The Soldier's Manual of Sanitation
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Chronic Bronchitis
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An Anatomical Dissertation Upon the Movement of the Heart and Blood in Animals
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Notes on Hospitals
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PCR Primer Design
This third edition provides new and updated chapters on design PCR primers for successful DNA amplification. Chapters are divided into seven parts, including primer design strategies for quantitative PCR, genotyping, multiplex PCR, in silico PCR primer design, and primer design to identify plant and animal viruses. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, PCR Primer Design, Third Edition aims to be useful for various fields of molecular biology, including biotechnology, molecular genetics, and recombinant DNA technology.
Pathogenesis of Systemic Lupus Erythematosus
The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature.This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.
Paediatrics in the Reichsuniversitat Straaburg
Examines the experience of paediatric patients, and the staff who determined their treatment, in the Reichsuniversitat Strasbourg, a Nazi-run hospital in occupied France from 1941 to 1944.
From Under the Cloud
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Doctor Robert Child
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An Anatomical Dissertation Upon the Movement of the Heart and Blood in Animals
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A Voyage of Discovery
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Universal Arithmetick
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Transcatheter Structural Heart Disease Interventions
This reprint focuses on the transcatheter treatment of the main structural heart diseases covering the latest innovations and hot topics on this subject. All the technological developments witnessed in recent decades have made structural heart disease interventions a growing field and have contributed to offering patients less invasive, more effective, and safe alternative approaches.
Technical Methods of Analysis as Employed in the Laboratories of Arthur D. Little, inc., Cambridge, Mass.
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A Treatise on Ancient Armour and Weapons, Illustrated by Plates Taken From the Original Armour in the Tower of London, and Other Arsenals, Museums, and Cabinets
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A Sketch of the Life and Writings of Robert Knox, the Anatomist
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Horse-Hoeing Husbandry
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Sir Morell Mackenzie; Physician and Operator
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Passages From the Diary of a Late Physician; Volume 1
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The Resilient Clinician
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Hearing Disorders
This book focuses on research on sensorineural hearing loss, syndromic or non-syndromic, related to genetic and viral factors. The metabolic syndrome, autoimmune etiopathogenesis, and new elements of cochlear implantation were also evaluated. New developments and utility of laboratory tests in inner ear diseases (sudden sensorineural hearing loss, Meniere disease, benign paroxysmal positional vertigo, vestibular neuritis) are also discussed.
New Trends in Cognitive Ageing and Mild Cognitive Impairment
This book focuses on the process of cognitive ageing, considering the increase in cognitive impairment associated with the aging of the population and the related care impact.Special attention is given to cognitive health changes linked to the increase in life expectancy, including the role of subjective factors; the link between cognitive function, mobility and functionality; and the potential role of digital technologies, including computerized cognitive tests and virtual reality environments.
Advanced Materials for Oral Application
This book consists of one editorial, 12 original research articles and two review papers from scientists across the world, with expertise in materials for dental application. The main subjects covered are: biomaterials and techniques for oral tissue engineering and regeneration; biomaterials for surgical reconstruction; CAD/CAM technologies and dedicated materials; novel restorative and endodontic materials and instruments.
The Surgical Clinics of North America, Volume 1, issue 2
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Diagnostic Genetic Testing
Over the last decade, technical advances have allowed genomic testing which provides a great opportunity for diagnosis but also an increased chance of uncertain or unexpected findings. This book addresses many of the questions that arise in this context and summarizes the essential concepts in diagnostic genetic testing in an easy-to-read manner. It also covers some broad context for the practical and ethical implications of examining human DNA sequences. The book starts with a general introduction to the field, providing enough background to allow readers without any previous education in genetics to comprehend the material in the subsequent chapters. The main part explores differing aspects of human genetics and the wider implications of testing in these areas. The author covers not only single gene inheritance, but also genetic testing of cancers and how testing benefits the patients. Special emphasis is also given to the questions of genetics and identity. The concluding part then draws the main themes together and summarises the wider significance of genetics. It also explores the gap between promises made for the impact of advances in genetics, and the actual benefits to patients. The book is written for everyone interested to learn about the process of genetic testing and the broader implications. Moreover, it is aimed at health professionals with an interest in genetics, at students or scientific trainees looking for an introduction to diagnostic genetics, and at professionals in health policy or health journalism.
Memoirs and Letters of Sir James Paget
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The Universal Cook, and City and Country Housekeeper
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Epilepsy and its Cure
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Manual for the Medical Department
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Current Research on HIV Drug Resistance
HIV drug resistance is an unavoidable challenge for HIV/AIDS professionals, and it has long been a major obstacle hindering the global effort to contain HIV/AIDS. Pathogens journal launched a topical collection in 2021 on "Current Research on HIV Drug Resistance", aiming to catch the latest advancements in HIV resistance diagnosis, surveillance and research. This book compiles all articles published in this collection, combining original research and review articles on HIV drug resistance.
A Plain and Familiar Method for Attaining the Knowledge and Practice of Common Arithmetic. Containing All the Useful Rules Both in Whole Numbers, and Fractions, Vulgar and Decimal, Extraction of the S
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Memoirs and Letters of Sir James Paget
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The Hygiene, Diseases and Mortality of Occupations
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Principles of Military Movements, Chiefly Applied to Infantry
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Mr. Putter & Tabby Ring the Bell
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The Science of Oriental Medicine
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The Universal Cook, and City and Country Housekeeper
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Handbuch Der Fleischkunde
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