Study of Refractory COD Removal from Pharmaceutical Wastewater
This study investigates the treatment of pharmaceutical wastewater containing recalcitrant, non-biodegradable compounds that are inadequately addressed by conventional treatment methods. The objectives include improving wastewater biodegradability and comparing the efficacy of various advanced treatment approaches. Untreated wastewater samples were collected from a pharmaceutical intermediate manufacturing unit. Initial characterization, including pH measurement and acute toxicity assessment, was conducted. Primary treatment involved neutralization, coagulation, flocculation, and settling. Advanced oxidation processes (AOPs) such as H₂O₂, TiO₂/H₂O₂, Fe簡⁺/H₂O₂ (Fenton), HCO₃⁻, and Fe簡⁺/H₂O₂/O₃ (Fentozone) were applied.Post-treatment analyses revealed varied improvements in biodegradability (BOD/COD ratio). The Fentozone process emerged as the most effective, achieving a BOD/COD improvement of 0.43 after 60 minutes. Comparative results showed moderate improvements with TiO₂/H₂O₂ (0.32) and Fe簡⁺/H₂O₂ (0.30), while H₂O₂ alone achieved a marginal improvement of 0.26. No improvement was observed with HCO₃⁻treatment.In conclusion, the Fentozone process proves to be a promising technology.
Method Development and Validation for Voriconazole Estimation
A rapid, sensitive, and specific RP-HPLC method with UV detection was developed and validated for the determination of voriconazole. Chromatography was performed on an Enable C18 G column (250 ? 4.6 mm) in isocratic mode, using a mobile phase of methanol and acetonitrile (60:40, v/v). The flow rate was set at 1 mL/min, and the effluent was monitored at 223 nm. Chromatographic analysis revealed a main peak for voriconazole at a retention time of 2.841 minutes. Methanol was selected as the solvent for the analysis, with the λmax determined to be 223 nm. The method exhibited linearity over a concentration range of 5-30 繕g/mL. Validation parameters, including linearity, range, precision, accuracy, limit of detection (LOD), and limit of quantitation (LOQ), were assessed and met the required standards.
Synthetic Organic Chemistry and the Nobel Prize, Volume 3
The Nobel Prize is the highest award in science, as is the case with nonscience fields too, and it is, therefore, arguably the most internationally recognized award in the world. This unique set of volumes focuses on summarizing the Nobel Prize within organic chemistry, as well as the specializations within this specialty.
Fundamentals of Gastroretentive Drug Delivery Systems
This book provides basic concepts related to gastroretentive drug delivery systems This book covers the aspects of anatomy & physiology of the GIT, approaches for gastric retention. This book also emphasizes on formulation aspects with detailed information and the evaluation aspects including the in vitro and in vivo parameters, applications and the research work done on gastroretentive systems This book will serve for under graduate students.
Biological Activities and Potential Applications of Phytotoxins
This reprint focuses on the isolation and characterization of some phytotoxins and the evaluation of their biological activities for potential application in different fields. Plants and microbes are able to produce several specialized (secondary) metabolites belonging to different classes of natural compounds. Among them, phytotoxins are substances that are poisonous or toxic to plants. They seem to play an important role in plant-pathogen interactions when produced by phytopathogenic fungi or bacteria, while plant-produced phytotoxins-including allelochemicals-seem to be involved in plant-plant interactions. Thus, the determination of their chemical structure and their identification are fundamental for chemical ecology and for understanding their function. However, most of these compounds have already shown other interesting biological activities and potential applications in fields such as agriculture or medicine. In fact, some phytotoxins have already been proposed for the development of biopesticides, cosmetics, and drugs.
Gastroretentive Floating Drug Delivery System of Zaleplon Tablets
Floating Drug Delivery Systems are retained in the stomach for a longer time and assist in improving the oral controlled delivery of drugs that have an absorption window in the particular region of the GI tract as well as for controlling the release of the drug having site-specific absorption limitationZaleplon is a highly effective sedative-hypnotic that was used as a model drug to develop a controlled-release formulation. Zaleplon exhibits pH-dependent solubility. It is more soluble in acidic pH and slightly soluble in neutral or alkaline conditions (intestinal environment). Hence an attempt was made to develop a gastroretentive delivery system Zaleplon which increased the bioavailability of Zaleplon and also reduced the frequency of administration, thereby improving patient compliance and therapeutic efficacy.
