Toxicity and Human Health Assessment of Air Pollutants
Air pollution has been shown to be responsible for the morbidity and mortality of a variety of major diseases. The World Health Organization (WHO) estimates that almost the whole global population breathes air that exceeds WHO guidelines and contains high levels of pollutants. To date, however, the key constituents of air pollution which impact health and the potential mechanisms remain largely unstudied. In addition, comprehensive assessments of evidence from in vitro and in vivo studies, high-quality cohort studies, and high-resolution model simulations of health impacts are still substantially sparse. Hence, assessing the health risks, identifying the toxic effects, and elucidating the underlying mechanisms are of great importance. This Reprint aims to understand the mechanisms of the health effects caused by air pollution and ensure accurate exposure assessments around ambient environments and inside human bodies, including a range of approaches-from epidemiological cohorts and toxicological studies-to elucidate the linkage between air pollutant exposure and the mechanisms related to health effects. The articles published in this Special Issue can be categorized into four main research directions: elucidating underlying toxicity mechanisms, identifying critical exposure windows and vulnerable populations in epidemiological studies, exploring the impact on postoperative populations, and estimating the association between air pollutant exposure and health effects.
Pots
Postural Orthostatic Tachycardia Syndrome (POTS) is currently defined as a 'syndrome', a collection of symptoms for which the root cause has not yet been identified. This book aims to rectify this by arguing the case for POTS being considered a form of neurological injury to the limbic system following an antecedent trauma, such as a viral illness, pregnancy, surgery or psychological trauma (or a combination). Patrick Ussher himself had POTS but recovered by following a limbic system rehabilitation program (originally developed to treat Multiple Chemical Sensitivity) called the Dynamic Neural Retraining System (DNRS). After recovery, he set about mapping the idea of a limbic system impairment onto pre-existing research into POTS and found that it could explain many key findings including: NET protein deficiency (which is responsible for blood vessel constriction problems and resulting elevated heart rate upon standing), low aldosterone and poor sodium retention (which are responsible for low blood volume problems) and mast cell activation problems. This book will simultaneously act as a guide for those interested in using the DNRS as a treatment for POTS and also as a call for further research into the potential efficacy of the DNRS for treating POTS.
Vagus & Trigeminal Nerve Stimulation
The first and only layperson's guide to both vagus and trigeminal nerve stimulation for Long COVID, dysautonomia, fatigue, brain fog, and more.This book covers what your doctors may not explain: how the vagus nerve and trigeminal nerve (two key regulators of your body's healing systems) can be gently stimulated to help reduce symptoms and support recovery.Inside, you'll find practical answers to questions like: What do the vagus and trigeminal nerves actually do?How does Long COVID damage these nerves-and what symptoms result?Is taVNS (ear stimulation) better than tcVNS (neck stimulation)?What's the safest way to start if I'm sensitive or reactive?How can I use TENS devices at home for nerve stimulation?What's the difference between vagus nerve exercises and actual stimulation?Can vagus nerve stimulation help with anxiety, insomnia, or POTS?What does forehead-based trigeminal nerve stimulation help with?Why do some people feel worse at first-and how do you manage it?Can overstimulation be harmful?How long should I continue using nerve stimulation?Whether you're dealing with Long COVID, ME/CFS, dysautonomia, POTS, MCAS, anxiety, or burnout, this book will help you understand how your nervous system works-and how to support it in healing.
The Myth of Primary Polydipsia
'The diagnosis of compulsive water drinking must be made with care and may represent our ignorance of yet undescribed pathophysiological mechanisms.' - Prof. Daniel Bichet, University of Montreal, 2017.Primary Polydipsia is widely viewed as compulsive over-drinking without physiological cause, often labelled "psychogenic" and linked to mental illness. This book challenges that assumption head-on.Patrick Ussher traces the origins of the diagnosis to early psychiatry and Freudian ideas-hysteria, conversion disorders, sexual repression, childhood trauma-and shows how these psychological assumptions shaped both diagnostic criteria and clinical understanding for decades. Despite advances in medicine, this model has rarely been questioned.Instead, Ussher proposes a new framework: Hypovolemic Dehydration-a physiological condition marked by low blood volume and a thirst mechanism that cannot be satisfied by plain water. This mechanism is seen in illnesses such as ME/CFS, POTS and Long Covid, where patients often drink excessive amounts yet remain thirsty and symptomatic. Could many so-called "psychogenic water drinkers" actually be hypovolemic patients whose real pathology has been overlooked?This book argues that Primary Polydipsia may have been fundamentally misunderstood, placing vulnerable patients at risk of misdiagnosis, stigma, neurological harm and, in rare cases, fatal outcomes. It calls clinicians and researchers to re-evaluate the condition with fresh eyes, grounded in physiology rather than outdated Freudian theory.A compelling and timely challenge to medical orthodoxy-essential reading for nephrologists, endocrinologists, psychiatrists, ME/CFS and POTS researchers, and anyone interested in diagnostic reform.
The Habit Revolution
The health habits you've built up over the years aren't working for you... So it's time to embrace the revolution!Do you feel like you're doing all the right things, but you're still feeling stuck or like your body's determined to work against you?You're not alone. Countless women feel this way and there's a good reason for it.Did you know that almost 80% of all biomedical research is conducted on men or male animals? This means that the vast proportion of what we're told about how to train, eat, sleep, and recover isn't really meant for us-it's meant for the male body. So it's time for a revolution!It's time to get rid of the one-size-fits-all wellness advice and take an approach that fits what you really need-and this much-needed guide will show you exactly how to do it.You're going to discover how your body works and build habits that match your biology instead of working against you, and you're going to find out how to do it throughout every stage of life. Inside this comprehensive guide, you'll find: The 4 pillars of wellness... and clear guidance for building a plan that addresses them all in a way that suits your own personal needsHow to adjust your exercise and nutrition over the month so that it's giving you what you really need during each phasePractical guidance to help you stop chasing who you were and start choosing who you want to becomeAnd much more. This practical guide will be here for you every step of the way... and you're about to step into a whole new world of wellness. Ready for a healthy habit revolution? Then scroll up and click "Add to Cart" right now!
