Handbook of Medicinal Plants of the World for Aging
This book discusses the various medicinal plants and food plants used around the world that contribute to their people living longer and healthier lives. The text covers the physiological process of ageing from the molecular and cellular to organ levels, and also looks into skin and hair age-related effects of ageing.
Molecular Recognition in Pharmacology
This unique volume gives the basics of thermodynamics and kinetics of complex formation between ligands and receptors. The book is intended for pharmacologists, chemists, physics engaged in the creation of new medicinal substances.
Regulatory Aspects of Pharmaceutical Quality System
If you're a B. Pharm or M. Pharm student seeking a comprehensive yet concise guide to the regulatory aspects of pharmaceutical quality systems, look no further than Regulatory Aspects of Pharmaceutical Quality System - Brief Introduction. While other textbooks on quality assurance cover a variety of topics to varying degrees of depth, this book provides a unified approach that is both insightful and practical. Designed to meet the needs of modern students and instructors, this book covers the basic guidelines and principles of quality assurance as they relate specifically to drug design, development, and evaluation. You'll learn about the latest developments in the industry and how to apply these principles to the real-world challenges that you're likely to encounter. Whether you're a seasoned pharmaceutical professional or just starting out, you'll find this book to be an invaluable resource that you'll refer to time and time again.
MCQs in Pharmacology and Toxicology
"MCQs in Pharmacology and Toxicology" offers a deep dive into the world of pharmacology, providing an analysis and study of the subject based on many reputed books and paragraphs. The result is a vast collection of multiple-choice questions that cover important concepts and theories within pharmacology and toxicology. The book is designed to provide students with a systematic approach to studying the subject matter, and it encourages readers to follow the "MCQs in Pharmacology and Toxicology" book as a foundational resource. Additionally, all of the questions in the book align with theory lectures that are offered by Solution Pharmacy, India's top YouTube channel for pharmacy-related study materials. One of the unique features of this book is that it is designed in a partwise pattern that helps students develop a deep understanding of the subject matter. It also includes a comprehensive answer key with correct options and option names located at the end of each question set. Finally, students can take advantage of the offline and online MCQs available in the Solution Pharmacy mobile application. Whether you're prepping for a licensing exam or simply want to deepen your knowledge of pharmacology and toxicology. "MCQs in Pharmacology and Toxicology" is an essential resource for mastering pharmacology.
Emergency Medicine Thinker
'Emergency Medicine Thinker' is a practical pocketbook that provides important considerations for the practice of emergency medicine. Based on the popular website created by the authors, 'emDocs.net', it covers practical thinking rules that can be applied on an emergency medicine shift and provides approaches to common and life-threatening diseases in the ED that physicians see on a regular basis. Easy to read with quick access to information, and full of essential tips and pearls from experts on the emergency frontlines, this is a handbook that can be used at the bedside on shift. Part 1 of the book explores the EM decision-making process and why it's important from a myriad of central and talented emergency physicians. Part 2 features over 170 pearls for the frontline EM clinician. This book is a must-have for anyone working in emergency medicine.
Pharmacovigilance
Written by multidisciplinary experts in the fields of pharmaceutical and patient safety, Pharmacovigilance: A Practical Approach, Second Edition, provides a succinct, easy-to-digest overview of an increasingly critical area of medical safety. From cover to cover, this concise resource offers essential information for physicians and other health care professionals, clinical researchers, and regulators who need a comprehensive, up-to-date source of information on the principles and practice of pharmacovigilance.Presents vital, easy-to-read, cutting-edge information on patient safety, the pharmacology regulatory landscape, and the current and future use of digital technologiesProvides up-to-date coverage of hot topics in the field, including pharmacodynamic and safety precision medicine, immunogenicity, vaccine hesitancy and safety, genetic toxicology, and adverse eventsContains new chapters on pre-clinical safety assessment, pharmacogenetics, first-in human trials, product aggregate safety assessment, data monitoring committees, and moreOffers new and expanded coverage of pharmacovigilance in early pre-clinical drug development through post-marketing surveillance, as well as a blueprint for training future pharmacovigilance professionalsIncludes real-world case studies to ensure content is relevant and applicable to everyday practiceDiscusses a range of topics across disciplines and how they relate to pharmacovigilance, including behavioral science, patient perspectives, and risk communicationAn eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Prevention, Diagnosis and Treatments of Early-Stage NSCLC
The following Special Issue on the "Prevention, Diagnosis and Treatments of Early-Stage NSCLC: New Advances and Future Prospective" forms a collection of articles showcasing the latest scientific progress in this field, focusing particular attention on minimally invasive techniques such as video-assisted thoracic surgery (VATS) and robotic-assisted thoracic surgery (RATS) compared to open surgery both for early and long-term outcomes in addition to the role of sublobar resection for the treatment of early-stage NSCLC compared to lobectomy. Moreover, we also focus on the importance of recently identified potential biomarkers such as TLR expression to be used for future prognostic purposes in NSCLC and the importance of enhancing immune response in NSCLC patients with the use of the 13-valent pneumococcal conjugate vaccine (PCV13).
