Imaging cerebral venous thrombosis
Cerebral venous thrombosis (CVT) is a diagnostic and therapeutic emergency that can lead to serious sequelae. Early diagnosis and prompt treatment can reduce the morbidity and mortality associated with this pathology. Clinical polymorphism underlines the importance of cross-sectional imaging for accurate diagnosis. Both CT and MRI provide direct evidence of venous occlusion, but MRI is superior to CT in detecting a clot in cortical or deep veins. Thrombus appearance on MRI is variable over time. MRI provides a better assessment of any associated venous infarcts. Finally, it helps to orientate the etiological diagnosis, to look for associated lesions and to rule out certain differential diagnoses.
Breast imaging of benign lesions in general practice
Breast Imaging of Negligible Lesions in General Practice is designed specifically for general practitioners to introduce them to the fundamental principles and practical applications of breast imaging in the diagnosis and follow-up of breast lesions. Through this guide, we will explore the various imaging modalities such as mammography, breast ultrasound and MRI. They will learn not only how these techniques are used in clinical settings to assess and manage breast pathology, but also how they fit into an overall treatment plan for patients. This textbook aims to enrich their academic learning with practical knowledge that will prepare you for thoughtful and informed clinical interventions. The aim is to equip them with the tools they need to interpret imaging results competently and to collaborate effectively with radiologists and other specialists in patient care.
Waste Clearance in the Brain
Waste Clearance in the Brain provides an in-depth exploration of the brain's essential waste clearance systems, focusing on the glymphatic and cerebrospinal fluid pathways. This book examines the body's natural defense mechanisms against harmful substances like abnormal proteins and metal deposits linked to neurodegenerative diseases such as Alzheimer's. With clear explanations, it covers how foreign pathogens and harmful proteins are managed by cerebrospinal fluid, brain vasculature, and the meningeal lymphatic systems. It also discusses cutting-edge research on therapeutic approaches targeting the blood-brain barrier and brain cell regulation. Key Features: - Comprehensive overview of brain waste clearance pathways and systems- Examination of abnormal protein and metal deposition impacts on brain health- Insights into potential therapies for neurodegenerative diseases- Discussion on the brain's vascular and immune system roles in waste clearance
Pleural tuberculosis
Pleural tuberculosis is one of the most frequent extra-pulmonary tuberculoses. Its incidence has been rising steadily in recent years. However, this form of tuberculosis has received little attention in the literature. The aim of our study was to investigate the epidemiological, clinical and evolutionary profile of pleural tuberculosis.We conducted a retrospective descriptive study of 50 patients presenting with pleural tuberculosis who were diagnosed and followed up in the Pneumology Department at Mohamed Taher Maamouri Hospital, Nabeul.The mean age of our population was 40.4 years. Complaints were dominated by respiratory symptoms. Chest radiography revealed pleural opacity in all cases. The diagnosis was established by the presence of acid-fast bacilli on direct examination of pleural fluid in only one patient. For the remaining 49 cases, the diagnosis was confirmed by pleural biopsy. Anti-tuberculosis treatment was completed for 47 patients, resulting in cure in all cases. Radiological sequelae were noted in 16 patients.
Stom-VIH-Soft a tool for learning about HIV/AIDS
At present, HIV/AIDS is a serious problem affecting Cuba and especially the province of Santiago de Cuba, and maxillofacial surgeons play a fundamental role in its detection, prevention and treatment. For this reason, the academic training of stomatologists and maxillofacial surgeons needs to integrate knowledge acquired in the different subjects, which is why it is necessary to develop and apply new teaching support techniques such as didactic materials.To prepare a didactic material to support the teaching-educational process for the Stomatology career that integrates the fundamental knowledge about HIV/AIDS and its relationship with medical care in oral surgery.
Beyond the Blueprint - Decoding the Elegance of Gene Expression
Beyond the Blueprint - Decoding the Elegance of Gene Expression is a captivating exploration into the fundamental processes that underpin the intricate workings of life itself. Delving deep into the realm of genetics, this book unveils the mesmerizing world of gene expression - the remarkable mechanism by which the information encoded in our DNA is translated into functional proteins and ultimately shapes every aspect of our being. With a keen focus on the crucial players in this symphony of life, readers will embark on a journey to uncover the core elements of gene expression. From the orchestration of transcription factors and RNA polymerases at promoter regions to the influence of epigenetic modifications on gene regulation, the book paints a comprehensive and accessible picture of this dynamic process. As the narrative unfolds, readers will be captivated by the role of non-coding RNA in gene regulation and how environmental factors can subtly alter gene expression patterns. Moreover, the book delves into the interplay of gene expression during embryonic development, illuminating the incredible transformations that occur as cells differentiate into specialized tissues. Embracing the forefront of scientific advancements, Beyond the Blueprint - Decoding the Elegance of Gene Expression also examines the revolutionary realm of genetic engineering, showcasing how we can now manipulate gene expression for potential therapeutic applications and reshape the course of human evolution. With clarity and enthusiasm, this book seeks to demystify the complexities of gene expression, appealing to both seasoned researchers and curious minds alike. Beyond the Blueprint - Decoding the Elegance of Gene Expression promises to inspire a profound appreciation for the elegance of gene expression and its profound impact on the unfolding story of life.