The Habit Revolution
The health habits you've built up over the years aren't working for you... So it's time to embrace the revolution!Do you feel like you're doing all the right things, but you're still feeling stuck or like your body's determined to work against you?You're not alone. Countless women feel this way and there's a good reason for it.Did you know that almost 80% of all biomedical research is conducted on men or male animals? This means that the vast proportion of what we're told about how to train, eat, sleep, and recover isn't really meant for us-it's meant for the male body. So it's time for a revolution!It's time to get rid of the one-size-fits-all wellness advice and take an approach that fits what you really need-and this much-needed guide will show you exactly how to do it.You're going to discover how your body works and build habits that match your biology instead of working against you, and you're going to find out how to do it throughout every stage of life. Inside this comprehensive guide, you'll find: The 4 pillars of wellness... and clear guidance for building a plan that addresses them all in a way that suits your own personal needsHow to adjust your exercise and nutrition over the month so that it's giving you what you really need during each phasePractical guidance to help you stop chasing who you were and start choosing who you want to becomeAnd much more. This practical guide will be here for you every step of the way... and you're about to step into a whole new world of wellness. Ready for a healthy habit revolution? Then scroll up and click "Add to Cart" right now!
Sensors for Physiological Monitoring and Digital Health
The Special Issue, "Sensors for Physiological Monitoring and Digital Health", successfully bridged different scientific disciplines, providing a platform for highly innovative research. The issue showcased the significant potential of health monitoring through physiological signals for personalized healthcare. It highlighted the need for long-term monitoring in both clinical settings, to aid in diagnosis, treatment, and ongoing patient care, and in home settings, to offer continuous remote monitoring, potentially improving health outcomes and reducing healthcare costs. Reliable monitoring of vital parameters like EEG, EMG, and heart rate for elderly and chronic patients, a challenge effectively met by developing continuous, real-time, and nonintrusive wearable, highly integrated sensor networks.The issue captured the rapid growth of the wearable medical device market and the evolution of biosensors and textile-based technologies, driven by advancements in microfabrication, flexible electronics, nanomaterials, and advances in wireless communication. It also explored how physiological monitoring using AI-powered digital health platforms is redefining healthcare, improving the quality of patient personalized care, and delivering value to all stakeholders. This collection of research now stands as a valuable resource, capturing the state-of-the-art in this exciting and emerging field.
Recognitions
Carol Donley & Martin Kohn believe that "physicians stand at a unique vantage point as observers of the human condition." In Recognitions: Doctors and Their Stories, the fourth volume in the Literature and Medicine Series, contributors such as Richard Selzer, Robert Coles, Perri Klass, and Jack Coulehan prove this assertion through their moving and enlightening prose.
The Tyranny of the Normal
Most cultures ostracize people who do not fit within their norms. They pressure abnormal people to change their appearance, fix what bothers other, or stay out of sight--a pressure Leslie Fiedler has named "The Tyranny of the Normal." This anthology examines the experiences of those who live outside social norms for attractiveness, size, and shape; it also explores the reactions of "normal" people to those who seem grotesque. Among the questions raised are who decided what is normal and abnormal; who has the right or authority to decide what efforts, if any, should be made to normalize someone; and who should pay for it--be it plastic surgery or the manipulation of human genes. The first section includes essays and articles written by health care professionals about the treatment of those with eating disorders or physical deformities. Part two contains more than 40 stories, poems, and plays about three main groups of abnormalities: weight, including obesity and anorexia nervosa; height, particularly dwarfism; and deformity or disfigurement. Major writers from Kafka and Poe to Welty and Morrison explore the conflicts of their characters as they struggle with self-image and otherness. One of the purposes of this anthology is to encourage those working or living with others outside the norms to be more inclusive and understanding. They will find this insightful collection a valuable resource.
You Cancer Vive
WARNING: CONTAINS EXPLICIT LANGUAGE - NOT FOR CHILDREN. Let's be honest: cancer is a jerk!You Cancervive is the cheeky, irreverent pep talk that reminds you you're stronger, louder, and far more stubborn than cancer ever expected.This book blends dark humor with real comfort - because sometimes laughter is the only thing stronger than fear.
The Little Encyclopedia of Herbal Medicine
The Little Encyclopedia of Herbal Medicine is your essential home remedies book, offering 100 classic, natural alternatives to common over-the-counter medicines. Designed for quick, intuitive use, this compact herbal medicine book organizes trusted home remedies alphabetically by ailment so you can immediately find the support you need. Inside, you'll discover 50 widely available North American herbs and 100 common remedies for everyday ailments, each paired with clear illustrations that highlight the plant and its active properties. Inside you'll find: 100 Common Remedies for everyday ailments, organized alphabetically for fast lookup50 familiar North American herbs with detailed illustrationsPractical guidance for building a simple, natural home apothecaryEasy-to-follow instructions for creating safe, effective herbal remediesA user-friendly reference ideal for beginners and experienced herbalists alikeWhether you're building a home apothecary, exploring everyday herbal care, or simply want a reliable herbal medicine reference at your fingertips, this indispensable guide makes it easy to apply time-honored herbal remedies around the home.
Physician And Patient
Physician and patient or a practical view of the mutual duties, relations and interests of the medical profession and the community begins by framing medicine as a shared responsibility between practitioner and patient, grounded not in certainty but in thoughtful inquiry. The book questions public expectations of medical infallibility and instead presents healthcare as a discipline shaped by variability, judgment, and evolving knowledge. It critiques the reliance on false remedies and unqualified individuals, highlighting the dangers of quackery and the societal cost of misplaced trust. By drawing comparisons to other scientific fields, it underscores the unpredictable nature of individual responses to treatment and promotes a more nuanced understanding of medical practice. The work encourages ethical engagement, transparency, and education as tools for building trust and reducing harm. Its emphasis on mutual respect and communication outlines a more balanced and conscientious relationship between medicine and the public. The result is a vision of healthcare that values dialogue, responsibility, and continuous learning over rigid prescriptions or hollow authority.