The anatomy of drunkenness
Unlock the Secrets of the Past with a Timeless Classic! Dive into the fascinating world of ""The Anatomy of Drunkenness"" by Robert Macnish, a captivating exploration of the human condition and its age-old relationship with alcohol. First published in the 19th century and out of print for decades, this remarkable work has been lovingly republished by Alpha Editions for the current and future generations. Macnish's insightful and often humorous examination of intoxication, its effects, and its cultural significance offers readers a unique glimpse into the past while remaining strikingly relevant today. Whether you're a history enthusiast, a psychology buff, or simply curious about the quirks of human behavior, this book is a must-have addition to your collection. More than just a book, this is a collector's edition-a rare gem that promises to enlighten, entertain, and provoke thought. Don't miss your chance to own a piece of literary history that continues to resonate through the ages. Grab your copy now and embark on a journey through the intoxicating pages of ""The Anatomy of Drunkenness""!
Chronicles of Pharmacy, Vol. 2
Discover the Fascinating World of Pharmacy Through the Ages! Step into the captivating realm of ""Chronicles of Pharmacy, Vol. 2"" by A. C. Wootton, a timeless treasure that has been out of print for decades and is now beautifully republished by Alpha Editions for the curious minds of today and tomorrow. This collector's edition is not just a book; it's a journey through the rich legacy of pharmaceutical history, unraveling the secrets and stories behind the evolution of medicine. From ancient potions to groundbreaking discoveries, Wootton's masterful narrative brings to life the pivotal moments and remarkable figures that have shaped the world of pharmacy. Whether you're a history enthusiast, a medical professional, or simply someone with a thirst for knowledge, this book offers a unique glimpse into the past, illuminating the path to modern medicine. Don't miss your chance to own a piece of history. Dive into ""Chronicles of Pharmacy, Vol. 2"" and let the adventure begin!
Chronicles of Pharmacy, Vol. 1
Discover the Fascinating World of Pharmacy Through the Ages! Step into the captivating realm of ""Chronicles of Pharmacy, Vol. 1"" by A. C. Wootton, a timeless masterpiece that unveils the rich legacy of pharmaceutical history. This extraordinary volume, out of print for decades, has been lovingly republished by Alpha Editions for the curious minds of today and tomorrow. Journey through the ages as Wootton masterfully chronicles the evolution of pharmacy, from ancient potions and elixirs to the groundbreaking discoveries that shaped modern medicine. With engaging narratives and intriguing anecdotes, this collector's edition is not just a book-it's a treasure trove of knowledge and a testament to human ingenuity. Whether you're a history enthusiast, a medical professional, or simply curious about the roots of the remedies we rely on today, ""Chronicles of Pharmacy, Vol. 1"" promises to enlighten and inspire. Don't miss your chance to own a piece of history-secure your copy now and embark on an unforgettable journey through the chronicles of pharmacy!