3D Printing in Oral and Maxillofacial Surgery
"Printing Precision: Revolutionizing Oral and Maxillofacial Surgery with 3D Technology". Dive into the transformative power of 3D printing in oral and maxillofacial surgery. This book illuminates the journey from digital design to life-changing surgical outcomes, showcasing breakthroughs in custom implants, patient-specific models, and innovative workflows. By blending cutting-edge technology with surgical artistry, it redefines possibilities for reconstructive and functional care.
Sociodemographic and Clinical Profile of Elderly People at Risk of Falling
Population ageing is one of society's most significant events and over the years it has become increasingly significant, particularly in developing countries. In Brazil, the population segment represented by the elderly is the fastest growing, and by 2050, projections suggest that 30 per cent of Brazilians will be represented by people aged 60 or over, at which point the country will rank sixth among those with the highest number of elderly people. At the same time as demographic changes, there are changes in morbidity and mortality patterns characterised by an increase in chronic degenerative diseases and factors that can result in dependency and a lower quality of life, particularly falls. In addition to its debilitating nature, falls are important in the public health scenario due to their high prevalence, which burdens the health system as the demand for medical and hospital care to treat associated injuries increases. There is still a need for studies on the factors associated with falls in primary care, given the growing number of elderly people assisted by the Family Health Strategy (ESF).
Bisphenol A
Bisphenol A (BPA) is a chemical widely present in our daily lives, incorporated in a multitude of plastic products and food coatings. However, concerns about its impact on human health and the environment are growing. This book takes an in-depth look at this highly topical issue.It offers a detailed analysis of the presence of BPA in the environment and in food, explaining the different modes of contamination and the most vulnerable populations. The book highlights the associated health risks, including endocrine disruption, and explores the scientific and regulatory challenges posed by this controversial substance.Finally, the book presents practical solutions, highlighting alternatives to BPA and proposing strategies to reduce risks for both consumers and industry.
Pectoralis Major Myocutaneous Flap in Head and Neck Surgery
Reconstructions in head and neck surgery, especially of the higher regions such as the orbit, are a routine challenge for those who operate on large lesions in particular and non-ideal conditions. Knowing how to predict whether your chosen course of action will be adequate to guarantee the success of the procedure and the patient's rehabilitation, before starting surgery, using only anthropometric measurements and the relationships between them, is part of successful planning. This possibility is demonstrated in this book, in which the author compares the elevation and rotation of the pectoralis major myocutaneous flap in cadavers and live specimens, and their anthropometric relationships, calculating the average length of the vascular pedicle and its reach.
Integrated health management
The past Covid-19 pandemic has come to mean that we must take a break, it is time to reflect and consider new directions in health-related matters. It is time to innovate in the old Flexnerian model which, in spite of all its application and success in the different countries of the world, is not the solution for the serious problems in the order of public health as has been demonstrated with the strong economic implications at world level.With the arrival of the new millennium, which brought with it new technologies that could be used in medicine, it is imperative to change the health model in all areas, in the sense of moving from a curative model to a predictive one, for which physicians must acquire new competencies, not only in the field of medicine but also in having knowledge of administration and thus be able to establish a comprehensive health management, optimally managing resources that a country has, so as not to have to spend huge economic assets by the arrival of serious events as happened in the past, where governments had to dispose of what was not budgeted.
Miraculous Potential of Sesame in Wound Healing Activity
Sesame (Sesamum indicum L.) has potential to promote wound healing due to its antioxidant and anti-inflammatory properties: - SesamolA lignan found in sesame seeds, sesamol is a main antioxidant in processed sesame oil. It can be applied topically to the skin, where it can rapidly cross skin layers and be absorbed into the bloodstream. - Sesame oil extractContains lignans like sesamin and sesamolin, which have antioxidant activity. Sesame oil extract may have wound-healing properties due to its antioxidant capacity and ability to scavenge free radicals. - Sesame seeds and oilWhen applied topically or administered orally, sesame seeds and oil can increase the breaking strength, dry weight, and hydroxyproline content of granulation tissue.