Novel Challenges and Therapeutic Options for Digestive and Liver Diseases
The Special Issue Reprint examines the involvement of ADAMTS13, the von Willebrand factor, and the complement system in the pathogenesis of pre-eclampsia/HELLP syndrome.Furthermore, this Reprint determines the characterization of the hemodynamic profile of patients with liver cirrhosis undergoing liver transplantation with the help of the PiCCO system during the three surgical stages, the impact of bleeding on hemodynamic status.Moreover, this reprint investigates the positive effect, if any, of adipose-derived mesenchymal stem cells mixed with platelet-rich plasma in the healing of bowel anastomoses in an inflammatory environment after the establishment of experimental colitis. Also, this reprint compares side-by-side placement and partial stent-in-stent placement in unresectable hilar malignant biliary stricture cases with uncovered metal stent placement in two branches of the intrahepatic bile duct.Furthermore, this Reprint intends to investigate the clinical and survival features of esophageal adenosquamous carcinoma.
Physical Activity for Psychological and Cognitive Development
Physical activity has multiple benefits for cognitive function, psychological variables, social skills and health, among other factors. The latest research and scientific studies reflect the evolution of and growing interest in this area. Even so, we must continue to advance the research on this topic. The aim of this Special Issue is to disseminate high-quality research related to cognitive and psychological development through physical activity. These original research articles deepen and expand our understanding of the role of physical activity in relation to cognitive performance, psychological variables and physical, mental, and psychosocial health.
Risk Factors and Prevention of Cardiovascular Diseases
This compilation, originating from the Special Issue "Risk Factors and Prevention of Cardiovascular Diseases", presents a collection of recent research articles as well as reviews and meta-analyses focusing on the assessment of cardiovascular risk factors and original approaches to preventive action. This is important, as cardiovascular diseases still remain the leading causes of premature mortality worldwide, representing the most common non-communicable diseases (NCDs). The comprehensive discussion of the bench-to-bedside approach conducted herein enables us to understand the importance of various experiments in medicine, including laboratory and biochemical tests identifying values such as albumin and aldosterone concentrations, in addition to the significance of imaging techniques, such as magnetic resonance, as powerful diagnostic tools for cardiovascular diseases. Readers will encounter numerous interesting explorations into the influence of obesity, hypertension, sedimentary lifestyles, smoking habits, and physical exercise on health status. Studies in this collection evaluate the role of pre-workout supplements in cardiovascular heath, reviewing the current knowledge regarding their effectiveness. Moreover, the divergencies in cardiovascular risk factors based on ethnicity are also discussed.Eventually, this volume may serve as a source of ideas for primary and secondary prevention techniques, playing a role in diminishing the mortality rate of cardiovascular diseases. Furthermore, addressing the issues of treatment adherence and compliance in the prevention of cardiovascular diseases is of great value.
Newborn Screening for Congenital Hypothyroidism
Newborn screening (NBS) for congenital hypothyroidism (CH) began in the 1970s and has prevented countless cases of intellectual disability through early detection and treatment. Yet, nearly 70% of newborns worldwide still lack access to CH screening. Despite over fifty years of experience, important questions remain about screening algorithms, genetic causes, and optimal follow-up care. This Special Issue reprint of the International Journal of Neonatal Screening brings together contributions from ten countries, addressing topics such as testing strategies, screening in low- and middle-income countries, premature infants, and rare or central forms of CH. Together, these papers highlight global progress in CH screening and the continuing need to expand access and refine practice to ensure every newborn benefits from early diagnosis and treatment.
Human Poliovirus
Polio eradication is the global effort to permanently eliminate poliovirus and the disease it causes, poliomyelitis. The Global Polio Eradication Initiative (GPEI) leads this effort. While wild poliovirus cases decreasing by over 99% since 1988, the job is not yet finished. Key aspects of polio eradication include the following: Ensuring high immunization coverage with oral polio vaccine (OPV) and inactivated polio vaccine (IPV). Robust surveillance systems, including acute flaccid paralysis surveillance to detect and respond to poliovirus circulation.Assuring polioviruses are not stored in laboratories.Rapid and effective responses to outbreaks, including vaccination campaigns.Significant funding from various sources.Only Pakistan and Afghanistan remain endemic for wild poliovirus.Two of the three wild poliovirus serotypes (Types 2 and 3) have been certified as eradicated.The Goal of Polio Eradication: Achieve a world free of all forms of poliovirus, including both wild and vaccine-derived strains.
30 Needles Constellation Acupuncture
My introduction to acupuncture began with my wife, Angela. She took me to a renowned acupuncturist in West Germany, who was not only highly sought after in acupuncture but also a distinguished professor, lecturing on acupuncture and traditional medicine at the Medical University of Frankfurt in West Germany. For the first time, I personally experienced the remarkable effects of acupuncture needles. I was amazed and astonished by the significant and profound impact of acupuncture on my body. After my first acupuncture, I felt renewed in my body, mind, and soul. I also notice that the needles activated my body's self-organizing system. My minor skin cuts healed much quicker, and my dentist told me that my gums looked their best, with no signs of inflammation.Feeling moved and grateful, I began my transformation from an internal medicine specialist to a holistic cardiologist, fully trained in acupuncture. We went to China and had the privilege to be trained in the 1990s by Dr. Li of the Xuan-Wu Hospital, a prominent member of the Beijing School of Acupuncture. His introduction of the 30 Needles Constellation Acupuncture, a technique of the strategic placement of 30 acupuncture needles on specific points of the body, marked a transformative moment in the integration of my modern and traditional medical knowledge. It has challenged me as an established medical doctor and specialist but also opened my inner eye to this acupuncture technique, which cannot be found in conventional textbooks. The core needle techniques, a key aspect of these healing methods, were traditionally transmitted orally. Over time, I have observed that all conditions I have treated at the 30 Needles Constellation Acupuncture showed great improvement and more often, a spectacular healing.