Anti-Retroviral Therapy (ART) in HIV/AIDS patients
It was found that patients receiving ZLN show significant increase in levels of Triglycerides, Indirect Bilirubin serum creatinine and shows slight increase in levels of Total Bilirubin, and SGPT and show significant decrease in HB levels. Patients receiving TLE drug combination shows significant increase in levels of SGPT, Indirect Bilirubin, serum creatinine and shows slight increase in levels of Total cholesterol, CD4 count and slight decrease in levels of RBC, VLDL. So, the systems that were mostly affected due to ART therapy were found to be hepatic and renal systems along with significant alterations in the lipid profile. In order to slow down the deterioration process, drug use must be optimized along with the periodic monitoring of the systems.
Development of Clotrimazole Emulgel
Clotrimazole is an imidazole derivative with a broad spectrum of anti-mycotic activity. The Present investigation is the design and characterization of Novel Emulgel of Clotrimazole. Nine different formulations of Emulgel were prepared by the proposed method of preparation by Mohammad et.al (2004), varying with different 2 different polymers of gelling agent such as Carbopol 934 and HPMC K15 M and their combinations in different ratios. All the Formulations were characterized for physical evaluation, drug content, Viscosity, spreadability, extrudability, and In-vitro Drug release studies. Stability studies were revealed with marginal differenceswith a good stability. Also this study refers to the kinetic data of the drug release studies.
Salbutamol Drug Delivery by Core in Cup Device
Core and cup tablet of Salbutamol sulphate for chronotherapeutic delivery was prepared to increase the effectiveness of drug by using optimization technique.The formulation contains three components a core tablet, impermeable layer and soluble hydrophilic polymer layer. The core tablet contains salbutamol sulphate drug and other excipients, impermeable layer is made up of Ethyl cellulose (EC), and the polymer layer is made of HPMC 15cps and HPMC 50cps. In this work the key ingredients like HPMC 15cps and HPMC 50cps were optimized by using 32 Factorial designing in this various proportions of HPMC 15cps and HPMC 50cps (polymers) were used in different levels in the preparation of core in cup tablet.
Clinical Pharmacy Practice
This book equips students with foundational knowledge and practical skills necessary for pharmacy practice, focusing on delivering pharmaceutical care in clinical settings. Upon completion, students are expected to understand and provide comprehensive patient care, interpret laboratory results to support clinical diagnoses, and offer well-analyzed medicine and poison information to healthcare professionals for effective patient management.
Antifungal therapy in the hematologic patient
Fungal diseases are a type of disease associated with a patient undergoing hematopoietic stem cell transplantation (HSCT). HSCT is a therapy to replace a damaged hematopoietic system with a healthy one from a donor. Hematopoietic stem cells are those capable of regenerating all cell types of blood cells.The aim of this review is to know the hematologic transplant patient and the characteristics that predispose him/her to suffer invasive fungal infections, as well as to know the methods of prophylaxis and treatment and to describe the most commonly used antifungal drugs.
Orally Disintegrating Tablets of Amlodipine Besylate
In the present study, orally disintegrating tablets (ODTs) of amlodipine besylate was prepared by using two types of natural super disintegrants in different ratios by direct compression method. The basic approach followed in this study was to achieve rapid disintegration. The evaluation of ODTs of amlodipine was performed for general appearance, physical parameters such as hardness, friability, wetting time, weight variation, uniformity of drug content, in vitro disintegration, in vitro dissolution studies. The above-mentioned tests were performed using the official procedures and with modified testing procedures collected from various research articles. Further the ODT formulations were subjected to further evaluation testing.
Scorpion Venom
This book comprehensively examines scorpion biology, discussing their taxonomy, anatomy, and the complex nature of their venom. It delves into the medical implications of scorpion venom, including its role in treating diseases. This book is intended for researchers, clinicians, and students of toxicology, pharmacology, and arachnology.
