Pathogenetic mechanisms of anxious depression
In this book the author wants to discuss from the clinical and biochemical points of view some aspects of the dynamics of anxious depression under the treatment with serotonergic antidepressants with different mechanisms of action on serotonin reuptake - inhibitor and enhancer. The underlining biochemical and hormonal changes are described. There were investigated the conformational changes of the albumin molecule in patients with anxious depression in dynamics of pharmacotherapy with antidepressant - tianeptine using subnanosecond fluorescence laser spectroscopy with specific fluorescent probe CAPIDAN. There was performed comparative analysis of the conformational changes in patients with anxious and melancholic depression. In anxious depression all amplitudes before treatment were significantly lower than in healthy controls whereas in melancholic depression before the treatment amplitudes were higher as compared with controls. These results point out that that the two types of depression - anxious and melancholic - have different metabolic profile.
Innovative Therapeutic Approaches in Childhood Nephrotic Syndrome
Childhood nephrotic syndrome is a prevalent renal disorder characterized by generalized edema due to hypoalbuminemia from heavy proteinuria. This syndrome can be classified as primary or secondary, with the majority of cases being primary. Current management primarily relies on corticosteroids, but issues such as frequent relapses and steroid dependency necessitate alternative therapies. Recent approaches include the use of levamisole and mycophenolate mofetil, alongside the resurgence of intramuscular ACTH (synacthen) as a treatment option.This book describes the treatment of frequently relapsing steroid-dependent nephrotic syndrome, successfully, with a novel combination of intramuscular synacthen and mycophenolate mofetil. This regimen effectively reduced the required dosage of steroids while minimizing associated adverse effects, particularly psychiatric symptoms. The findings underscore the potential for innovative therapeutic strategies in managing challenging cases of childhood nephrotic syndrome.
What about imported bilharziasis in Tunisia?
Introduction: Although bilharziasis is the second most endemic parasitic disease in the world, it is considered a neglected tropical disease. In Tunisia, only imported cases have been reported since 1984.Objective: to analyze the epidemiological, clinical and parasitological characteristics of bilharziasis cases diagnosed in ENRPT.Methods: Our study was a cross-sectional study conducted over a period of 15 academic years, and included 6051 ENRPT. Each student was thoroughly interviewed and underwent an EPS and EPU before enrolling in a Tunisian institution.Results: Bilharzia was diagnosed in 91 students (1.5%) (76 cases of intestinal bilharzia, 14 cases of urogenital bilharzia and 1 case of a combination of these 2 forms). The sex ratio of patients was 3 and their mean age 24.4 years. Most students were asymptomatic. Association with other digestive parasites was frequent.Conclusion: This study highlights the importance of maintaining systematic surveillance of ENRPT and prompt management.
Medical Jihad USA