Case of Filaria loa
Unlock the Mysteries of a Medical Marvel: ""Case of Filaria loa"" by Douglas Argyll Robertson Dive into the captivating world of medical discovery with ""Case of Filaria loa,"" a groundbreaking work by the esteemed Douglas Argyll Robertson. This fascinating exploration of the Filaria loa parasite, a rare and intriguing nematode, offers readers a unique glimpse into the challenges and triumphs of 19th-century medical science. Once lost to the sands of time, this extraordinary book has been out of print for decades. Now, thanks to the dedicated efforts of Alpha Editions, it has been lovingly republished for the current and future generations. This is not just a book; it's a collector's edition-a treasure trove for enthusiasts of medical history and curious minds alike. With its compelling narrative and insightful observations, ""Case of Filaria loa"" invites you to journey alongside Robertson as he unravels the mysteries of this elusive parasite. Whether you're a medical professional, a history buff, or simply a lover of intriguing tales, this book promises to enlighten and inspire. Don't miss your chance to own a piece of medical history. Add this rare gem to your collection today and discover why ""Case of Filaria loa"" continues to captivate readers over a century later.
Updates on Caries Management in the Primary and Permanent Dentition
The aim of the following reprint is to provide the reader with the latest updates on caries management in primary and permanent dentition. This Special Issue contains articles presenting innovative approaches, high-quality clinical, epidemiological, and dental public health research, and translational research in the field of caries management. Focuses include aspects of preventive, non-invasive, minimally invasive, and operative dentistry in children and adults. Primarily, clinical trials are looking, for example, at the use of silver (diamine) fluoride. Interestingly, this product seems to be experiencing a renaissance, leading to an expanded treatment spectrum, especially in pediatric dentistry. Alternatively, non-clinical study types demonstrate the facets of current research in cariology that aim to produce a large body of evidence, such as systematic reviews, or focus on possible clinical implications, such as decision-making in caries management. As a result, readers with both scientific and clinical backgrounds can gain important recent insights into various aspects of cariology from this reprint.
Advances in Diagnosis and Management of Pancreatobiliary Disorders
In recent years, the management of many diseases of the biliary tract and pancreas has undergone great changes due to the rapid progression of diagnostic and therapeutic technologies. For biliary diseases, the constant technological evolution of endoscopic methods such as EUS, ERCP, and cholangioscopy has changed the diagnostic and therapeutic approach and management of many common pathologies, such as biliary lithiasis and its complications. Pancreatology is also constantly evolving, both from a clinical and diagnostic-instrumental point of view, such as in the approach to solid and cystic lesions of the pancreas, due to the increasingly routine use of EUS, both diagnostic and therapeutic, and the new knowledge regarding rarer neoplasms such as neuroendocrine tumors. Beyond that, new technologies based on artificial intelligence are beginning to make their way into gastroenterology. The evaluation of patients with biliopancreatic pathology is becoming increasingly complex and challenging. This reprint presents the latest innovations in the management of pancreatic and biliary tract diseases with the goal of providing the Internal Medicine physician with a state-of-the-art update and insights into the most current innovations.
Advances in Glaucoma Management and Intraocular Pressure Physiology
"Advances in Glaucoma Management and Intraocular Pressure Physiology" brings together a comprehensive collection of cutting-edge research on glaucoma, emphasizing both clinical and translational innovations. This reprint highlights innovative clinical and translational studies on aqueous outflow physiology, intraocular pressure measurement, and glaucoma management. Further, it explores groundbreaking developments in pressure-independent neuroprotection, dynamic intraocular pressure monitoring, and ocular biomechanics, which offer insights into glaucoma progression and management. The collection encompasses diverse topics, including the efficacy of novel therapeutics like Rho-kinase inhibitors, the evolving role of minimally invasive glaucoma surgery (MIGS), and advancements in imaging and diagnostic techniques. Key studies investigate retinal ganglion cell function post treatment, 24- and 48-hour intraocular pressure profiles, and the implications of anti-VEGF therapy in glaucoma management. Other contributions address unique challenges in uveitic and pediatric glaucoma while exploring new surgical and medical targets. This reprint serves as an essential resource for clinicians, researchers, and specialists aiming to deepen their understanding of glaucoma's complexities and enhance therapeutic approaches to this sight-threatening disease.
Recent Advances of Avian Viruses Research
This Special Issue includes all research aspects of avian virus research, including the molecular virology, viral immunology, viral pathogenesis, epidemiology, antivirals, novel vaccines, and applications of avian viral vectors, established by various international expert research groups, in order to advance the global understanding of avian pathogens. This Special Issue provides an exceptional example that will lead to more excellent studies in the future.