Toxic Sexual Politics
A bold expos矇 of how the very foundation of toxicology has been contaminated by sexist and racist ideologies The first critical understanding of the field of toxicology from a feminist and antiracist perspective, Toxic Sexual Politics asserts that the science of toxicants must be held accountable for the uneven distribution of toxic pollution along racial and sexual lines. Drawing upon in-depth interviews and extensive ethnographic and archival research, including participant observations in toxicology classrooms, conferences, and laboratories, Melina Packer urges environmental health advocates to place toxicant science within its masculinist, militarist, and eugenicist history. Toxic Sexual Politics shows how the founding fathers of U.S. toxicology were ideologically aligned with the chemical industry, inventing a science that could "make chemicals safe," as opposed to one that could adequately protect planetary health from toxicants' hazards. While many toxicologists today are critical of the chemical industry, they continue to rely on the highly limited tools of toxicology as accurate measures of toxicity, as do government regulators, the courts, and environmental advocates. Unlike most critiques of the chemical industry and narratives of environmental health movements, Toxic Sexual Politics refuses to take the science at face value. By focusing on the sexist, racist, and ableist biases reinforced by toxicology, Packer powerfully argues that this scientific discipline reproduces the very same white supremacist and heterosexist logics that generated environmental injustices in the first place. The field of toxicology can explicitly confront chemical corporate power by building from queer, feminist, anti-ableist, and antiracist movements for environmental and reproductive justice.
My Leper Friends
NEW PRINT WITH PROFESSIONAL TYPE-SET IN CONTRAST TO SCANNED PRINTS OFFERED BY OTHERS My Leper Friends: An Account Of Personal Work Among Lepers, And Of Their Daily Life In India With A Chapter On Leprosy, By Surgeon-Major G. G. Maclaren, M.D. This book is a result of an effort made by us towards making a contribution to the preservation and repair of original classic literature. In an attempt to preserve, improve and recreate the original content, we have worked towards: 1. Type-setting & Reformatting: The complete work has been re-designed via professional layout, formatting and type-setting tools to re-create the same edition with rich typography, graphics, high quality images, and table elements, giving our readers the feel of holding a fresh and newly reprinted and/or revised edition, as opposed to other scanned & printed (Optical Character Recognition - OCR) reproductions. 2. Correction of imperfections: As the work was re-created from the scratch, therefore, it was vetted to rectify certain conventional norms with regard to typographical mistakes, hyphenations, punctuations, blurred images, missing content/pages, and/or other related subject matters, upon our consideration. Every attempt was made to rectify the imperfections related to omitted constructs in the original edition via other references. However, a few of such imperfections which could not be rectified due to intentional\unintentional omission of content in the original edition, were inherited and preserved from the original work to maintain the authenticity and construct, relevant to the work.
Phytochemical Screening & Activity of M.sapientum & P.dactylifera Leaf
The plants, Musa sapientum and Phoenix dactylifera, have been selected on the basis of its presence in Ayurveda as well as having its many traditional uses whereas not properly and scientifically explored or reported so far. Traditionally, the plants are used against diarrhea, diabetes and menorrhagia, otalgia, haemoptysis and also used as an anthelmintic etc. Impetuses have been given on the leaves of those plants for the benefits of researchers and manufacturers of formulations made from it. Further future work may be done on the leaves of those plants on other aspects, our findings say so. The anti-ulcer activity was studied and found to be new compounds (from the point of scientific evaluation) have been reported first time even though the plants (Musa sapientum and Phoenix dactylifera). Isolation and structure elucidation of certain compounds from the leaves of those plants have been done successfully, in two of the cases at least. Present work has covered all the above aspects, which have been presented in 10 chapters in a logical sequence with relevant references annexed to each chapter. In the conclusion, all the observations and findings have been placed.
The effect of COVID-19 on Mental Health
The Corona virus Disease 2019 (COVID-19) is a pandemic that emerged for the first time in Wuhan, China, and spreads all over the world between December 2019 and early 2020. The state of lock-down in many parts of the world, which are contributing largely to the global economy has led to the halting of services and products. Along with the economy impacts, the ever-increasing morbidity and mortality due to COVID-19 is the biggest setback. The prevalence of epidemics accentuates or creates new stressors. The aim of our study is to determine the effect of the COVID-19 pandemic on mental health in the Indian population and their coping strategies. We found out anxiety as the prevalent problem among the participants and being female and under medical stream were associated with anxiety. Women need special attention as they were more vulnerable than evil. Finally, policymakers also need to care for younger adults, mostly students and individuals under the medical stream.