CIRCUMCISION OF EITHER SEX IN ANY FORM WHATSOEVER IS NOT ISLAMIC, JUDAIC, NOR CHRISTIAN. IT IS NOT ATTRIBUTABLE IN ANY WAY TO UNITED STATES NATIVE AMERICANS. YET, GENITAL DISMEMBERMENTS HAVE BECOME SECULAR APART FROM THE JERUSALEMIC RELIGIONS. GENITAL DIMEMBERMENTS ARE MOCK-DEATH RITUALS WHERE A PERSON MUST DIE IN ONE FORM TO THEN BE REINCARNATED IN ANOTHER TO THAT WHICH THE SOCIETY DICTATES. AND, WITH THE NECESSARY TAKING OF A BODY PART IT BECOMES A PARTIAL HUMAN SACRIFICE. AS THESE RITUALS EXPAND FROM FAMILIAL PATTERNS TO SOCIAL CUSTOMS TO ACCULTURATION THEY BECOME BOTH CULTURE BAOUND AND/OR CULTURE SPECIFIC SYNDROMES IN A SHARED PSYCHOTIC DISORDER WITH DELUSIONS. GENITAL DISMEMBERMENTS ARE INCESTUOUS. WOMEN WHO TAKE A KNIFE TO THEIR DAUGHTERS, GRANDDAUGHTERS, OR A CLAN'S FEMALE GENITALS ARE AS INCESTUOUS AS FATHERS WHO WHO RAPE THEIR DAUGHTERS OR OTHER FEMALE, OR CLAN'S OTHER FEMALE RELATIVES. SONS AND GRANDSONS ARE INCLUSIVE. A KNIFE BECOMES A PENILE SUBSTITUTE FOR A WOMAN WHO ATTACKS THE GENITALS. GENITAL BLOOD RITUAL MUTILATIONS ARE THEOLOGICALLY BASED IN MENSTRUAL SYMBOLISM WITH REGARDS TO VICTIMS OF BOTH SEXES. INCREMENTAL DEVIATIONS IN SEEMINGLY ETHICAL BEHAVIOR THAT BECOMES UNNOTICABLE AS IT, AND THE TIME, PROGRESSES IS SEEN IN CONDITIONS AS: ETHICAL DRIFT, ETHICAL FADING, AS WELL AS MORAL DISENGEGEMENT THAY DEVOLVE INTO SELECTIVE ETHOS AND SITUATIONAL ETHICS.
The Handbook of Sex Differences Volume IV Identifying Universal Sex Differences
The Handbook of Sex Differences is a four-volume reference work written to assess sex differences, with a primary focus on the human species. Based on the authors' highly influential 2008 book Sex Differences, these volumes highlight important new research findings from the last decade and a half alongside earlier findings.
Microbial Bioprocessing of Agri-food Wastes
This book gives a comprehensive overview of recent advances in the valorization of agri-food waste and discusses the main process conditions needed to overcome the difficulties of using waste as alternative raw materials.
Microbial Bioprocessing of Agri-food Wastes
This book gives a comprehensive overview of recent advances in the valorization of agri-food waste and discusses the main process conditions needed to overcome the difficulties of using waste as alternative raw materials.
The Physiology of Aerobic Capacity in Women
This book questions the dominating concept of the limitation of exercise capacity in women by discussing female physiology from the perspective of respiratory, circulatory, skeletal, body composition, and training adaptations perspectives, based on first-hand research experience.
Maxillofacial Prosthetic Materials
Maxillofacial prosthetics is a specialized dental field focused on rehabilitating patients with facial defects from congenital conditions, traum or tumor removal.They enhance both aesthetics& function, evolving significantly over time with advancements in technology and materials.Historically, the practice dates back to ancient civilizations like Egyptians, who used materials like wood and linen for artificial noses. By 19th century, more systematic approaches emerged, like using rubber&wax, but they had limited durability.The 20th century introduced synthetic materials like PMMA & silicone elastomers, which improved the flexibility&lifelike appearance of prosthesis.Recent advances include modern silicone elastomers with enhanced color stability,3D printing technology for precise customization, composite materials for improved strength, & digital workflow to streamline design&fabrication. Emerging biomaterials&smart materials that respond to environmental stimuli also show promise. Retention of maxillofacial prosthetics is crucial for patient satisfaction. Techniques include using biocompatible adhesives, magnets, custom fitting, effective soft tissue management.
