collection of 100+ short, funny, and uplifting stories is specially written for seniors who appreciate lighthearted moments, simple pleasures, and a good laugh at any age.With large print, easy-to-read text, and clean humor, it's the perfect feel-good companion for quiet afternoons, family visits, or bedtime smiles.✨ What You'll Find Inside: - ✅ 100+ Short Feel-Good Stories - Light, easy reads that leave you smiling in just 5-7 minutes- ✅ Large Print for Easy Reading - Designed for comfort, with clear layout and reader-friendly language- ✅ No Drama, Just Delight - Safe, clean stories with heart and humor-never heavy or confusing- ✅ Perfectly Paced - Start and finish a story in one sitting, or read several at once- ✅ Varied and Engaging - Different characters, situations, and tones to keep things fresh and fun���� Perfect Gift Idea For: - Grandparents, parents, and elderly loved ones- Seniors in assisted living or recovering from illness- Caregivers looking for comforting and joyful materials- Readers who enjoy simple, heartwarming entertainment- Anyone who could use a smile-without scrolling a screen
The Effect of the Urinary pH in Urinary Tract Infections in Kidney Transplant Recipients
The focus of this book is to determine the impact of antimicrobial therapy in the outcome of asymptomatic bacteriuria in a cohort of kidney transplant recipients (KTR). To compare the outcome of lower urinary tract infection (UTI) caused by Escherichia coli in KTR treated with ciprofloxacin and fosfomycin, according to the urinary pH. To analyse the clinical and microbiological outcomes in lower UTI caused by different uropathogens in KTR treated with ciprofloxacin and fosfomycin, according to the urine pH. To study the prevalence, phenotypic characteristics, clinical impact, and outcomes of E. coli strains with LLQR and/or LLFR (low-level quinolone and/or fosfomycin resistant), treated with ciprofloxacin and fosfomycin, according to the urinary pH.
Unlocking Diagnosis Through Story and Touch
Basics of Physical Diagnosis: History Taking and Physical Examination is an essential guide for health science and medical students and senior practitioners to sharpen their history and diagnostic skills. It emphasizes the importance of observation, communication, and critical thinking in forming accurate diagnoses and building strong patient relationships. The book covers basic history-taking techniques using both systemic (medical) and functional approaches. It also includes assessment techniques for each body system, outlining the appropriate steps and highlighting the key anatomical landmarks relevant to each system.
Green Nanoscience for Health and Healing
This book explores the green synthesis and structural characterization of selenium nanoparticles using Moringa peregrina leaf extract, revealing their potent anticancer, antioxidant, and antibacterial properties. Dr. Samer Y. Al-Qaraleh presents a compelling fusion of nanotechnology and plant-based science, supported by advanced analytical techniques (UV-Vis, FTIR, XRD, SEM, TEM). Bridging sustainable innovation and biomedical potential, this work offers fresh insight into eco-friendly approaches to modern therapeutic challenges.
Quality of Life After Surgically Treated Ankle Fractures
The general objective of this thesis was to evaluate and compare the functionality, pain and quality of life (QOL) of active and inactive adult individuals whose ankle fracture (AF) was surgically treated; and the specific objectives were: i) To conduct a systematic review evaluating functional outcomes and the QOL of patients with surgically treated AF compared with the nonfractured population; ii) To compare adult men and women residing in Brazil's interior who were treated with open reduction and internal fixation (ORIF) following AF; and iii) To describe and prospectively analyze unstable AF, surgically treated through ORIF, in adults in the Jequitinhonha Valley region of Brazil. Questionnaires such as the IPAQ, MMSE, SF-36, VAS, and sociodemographic and clinical questionnaires were administered. The morphology of the AFs was analyzed according to the AO Foundation and Orthopaedic Trauma Association (AO/OTA) classification system. Of the 86 patients, young men predominated in all variables studied. The most common cause of injury was motorcycle accidents, followed by soccer accidents (p
Converging Frontlines
In an era where clinical care is rapidly evolving, Converging Frontlines: Multidisciplinary Approaches to the Future of Clinical Medicine offers a timely exploration into the collaborative forces reshaping patient outcomes. From operating rooms to outpatient clinics, medicine is no longer practiced in silos. This book brings together a powerful collection of essays that examine how interdisciplinary teamwork, technological innovation, and patient-centered strategies are transforming modern care delivery. Author Mohamed Salem, a nationally recognized researcher and future physician, delves into pressing issues such as perioperative optimization, subclinical atherosclerosis, climate-driven health crises, and the integration of AI in clinical decision-making. Each chapter presents a well-researched, accessible analysis grounded in current evidence while offering bold visions for the future. Topics range from stroke care pathways and anticoagulation strategies to the ethical imperatives of health equity and regenerative medicine. Whether you're a medical student, resident, or practicing clinician, this book serves as a vital roadmap to navigate the increasingly complex healthcare landscape. It emphasizes the power of merging clinical perspectives-across specialties, roles, and systems-to improve outcomes, reduce risk, and ensure equitable access in the age of medical advancement. Converging Frontlines is more than a medical analysis; it's a call to action for a future where collaborative care is the standard-and where every patient benefits from the strength of an integrated clinical vision.