Energy Medicine
In this textbook, Dr Karl-Heinz Rauscher introduces Healing Voices Rainbow, a shamanic healing method which he has developed over the last 25 years and employs daily in his practice and online worldwide in combination with symptom constellations. Dr Rauscher has presented these healing methods in seminars and individual therapies in 16 countries and four continents, proving the effectiveness of treatment with Healing Voices Rainbow in combination with symptom constellations across different cultures. The book opens up two valuable and extremely effective healing methods in the field of energy medicine that usefully complement and enrich conventional medical treatments. As Dr Rauscher himself puts it, this book is his legacy as a doctor to the world. https: //www.dr-rauscher.de/en/buch-healing-voices-rainbow
A Different Approach to Auriculomedicine
Research is endless, but we feel we have taken an important step by simplifying the detection of essential points. Being able to isolate these points enables us to analyse them in order to arrive at proper diagnoses. It provides practitioners with a simple tool with which to direct their complementary examinations and test for the most appropriate treatments. That is the whole point of the method. It will now be easier to develop tests to make accurate diagnoses. This is the direction which we are inviting you to take.
Toxic Sexual Politics
A bold expos矇 of how the very foundation of toxicology has been contaminated by sexist and racist ideologies The first critical understanding of the field of toxicology from a feminist and antiracist perspective, Toxic Sexual Politics asserts that the science of toxicants must be held accountable for the uneven distribution of toxic pollution along racial and sexual lines. Drawing upon in-depth interviews and extensive ethnographic and archival research, including participant observations in toxicology classrooms, conferences, and laboratories, Melina Packer urges environmental health advocates to place toxicant science within its masculinist, militarist, and eugenicist history. Toxic Sexual Politics shows how the founding fathers of U.S. toxicology were ideologically aligned with the chemical industry, inventing a science that could "make chemicals safe," as opposed to one that could adequately protect planetary health from toxicants' hazards. While many toxicologists today are critical of the chemical industry, they continue to rely on the highly limited tools of toxicology as accurate measures of toxicity, as do government regulators, the courts, and environmental advocates. Unlike most critiques of the chemical industry and narratives of environmental health movements, Toxic Sexual Politics refuses to take the science at face value. By focusing on the sexist, racist, and ableist biases reinforced by toxicology, Packer powerfully argues that this scientific discipline reproduces the very same white supremacist and heterosexist logics that generated environmental injustices in the first place. The field of toxicology can explicitly confront chemical corporate power by building from queer, feminist, anti-ableist, and antiracist movements for environmental and reproductive justice.
Oxford Handbook of Addiction Medicine
Psychoactive substance use ranks among the five top risk factors contributing to the global burden of disease. Substance use disorders can cause, mimic, underlie, or complicate a large number of medical and psychiatric conditions. In recent years, there has been a rapid increase in non-substance forms of addiction such as gambling, internet gaming, and various other behavioural addictions. The ability to diagnose addictive disorders and initiate appropriate management is a responsibility for all health professionals.Addiction Medicine, now in its third edition and published in the renowned Oxford Medical Handbook series, is the result of many years' preparation by a group of colleagues who are clinicians, teachers, and researchers in the addictive disorders field. The handbook is a contemporary, broadly-based, and clinically grounded text that summarises the scientific basis and practice of addiction medicine. It provides practical guidance on clinical management but with a sound background of pharmacology, neurobiology, psychology, and epidemiology and public health. It seeks to provide approaches to minimising harm from psychoactive substances and addictive behaviours, both at an individual and a societal level. The new edition has been expanded greatly. In addition to the behavioural addictions, it covers a broader range of psychoactive substances. There are new chapters on Screening and brief interventions and on Digital health approaches. It also continues to be international in scope, with the editors and contributors drawn from over 30 countries worldwide.The handbook is intended as a concise and practical guide for students, trainees, and qualified practitioners of medicine, nursing, psychology, and other health professionals. In particular, it is designed for students and post-graduate trainees and fellows in addiction medicine, internal medicine, psychiatry, emergency medicine, pain management, gastroenterology, and general medical (family physician) practice. It is also useful and relevant to nurses, particularly those working as specialists in addictive disorders, clinical psychologists, psychologists and counsellors, and social workers and for staff in multidisciplinary agencies which provide help, support, and treatment for people with addictive disorders.This unparalleled guide contains everything you need to know to assist in the assessment, diagnosis, and clinical management of patients with substance use and related addictive disorders
Student's Guide to Pharma Biochem
Welcome to Student's Guide to Pharma Biochem: Quick Tables & Memory Shortcuts, a dedicated resource for B.Pharm 2nd-semester students designed to make the study of biochemistry straightforward, visual, and easy to remember. This guide is a comprehensive yet concise collection of biochemical concepts presented in a highly accessible, student-friendly format. It is crafted specifically for students who seek an efficient and effective way to grasp the fundamentals of pharmaceutical biochemistry and prepare for exams with confidence.