Anthroposophically Oriented Medicine and Its Remedies
This booklet offers a clear introduction to anthroposophic medicine in response to commonly asked questions on the subject. It includes a basic discussion of illness and healing, an historical view of remedies, and a description of the new anthroposophic methods of preparing remedies.
Anthroposophical Medicine and Therapies for Cancer
Cancer is the second leading cause of death today. Many who contract this disease become responsible patients who want to help decide the treatment they receive and often demand new strategies for fighting cancer.In this book, the reader learns about the treatment concept at the anthroposophic medical Lukas Clinic in Arlesheim, Switzerland, which emphasizes mistletoe therapy, as well as proven healing methods of conventional, allopathic medicine. One is introduced to the healing effects of this unusual plant and the ways in which it is applied. Also included is information on how nursing, physical therapy, diet, and artistic therapies can support cancer treatments.
Guyton & Hall Physiology Review
Whether you're preparing for a course exam or for the physiology portion of the USMLE Step 1, Guyton and Hall Physiology Review, 5th Edition, is your go-to resource for effective, efficient study. This practical review tool is an ideal companion to the world's foremost physiology textbook, offering more than 1,000 questions and answers to improve your understanding of this complex subject.Thorough reviews of all major body systems, with an emphasis on system interaction, homeostasis, and pathophysiologyMore than 1,000 board-style questions and answers on the most essential, need-to-know concepts prepare you for your exams, including the physiology portion of the USMLE Step 1Every question is cross-referenced and aligned to Guyton and Hall Textbook of Medical Physiology, 15th Edition, highlighting important concepts and featuring direct page references to specific questionsAn eBook version is included with purchase. The eBook allows you to access all of the text and figures, with the ability to search, make notes and highlights, and have content read aloud
Oral candidiasis in diabetics
Oral candidiasis is the fungal infection most frequently encountered in diabetic patients, caused mainly by a yeast of the genus Candida. Although Candida is a normal commensal of the oral cavity, many factors can predispose to the occurrence of oral candidiasis, including extreme age, hyperglycemia, immune dysfunction, underlying diseases such as heart disease, hypertension, liver disease, dysthyroidism, infectious diseases linked to the increased use of long-term antibiotic therapy, particularly for angina, and covid 19.Inadequate oral hygiene, smoking, the use of long-lasting dentures and the presence of dental caries are also contributing factors.Systemic health is linked to oral health, particularly in diabetics, increasing the need for dental and medical management of the patient.
Digital Dentistry in Prosthodontic
Advancements in digital imaging, CAD/CAM technology, internet communication, and new materials have transformed dentistry, improving diagnostics, treatment, and patient care. These technologies enhance aesthetics, reduce errors, and streamline procedures, making modern dentistry more efficient and convenient. Tools like digital radiographs and CAD/CAM ceramics have revolutionized prosthodontics, offering precision and reliability.Dubbed the "golden age" of dentistry, the field is increasingly digitized, from teaching and patient education to clinical applications. CAD/CAM dentures are gaining acceptance, though challenges like capturing dynamic jaw movements for digital impressions persist. Collaborative research and refinement of protocols are essential to fully realize the potential of these advancements, paving the way for enhanced patient care, education, and innovation in complete denture therapy.
Severe malaria in children aged 6 to 60 months
Severe malaria remains a real public health problem in Matadi in particular and in the DRC in general.A retrospective descriptive study of 200 children aged between 6 months and 5 years admitted to the paediatric ward for severe malaria was carried out at the Kinkanda/Matadi provincial referral hospital between January 2022 and December 2023.The figures relating to the frequency of the anaemic form and neuromalaria, as well as the mortality rate for severe malaria in children under 5 during this study period, show that malaria is still a public health problem despite the many efforts made, and highlight the scale of the problem, as well as its preventable nature, which calls on all those involved to take action to better adapt strategies to the local context in order to prevent avoidable deaths now and in the future.