Effect of Zingiber Officinale Extract on Some Pharmacological Parameters in Rodentse
Ginger is a perennial plant that grows in India, China, Mexico and several other countries. The rhizome is used as both spice and in herbal medicine. Many studies have been done on pharmacological effect of ginger extract and our paper has been focused on cytoprotective effect of ginger on ethanol induced gastric injury in mice. Many drugs have been used in the treatment of peptic ulcer but each of them associated with different side effect so trends today toward use of herbal medicine which was associated with adverse effect. Ginger hydroalcoholic extract contain different consistent with anti-ulcer properties like 6-Gingersulfonic acid and three monoacyldigalactosyl glycerol including ginger glycolipid A. B. C .The mechanism of ginger extract may be due to counteracting the active oxidant radicals, decreasing mucosal cell shedding and thicking the mucus membrane so ginger extract has antiulcer properties when used in accurate dose and accurate duration. Keywords: Cytoprotective effect; Ethanol; Ginger hydroalcoholic extract; Mice; Zingiber Officinal
Data Driven Insights in Healthcare
This Reprint presents a collection of data-driven investigations that advance healthcare research beyond traditional theory-driven approaches. The articles featured in this collection demonstrate how observational experiences and big data analytics can uncover novel insights that improve healthcare practice and delivery.This Reprint showcases diverse methodologies for extracting value from healthcare data sets, including qualitative analysis of comments, data mining of large data sets, exploratory data techniques utilizing artificial intelligence and machine learning, and other innovative approaches to discovering patterns and relationships within complex healthcare data. Review articles examining the application and potential of data-driven approaches in healthcare are also included.The research compiled in this Reprint illustrates how data exploration generates new possibilities and enhances understanding of current theories and practices in healthcare. The studies employ various data analytic methods to reveal relationships among variables and provide actionable insights for healthcare researchers and practitioners. Collectively, these works demonstrate that discoveries emerging from systematic data exploration merit continued investigation and offer practical value for advancing healthcare delivery and outcomes.
Thyroid Disease
This Reprint presents novel developments in thyroid disease diagnosis and treatment, addressing both common and rare thyroid conditions. The collection emphasizes the evolution from traditional imaging-based assessments toward personalized, multi-parameter approaches that integrate patient demographics, molecular markers, and advanced technologies. Key contributions explore enhanced risk stratification methods for thyroid nodules, incorporating age, gender, and clinical variables alongside sonographic features to improve diagnostic precision. This Reprint examines shifting epidemiological patterns in thyroid cancer, revealing demographic changes and evolving disease presentations over the past two decades.Treatment innovations highlight refined radioiodine approaches for managing both benign goiter and differentiated thyroid cancer. Novel redifferentiation strategies targeting molecular pathways offer promising alternatives for patients with radioiodine-refractory disease. New developments in thyroid cancer biomarkers have resolved several longstanding analytical problems, with improved assays offering greater reliability and enhanced monitoring options. The Reprint also addresses specialized topics, encompassing pregnancy considerations in autoimmune thyroid disorders and surgical management strategies for uncommon conditions such as thyroid hormone resistance.