Dementia Man
A powerful memoir of resilience, love, and redefining life after an Alzheimer's diagnosis.After decades as a tireless advocate for justice and social change, Samuel A. Simon faces the most personal fight of his life: the slow, undeniable progression of cognitive decline. When the diagnosis of Alzheimer's disease comes, he refuses to fade quietly.Based on his award-winning play Dementia Man, this deeply personal memoir invites readers into Simon's "existential journey"-a story told with candor, courage, and an unflinching look at a broken medical system. As he revisits pivotal moments from his past and navigates the daily challenges of neurocognitive disease, Simon offers an intimate portrait of a man determined to shape his own future, even as the disease seeks to define it.Both moving and urgently important, Dementia Man is changing the conversation about Alzheimer's in America. It's a story of hope and defiance that challenges us all to imagine a future of dignity, connection, and purpose for the millions living with cognitive decline.
Cochlear Implant Basics, What a Candidate for a Cochlear Implant Needs to Know
Cochlear Implant Basics: What a Candidate for a Cochlear Implant Needs to Know is designed as both a guide and a companion. For many, the suggestion of a cochlear implant can be overwhelming-even frightening. Author Richard Pocker's goal is to dispel misconceptions, answer common questions, and provide a clear path through what can often feel like uncharted territory. Within these pages, you'll find the transcripts of twenty-five podcast interviews, rehabilitation exercises used after surgery and activation, and a carefully curated list of resources. Together, these resources form a roadmap for anyone considering or beginning the cochlear implant journey. Above all, Cochlear Implant Basics is about hope and connection. A cochlear implant can restore not only speech comprehension and awareness of environmental sounds but also the joy of music, the ease of a phone call, and the simple yet profound gift of participation in daily life. This book's objective is to reach those "sitting on the fence" and encourage them to step forward-to leave the isolation of deafness behind and rediscover the fullness of living.
Doctor Magnate
Doctor Magnate is the powerful, real-life journey of a small-town boy who dared to dream beyond his circumstances. From working in a crockery store to walking the streets of Kota with faith and hunger, from missing coaching due to financial constraints to finally wearing the white coat of his dreams, this book is a living example of how purpose, and gratitude can turn struggle into strength. Through deeply personal reflections, the author unveils the mindset behind every milestone: how to transform pain into purpose, build financial and emotional stability as a professional, and rise from being just a doctor to becoming a Doctor Magnate-a visionary who heals, leads, and builds. Each chapter is a blend of inspiration, practicality, and transformation, guiding medical students, professionals, and dreamers toward mastery of their craft, their mindset, and their money. If you've ever felt stuck between service and success, this book will show you how to live both with integrity, impact, and inner peace.
The Body Remembers to Breathe
What if the fastest way to calm your anxiety isn t in your mind but in your breath? In a world overloaded with information and overstimulated by stress, breathwork for anxiety offers something rare: immediate access to inner safety. This book is a science-backed, deeply practical guide to using your own breath to regulate your nervous system, interrupt spirals of fear, and prevent panic before it begins. Whether you re navigating panic attacks, chronic unease, or high-functioning anxiety, this is not another collection of vague breathing tips. It s a precision tool. You ll learn how specific breathing patterns like conscious breathing for anxiety, breathing techniques for panic attacks, and the art of gentle exhalation speak directly to your brain s survival systems. Through engaging stories, actionable protocols, and insights from neuroscience and trauma research, this book helps you: Understand the physiological signs of anxiety and how they hijack your breath Interrupt panic in real-time with body-based tools Rebuild trust in your nervous system using anxiety breathing exercises Explore how culture, trauma, and identity shape your breath and baseline safety Create a personalized practice using breathwork for emotional healing This is for the thinker who can t outthink their fear. For the body that remembers what the mind tries to forget. For anyone ready to shift from reactivity to regulation using the one tool always within reach. If you re searching for real, grounded methods to stop a panic attack naturally, stabilize your emotions, and reconnect with your body, this guide is your next breath. The science is clear. The body knows what to do. You just have to breathe.
Beyond Precision
What if the system that knows your body best still doesn t understand who you are? This provocative, eye-opening book reveals the hidden tension at the heart of today s healthcare revolution: as artificial intelligence makes personalized medicine more precise, it risks making care less human. Behind the promises of faster diagnoses, custom treatments, and optimized outcomes lies a powerful blind spot our growing dependence on AI in healthcare systems that can predict disease but overlook identity, values, and context. Perfect for patients, clinicians, technologists, and anyone caught between the hope and hype of digital health systems, this book cuts through the noise. It s not a celebration of smart machines or a dystopian warning it s a deeply thoughtful exploration of what real care means when machine learning in medicine begins to shape not just our treatments, but our choices, autonomy, and trust. Inside, readers will uncover: - How algorithmic bias in healthcare silently shapes diagnostics and outcomes - Why ethical AI in medicine must go beyond data privacy to consider dignity and meaning - The emotional toll of being reduced to a risk profile in the age of personalized healthcare - How clinicians are navigating the clash between expertise and automation - What it will take to restore patient autonomy and AI balance in future care With insight drawn from philosophy, cultural analysis, and real-world medical cases, this book equips readers to ask better questions about the future of care and to demand systems that don t just see the body, but also hear the story. If you're looking for a guide that challenges assumptions, exposes blind spots, and reframes the future of healthcare and machine learning, this is the book you ve been waiting for.