Arabian Medicine
Embark on a transformative journey through the annals of history with "Arabian Medicine" by E.G. Browne. In this meticulously crafted narrative, Browne illuminates the profound influence of Arabian physicians on the development of medical science, spanning from the golden ages of Islamic scholarship to the corridors of modern medicine.Step into the world of Arabian medicine as Browne delves into the meaning of the term itself, exploring its roots in the rich tapestry of Arabian and Islamic history. Discover the intricate transmission of Greek learning and the invaluable contributions of Syrian and Persian scholars. Through captivating anecdotes, Browne paints a vivid picture of the intellectual landscape, highlighting the aptitude of Arabic for scientific pursuits.Delve deeper into the evolution of scientific terminology in Arabic and uncover the fascinating debates surrounding dissection practices among Muslim scholars. Journey through time as Browne introduces four early Persian medical luminaries, including Avicenna, whose works continue to shape medical discourse to this day.Experience the pulse of Arabian medicine during the Crusades, where tales of remarkable cures and psychotherapeutic practices echo through history. Browne masterfully intertwines the realms of literature and healing, shedding light on the enduring legacy of Arabian wisdom.Trace the footsteps of the Moors in Spain and their profound contributions to medical literature. Explore the vibrant School of Toledo and immerse yourself in the biographical works that paved the way for modern medicine. From the introduction of European medical practices into Muslim lands to the intricate cosmogony of Muslim scholars, Browne uncovers the interconnectedness of civilizations.Whether you're a seasoned scholar or an enthusiastic seeker of knowledge, "Arabian Medicine" promises to captivate and enlighten. Browne's eloquent prose and meticulous research invite readers to unlock the hidden treasures of Arabian knowledge and delve into the timeless wisdom that continues to shape our understanding of medicine.
The Doctor's Perspective
The Doctor's Perspective: A Look at Testosterone, Wellness and Performance explores the intricate relationship between hormones, metabolic health, and performance, offering an evidence-based analysis of these often-misunderstood topics. Written by a physician, this book delves into the science behind testosterone replacement therapy (TRT), anabolic steroids, and performance-enhancing drugs (PEDs), separating medical facts from myths and misinformation. It addresses critical men's health issues such as hypogonadism, cardiac and prostate health, obesity, and the psychological effects of hormonal imbalances. The book also examines emerging compounds like selective androgen receptor modulators (SARMs) and nootropics, evaluating their benefits and risks. From the history of testosterone's discovery to its modern medical applications, the author provides a thorough review of therapies and their implications. Each chapter integrates an evidence-based approach with practical insights, offering readers a balanced perspective on these controversial topics. With discussions on nutrition, supplements, and the ethical dimensions of drug use in sports, it serves as a comprehensive guide for healthcare professionals, fitness enthusiasts, and individuals seeking clarity in the evolving landscape of wellness. Ultimately, this book aims to empower readers with the knowledge to make informed decisions about their health, bridging the gap between clinical expertise and everyday concerns. The Doctor's Perspective is a must-read for anyone navigating the complexities of hormones, health, and human potential.
The Body under Acupuncture
Acupuncture has been systematically taught and practised in the West based on the understanding of two medical rationalities: Traditional Chinese Medicine and Biomedicine. The purpose of this book is to discuss how understanding the explanatory theories of acupuncture creates a field of legitimacy for this practice, but does not provide a deeper understanding of the practice of acupuncture itself.
Therapeutics for nasosinusal polyposis
Nasosinus polyposis is a chronic inflammation of the nasosinus cavities, requiring tailored, personalized management. Treatment is based primarily on intranasal corticosteroids, which reduce inflammation and polyp size, while improving symptoms such as nasal congestion and loss of smell. In the event of severe flare-ups, temporary recourse to systemic corticosteroids may be considered, although their use should be limited due to side effects. If symptoms persist despite medical treatment, endoscopic endonasal surgery can remove polyps, restore sinus ventilation and improve the administration of local corticosteroids. For severe or refractory forms, biotherapies, notably monoclonal antibodies, target the underlying inflammatory mechanisms and offer promising results. Finally, long-term follow-up, combining topical treatments, management of aggravating factors and management of comorbidities, is crucial to prevent recurrences and sustainably improve patients' quality of life.
Distinctive features of asthma in high school students
Asthma in high school students is often under-diagnosed, which can affect their academic performance. High school students with asthma may face challenges related to the management of their condition, especially in the school environment. We conducted this study to investigate the particularities of asthma in high school students.The mean age of onset of asthma symptoms was 11.48 簣 4.08 years. The average duration of asthma was 39.95 簣 41.35 months. Allergic manifestations in addition to asthma (rhinitis, conjunctivitis) were noted in 404 patients (82.3%). Asthma was mild in 183 patients (37.3%), moderate in 300 (61.1%) and severe in 8 (1.6%). 357 patients (72.7%) were well controlled.Asthma is a common condition among high-school students, which can lead to absences and reduced performance. School pressure and sports activities can exacerbate symptoms, making disease management crucial.