New Insights into Suicide and Mental Health Conditions
The Reprint entitled "New Insights into Suicide and Mental Health Conditions" gathers cutting-edge research focused on the underlying neurobiology, clinical interventions, and methodological innovations addressing suicide and suicidal behavior in the context of mental health disorders. Suicide remains among the most urgent public-health challenges worldwide, and many individuals who die by suicide have longstanding psychiatric disorders, and yet face limited access to effective interventions. This Reprint highlights contributions that advance our understanding of etiological mechanisms, identify novel therapeutic approaches-including brain-based and neurophysiological interventions-and develop rigorous trial designs for use in high-risk populations. The scope spans pharmacological and non-pharmacological interventions, brain stimulation techniques, digital and biomarker-driven risk prediction, psychometric instrument validation for suicidality screening across diverse settings, and contextual factors shaping implementation of evidence-supported strategies. With an emphasis on bridging translational neuroscience and clinical practice, this compilation aims to accelerate progress in preventing suicidal ideation and behavior and to improve outcomes for individuals affected by severe mental health conditions.
Recent Advances in Understanding Systemic Sclerosis
Systemic sclerosis (SSc) is a complex, multifaceted autoimmune disease characterized by vascular abnormalities, immune system dysregulation, and progressive fibrosis of the skin and internal organs. Despite significant strides in understanding the pathogenesis of SSc, it remains a challenging condition to diagnose and manage due to its heterogeneity and its variability in clinical manifestations.We are pleased to provide a comprehensive overview of the current state of knowledge, treatment, and future perspectives of therapeutic approaches in this Special Issue.
Mitochondria
This Reprint brings together a curated selection of original research and review articles that explore the multifaceted roles of mitochondria in health and disease. It highlights mitochondria as dynamic organelles that extend far beyond energy production, acting as key regulators of cellular signaling, metabolic homeostasis, and stress responses. The collection spans a broad biomedical spectrum, from mitochondrial quality control in fertility and early-life programming to their dysfunction in chronic diseases such as cardiovascular disorders, liver pathologies, and neurodegenerative conditions. Special attention is given to sex-specific responses, developmental origins of mitochondrial health, and emerging therapeutic strategies targeting mitochondrial pathways. This Reprint provides a comprehensive and timely synthesis for researchers and clinicians who are interested in mitochondrial biology and its translational potential.
Autism Causes Unveiled
The Book Destined to End the Autism Epidemic is Finally Here.For over a century, autism has remained a profound medical mystery, its causes debated and misunderstood. In Autism Causes Unveiled, author Dinesh Danny cracks this century-old enigma, exposing the hidden truth behind the autism epidemic and offering a groundbreaking perspective never explained before.The evidence is all around us, yet it has been meticulously concealed by a carefully managed narrative. And no, it's not what you think. It's not primarily vaccines. The real culprit is a traumatic brain injury at birth-a catastrophic event hidden by the birth process itself and deliberately buried by those with the most to lose from birth injury litigation. The proof is hiding in plain sight, embedded within the warnings on the label of the only FDA-approved labor induction drug: Pitocin. The exact way this tragedy unfolds in maternity wards is laid bare through the author's deeply personal story with his two sons, both impacted by this birth injury.This book is a deep dive into the shocking truth: The True Cause: Discover the actual mechanism of injury from labor drugs and the hospital protocols that are being ignored.A Flawed Theory Exposed: Uncover why the genetic origin theory based on identical twins is fundamentally flawed and why this skyrocketing neurodiversity is a direct result of systemic obstetric malpractice at birth.The Damaged Brain: Learn how fundamental neuronal tracts are being damaged and severed, leading to the disconnected brain that defines autism.The Vaccine Connection: Understand the complex interplay of vaccines with a pre-existing brain injury, and how they can make brain damage more permanent by stopping recovery"Autism Causes Unveiled" is essential reading for anyone touched by autism- parents, well wishers, caregivers, physicians of all specialities, birth injury lawyers, politicians, and health officials. It's for everyone with an interest in learning more about the biggest medical crisis in the history of the world.