Clinical Management of Patients with Heart Failure
This reprint comprises chapters describing new diagnostic approaches, risk assessment strategies, challenges encountered in peculiar patients, innovative drug therapies, and invasive procedural options. It starts by pointing out the prognostic value of several biomarkers for diagnosis, risk stratification, and follow-up of patients with heart failure. Another aspect is the significance of genetic mutations in patients with life-threatening arrhythmias. Other points of interest in this reprint concern a more accurate evaluation of left ventricular systolic function that involves non-invasive methods (transthoracic echocardiography and electrocardiography Holter monitoring). Then, this reprint continues by highlighting the important contribution of various cardiovascular complications and comorbidities severely impacting the outcome of patients with heart failure. Another section of this reprint is dedicated to the therapy of chronic heart failure, starting with the importance of non-pharmacological methods and identifying patients with difficulties in their self-management that have resulted in compliance issues. Regarding therapy, special emphasis is given first to optimizing medication and, on the other hand, to employing left ventricular assistance devices, where necessary, or mechanical cardiocirculatory support as a bridge preceding cardiac transplantation. Finally, a special matter of concern is the treatment of acute heart failure where therapeutic strategies are less standardized.
Fundamentals of Anthroposophical Medicine
4 lectures, Stuttgart, October 26-28, 1922 (CW 314)"I think the stimulus given by anthroposophic research to medicine and to natural-scientific thinking ought to be worked out by those who are specialists in the various domains. Indeed, all that comes from anthroposophic investigation regarding medicine and, for instance, physiology, can be no more than a stimulus that must then be worked out empirically. Only on the basis of this empirical study can there arise valid and convincing judgments of the matters in question--and this is the kind of judgment that is needed in the domain of therapy." -- Rudolf Steiner (Oct. 26, 1922)What is the difference between natural science and spiritual science? Dr. Steiner illumines this question and others in these fundamental lectures for understanding of the anthroposophic approach to human illnesses and their treatments.Topics discussed include the structure of the brain; breathing, metabolic, anabolic, and catabolic processes; the human threefold organization and growth forces; the earth, water, air, and fire elements of the human organism.This volume contains four lectures translated from the German text Physiologisch- Therapeutisches auf Grundlage der Geisteswissenschaft (GA 314).
The Washington Manual Endocrinology Subspecialty Consult
Concise, portable, and user-friendly, The Washington Manual(R) Endocrinology Subspecialty Consult, 5th Edition, provides quick access to the essential information needed to evaluate a patient on an endocrinology subspecialty consult service or in the outpatient setting. Edited by Drs. Janet B. McGill, Julie M. Silverstein, and Sina Jasim, this bestselling manual offers state-of-the-art guidance on the history, physical exam, diagnosis, management, and follow-up for various endocrine and metabolic disorders. Ideal for residents cycling through an internal medicine subspecialty clinical rotation or for fellows who need to better understand the fundamentals, the manual is also useful as a first-line resource for internists and other primary care providers. Enables on-the-spot bedside patient diagnosis and management with quick, efficient answers to your fundamental questions about diagnosing and treating endocrine and metabolic disorders Thoroughly revised to include a greater emphasis on treatment and therapies, including coverage of new drugs and expanded content on transgender medicine and diabetes devices Uses a consistent format throughout and outlines symptoms, signs, and problems in bulleted lists for easy, everyday reference Written by specialty fellows and faculty in the Department of Medicine at Washington University School of Medicine in St. Louis The Washington Manual(R) is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by Wolters Kluwer Health under license from Washington University.
Surface and Interface Modification of Graphite and Graphene-Based Materials for Energy and Sensor Applications
Surface and Interface Modification of Graphite and Graphene-Based Materials for Energy and Sensor Applications delves into the latest advancements in carbon-based materials, focusing on how their surface and interface modifications enhance performance in critical applications. This comprehensive collection covers topics such as energy storage, fuel cells, hydrogen storage, biosensors, and environmental monitoring devices. Featuring cutting-edge research on the synthesis and functionalization of graphite and graphene composites, the Special Issue highlights the importance of optimizing these materials for use in supercapacitors, gas sensors, liquid sensors, and more.Written by leading experts in the field, this Reprint serves as an essential reference for researchers, engineers, and professionals working in materials science, nanotechnology, and renewable energy. It is particularly relevant for those seeking to harness the unique properties of graphite and graphene for innovative solutions in energy and sensing technologies. Whether you are developing next-generation batteries or creating ultra-sensitive biosensors, this volume offers valuable insights into the future of carbon-based materials.