Emulsifying properties of shea butter Produced in Mali
The Shea tree or "Shea yiri", meaning "tree of life" in the Bambara vernacular, is a plant native to the arid regions of sub-Saharan Africa. Unrefined shea butter is the oleaginous substance obtained from the kernel of Vitellaria paradoxa C.F. Gaertn, a member of the Sapotaceae family, by manual or mechanical methods. Known for thousands of years, this butter is a highly prized resource among African populations, who already used it as a phytomedicine for its anti-inflammatory, anti-hemorrhoidal, relaxing, cough-reducing, antioxidant and healing properties... In addition to these medical properties, shea butter also has other properties, and is used in cosmetics for its emollient, moisturizing, hair care, baby and mother care, photo-protective and stretch mark prevention properties... Butter was also used as a foodstuff and as a raw material in the manufacture of household soaps (kabacorouni in the Bambara vernacular). Today, this fatty substance is highly prized in both the cosmetics and pharmaceutical industries.
Problems and Prospect of Small, Medium Scale Enterprises
Small and medium-sized enterprises (SMEs) have a long history of success, often evolving from small family businesses into large multinational companies over many decades. Contrary to the common perception of SMEs as small retail trades run by family units, they actually encompass a wide range of activities including production, distribution, retailing, and services.With the right support, SMEs in Nigeria could spark an industrial revolution within the next twenty years, similar to what's happening in Asian countries like India, Singapore, Korea, and Taiwan. In these countries, small factories managed in villages produce significant goods and provide support services to large industrial giants.This study aims to highlight the nature and scope of SMEs, their challenges, and prospects. It seeks to address their problems and explore how Nigeria can leverage the potential of SMEs to improve its socio-economic situation.
Maxillofacial Defect and Rehabilitation
Maxillofacial defects refer to injuries, congenital conditions, or diseases that affect the face, jaws, and related structures. These defects can result from trauma, tumors, infections, or congenital abnormalities and can severely impact a person's appearance, functionality, and quality of life. Rehabilitation of these defects involves a multidisciplinary approach that combines surgical intervention, prosthetics, and therapy to restore both form and function.Treatment strategies depend on the severity and type of defect and may include reconstructive surgery, bone grafting, soft tissue repair, and dental prosthetics. The goal is to restore facial aesthetics, enable speech, improve chewing and swallowing, and enhance overall facial expression. Modern advancements in tissue engineering, 3D printing, and virtual planning have revolutionized the planning and execution of these procedures, leading to better outcomes.The rehabilitation process also involves psychological support to help patients cope with the emotional and social challenges associated with facial disfigurement. Multidisciplinary teams, including surgeons, prosthodontis.
Different Diagnostic Methods for Oral Dryness
Oral dryness is a complex condition, expressed as a physiological deficiency with or without perceived dysfunction. Clinically, oral dryness may vary from a slight reduction in salivary flow with transient inconvenience to severe impairment of oral health and concomitant psychological disposition. Saliva is vital to oral health. Saliva serves multiple functions, including taste, lubrication, and protection during eating. Saliva contains water, mucins, and proline-rich glycoproteins that help with swallowing and taste perception. Saliva protects by washing away microorganisms, containing antimicrobial components such as mucin, histatins, lysozyme, and lactoferrin, and containing specific antibodies to microorganisms encountered. The aim focusing on perceived oral dryness associated with eating was highly indicative of salivary performance whilst the most commonly heard complaints such as perceived oral dryness at night and during the day had no significant correlation with reduced salivary flow rate. This library dissertation aims to evaluate the quality of the evidence for the efficacy of diagnostic methods used to identify oral dryness.
Medical and nutritional therapy for kidney diseases
The creation of a daily nutritional plan that takes all factors into account will allow you to feel good about yourself, and a constant modification of your diet will find an excellent modification in the health of your kidneys. Blood tests should be taken at all times to ensure that your diet is progressing smoothly. In fact, specific diets have been developed to maintain kidney health.
Cytological criteria associated with the luminal phenotype of breast cancer
Fine-needle aspiration biopsy (FNAB) is a rapid, low-cost diagnostic method with low morbidity and risks, which enables early diagnosis of breast cancer - the most common malignant neoplasm in women and the leading cause of cancer death in Brazil. This book is the result of a research project to identify the cytological criteria in the material obtained by FNAB that are associated with the luminal phenotype of breast cancer, which despite being the most common and with the best prognosis, still has no cytological characterisation described.
Managing Ocular Abnormalities in Bardet-Biedl Syndrome
Bardet-Biedl syndrome and Laurence-Moon syndrome are rare autosomal recessive disorders that share a similar clinical phenotype. These syndromes are characterized by progressive features including cone-rod retinal dystrophy, obesity, and hypogonadism in males. Additional clinical manifestations can include learning disabilities, renal abnormalities, and polydactyly. Despite their similarities, Bardet-Biedl syndrome and Laurence-Moon syndrome are distinguished by certain clinical features. This book describes the management of the ocular manifestations of Bardet-Biedl syndrome through new evidence-based therapies.The current treatment options are not curative; they may help slow progression and preserve vision. The combination of citicoline, goji berry, coenzyme Q10, and lutein represents a promising approach for the management of retinal degeneration in BBS patients, though further clinical trials are needed to confirm their efficacy.