Parasitology for Parents
This book is a handy and necessary resource that reviews the risks of exposure to parasitic illnesses from domestic and international travel with specific relevant information about their transmission, symptoms and treatment. This is Dr. Simon's third "Owners Manual" for parents, grandparents, family members and anyone participating in child care. The series provides information across the spectrum of wellness and health issues for children of all ages, infants to young adults. He has observed that those traveling both domestic and international for school, service or life experience frequently return home ill. They were uninformed about the risks of exposure and illness from parasites acquired by specific travel exposures. This has been an overlooked and neglected area of medicine. On returning home children may be and remain symptom free or have abrupt or acute onset of illness or have symptoms delayed by weeks, months or possibly years after infection started. There may be an unpredictable and variable time between when infection started and symptoms of illness occur. This text is a handy and necessary resource that reviews the risks of exposure to parasitic illnesses from domestic and international travel with specific relevant information about their transmission, symptoms and treatment. The more you learn about parasites, the more it seems like science fiction with different stages and different host at different timings, involving a multistep complex lifecycle. After reading this text you'll never walk barefoot on unpaved grass or soil. You will never eat undercooked, raw, smoked or pickled red or white meat or seafood, or raw aquatic plants. You will not trust FDA regulations allowing a certain level of rodent and insect feces or parts or toxic substances to occur in foods. Yes our foods may have fly eggs, rodent feces and insect parts. They are allowable at certain levels by FDA guidelines that recognizes that these are "natural, unavoidable contaminants" that occur during the growing, processing and packaging of food. The FDA considers certain specified levels of these to be safe and not present a risk for our health. Reading through this text you will find they unfortunately may present a risk for parasitic infections. Yum, yum, chow down!
Functionality of the Elderly at Home in a Situation of Frailty
The growth of the elderly population is a worldwide phenomenon and one of the biggest challenges for public health, especially in developing countries like Brazil. Relevant changes in the morbidity and mortality situation in this country are noticeable and can affect functionality, leading to a loss of autonomy and independence. Thus, evaluation studies that provide information on the specific characteristics of the elderly in terms of their ability to perform the Basic Activities of Daily Living are essential for structuring prevention programs and making therapeutic decisions. This book invites readers in the field of Geriatrics and Gerontology to reflect on the clinical-functional profile of frail elderly people treated in Physiotherapy Programs in the home environment of the public and private sectors in the Northeast of Brazil. There was a greater degree of dependency among the elderly in the private sector compared to the elderly in the public sector. This demonstrates the importance of prolonging and improving the quality of life of the elderly by expanding home-based programs with interdisciplinary care for this age group.
Surgical Pathology of Thyroid Cancer
This publication is dedicated to healthcare professionals, residents, and medical students seeking a practical and up-to-date resource in this subspecialty.Over the past three decades, I have been fortunate to care for countless patients with thyroid disorders, and I have learned invaluable lessons from my colleagues, mentors, and the institutions where I have worked. My goal is to distill this knowledge into a clear and concise text that will serve as a valuable reference for all those interested in thyroid surgery.This guide will cover the most relevant aspects of thyroid pathology, with a particular focus on thyroid cancer. I will present the latest advances in diagnosis and surgical treatment, as well as strategies for preventing and managing complications. To enhance understanding, I have included numerous illustrations and diagrams.I hope that this manual will contribute to the ongoing training of future surgeons and ultimately improve the care of patients. While this work represents my personal perspective based on my experience an thorough review of the literature, I acknowledge the contributions of countless researchers and clinicians who have shaped the field.
Common Drugs in Ophthalmology
The eye is the prominent member of the first sense of the five senses, namely sight. Various types of light-sensitive organs are found in living organisms. The simplest types of eyes can only recognize the presence of surrounding light, while more complex eyes are able to recognize shapes and colors. The human eye has eyelids, eyelashes, conjunctiva, sclera, cornea, pupil, iris, vitreous, lens (eye), aqueous humor, retina and choroid.
Text Book of Forensic Drug and Toxicology
This textbook aims to teach the fundamentals of toxicology and forensic pharmaceuticals to Indian medical undergraduates. It is an extensive work of love that seeks to present the subject in the most methodical and structured manner imaginable. The plan is to mine every last detail for signs of drug abuse and pollutants. All of the headings in the basic Forensic Medicine and Toxicology chapter are clearly divided into subtopics and subheadings.