Methylene Blue
Methylene Blue (MB) is a blue dye first developed by a German scientist, Heinrich Cato in 1876. Originally used as a textile dye but later found to have medicinal properties. This book discusses the use of MB in clinical medicine. The book also looks at the historical uses of methylene blue, such as in the treatment of malaria.As a dye, it can be used in surgery to highlight structures, such as fistulae. In pathology, it can be used as a tissue stain. In emergency medicine it can be used to treat methaemoglobinaemia, carbon monoxide poisoning as well as vasoplegic shock. In clinical medicine, MB can be used in a variety of conditions as it has anti-inflammatory, antiviral, antibacterial and anticancer properties. MB enhances the activity of the mitochondria and can be used to increase energy. MB can cross the Blood Brain Barrier and has been found to reduce neuroinflammation and can be used in neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and a host of other degenerative diseases. Although much of the research has been done in animal models, due to the safety, it can be translated to human use.One great myth is that methylene blue is dangerous. To some extent this is true, however, this can also apply to any drug, vitamin, mineral and herb. Dosage is the key issue. Another key issue is that it is contra-indicated in certain people. Therefore, it is up to the prescribing doctor to determine the correct dose in people who can use it safely Hopefully this book will encourage everyone to look more closely at MB and use it to treat conditions that up till now have no specific treatment.
The Power in My Pulse
In The Power in My Pulse, Imani Scott-Thompson takes readers on a raw and powerful journey through life with epilepsy, trauma, athletics and the pursuit of self-discovery. From childhood challenges to the weight of grief, from navigating countless epileptic obstacles to chasing dreams on and off the court, Imani reveals how resilience is about finding the courage to rise with it.This book is a testament to the unshakable power of the human spirit, a reminder that every struggle carries the possibility of transformation, and proof that purpose can be found even in life's hardest battles.Whether you live with epilepsy, have faced trauma, or are simply searching for inspiration, The Power in My Pulse will remind you that your story matters, your voice is powerful, and your pulse is proof that you are still here and capable of overcoming, capable of thriving.
Diabetes
Diabetes: Its Cause and Its Treatment With Insulin by Russell M. Wilder is a landmark medical text that explores the origins, physiology, and management of diabetes at a pivotal moment in medical history-the early adoption of insulin therapy. Written by one of the pioneering physicians in the field, this work provides a clear, authoritative explanation of what diabetes is, how it affects the body, and why insulin revolutionized treatment and patient outcomes.Wilder carefully examines the metabolic disturbances underlying diabetes, the clinical signs and symptoms, and the scientific foundations of insulin as a therapeutic breakthrough. He provides detailed guidance on dosage, administration, diet management, and the monitoring of patient responses-making the book both a scientific milestone and a practical manual for early practitioners.Historically significant and medically insightful, this volume serves as an essential reference for students of medical history, endocrinology, diabetology, and public health. It offers a rare window into the evolution of diabetes care and the transformative impact of insulin on millions of lives.
What Paramedics Should Know
What a Paramedic Should Know is a practical, experience-driven guide built for the realities of modern EMS. This book strips paramedicine down to what truly matters: sharp assessment, calm decision-making, mastery of equipment, and the ability to stay steady when everything around you is falling apart. It blends clinical science, field-tested judgment, and real-world scenarios into a clear and direct roadmap for the working medic.The book starts with foundational skills, including detailed explanations of airway control, respiratory assessment, and circulation management. Readers learn how to identify subtle clinical clues, recognize early signs of decompensation, and intervene before a patient's condition turns critical. Trauma care is presented with equal clarity, using ATLS principles to walk the reader through mechanism of injury, primary and secondary assessments, hidden injury patterns, treatment priorities, and the teamwork required during chaotic scenes. Every section emphasizes how to think, not just what to do.Advanced Life Support is given the depth it deserves. The text explores cardiac monitor interpretation, the physics and physiology of defibrillation, troubleshooting equipment failures, and rhythm recognition under pressure. Real call examples highlight how a single misread waveform can change the entire outcome. Airway management receives the same level of precision, with honest discussions about intubation challenges, cricothyrotomy considerations, and the importance of knowing your tools as well as your anatomy.Pediatric care is addressed with realism and compassion. Each age group is explained through developmental needs, physiological differences, and communication strategies that help reduce fear and increase cooperation. Scenarios illustrate how easily children compensate, how quickly they can crash, and why meticulous observation is essential in cases where verbal communication is limited.The book also highlights a part of EMS often ignored in training: documentation. Readers learn how to build a complete narrative, choose clear terminology, document interventions properly, and capture crucial environmental and historical details that affect patient care and legal protection. The emphasis is simple: good documentation saves jobs, protects medics, and strengthens continuity of care.Finally, What a Paramedic Should Know speaks to what happens after the tones stop. It addresses the emotional weight of the job, the mental strain of seeing others at their worst, and the importance of processing trauma instead of burying it. The book encourages mentorship, continuous skill development, and carrying forward the lessons learned so newer providers can stand on stronger ground.Whether you are a new EMT entering paramedic school, a seasoned medic looking to sharpen your edge, or an instructor searching for a resource that blends science with street wisdom, this book provides clear guidance grounded in real practice. What a Paramedic Should Know is more than a reference-it's a field companion, a confidence builder, and a reminder of why this work matters.