The 5-Minute Body
Feeling too busy to get fit? You don t need marathon gym sessions, expensive memberships, or punishing diets to build lasting strength, energy, and health. This book reveals how 5 minute workouts and simple daily actions backed by science can deliver real results without overhauling your life. Discover the power of micro workouts no equipment, subtle NEAT daily movement that burns calories without formal exercise, and habit-based fitness plans designed for real-world schedules. Learn how to integrate office desk exercises, breathing techniques for endurance, and sleep for recovery fitness into your day so that staying healthy feels effortless, not overwhelming. Perfect for busy professionals, parents, and anyone tired of starting and abandoning fitness programs, this approach meets you where you are whether that s between meetings, on a lunch break, or before the kids wake up. By focusing on consistency over intensity, you ll see how small wins compound over time, building not only a stronger body but also the confidence and energy to do more of what you love. Inside, you ll find: Quick, targeted routines for home, office, or travel Easy food swaps that fuel you for the long term and support sustainable weight loss routines Recovery and mindset strategies that make health a habit instead of a chore The result? A system that adapts to your life, rather than forcing your life to fit a program. No more all or nothing cycles just steady, achievable progress that lasts. Start small, stay consistent, and watch how a few intentional minutes each day can change everything.
Marine Anti-Inflammatory and Antioxidant Agents, 4th Edition
Inflammation is a natural biological response to harmful stimuli like pathogens, injuries, or environmental stressors. However, when this response becomes chronic-often due to modern lifestyle factors like poor diet-it can lead to "lifestyle diseases". A wide range of chronic conditions, including cardiovascular diseases, cancer, diabetes, chronic kidney disease, non-alcoholic fatty liver disease, neurodegenerative, and autoimmune diseases, are now linked to inflammation. These conditions often involve oxidative stress, a harmful state caused by an imbalance between reactive oxygen and nitrogen species (ROS and RNS) and the body's antioxidant defenses. Oxidative stress can further drive inflammation, creating a damaging cycle.The rising prevalence of chronic inflammatory disease has sparked interest in natural compounds with both antioxidant and anti-inflammatory effects. Marine organisms have emerged as a promising source of such bioactive compounds. From marine plants, algae, and fish to invertebrates like sea cucumbers, sponges, and soft corals and microorganisms such as fungi, microalgae, and archaea, these ocean lifeforms produce a wide array of therapeutic compounds. Given the growing scientific and therapeutic interest in marine bioactive compounds, we are pleased to launch the fourth edition of the Special Issue "Marine Anti-Inflammatory and Antioxidant Agents."
MSM Therapy Handbook
Discover the Natural Solution to Joint Pain, Inflammation, and Chronic Discomfort-Without Prescription Drugs or Side EffectsStruggling with arthritis, joint pain, or chronic inflammation? Tired of medications that don't work or cause unwanted side effects? MSM Therapy Handbook is your complete, evidence-based guide to harnessing the power of Methylsulfonylmethane (MSM) for natural pain relief and lasting joint health.Unlike generic supplement guides, this practical manual provides step-by-step protocols you can start today-no guesswork, no confusion, just clear instructions tailored to your specific health needs.What You'll Get Inside: - Progressive Dosing System - Know exactly how much MSM to take on Day 1, Week 2, and beyond with a proven 4-phase protocol that eliminates trial-and-error- 20+ Condition-Specific Protocols - Targeted plans for arthritis, fibromyalgia, athletic recovery, back pain, tendonitis, and more-each with precise dosing, timing, and expected results- 21-Day MSM Reset Program - A complete done-for-you plan you can implement immediately for fast, noticeable improvements- MSM Synergy System - Discover which supplements amplify MSM's effectiveness (and which ones to avoid)- Troubleshooting Guide - Fix side effects, overcome plateaus, and optimize results with the MSM Symptom-Solver Matrix- Quality Buying Guide - Learn to identify premium MSM products and avoid low-quality supplements that waste your moneyPerfect For: - Anyone seeking natural alternatives to NSAIDs and prescription pain medications- Arthritis and joint pain sufferers looking for drug-free inflammation management- Athletes wanting faster recovery and injury prevention- Health-conscious individuals preventing age-related joint deterioration- Anyone who tried MSM before without success and needs expert guidanceStop suffering in silence. Whether you're dealing with osteoarthritis, rheumatoid arthritis, sports injuries, or general inflammation, this handbook provides the exact protocols used by thousands to reclaim their mobility and quality of life.No medical jargon. No vague advice. Just practical strategies that work.Transform your approach to joint health and pain management with proven MSM therapy protocols. Your journey to natural pain relief starts here.The information in this book is for educational purposes only and is not intended as medical advice. Always consult your healthcare provider before starting any new supplement regimen. Individual results may vary.
Wired Through the Gut
What if your anxiety wasn t all in your head but in your gut? What if the foggy moods, unexplained sadness, or chronic stress weren t psychological flaws, but symptoms of an unseen system quietly malfunctioning beneath your ribs? This groundbreaking book uncovers the science behind the gut brain connection revealing how your digestive health is intimately wired to your emotional well-being. Drawing from cutting-edge research in microbiology, neuroscience, and integrative medicine, it explores how gut health and anxiety, depression, and even memory are linked through a powerful, two-way communication network known as the gut-brain axis. Whether you struggle with mood swings, brain fog, IBS, or burnout, this book offers a clear, evidence-based path forward. Learn how your microbiome and mental health are shaped by everyday factors from diet and antibiotics to stress and sleep and how healing your gut can support emotional resilience. Inside, you'll discover: The surprising role of psychobiotics for depression and how certain bacteria can boost mood How the vagus nerve acts as a real-time translator between your belly and brain The connection between inflammation and emotional health, and what to do about it Practical insights into foods that heal and foods that affect mood Perfect for readers curious about how digestion affects mental health, this book doesn t just explain the science it empowers you to use it. Whether you're a wellness seeker, a mental health professional, or someone who s tried everything and still feels off, this is your invitation to listen to the body s second brain and finally feel better from the inside out.