Salutogenesis in Medical Education
Salutogenesis, a term coined by Israeli-American medical sociologist Aaron Antonovsky in 1979, focuses on the origins of health and the factors that promote it, rather than solely on the causes and treatment of disease. Antonovsky's theory rejects the traditional medical-model dichotomy and emphasizes the importance of personal dispositions in fostering resilience to stressors in daily life. Influenced in public health, healthcare, education, and community development, salutogenesis emphasizes asking the right questions to find relevant answers to health-related questions.The health and wellbeing of college students are not just about individual health but also about the environment they live and learn in. A salutogenic approach to health-promoting focuses on the health potentials inherent in social and institutional settings, rather than the deficit model of disease. Campuses should integrate health into campus culture, share resources, collaborate with instructors, and ensure wide access to resources. Combining traditional pathogenic focus with salutogenic focus is recommended for a sustainable model of health promotion on campuses.
Systemic candidiasis
Invasive mycoses are opportunistic infections, responsible for significant morbidity and mortality among hospitalized patients (40%), which has led to a significant increase in the cost of hospital stays. Among these invasive mycoses, systemic candidiasis is in the forefront, as its frequency is on the increase, to the benefit of other infections. Candida spp accounts for 70% to 90% of all invasive mycosis species.Systemic candidiasis occurs mainly in patients hospitalized on wards housing immunocompromised patients.Risk factors and a colonization index >=0.5 in high-risk wards, especially intensive care and hematology/CAC wards, are predictive of systemic candidiasis. Therapeutic management must be implemented to reduce mortality and avoid the complications associated with these infections.
Emotional Reasoning
Engaging and penetrating, the book represents a groundbreaking perspective that will surprise you at every turn and enhance your understanding of yourself and your place in the cosmic order. The book holds profound implications for neuroscience and artificial intelligence research.
Surgical revascularization of lesions of the left common trunk
A significant lesion of the left coronary common trunk (LCCT) is greater than or equal to 50% of the reference diameter. It is found in 5-7% of pathological coronary angiograms, and is often associated with multi-truncular involvement.The goals of myocardial revascularization in patients with tight CKGR stenosis are to treat angina, improve left ventricular function, prevent myocardial infarction, and improve the quality of life and life expectancy of coronary patients.Advances in interventional cardiology since the advent of active stents, the emergence of safe anti-platelet agents, and the growing experience of operators, have led to a renewed focus on the challenge of percutaneous revascularization of unprotected TCCG with greater ease and safety.The choice of treatment and the strategy for myocardial revascularization depend, on the one hand, on the patient's clinical profile and, on the other, on the angiographic characteristics of the coronary lesions.
Risk management and biosafety
Despite advances in technology, pathological anatomy and cytology (PCA) activities rely on manual methods and are characterized by the handling of infectious risk agents and the extensive use of chemicals, exposing laboratory staff to chemical, biological and physical risks. Within this framework, the aim of our descriptive, observational and prospective study is to determine the various risks in the PCR laboratory and to evaluate biosafety measures in order to implement corrective and preventive actions. Risk management is carried out according to the ISO 31000 risk management process, applying the 5M method to study risks and the 5S method to implement biosafety measures.
Study of the pre-analytical phase
Non-conformities (NC) encountered during the pre-analytical phase could influence the results of analyses and have several negative effects for the patient, such as misdiagnosis and/or delayed treatment.The aim of our work was to detect non-conformities and propose corrective actions to ensure optimal improvement of the pre-analytical phase.We carried out a descriptive observational study in the pathological anatomy and cytology laboratory at Charles Nicolle Hospital in Tunis. The study was carried out over a period of 3 years and 5 months, from January 2020 to May 27, 2023. We developed a questionnaire to assess staff knowledge of the pre-analytical phase. The main causes of NC were assessed using the Ishikawa diagram. Controlling NCs requires staff to be made aware of the importance of reporting any anomaly, so that appropriate corrective action can be taken on an ongoing basis. This action must be seen as a source of improvement and encouragement.
Microbial Bioprocessing of Agri-food Wastes
This book gives a comprehensive overview of recent advances in the valorization of agri-food waste and discusses the main process conditions needed to overcome the difficulties of using waste as alternative raw materials.