Odd Girl Out, Doctor Within
Dr. Remina Panjwani is more than a distinguished Doctor of Internal Medicine, she is a visionary who redefines what it means to heal. Through her own personal and professional evolution, she embraces a more holistic, integrative approach-one that honors both science and soul, combining knowledge and compassion. Dr. Remina Panjwani is a highly regarded speaker, empowerment advocate, and the founder of Optimizing Wellness Together."Odd Girl Out, Dr. Within, a Story of Purpose, Pillars, and Personal Power," is a pillar-by-pillar testament to perseverance, purpose, and the power of self-belief. From the weight of generational and cultural expectations to the quiet ache of not belonging, Dr. Remina Panjwani's journey is one of remarkable transformation. Once told she wasn't enough-not smart enough, not strong enough, not the right "fit"-she rose from the shadows of doubt to become a dynamic, empowered physician and integrative healer whose light continues to inspire.In this deeply personal narrative, Dr. Remina Panjwani invites readers into her world where medicine meets mindfulness, science meets spirit, and healing is redefined as a journey of connection, not just correction. Her story is not only one of redemption, but of renewal. A living example that true strength lies in the heart that keeps choosing love, empathy, and hope, no matter the obstacles.A book for dreamers, healers, and anyone searching for meaning beyond survival- "Odd Girl Out, Doctor Within is an inspiring reminder that the human spirit, when nurtured with compassion, can rise above anything."Dr. Remina's story is the embodiment of resilience, grace, and purpose. A modern-day story of The Little Engine That Could." Greg Reid #1 Best-Selling Author, Founder of The Secret Knock"Dr. Remina's story is a tender-hearted testament to resilience, leaving the reader in tears of resonance and hope." Nita Patel, Artist, Author, Psychologist
Balance from Within
Balance From Within: Autoimmunity, Stress, and the Path to Resilience Living with autoimmunity often feels like fighting an invisible battle. Symptoms come and go, answers are delayed, and the body feels unpredictable. Balance From Within offers clarity and hope, explaining how autoimmunity develops, how stress fuels the cycle, and what practical steps can restore resilience.With a compassionate voice and whole-person perspective, this book explores the impact of genetics, trauma, emotions, reproductive health, and lifestyle on immune function. Readers will find tools to better understand their own patterns, support their nervous system, and create pathways toward greater stability.Autoimmunity doesn't have to mean constant confusion. With knowledge and support, balance is possible starting from within. Dedicated to Ineka Adams and all who continue to overcome immunity challenges.
You Cancer Vive
WARNING: CONTAINS EXPLICIT LANGUAGE - NOT FOR CHILDREN. Let's be honest: cancer is a jerk!You Cancervive is the cheeky, irreverent pep talk that reminds you you're stronger, louder, and far more stubborn than cancer ever expected.This book blends dark humor with real comfort - because sometimes laughter is the only thing stronger than fear.
How Metaphors Shape Biotechnology
This volume presents the proceedings of an interdisciplinary workshop at Braunschweig University of Technology in a collection of English and German articles (English summaries are provided for all German articles). Focusing on biotechnology, experts from biology, biotechnology, ethics, philosophy, theology, education, and social sciences investigated how metaphors shape the language of life science. The authors examined conceptual, absolute, and hidden metaphors (e.g., "genetic scissors," "genetic code," "antibodies," and "life") in molecular biology and biotechnology. By exploring their roles in describing phenomena, guiding research, and influencing public perceptions, the authors investigate how metaphors generate and transform knowledge, affect views of life and therapy, and inspire innovation. This volume integrates systematic metaphor analysis with ethical, philosophical, and pedagogical perspectives on the significance of metaphors in biotechnology research and dissemination. Special attention was paid to metaphors' role in public communication, potentially determining acceptance or rejection of biotechnological advances. Ultimately, the workshop underscored how metaphors influence scientific progress in multiple ways and therefore require critical reflection.