Parkinson's Stories
A delightful collection of Parkinson's stories from first diagnosis to brain surgery and creative cures.Contributions from South Africa, Canada, the Netherlands, America, and many parts of the UK inform, entertain, and enlighten readers about this universal ailment.In his Foreword, Professor Miratul Muqit speaks of the need for the medical profession to hear the responses and listen to the concerns of Parkinson's sufferers. This book is essential for all newly diagnosed cases. It explains how we adapt to our illness.'I have learned and continue to learn that each person is vital for determining treatment options to maximise response and quality of life. We also know a great deal more about the underlying biology that explains why brain cells in Parkinson's may succumb with a promise of new treatments that could slow the disease that has to date remained elusive.'- Professor Miratul Muqit, Dundee University
Magic on Mira Road
In the 1980s, four young medical school students felt the need to provide fr ee, holistic care for the millions of impoverished people in their hometown ofMumbai. They stepped into Mumbai's slums with nothing more than a mat, a few medicines, and a sacred song. From those humble beginnings grewBhaktivedanta Hospital-now a 300-bed, state-of-the-art hospital and researchcentre serving thousands with compassion for the body, mind, and soul.Magic on Mira Road takes you inside this extraordinary hospital-wherepatients don't want to be discharged, staff members don't want to go home atthe end of their work day, and managers lead with heart. You'll read stories ofsorrow, triumph, love, and spirituality. Along the way, you'll also get a glimpseinto the universal spiritual principles of the bhakti-yoga tradition that inspireit all. You will witness a radical vision of healthcare that has the power totransform lives, and the world. You will experience at least some of the magicthat is the Bhaktivedanta Hospital.
Staying Fit While You Sit
Is pain impeding your progress? Are you too tired to write another page? Ready to get healthier and more productive?If you're like most authors, you've struggled with aches and pains, unbalanced nutrition, eye strain, and more. The longer we sit working on our craft, the more these problems crop up. But you don't have to sacrifice your health, energy, or focus to stay productive.Staying Fit While You Sit is a practical guide that shows you how to: ✅ Add movement into your day with simple, desk-friendly exercises✅ Boost mental clarity and stamina to stay in creative flow✅ Eat healthier on a busy schedule with nutrition tips for writers and busy professionals✅ Design your workspace for comfort, focus, and long-term wellness✅ Balance work and life with easy, healthy hacks✅ Protect your body & mind from the hidden toll of a sedentary lifestyleWhether you're a writer, freelancer, entrepreneur, or creative thinker, this book gives you the tools to stay healthy, focused, and inspired.Stay productive. Stay healthy.Stay Fit While You Sit.
The Great American Medical Show
What happens when a seasoned physician pulls back the curtain on America's health care system?Dr. Bernard M. Patten has lived medicine from every angle: patient, doctor, advocate, and critic. With wit, candor, and unflinching honesty, he takes readers on an eye-opening journey through decades of encounters that reveal both the brilliance and the failures of modern medicine.From the golden age of doctor-patient trust to today's labyrinth of insurance denials, inflated costs, over-testing, and medical quackery, Patten exposes a system where profits too often come before patients. Along the way, he shares vivid stories about hospitals, doctors, insurance companies, and the people caught in between.This book is a call for clarity, skepticism, and empowerment. Readers will come away better prepared to navigate the complexities of American healthcare, armed with knowledge, perspective, and a critical eye. If you want to understand what went wrong with the most expensive health care system in the world, The Great American Medical Show will inform, provoke, and inspire.
Invisible Illness
"An incisive study that illuminates the myriad complexities of chronic illness."-Kirkus Reviews (Starred Review)"Movingly spotlights the struggles of chronically ill patients."-Publishers WeeklyA moving cultural history of disability-and a powerful call to action to change how our medical system and society supports those with complex chronic conditions From lupus to Lyme, invisible illness is often dismissed by everyone but the sufferers. Why does the medical establishment continually insist that, when symptoms are hard to explain, they are probably just in your head? Inspired by her work with long COVID patients, medical anthropologist Emily Mendenhall traces the story of complex chronic conditions to show why both research and practice fail so many. Mendenhall points out disconnects between the reality of chronic disease-which typically involves multiple intersecting problems resulting in unique, individualized illness-and the assumptions of medical providers, who behave as though chronic diseases have uniform effects for everyone. And while invisible illnesses have historically been associated with white middle-class women, being believed that you are sick is even more difficult for patients whose social identities and lived experiences may not align with dominant medical thought. Weaving together cultural history with intimate interviews, Invisible Illness upholds the experiences of those living with complex illness to expose the failures of the American healthcare system-and how we can do better.
Surfing the Covid Waves
A group of blind men encounter an elephant for the first time and try to understand it by touch. Each man feels a different part: one the trunk, another the leg, another the ear, and conclude that the elephant is like a snake, a tree, and a fan, respectively. They argue, each believing their perception is correct. A wise man intervenes, explaining that they each have grasped only a part of the whole. The story teaches that individual perspectives can be limited and incomplete. Anjan Kr. Dasgupta joined Kalyani University in 1985 and retired as a UGC professor from the Department of Biochemistry at Calcutta University in 2017. He chaired the department for two years. He has four decades of experience in research and teaching in multidisciplinary domains spanning biophysics, biochemistry, and nanoscience. He has over 170 papers in international journals, has guided over 20 PhD scholars, and holds over a dozen international patents. Prantar Chakrabarti, a graduate of Medical College Kolkata, is a distinguished haematologist with an MD from IPGMER, a DNB in Internal Medicine, and a DM in Clinical Haematology from AIIMS New Delhi. Formerly the Professor and Head of Haematology at NRS Medical College Kolkata, he played a crucial role in establishing the Institute of Haematology and Transfusion Medicine at Medical College Kolkata. Currently, he collaborates with Zoho Corporation to develop affordable rural healthcare models.
Fix Your Body Mechanics
This is the first of three workbooks to accompany Section I of Fix the Fire Damage - Your go-to guide when pain first strikes (The Everyday Pain Guide #2). Get the guidance you need to work through your Body Mechanics Action Plan and track your progress. Learn to use your body movement, positioning and gentle action to help you through acute episodes of surprise pain that hits you in the middle of the night, on weekends or holidays when seeing your providers is not possible.Find ways to create ease in the moment, thereby transforming the intensity and trajectory of your pain experience. This process will also give you the tools you need to help your providers to better help you.For best results, make sure to seek care as soon as possible and/or in conjunction with these strategies. Always check with a healthcare provider first.Readers are encouraged to use these workbooks in conjunction with both Volumes 1 and 2 in the Everyday Pain Guide series. Find or request a workshop near you by reaching out at www.ya-Ling.com. For personalized guidance, on-demand virtual live coaching is also available.It's okay to pay attention to your pain and relief is possible.