Young Onset Dementia Reconsidered
The proposed book will be a positive, solution-based text based on research evidence and best practice about the distinctive issues arising for people living with young onset dementia (YOD) and their families, and the types of support that are helpful. Targeted at social and healthcare students and practitioners, those in the voluntary and community sectors, professionals in training, researchers and those living with YOD and their family members. Eighty percent of the estimated 42,000 people living with YOD in the UK are served by all age dementia rather than specialist YOD services, and staff in these services have little experience and knowledge of, or training in, caring for those with YOD. Often they lack the specialist knowledge to know how to help. Through this book we aim to arm all staff and carers with useful information that will give them confidence to be able to understand and support those affected. As the range of support needs that can arise in YOD is broad, it is hard for staff to keep up with evidence outside their specific discipline, so this work will provide a valuable collection for those wanting to update their knowledge. Students and staff in training for health or social care roles often have generic training with little time in the curriculum for dementia, let alone young onset dementia, and the book will fill this gap. Further, the text is designed to inspire dementia researchers to turn to this under-researched but impactful area. Finally, people with a diagnosis and their family members are often discharged and left to fend for themselves following diagnosis with little to no recourse, support, or literature. This book will be written in an accessible way to provide a valuable source of information for those directly affected by young onset dementia, as well as their family and friends who are often their carers.
Temporomandibular Joint Pain
Temporomandibular joint (TMJ) pain is a prevalent condition that affects the jaw joint and surrounding structures, leading to significant discomfort, functional limitations and diminished quality of life for affected individuals. The temporomandibular joint acts as a hinge connecting the jawbone (mandible) to the skull, allowing for essential functions such as chewing, speaking and swallowing. However, when dysfunction or pain arises in this joint, it can have a profound impact on an individual's daily activities and overall well being. Pain caused by temporomandibular disorders originates from either muscular or articular conditions or both. Distinguishing the precise source of the pain is a significant diagnostic challenge to clinicians, and effective management hinges on establishing a correct diagnosis.
Qualified care for women in labour
Reducing maternal mortality is one of the health indicators whose main element is quality labour and birth care. The International Confederation of Midwives advocates the skills and competences needed to provide quality care throughout the pregnancy-puerperium cycle. The aim of this study was to characterise the nursing professionals who work in childbirth care services and to analyse the essential competences developed by these professionals. This was a descriptive study with a quantitative approach carried out in three maternity hospitals in the city of Londrina. We observed differences in the quality of nursing care provided in the participating institutions. Many essential competences for labour and delivery care are not developed. The institutions need incentives to implement actions based on up-to-date evidence.
Implantable Pressure Sensor Encapsulation for Ventricular Assist Device Control
Autonomous feedback controlled ventricular assists device (VAD) operation promises a plethora of benefits such as increased patient safety, comfort, and reduced healthcare costs. Current generation VADs operate at static pump speeds due to the lack of available biocompatible, long-term stable pressure sensor systems. In this thesis, a pressure sensor encapsulation was developed and integrated in an inflow cannula for a VAD and in an implantable testing platform for animal trials. The encapsulation uses a media separating diaphragm embedded in a Parylene C coating. The approach is expanded to enable optimized diaphragm shapes, which allow significantly better control over the final device characteristics, especially the temperature cross sensitivity. Furthermore, a production processes was developed to minimize assembly induced internal overpressure. The produced capsules showed excellent pressure transmission of more than 99.7 % and a temperature cross sensitivity of less than 266 Pa from 35 簞C to 42 簞C for most capsules. However, a large temperature cross sensitivity was observed from room to body temperature in some capsules, adding relevant drift of 750 Pa (75 % quartile) after 42 days to the measurement. The observed drift is related to the viscoelastic nature of the Parylene C diaphragm and the capsule-to-capsule variation is attributed to production process variations, which can be further optimized. Systematic errors in the pressure transmission, temperature cross sensitivity (TCS), and drift were extracted and correction approaches for each were developed. This enabled the reduction of the pressure transmission error by 50 % by linear correction. A differential measurement approach reduced the temperature cross sensitivity to less than 70 Pa from 35 簞C to 42 簞C and drastically reduced the temperature induced drift to 300 Pa (75 % quartile) after a jump from room to body temperature. Half of all sensors even remained within a +- 100 Pa window in the same tim
A Textbook of PATHOPHYSIOLOGY
Pathophysiology: A Comprehensive Textbook is an essential resource for students, healthcare professionals, and researchers seeking to understand the mechanisms driving disease processes. This textbook bridges the knowledge of physiology and pathology with practical clinical insights, offering a detailed exploration of how diseases develop, progress, and affect the body's normal functioning.The book combines foundational concepts with recent advancements, creating a structured, cohesive framework to clarify complex disease mechanisms. Topics span a broad range, from the physiological basis of diseases and cellular and molecular mechanisms to systemic disorders and the body's responses to injury and infection. Each chapter links pathophysiological principles to clinical relevance, allowing readers to connect theoretical understanding to practical medical scenarios.