Documentation and Pharmaceutical Regulatory Writing for Students and Practitioners
"Documentation and Pharmaceutical Regulatory Writing for Students and Practitioners" is an exhaustive resource that aims to bridge the gap between academic curricula and industry requirements in the pharmaceutical domain. The book is carefully crafted to serve as a comprehensive guide for students, academicians, and professionals seeking to master the intricacies of regulatory writing and documentation practices. It provides a thorough understanding of the key aspects of documentation, including regulatory dossiers, SOPs, validation protocols, and clinical trial documentation, as well as international regulatory guidelines from the FDA, EMA, and ICH. The book also places special emphasis on practical aspects, incorporating real-world examples, case studies, and checklists to provide a hands-on learning experience and facilitate application in professional scenarios.
Clinical Management of Audiological Disorders
Profound sensorineural hearing loss can be successfully treated with cochlear implants. In recent decades, great success has been achieved for these devices when used in quiet environments. However, cochlear implant users still face challenges in everyday communication. These include, for example, soft or distant speech, reverberation, interference of speech by sounds with different temporal characteristics, and varying numbers and locations of interfering signals.There are a variety of approaches to address this challenge, including digital signal processing algorithms, bilateral and bimodal provision, etc. Furthermore, research methods utilized to study this topic include, e.g., psycho-acoustics, speech audiometry, electrophysiology, virtual acoustics, data-logging, and questionnaires.
New Strategies in Preventing Inflammatory and/or Oxidative Stress-Induced Damages in Ischemia-Reperfusion Injury, 2nd Edition
This Reprint compiles recent advances in the understanding and prevention of ischemia-reperfusion injury, a major challenge in modern medicine affecting organs such as the brain, heart, liver, kidney, and lung. This collection highlights the complex interplay between oxidative stress, inflammation, and metabolic imbalance, offering a comprehensive view of current experimental and translational strategies aimed at reducing tissue damage after reperfusion.The contributions in this Reprint explore novel antioxidant and anti-inflammatory approaches, ranging from natural compounds and molecular inhibitors to metabolic interventions and epigenetic modulation. Studies include the use of marine bioactive extracts, the modulation of redox-sensitive signaling pathways, extracellular vesicle-mediated protection, microRNA targeting, intermittent fasting, and complement inhibition.Together, these studies illustrate a paradigm shift from isolated antioxidant therapies toward integrated, multimodal strategies that combine redox control with immune and metabolic regulation. This Reprint provides valuable insights for researchers and clinicians seeking innovative approaches to mitigate ischemia-reperfusion injury across different organ systems and experimental models.
Indian Pharmacy Laws
"Indian Pharmacy Laws: Foundations and Applications" is a seminal work that provides a unified and structured approach to understanding the intricate web of laws and regulations governing the pharmaceutical industry in India. The authors have carefully crafted each chapter to provide not only theoretical knowledge but also practical applications, using case studies, real-world examples, and detailed explanations to make the guide comprehensive and useful. The book covers a wide range of topics, including laws related to the manufacture, licensing, import, export, and sale of medicines, as well as emerging trends, global harmonization efforts, and the impact of evolving technologies and regulations on the industry. By bringing together all relevant topics under one roof, this book aims to empower its readers with the knowledge needed to succeed in the dynamic and highly regulated field of pharmaceuticals in India.