Natural Compounds Applications in Drug Discovery and Development
Nature is a valuable source for the development and design of drug lead compounds that could significantly impact the treatment of serious diseases, enhancing health and wellbeing. Herbal systems play a fundamental role in healthcare, as 60% of chemotherapeutic agents are derived from natural sources. The emergence of cutting-edge technologies and methods that improve the drug design process has provided new ways of processing complex natural products, using their structures to develop new and innovative drug candidates with superior properties. Current drug discovery and development trends focus on the latest applications of natural products in the fight against some of the most difficult-to-treat diseases.In this light, the Special Issue covers a wide range of topics that provide new insights into exploring the vast array of natural products and underlines the recent advances and applications in the field. The articles of the Special Issue emphasize researchers' efforts to combat various cancers, inflammation, and diabetes by applying extraction, synthesis, and computational techniques in conjunction with experimental testing to deliver better therapeutic candidates with fewer side effects, ultimately leading to safer, more effective, and affordable treatments for patients. By integrating advanced scientific techniques with natural biodiversity exploration, it ensures that the potential of natural products is fully explored in an attempt to address unmet medical needs.
Foundations of Network Pharmacology
Network pharmacology is an interdisciplinary approach that integrates systems biology, bioinformatics, and pharmacology to study the interactions between drugs and biological networks. It emerged as a response to the limitations of traditional pharmacology, which often focuses on single targets and may not account for the complex interactions within biological systems. A new science called network pharmacology combines systems biology, bioinformatics, and pharmacology to comprehend the intricate relationships that exist between medications, targets, and illnesses. Network pharmacology adopts a comprehensive approach, taking into account the complex web of interactions within biological systems, in contrast to traditional pharmacology, which frequently concentrates on specific drug-target interactions.
Pulse of Life
This book serves as a bridge between ancient Ayurvedic wisdom and contemporary wellness practices, focusing on Nadi Parikshan (pulse diagnosis). It highlights the timeless relevance of decoding bodily rhythms through the pulse to foster holistic health and well-being.Core Themes: Ancient Wisdom, Modern Context: The book traces the roots of Nadi Parikshan in classical Ayurvedic texts, illustrating its evolution as a sophisticated diagnostic tool. It argues for its importance in understanding not just physical ailments but also emotional and spiritual health.Science Behind the Art: Nadi Parikshan is both intuitive and analytical. The book unpacks its scientific underpinnings, exploring how pulse rhythms correlate with the Tridoshas (Vata, Pitta, Kapha), Prana (life force), and the body's physiological and psychological states.Techniques and Methodology: Detailed descriptions of pulse examination techniques are provided, highlighting: The practitioner's approach to feeling and interpreting the pulse.Variations in pulse based on doshas, dhatus and also the diseases.Subtle cues for identifying imbalances in doshas and dhatus (body tissues).Integration with Modern Medicine: The book emphasizes how traditional pulse analysis complements modern diagnostic tools. It envisions Nadi Parikshan as a non-invasive, personalized health assessment method that aligns with the growing emphasis on preventive healthcare.Decoding Rhythms for Holistic Wellness: The pulse is positioned as a window to the body's internal universe. By interpreting its rhythms, practitioners can decode patterns of health, imbalance, and vitality. The book also explores its application in stress management, chronic conditions, and mental health.Key Insights and Takeaways: Timeless Relevance: Nadi Parikshan is not an outdated practice but a vital diagnostic art for today's wellness revolution.Personalized Healing: It underscores Ayurveda's focus on individualized healthcare rather than a one-size-fits-all approach.Bridging Gaps: The book advocates for a synthesis of traditional diagnostics with modern wellness paradigms.