Formulation and Optimization of Lamivudine Microspheres
The main objective of the present work was to develop a formulation with increased therapeutic efficacy, reduced frequency of administration and improved patient compliance by developing sustained release microspheres of Lamivudine using different polymers to study its functionality for sustained release of drug from microspheres formulations. Different concentrations of polymers like sodium alginate, HPMC, sodium CMC, chitosan was selected for the study. Microspheres were prepared by using ionic- gelation method. Prepared microspheres were evaluated for particle size, flow properties, drug content, entrapment efficiency. After evaluation of physical properties of microspheres, the in vitro release study was performed in 0.1 N HCl as buffer for 2 hrs. after that replace with 6.8 phosphate buffer up to 8hrs. After 8 hrs. of study microspheres with sodium CMC showed maximum release (88.2%). Among all the formulations F7 which contain 200 mg of sodium CMC release the drug which follows first order kinetics. The optimized formulation of sodium CMC (F7) was subjected to stability with respect to release pattern.
From Molecules to Materials, Devices and Processes
This Special Issue was launched in connection with the joint XIII National Congress of AICIng (the Italian Association of Chemistry for Engineering) and the II National Congress of the Division of Chemistry for the Technologies of the Italian Chemical Society, held at the Politecnico di Milano (Italy) from 25 to 28 June 2023. The aim of the Congress was to present and discuss recent advances in fundamental and applied chemistry in the fields of new or improved technologies, comprising compounds, materials, or processes. In this Special Issue, we pointed out that chemistry provides a molecular-level tool, allowing for significant advances in current and novel technologies in a wide range of fields. In this Special Issue, we collected selected relevant examples of the chemical foundations of the technologies that produced the new, scientific, and technologically innovative results obtained in Italy and elsewhere, in which various methodologies and approaches were used to design new products, materials, or processes in a wide range of fields.
Aggregatibacter actinomycetemcomitans
This reprint is devoted to the oral microbe Aggregatibacter actinomycetemcomitans and its associated distinctive form of rapidly destructive periodontitis that results in early tooth loss, predominantly occurring in adolescents and children of African descent. Three chapters are related to the biological and clinical characteristics of the disease, while six chapters are devoted genetic features uniquely suited for local disruption of the host's homeostatic balance. The final two chapters illustrate how a deep molecular understanding of A. actinomycetemcomitans has been used to develop therapies for diseases such as staphylococcal infections and leukemias. The reprint illustrates A. actinomycetemcomitans's 1) highly adaptable nature, 2) its influence on its microbial cohorts, 3) its modulation of local host responsiveness, and 4) its relationship to tissue damage, microbial survival tactics, and metabolic and competitive ecological strategies. These microbe-related processes can be applied to other infectious diseases. The Damage-Response Framework is illustrated as the most appropriate way to consider this microbe, its effect on its host, and the relationship of time to the extent of damage or repair.
Photocatalytic Materials and Photocatalytic Reactions
Photocatalysis is a chemical process that utilizes light energy to accelerate thermodynamically demanding reactions. It offers a sustainable and eco-friendly solution for energy production and environmental remediation. With the increasing demand for clean energy and the need to mitigate environmental pollution, photocatalytic research has gained significant momentum. In recent years, photocatalysis has been rapidly developed, and numerous new photocatalysts and photocatalytic reactions have been explored. However, designing advanced photocatalysts, understanding their structure-dependent properties, and seeking new photocatalytic reactions remain prominent challenges. Herein, various photocatalytic materials, including metal oxides, metal sulfides, metal nitrides, metallo-organic compounds, g-C3N4, clusters, LSPR, magnetic materials and heterojunction/composite materials, etc., are introduced. The photocatalytic applications in hydrogen production, carbon dioxide reduction, organic synthesis, environmental remediation, disinfection, toxicity, and dual-function photoredox reactions are also studied. We hope that these works can inspire other researchers and lead to new developments and breakthroughs in the field of photocatalysis.