Early Exits
With 25 years in end-of-life care and firsthand experience with death, dying, and MAiD, David Maginley explores the unaddressed issues at the heart of our effort to control the final human experience. What drives most requests for Medical Assistance in Dying (MAiD)? Surprisingly, it's not physical pain but existential distress-the fear of suffering, the loss of dignity, and the struggle to find meaning and purpose as life draws to a close. Yet these very struggles are functional in a process few recognize: the deconstruction of the personal self (the ego), which prepares us for our final and most significant state of being-transcendence. In Early Exits, David Maginley offers a radical reinterpretation of MAiD as an attempt to preserve the ego in the face of this transformation. This is a reflection of our culture's spiritual poverty and reveals MAiD as a medical procedure being used to treat what is, fundamentally, a spiritual condition.Early Exits goes beyond discussions of autonomy, ethics, and dignity to explore the fundamental human experience of dying. Each chapter begins with a real-world case example and ends with practical tools to help readers live-and die-more fully informed. Drawing on decades of research into end-of-life phenomena and over 25 years of experience providing spiritual care to cancer and palliative patients, Maginley illuminates the inner dimensions of dying and how to address the distress that drives MAiD requests. With compelling research, personal stories, and profound spiritual insights, Early Exits reframes dying as a transformative process that leads us beyond grief and despair to a state of grace and growth.Central topics explored: Why existential suffering-not physical pain-is at the heart of requests for assisted death, and how to best address it.How the deconstruction of identity accelerates spiritual growth and calibrates us for transcendence.The importance of addressing both physical and psycho-spiritual needs in palliative care.How MAiD compromises the mystical, expansive states of consciousness experienced by most dying people, regardless of culture or belief.Maginley's insights are shaped not only by decades of experience supporting those facing mortality but also by his own journey as a four-time cancer survivor. Whether you are navigating a terminal diagnosis, supporting a loved one, or providing care as a professional in hospice or palliative settings, this book offers hope and clarity. Early Exits is an essential resource for understanding-and transforming-the most profound and ultimate event in life. It offers a way forward to a better society, a better tomorrow, and a better end to our days.
The Handbook of Sex Differences Volume II Cognitive Variables
The Handbook of Sex Differences is a four-volume reference work assembled and written to assess sex differences in human traits (although findings regarding other species are also included). Based on the authors' highly influential 2008 book Sex Differences, these volumes highlight important new research findings from the last decade and a half alongside earlier findings. Conclusions reached by meta-analyses are also included.This, the work's second volume, summarizes results from thousands of studies pertaining to cognition, broadly defined. Variables related to perceptual and motor skills, emotions, intellectual abilities, and mental disorders are among those examined. Even sex differences in attitudes, beliefs, preferences, and interests are documented in this volume. The seven chapters comprising Volume II are as follows: 9. Perceptual Abilities and Motor Functioning10. Emotional Factors11. Cognitive, Academic, and Intellectual Factors12. Learning, Memory, Knowledge, and Cognitive States13. Self-Assessments and States Of Mind14. Mental Health and Illness15. Attitudes, Beliefs, Interests, and PreferencesThe Handbook of Sex Differences is of importance for any researcher, student, or professional who requires a comprehensive resource on sex differences.
The Handbook of Sex Differences Volume I Basic Biology
The Handbook of Sex Differences is a four-volume reference work assembled and written to assess sex differences in human traits (although findings regarding other species are also included). Based on the authors' highly influential 2008 book Sex Differences, these volumes highlight important new research findings from the last decade and a half alongside earlier findings. Conclusions reached by meta-analyses are also included.In this, the work's first volume, findings from thousands of studies are summarized regarding basic biology. Results having to do with sex ratios at birth and traits involving a wide range of bodily features are reported along with numerous complex aspects of biochemistry, neurology, and physical health. The eight chapters comprising Volume I are as follows: Reproduction, Development, and Morphology Anatomical and Physiological Factors Bodily Fluids, Biochemicals, and Biochemical Receptors The Brain: Structure and Functioning Physical Health and Illness Factors Responses to Physical and Chemical Environmental Factors Responses to Stress and to Pain Prenatal Factors The Handbook of Sex Differences is of significant importance for any researcher, student, or professional who requires a comprehensive resource on sex differences.