Eacvi Handbook of Nuclear Cardiology
Part of the European Society of Cardiology portfolio of titles, the EACVI Handbook of Nuclear Cardiology serves as a user-friendly clinical guide to the field of nuclear cardiology. Covering all aspects of this ever-expanding area, it is an indispensable tool in the diagnosis and management of patients with heart failure (ischemic and non-ischemic), amyloid heart disease, endocarditis, myocarditis, and cardiac sarcoidosis.The handbook includes many images, tables, and bullet points that can be used daily in your busy practice to refresh your memory on various cardiac pathologies. The illustrations are derived from a typical clinical practice and the easy accessible format allows you as a reader to focus on the "typical findings" of various cardiac pathologies. Written by an international collection of experts this concise and practical handbook will appeal to students, trainees or advanced users; cardiologists, radiologists, cardiac surgeons or technicians, in their everyday practice.
ML for Target Identification & Validation in Drug Discovery
Machine Learning Approaches for Target Identification and Validation in Drug Discovery examines the transformative role of machine learning (ML) in enhancing the drug discovery process. The introduction highlights the importance of accurate target identification and validation, while subsequent sections delve into various ML algorithms for predicting potential drug targets based on biological data. Gene prioritization methods are discussed, showcasing how ML can effectively rank disease-associated genes. Additionally, the integration of ML with knowledge graphs is explored, illustrating how these tools enhance data connectivity and decision-making. Finally, the importance of information extraction through data mining and natural language processing is addressed, illustrating how these approaches help researchers extract valuable insights from large datasets, thereby advancing the field of drug discovery.
Evaluation of Quality of Life in Knee Osteoarthritis Patients
Knee osteoarthritis related disability is high in the elderly population. Patients feel difficulty in walking/ jogging, an important and easy option to reduce the risk of cardiovascular disease. Stiffness, pain, other knee related symptoms may limit the patients' functional status and recreational activities. Thus, these individuals suffer from progressive impact on their activities of daily living and leads to loss in leisure, social life, sleeping quality and thus decrease in their quality of life. Worse QoL in patients with knee OA is also associated with severity of clinical manifestations and radiographic features. The QoL of knee OA patients was found to be significantly poorer than QoL compared to healthy patients (Non-OA patients).
The Transradial Handbook
Access site techniques for invasive cardiology and interventional radiology procedures have undergone rapidly evolving technological advances, with radial access offering important benefits for patients and health care systems. This book provides a concise practical guide to the practice of transradial procedures in both specialties.
The Transradial Handbook
Access site techniques for invasive cardiology and interventional radiology procedures have undergone rapidly evolving technological advances, with radial access offering important benefits for patients and health care systems. This book provides a concise practical guide to the practice of transradial procedures in both specialties.
Pharmacogenomics in Personalized Medicine
Pharmacogenomics in Personalized Medicine explores the relationship between an individual's genetic makeup and their response to medications. The book delves into how genetic variations influence drug metabolism, efficacy, and safety, paving the way for more personalized treatment approaches. It highlights the potential of pharmacogenomics to optimize drug therapy, reduce adverse drug reactions, and improve overall patient outcomes. The text also discusses challenges in implementing pharmacogenomics in clinical practice, such as the need for genetic testing, regulatory considerations, and integration with healthcare systems.