Advanced Image Processing and Computer Vision
Advanced image processing (AIP) and computer vision (CV) remain dynamic and rapidly evolving research areas that drive innovation across a wide range of real-world applications. AI has become a fundamental enabler of AIP and CV, enhancing their capabilities and expanding their impact in multiple domains. While current AI-based algorithms have achieved impressive results through data-driven approaches, many challenges persist, particularly when dealing with limited or low-quality data. These limitations highlight the need for novel methods that are capable of improving accuracy, robustness, and adaptability in complex environments.This Reprint brings together original research articles, comprehensive reviews, and in-depth technical studies focused on the development and application of innovative AI-based algorithms for AIP and CV. It emphasizes emerging approaches that address data scarcity, optimize performance in critical settings, and align with human-centric principles, including ethical and fair AI. Although special attention is given to medical and healthcare applications, the Reprint also reflects the broader relevance of these technologies across agriculture, environmental monitoring, and other applied fields.
Crosstalk Between Autophagy and Oxidative Stress
Autophagy, a fundamental cellular mechanism, plays a pivotal role in maintaining cellular homeostasis by facilitating the removal of damaged organelles and proteins. Autophagy can be activated in response to various stressors, such as nutrient deprivation, hypoxia, drugs, and virus-mediated infections. More and more evidence in recent years indicates that autophagy is a crucial mediator in the regulation of oxidative stress response.We have provided a comprehensive platform for researchers to delve into the cross-regulation between autophagy and oxidative stress. Topics will encompass the molecular mechanisms governing this crosstalk, its impact on cellular functions, and the implications for various diseases, including neurodegenerative disorders, cancer, and metabolic diseases.
Transfusi籀n
In the heart of early 20th century Latin America, where the old world and new collide, a profound exploration of cultural identity and personal transformation unfolds. This historical fiction novel, once lost to time, is now resurrected by Alpha Editions, offering readers an opportunity to delve into the rich tapestry of Spanish literature. As a literary narrative that bridges the gap between past and present, it invites both casual readers and literature students to immerse themselves in a world where human connection transcends the boundaries of language and tradition. The narrative's vivid portrayal of life during a transformative era captures the essence of Enrique de Vedia's works, making it a must-read for those who appreciate the depth and complexity of contemporary Spanish authors. This book, having been out of print for decades, has been meticulously restored for today's and future generations. It is not merely a reprint but a collector's item and a cultural treasure that enriches any classic collection. As Spanish-speaking readers embark on this journey, they will discover the enduring power of storytelling to illuminate the human condition. This edition stands as a testament to the timelessness of its themes and the enduring relevance of its message. Through its pages, the past is not just remembered but vividly brought to life, ensuring its place in the annals of literary history.
La Enferma
In the bustling heart of early 20th century Spain, where the whispers of societal change echo through cobblestone streets, a poignant exploration of the human condition unfolds. This historical Spanish novel, once out of print for decades, now finds its voice again through the meticulous efforts of Alpha Editions. Restored for today's and future generations, it captures the intricate dance between illness and society, revealing the timeless struggle of individuals caught in the throes of cultural transformation. As you delve into this classic literature, you are invited to witness the nuanced portrayal of Spanish urban settings, where the characters grapple with their desires, fears, and the societal expectations that bind them. The narrative, rich with Spanish cultural themes, offers a vivid tableau for literary analysis, making it a compelling read for both casual readers and dedicated Spanish literature enthusiasts. The novel's significance lies not only in its narrative depth but also in its reflection of the era's social dynamics, akin to the works of literary giants like Emilia Pardo Baz獺n and Vicente Blasco Ib獺簽ez. This edition is not just a reprint-it's a collector's item and a cultural treasure, offering a window into a world where personal and societal boundaries blur, inviting reflection on the enduring complexities of human existence.
Neurotoxicity Guidebook
This book was written to inform the educated public about the potential hazards of neurotoxic substances. The impetus for this book was a telephone call in June, 1988, from Mr. Robert Esposito of Van Nostrand Reinhold. He wanted to know if I would be willing to write a book on neurotoxicity that would be suitable for industrial hygienists, safety professionals, occupational health personnel, and others interested in neurotoxicity, including psychologists, neuropsychologists, physicians, risk analyzers, and government regulators.