Acute renal failure in intensive care
Acute renal failure in intensive care is an independent factor in morbidity and mortality. The prevalence of AKI in patients with hemodynamic instability in the ICU setting can be as high as 50%. The definition is based on the 2012 KDIGO criteria, which combine a clinical parameter represented by the rate of diuresis, and a biological parameter that evaluates the variation in creatinine levels. Prevention starts with identifying subjects at risk, and optimizing systemic and locoregional hemodynamic conditions. The use of products with nephrotoxic potential must be carefully balanced in terms of benefit and risk. The therapeutic approach is essentially symptomatic, with the main aim of preventing worsening of renal damage while awaiting recovery of renal dysfunction.
Code to Cure
The integration of Artificial Intelligence (AI) in drug discovery has significantly transformed healthcare and pharmaceuticals. This book explores the role of AI in transforming traditional processes, integrating biological insights with advanced computational power. It covers foundational concepts like machine learning, symbolic AI, and ethical considerations, and its evolution in various industries, particularly healthcare. AI's contributions include target identification, drug design, virtual screening, and clinical trial optimization. It addresses challenges in traditional methods like high costs, lengthy timelines, and ethical concerns. Advanced AI techniques like machine learning, deep learning, natural language processing, and reinforcement learning are discussed, highlighting their transformative impact on drug discovery's efficiency, accuracy, and accessibility.
Therapeutic education for COPD patients
Chronic obstructive pulmonary disease (COPD) represents a major challenge in terms of patient care, healthcare costs and quality of life. Like any chronic disease, it requires good patient adherence to the necessary care. The aim of this study was to assess the views of general practitioners on therapeutic education for COPD patients. Two questionnaires were used with COPD patients. Physicians were asked about functional signs, positive diagnosis, management and their views on therapeutic education. According to this study, the role of education should be better defined and clearly ensured in a multidisciplinary way by integrating the general practitioner for the benefit of the patient.
Smile Design
The face and its features play a significant role in personality formation and social interactions. Facial aesthetics vary across cultures and are influenced by geographical and cultural factors. A smile symbolizes confidence and attractiveness, and smile design requires interdisciplinary collaboration. Mental health refers to emotional and psychological well-being, which affects thoughts, behaviors, and decision-making, and is influenced by factors such as genetics and life experiences. Smile aesthetics refers to the factors that create a beautiful smile and has gained importance in recent decades. Darwin believed that traits such as facial beauty play a role in mate selection.
Health determinants
One of the diseases on the rise worldwide, caused by the alteration of social determinants in health is diabetes mellitus. To describe the behavior of the social determinants of health associated with type 2 diabetic patients in the period from July 2019 to May 2021. A quantitative-qualitative, descriptive and cross-sectional study was conducted. Women aged 75 to 79 years, white, without schooling, housewives, with a family history of diabetes mellitus, obesity and primary hyperlipoproteinemias as comorbidities predominated. The social determinants of health that had the greatest impact were stress, smoking, inadequate diet and the predominant economic situation classified as high.
Triple-negative breast cancer in young women in western Algeria
Triple-negative breast cancer represents a particular group of breast carcinomas defined immunohistochemically by the absence of hormone receptor expression and the absence of HER2 receptor overexpression. This group of tumors, which have the most unfavorable prognosis, does not currently benefit from any targeted treatment, and the only validated systemic therapy is chemotherapy.This is a retrospective study of the last six years conducted at the Etablissement H繫spitalier Universitaire d'Oran "1er Novembre 1954" (EHUO) between 2017 and 2022 involving 59 young patients with triple-negative invasive breast carcinomas.Pathologically, infiltrating ductal carcinoma was the most predominant type, accounting for 86.4% of cases, with a majority T2 tumor size of 66.1%.Despite advances in treatment and the advent of targeted therapies, breast cancer remains the leading cause of death in women. Current clinical and histological classifications do not allow us to fully establish the prognostic and predictive parameters of response to treatment.
A Novel Acupoint Protocol for Managing Cancer Pain
The improvement in overall survival rates among cancer patients is largely attributed to rapid advancements in cancer treatment modalities. Pain, one of the most common and debilitating symptoms experienced by cancer patients, can significantly impact their quality of life. Fortunately, acupuncture has proven to be a well-established and effective method for alleviating cancer pain, offering patients much-needed relief and an improved quality of life. This 3-minute acupoint protocol is designed to meet the needs of acupuncture practitioners in clinical practice, providing a practical approach to support cancer patients in managing their pain.