Fix Your Body Chemistry
This is the second of three workbooks to accompany Section II from Fix the Fire Damage - Your go-to guide when pain first strikes (The Everyday Pain Guide #2). Get the guidance you need to work through your Body Chemistry Action Plan and track your progress. Learn about your pain and inflammation triggers as you explore what to add to or avoid in your food and environment for lower overall body inflammation.Find ways to better cope with your pain, ease it and keep it from coming back, while also gaining information about your situation that can help your providers better help you.Readers are encouraged to use these workbooks in conjunction with both Volumes 1 and 2 in the Everyday Pain Guide series. Find or request a workshop near you by reaching out at www.ya-Ling.com. For personalized guidance, on-demand virtual live coaching is also available.It's okay to pay attention to your pain and relief is possible.
Fix Your Stress Biology
This is the third of three workbooks to accompany Section III from Fix the Fire Damage - Your go-to guide when pain first strikes (The Everyday Pain Guide #2). Get the guidance you need to work through your Stress Biology Action Plan and track your progress.Learn how to release your emotional stress triggers, retrain your nervous system and reinforce low stress biology for lower overall body inflammation.Find ways to better cope with your pain, ease it and keep it from coming back, while also gaining information about your situation that can help your providers better help you.Readers are encouraged to use these workbooks in conjunction with both Volumes 1 and 2 in the Everyday Pain Guide series. Find or request a workshop near you by reaching out at www.ya-Ling.com. For personalized guidance, on-demand virtual live coaching is also available.It's okay to pay attention to your pain and relief is possible.
How to Live Disease-Free with Superfoods
Do you know that superfoods can help you prevent and manage chronic disease? Over the years, we have been repeating the same eating mistakes that our parents made. This is the reason why the prevalence of chronic diseases like diabetes, high blood pressure, and arthritis is increasing in the population over time. In How to Live Disease-Free with Superfoods, research scientist and registered pharmacist La Fonceur tells you how foods that act like medicines can naturally prevent and control diseases. With superfoods, you can develop your body in such a way that you do not need medicines even at the age of 40, 50, 60 or 70. You will learn how you can avoid disease even if someone in your family has a history of that disease. You will also learn in-depth how to control chronic diseases such as diabetes, hypertension, arthritis, and many other conditions with superfoods. Certain foods become more nutritious when combined with other foods. In this book, you will get to know about the ideal nutrient combinations that you should eat for maximum health benefits. Get ready for a healthier tomorrow.
Liver Fibrosis
Fibrosis is a double-edged sword. On one hand, it can be the final stage of healed inflammation as scar tissue. On the other hand, it is often linked to a decrease in organ function or complete organ failure. Additionally, in liver disease, fibrosis serves as an indicator of disease progression towards liver cirrhosis or hepatocellular carcinoma. This is particularly true for non-alcoholic fatty liver disease, a widespread disorder associated with Western lifestyles and diets. To interfere with organ fibrosis, it is crucial to have a better understanding of its initiation, perpetuation, and resolution at the molecular level. The development of liver fibrosis can be caused by metabolic factors (such as alcohol, diet, and drugs), infections (such as viruses), autoimmune conditions (like primary biliary cholangitis), or genetic abnormalities (such as increased iron storage). The molecular pathways that lead to advanced fibrosis vary depending on the underlying cause. The goal of this Special Issue is to dissect these processes and provide more clarity on the subject.
Nutrition and Growth of Preterm Neonates during Hospitalization
This Reprint, entitled Nutrition and Growth of Preterm Neonates during Hospitalization: Impact on Childhood Outcomes, compiles recent studies on the nutrition and growth of premature neonates and their implications for neurodevelopment and long-term health. It examines the multifactorial causes of suboptimal postnatal growth, such as feeding challenges, gut immaturity, high energy demands, respiratory and infectious complications, and rapid brain development. The collection also addresses controversies regarding the definition of extrauterine growth retardation and what constitutes optimal nutrition and growth with the least adverse impact in later life. By bringing together original research and reviews, this Reprint provides valuable insights into nutrition, growth monitoring, developmental outcomes, and the long-term health of preterm populations.
Artificial Intelligence in Public Health
The COVID-19 pandemic accelerated AI adoption in healthcare, highlighting its potential in diagnostics, patient care, and resource management. This reprint presents a collection of articles, reviews, and other contributions spanning oncology, cardiology, mental health, imaging, and public health. It showcases the latest advances in AI applications, interdisciplinary approaches, and innovative strategies shaping the future of healthcare.
Recent Advances in Acetaminophen Hepatotoxicity
Acetaminophen (paracetamol, APAP) is one of the most consumed analgesic and anti-pyretic drugs in the world. Generally considered safe at therapeutic doses, intentional or unintentional overdosing can cause severe liver injury and even acute liver failure. In Western countries, APAP is responsible for thousands of hospitalizations annually and is the major cause of acute liver failure. Since the establishment of the clinically relevant mouse model in 1973, numerous studies investigating the mechanism of APAP-induced liver injury have been published. Based on early mechanistic insight, the current standard of care, N-acetylcysteine (NAC), was developed. Although NAC is still the only clinically approved antidote available, additional mechanistic insight led to the discovery of promising new drugs, such as fomepizole, which, based on the solid understanding of its mechanism of action and proven safety profile, is under clinical development. Further drugs or compounds with various modes of action are also under consideration as future antidotes. In addition to the intracellular mechanisms of injury, the inflammatory response, which can aggravate the injury or promote regeneration and recovery, is another focus of research. However, no viable drug candidates promoting regeneration have been identified. This Special Issue is aimed at providing selected contributions on advances in the mechanistic understanding of APAP-induced liver injury and the regeneration and identification of new therapeutic targets and interventions.