Oxford Clinical Guidelines: Newly Qualified Doctor and Oxford Handbook of Clinical Medicine Pack
Quality by Design (QbD) in Pharmaceutical Development
Quality by Design (QbD) is a systematic approach to pharmaceutical development that emphasizes building quality into a product from the outset, rather than relying solely on end-product testing. This approach involves understanding the science behind formulation and manufacturing processes, identifying critical quality attributes (CQAs), and designing processes that consistently deliver products meeting predefined quality standards. QbD integrates risk management, process optimization, and continuous improvement throughout the product lifecycle. It encourages the use of scientific knowledge, data analysis, and process control tools to enhance product quality, reduce variability, and ensure regulatory compliance. By focusing on design and process development, QbD aims to improve manufacturing efficiency as well as the safety and efficacy of pharmaceutical products.
Clinical Utility of Optical Coherence Tomography in Ophthalmology
This Special Issue reprint compiles a series of articles focused on the latest advancements in optical coherence tomography (OCT) in ophthalmology. Initially developed to assess the posterior segment, particularly the macula and optic nerve, OCT has since expanded its applications to the anterior segment, enabling a detailed analysis of structures such as the cornea, anterior chamber, and iridocorneal angle. Recent innovations, such as intraoperative OCT, en face OCT, and wide-field OCT, have provided new insights into complex ocular structures such as the choroid, vitreous, lens, and ciliary muscle. These advancements have also improved surgical precision and postoperative evaluation in various ophthalmological subspecialties, including the retina, cornea, and glaucoma. This Special Issue reprint presents a collection of original research articles and reviews that discuss the current state of the art, address existing knowledge gaps, and highlight the clinical impact of OCT in enhancing the diagnosis, treatment, and management of a wide range of ophthalmic conditions.
Selected Papers from the pHealth 2022 Conference, Oslo, Norway, 8-10 November 2022
This reprint addresses healthcare transformation towards personalized, participative, preventive, predictive, and precision medicine (5P Medicine) with the support of new technologies such as micro-, nano-, and bio-techniques, as well as artificial intelligence and learning systems. These technologies offer big opportunities, but also bear big challenges regarding ethics including security, privacy, and related policies to be managed. The resulting multidisciplinary, highly dynamic, and context-sensitive 5PM ecosystems shall enable consistent and comprehensive interoperability between all actors, domains, specifications, and work products based on the understanding of the real-world business system and its development process viewpoints. This requires the representation and management of knowledge from different domains and their actors, using their methodologies and languages, but also individual skills and experiences. The outcome is a system-oriented, architecture-centric, ontology-based, policy-driven approach allowing for the formal representation and management of health ecosystems, including their standardized integration and interoperability in ISO 23903 Interoperability and integration Reference Architecture. The reprint describes the principles, methodologies, and standards needed for successfully managing the transformation of health and social care, exemplified by practical projects and solutions. The reprint is based on papers published in the context of the pHealth 2022 Conference in Oslo, Norway, which have been strongly extended regarding their focus and size.
Fascia, Function, and Medical Applications
Following its predecessor, the second edition is essential reading for medical and allied health practitioners who want to bring scientific insights of the importance of fascia to human health into their clinical practices.
Advances in Geriatric Diseases
This special issue focuses on research on relevant topics in geriatric medicine, discussing the condition of cognitive and functional decline and age-related diseases as well as polypharmacy and risk stratification. New insights into modern medicine pertaining to the issue of aging are required in order to adequately treat older chronic patients with comorbidity and polypharmacy, who should undergo complex and minimally invasive treatments.
Advances in Skull Base Tumor Surgery
This reprint of the Special Issue "Advances in Skull Base Tumor Surgery: The Practical Pearls" from the Brain Sciences Journal presents a curated collection of articles that exemplify the most complex surgical procedures for skull base surgery. This reprint serves as an invaluable resource for novice and seasoned skull base surgeons.
Traditional Folkcure Plants in the Indian System of Medicine
The Indian system of medicine, particularly Ayurveda, has a rich tradition of utilizing medicinal plants for healing and wellness. Traditional folk cures often draw from local flora, integrating plants into daily practices for both preventive and therapeutic purposes. Here are some key plants commonly used in folk medicine across India: Tulsi (Holy Basil): Revered as a sacred plant, Tulsi is known for its anti-inflammatory and antioxidant properties. It is often used in teas and decoctions to relieve respiratory ailments, reduce stress, and enhance immunity. Neem (Azadirachta indica): Known for its purifying properties, Neem is used to treat skin conditions, infections, and as a natural insect repellent. Its leaves, bark, and oil are commonly applied in various formulations to support detoxification and enhance overall health. Amla (Phyllanthus emblica): Amla is rich in vitamin C and antioxidants. It is traditionally used to boost immunity, improve digestion, and enhance skin health. Amla juice or powder is often consumed for its rejuvenating properties. Turmeric (Curcuma longa): Widely known for its anti-inflammatory and antimicrobial effects.