Control for Epilepsy Suppression
What if we could finally stop epilepsy not by cutting the brain or drowning it in drugs, but by speaking its own mathematical language? This book is the first to treat epilepsy as a pure control-engineering problem. It starts with your brain as a living graph-nodes, wires, white-matter highways-and shows exactly how seizures follow the hidden roads revealed by spectral graph theory and the Laplacian eigenvalue λ₂. It moves into dynamic linear state-space models that let us watch effective connectivity change second by second. Then it dives deep into the famous Epileptor equations, explaining in plain terms how the slow "permittivity" variable z quietly drags the brain across a bifurcation into chaos, and why ordinary EEG misses the vital DC shifts that announce the coming storm. You'll meet Kuramoto oscillators that explain hypersynchrony, Lyapunov exponents that measure the terrifying loss of complexity before a seizure, critical slowing down as nature's universal early-warning signal, Kalman filters that let implants "see" hidden deep foci, network controllability Gramians that reveal which single electrode can rule the whole network, and real optimal-control recipes (LQR, MPC, sparse LASSO control) that stop seizures with the absolute minimum current-protecting both battery and brain tissue. Every chapter gives you the core formulas, biological meaning, and practical ways to turn theory into tomorrow's closed-loop neurostimulators. No other book bridges the gap like this. Popular epilepsy books stay at the patient-story or drug level. Classic neuroscience texts stop at beautiful models but never reach actual control design. Engineering control books ignore the wet, plastic, chaotic reality of brain networks. This one refuses to choose sides: it drags spectral graph theory, bifurcation analysis, phase-locking metrics, chaos measures, and modern network control theory into the epilepsy clinic and shows-step by step, equation by equation-how to build devices that predict, prevent, and gently abort seizures instead of just reacting when it's almost too late. It is written for neurologists who want to understand the math, for engineers who want to save patients, and for researchers who believe the next revolution in epilepsy treatment will be mathematical. (c) 2025 Azhar ul Haque Sario. This book is an independently produced scholarly work created under nominative fair use and fair comment provisions. It has no affiliation with any medical board, university, manufacturer, or regulatory body. All models and methods are presented for scientific and educational
Assistive Technologies in Care and Rehabilitation
This Special Issue showcases recent developments and innovations in assistive technologies for rehabilitation and assistance. Featuring 24 contributions and an editorial, it highlights advances shaping research, clinical practice, and implementation in this field. This collection includes 18 original research articles and 6 reviews.The research articles within present novel solutions, such as neuro-visual adaptive control for robotic surgery, foot-controlled prosthetic arms, smart systems for people with intellectual disabilities, and sensor-based interventions for chronic conditions. These studies demonstrate how robotics, AI, sensors, and virtual reality enhance precision, autonomy, and patient engagement. The review articles analyze existing technologies, covering assistive devices for joints, virtual reality for mobility, robotic hand recovery systems, remote rehabilitation for back pain, stress-reducing technology for children with autism, and air quality monitoring for respiratory diseases. These reviews offer insights into their design, effectiveness, usability, and research gaps to guide future work.Collectively, this Special Issue illustrates the synergy between technological innovation, clinical practice, and research synthesis, offering valuable perspectives for scientists, engineers, and healthcare professionals.I wish to offer my sincere gratitude to all the authors, reviewers, and contributors. Special thanks to the editorial team and Managing Editor, Juicy Yang, for their exceptional dedication and guidance, which were essential to this project's success.
Inflammatory Bowel Disease
Inflammatory bowel diseases (IBDs) are chronic inflammatory intestinal conditions of unknown cause. The main types are Crohn's disease (CD) and ulcerative colitis (UC). Diagnosis typically involves clinical symptoms, laboratory tests, and endoscopic features, along with radiological exams like magnetic resonance imaging (MRI) and computed tomography (CT) enterography, which are crucial for diagnosing and staging CD. CT is effective for evaluating disease activity and complications, such as fistulas and strictures, particularly in acute cases. However, MRI has increasingly replaced CT due to its comparable sensitivity, specificity, and accuracy in diagnosing CD and assessing disease activity without radiation exposure. IBDs require ongoing treatment to manage inflammation and prevent progression. The therapeutic options have expanded significantly with advanced therapies, including biological treatments and small molecules. Nevertheless, surgery remains necessary for complications like abscesses, fistulas, perforation, and strictures, which occur in 48%-52% of CD patients within five years, or for diseases that do not respond to medication. Regular monitoring and therapy adjustments are essential to assess treatment response and identify those needing surgery. This reprint provides information on clinical, diagnostic, and treatment methods for IBDs.