Geriatric Fracture
This Reprint collates recent advances in the field of geriatric trauma, with a particular focus on the surgical and nonsurgical management of fractures in older adults. As populations age worldwide, the incidence of fragility fractures and the complexity of care for frail and multimorbid patients continue to increase. Contributors to this Reprint examine current practices in trauma and orthopedic surgery, the role of multidisciplinary care, and the challenges of optimizing outcomes while balancing risks of complications.Topics covered include innovations in fracture management, perioperative decision-making, management of comorbidities, strategies for prevention of secondary fractures, and emerging approaches in frailty and osteoporosis care. By combining perspectives from geriatric medicine, trauma surgery, orthopedic surgery, and rehabilitation, the Reprint highlights the importance of integrated care pathways that improve recovery and quality of life for older adults.This collection is intended for clinicians, researchers, and policy makers interested in the evolving landscape of geriatric trauma care. It offers both clinical insights and a foundation for further research aimed at strengthening evidence-based and patient-centered approaches in this growing field.
Extracellular Vesicles and Exosomes as Therapeutic Agents
This reprint aims to evaluate the therapeutic potential of extracellular vesicles (EVs) and exosomes (EXs), with an emphasis on recent developments in their engineering and medical applications. Genetic engineering and chemical modifications of EXs, combinatorial methods-such as hybrid nanoparticles-large-scale EX production, and the potential of EXs derived from plants and milk as drug delivery vehicles comprise recent advancements in therapeutic applications. The research presented in this reprint examines the antimicrobial properties, regenerative potential in spinal cord injuries, and maternal-fetal communication functions of EXs. The literature highlights the dual role of EXs in Parkinson's disease, acting as both mediators of disease progression and potential therapeutic agents. Additional research examines the effects of EXs induced by exercise, the effectiveness of EXs derived from plants in the treatment of cancer, and the application of lyophilized EXs for recovery from brain injuries. As therapeutic agents, EVs and EXs are gaining popularity. This reprint highlights the need for continued research to maximize their production and use in clinical settings.
Design and Synthesis of Novel Antibiotics
The increasing resistance of microorganisms to currently available antimicrobial agents represents a serious and growing global health concern. Antimicrobial resistance (AMR) arises naturally over time, driven by selective pressure associated with the extensive use of antimicrobial compounds. Genetic mutations and adaptive mechanisms allow sensitive microorganisms to acquire resistance, with bacterial pathogens showing particularly alarming trends-especially the rapid emergence and dissemination of multidrug-resistant (MDR) and pan-drug-resistant (PDR) strains.This phenomenon is exacerbated by the widespread use of antibiotics in clinical therapy, agriculture, and the food industry, contributing to the environmental accumulation of antimicrobial residues and further promoting resistance. As a result, there is an urgent need to develop novel antibiotics with alternative mechanisms of action and improved safety profiles.This Reprint presents recent advances in the design, chemical synthesis, and structural characterization of new antimicrobial agents. Emphasis is placed on the evaluation of their biological activity and cytotoxicity. The Special Issue includes both original research articles and review papers, offering valuable insights into current strategies aimed at overcoming antimicrobial resistance.
10th Anniversary of Biomedicines
Advances in Multiple Sclerosis celebrates the 10th anniversary of Biomedicines. This Special Issue is a collection of remarkable papers addressing, among others, genetic markers, the multifactorial etiology of MS, the inflammatory contribution of the tertiary lymphoid structures, T-cell receptors, neurogenic bladder dynamics, and health disparities among minorities in the US. This collection constitutes an excellent source of information for interested MS researchers and professionals.
The Complete Long COVID Handbook
The Long COVID Handbook, Volume 7: Hormone Imbalance and Metabolic DisruptionPersistent fatigue, brain fog, irregular cycles, or unexpected menopausal symptoms after COVID can be signs of a deeper hormonal disruption. Long COVID is known to affect the endocrine system, leading to thyroid, adrenal, and metabolic imbalances that leave many people looking for answers.In this volume, Dr. Robert Groysman explains how post-viral inflammation interferes with key hormones such as estrogen, progesterone, thyroid, cortisol, and insulin. You'll discover how these changes drive symptoms like exhaustion, mood swings, and weight fluctuations. The book outlines why conventional care often falls short and offers a step-by-step framework for restoring balance through targeted hormone support and metabolic healing.Readers will learn how to evaluate their thyroid and adrenal function, explore safer approaches to hormone replacement, and support recovery through improved sleep, nutrition, and stress regulation. Each chapter includes practical strategies and testing guidance that can be shared with a healthcare provider to personalize treatment.Written for those experiencing post-COVID fatigue, menstrual disruption, or metabolic changes, this handbook empowers readers to understand their symptoms and take informed action. It provides a roadmap to restore vitality, stability, and long-term health through hormonal recovery.Take the next step toward balance and energy with The Long COVID Handbook, Volume 7.
Healthy and Safe Environments across Occupational and Environmental Contexts
This Special Issue, "Healthy and Safe Environments across Occupational and Environmental Contexts", brings together research that is at the interface between environmental and occupational health. According to the WHO, environmental health encompasses the assessment and control of physical, chemical, and biological factors that are external to individuals, as well as behavioral determinants that can impact health. The workplace often mirrors the general environment: hazards may share common origins, and effective control strategies can be applied across both contexts. Skills and knowledge used to address environmental risks are frequently the same as those required for occupational hazards. The contributions gathered in this Issue illustrate the richness and relevance of this interdisciplinary field. They span novel approaches to hazard identification and risk assessment, investigations of exposures and health outcomes, and analyses of physical, chemical, and psychosocial factors. Several studies deepen our understanding of the subtle and long-term health impacts of environmental pollutants, including air pollution and endocrine-disrupting chemicals. Others highlight the implications of occupational exposures, ranging from noise and stress to laboratory-specific risks, while also addressing workplace health promotion in diverse cultural contexts.