Valvular Heart Disease
Calcified aortic valve disease (CAVD) affects over six million Americans and is associated with changes in the mechanical properties of valve leaflets, resulting in impaired valvular blood flow. CAVD is a fibrocalcific disease with multifactorial risk factors that are related to the complex environment where the aortic valve (AV) resides. This special issue focuses on the field of heart disease, exploring the relationship between heart valve disease, arrhythmia, kidney disease, and cardiovascular disease, as well as research progress on new treatment strategies and risk prediction.
Updates on Imaging of Common Urogenital Neoplasms
Urogenital neoplasms represent some of the most common malignancies. Advances in imaging have proved vital in early cancer detection and accurate tumor staging, as well as adequate treatment planning, monitoring of the disease, and enhanced surveillance of recurrences after treatment in patients with genitourinary cancers. The aim of this Reprint is to present the role of current imaging techniques, including ultrasonography, computed tomography, magnetic resonance imaging, and fluorodeoxyglucose-positron emission computed tomography, in the follow-up of patients with urogenital neoplasms. The potential applications of novel imaging tools are also discussed. This Reprint contains 10 articles and deals with gynecologic malignancies, testicular tumors, renal masses, and urothelial neoplasms.
Rheumatoid Arthritis
In the last 25 years we have witnessed a change in the approach to rheumatoid arthritis. These changes have made it possible to modify the clinical course and prognosis of the disease, with the subsequent improvement in the quality of life of our patients. This Special Issue explores the most important changes that have occurred in recent years. It starts with an excellent point of view on preclinical arthritis and how we must treat it, considering the window of therapeutic opportunity. Next, because the RA is a condition that predominantly affects women, we discuss the disease through the lens of gender, empathizing the need for this perspective to achieve better research results and personalized medicine. Regarding treatment, the issue takes a journey that begins with the necessity of changing the old paradigm of treatment and the necessity of advancing DMARD lines. We then continue with the anchor drug, methotrexate, and its toxicity then advancing with the real-world persistence of Janus kinase inhibitors, sex differences in response to JAKi and infections related to these drugs. Finally, we examine comorbidities, starting with the Interstitial lung disease, Neutropenia and Felty syndrome and the relevance of radiographic progression. I hope that the issue can be useful for clinicians, rheumatologists, internal medicine specialists, primary care physicians, hematologists, pneumologists, etc. involved in the care of rheumatoid arthritis patients.
Nutrition Interventions for Healthy Ageing
Ageing is associated with several factors potentially affecting nutritional status. These may be environmental (lack of resources, feelings of loneliness or social isolation, etc.) or biomedical (loss of appetite, taste, or smell, slower metabolism, decreased sense of thirst, pain in teeth and gums, etc.). This exposes older adults to numerous potential complications such as cardiovascular problems, phosphocalcium metabolism disorders, sarcopenia, functional dependence, and death. The challenge for specialists in the field of ageing is, therefore, to manage and ideally prevent these nutritional disorders to promote successful ageing. This Reprint collects research on epidemiological, clinical, and biological aspects of nutrition and the impacts of nutritional interventions in older adults.
Clinical and Ethical Dilemmas in Palliative and End-Of-Life Care
Part of the "What Do I Do Now: Palliative Care" series, Clinical and Ethical Dilemmas in Palliative and End-of-Life Care bridges the gap between the clear, logical, and harmonious clinical world of textbooks and the chaotic, turbulent, resource-constrained, and often unpredictable world of everyday practice. Each chapter begins with a case and is followed by a diagnosis, explanation of next steps, and rationale for decision-making by experts in the field, mimicking the kind of "curbside consult" that occurs between an experienced clinician and someone new to the field. Tackling dilemmas related to patients, families, healthcare professionals, and the healthcare system, this book comprehensively helps readers learn to apply practical knowledge in challenging circumstances-and often with incomplete information-to achieve clinical competency. The volume is also a self-assessment tool that tests the reader's ability to answer the question, "What do I do now?"