Ruptured Supratentorial Cerebral Artery Aneurysm with Large Intracerebral Haematoma
The ruptured aneurysm with an intracerebral haematoma is a commonly encountered neurosurgical emergency. The options for management of this situation have evolved with the changes in neurovascular surgery training and widespread use of endovascular techniques for aneurysm occlusion. This Element will discuss the differences between subarachnoid haemorrhage with or without an intracerebral haematoma including presentation, imaging and outcomes. The authors present their preferred surgical strategy including practical guidance on how to handle difficult situations such as the intra-operative rupture.
Ruptured Supratentorial Cerebral Artery Aneurysm with Large Intracerebral Haematoma
The ruptured aneurysm with an intracerebral haematoma is a commonly encountered neurosurgical emergency. The options for management of this situation have evolved with the changes in neurovascular surgery training and widespread use of endovascular techniques for aneurysm occlusion. This Element will discuss the differences between subarachnoid haemorrhage with or without an intracerebral haematoma including presentation, imaging and outcomes. The authors present their preferred surgical strategy including practical guidance on how to handle difficult situations such as the intra-operative rupture.
The Quintessence Tantras of Tibetan Medicine
The Quintessence Tantras of Tibetan Medicine is a thorough, detailed, and systematic analysis of the characteristics of healthy and diseased bodies. Discussed are the diagnostic techniques of pulse and urine analysis, principles of right diet, right lifestyle, and behavioral factors--and a treasury of knowledge about the beneficial applications of herbs, plants, spices, minerals, gems, etc. Also included are the subtle and psychological techniques of therapeutics, and the ethics and conduct required of a Tibetan physician--a warrior-like person equipped to overcome even the most formidable internal and external obstacles.
Study of the Dispensing of Anti-Cancer Drugs
An anti-cancer drug is designed to fight cancer, whatever its mechanism. It is designed to destroy or stop the growth of malignant cells, or to help the body get rid of them more effectively. Dispensing is the pharmaceutical act that combines the dispensing of drugs, the pharmaceutical analysis of the medical prescription and the provision of information and advice necessary for the proper use of drugs (37).To study the dispensing of anticancer drugs in the M'PEWO private pharmacy from August 2023 to July 2024.This was a cross-sectional study with a 6-month survey period from December 1, 2023 to May 31, 2024.The study involved 102 registered prescriptions belonging to 85 patients. Women were more frequent. The [46 - 60] age group accounted for 37.7%. The mean age was 48.86 簣 16.45 years. Breast and gastric cancer were the most common, each accounting for 14.1%. Almost all prescriptions were written by medical specialists. All were legible, and most were sealed and dated. Availability of anticancer molecules was 99%...
Protocols of Actinomycetes
This book will cover basics to recent protocols for drug discovery from actinobacteria. It will be helpful for the pharmaceutical industries and researchers to develop new antibiotics from actinobacteria and would be used in support of future research in drug discovery.
Research on bionanocomposites with therapeutic properties
Did you come across this book by accident?This book was developed, and redeveloped, between the years 2021 and 2024. More relevant, and more competent, with each new appearance.Bio-Nano-Composite materials are the most recent pharmaceutical discovery of this century, with all their beneficial therapeutic effects and healthy natures for humans and their ecosystems.A well-written book, to be read at least once in a lifetime, for pharmaceutical biotechnologists.
Advanced Imaging in Orthopedic Biomechanics
The aim of this Special Issue is to provide the reader with a comprehensive overview of investigations demonstrating the great support that advanced medical imaging provides for orthopedic biomechanics. The contributions in this issue are based on different imaging modalities and various data processing techniques and cover different anatomical compartments, highlighting the multidisciplinary and translational nature of the investigative procedures used.