Educational Intervention and Algorithms for Cutaneous Carcinoma
Medical and nursing interventions are a framework to achieve knowledge of basal cell carcinoma that affects a given population in order to mitigate the risks of suffering from them or to achieve personal improvement. This leads to the realization of an educational intervention and algorithms in relation to basal cell carcinoma, which includes: sequence of actions, roles of medical and paramedical personnel, preventive and therapeutic methods, diagnostic means and the mode of clinical follow-up.
Retention of permanent anterior teeth
Retained teeth are those that, when they reach the normal time of eruption, remain enclosed within the maxilla or mandible, maintaining the integrity of their physiological pericoronary sac. To characterize the retention of permanent anterior teeth in students between 8 and 19 years of age from schools that attended orthodontic consultation, a cross-sectional descriptive study was carried out. The most affected sex was male. The mean age of the females was 12.1 years and of the males 11.4 years. The canines were the most retained teeth. The vestibular position was the most frequent. Temporal impaction was the main cause. The majority treatment was tooth extraction. Conclusions: In the population studied, retention of permanent anterior teeth predominated in males. The canines were the most affected in the vestibular position. Temporal impaction was the most common cause and the most frequent treatment was tooth extraction.
Factors influencing the transfer of benefits from rehabilitated language
At a time of globalisation, the disappearance of borders and ever-increasing migratory flows since the twentieth century, speech and language therapists are increasingly exposed to bilingual populations with various cognitive and communicative disorders, including aphasia. The wide variability of the resulting disorders and the plurality of bilingualism make bilingual aphasia a particular clinical entity, which cannot be summed up in a single treatment. We therefore sought to identify the factors that might play a part in transferring the therapeutic effects of the rehabilitated language to the non-rehabilitated language. To this end, a bibliometric search led to the selection, reading and qualitative analysis of twenty-six scientific articles. The status of the language treated, the typological proximity of the languages, the nature of the therapy and the nature of the elements included in the therapeutic protocol are the main factors on which it is possible to act in the hope of encouraging this transfer.
Acute mitral insufficiency after percutaneous commissurotomy
Acute rheumatic fever (ARF) is still a common disease in developing countries.In Tunisia, the incidence of RAA has steadily declined. This epidemiological improvement is linked to the national program to combat AAR, long considered a major public health problem.Rheumatic valvulopathies, essentially mitral stenosis, play a major role in our country.Percutaneous mitral commissurotomy is the treatment of choice for pure narrowing (MR). It removes the obstruction with less morbidity and mortality than surgical techniques.However, it can be complicated by acute mitral insufficiency (MI), requiring emergency surgery.Surgery is performed under CEC, with the aorta clamped. The aim of a heart-lung bypass machine is to temporarily replace the pumping and hematosis functions of the heart and lung, respectively. This makes it possible to open the heart chambers and perform surgery on a stopped, bloodless heart.
Management of intracranial subdural empyema
Introduction: Intracranial subdural empyema is a medical-surgical emergency that deserves to be better studied in order to propose standardized management. Methods: Our retrospective study included 53 cases hospitalized in the neurosurgery department of the Tunis Military Hospital over a period of 15 years, whose epidemioclinical, therapeutic and evolutionary data we collected and then analyzed.Results: The mean age of patients was 41.5 years. The majority of cases were treated medico-surgically (90.6%) with broad-spectrum antibiotics (100%), followed by trepanation (84.94%) or craniotomy (5.66%). Initial state of consciousness was identified as a statistically significant prognostic factor (p
Massive hemoptysis
Massive haemoptysis is rare, but a threat due to the risk of asphyxia. The role of thoracic CT angiography in its management remains to be defined. The objectives of our study were to describe the role of thoracic CT angiography in determining the site of bleeding by comparing its data with those of conventional pre-embolisation angiography.Descriptive study of 58 radio-clinical records of patients admitted to the Pneumology Department of Mohamed Taher Ma璽mouri Hospital in Nabeul or Sahloul Hospital in Sousse with massive haemoptysis investigated by CTTA.CT scan revealed recent bleeding in 79.3% of cases. The most frequent cause of bleeding was bronchiectasis. The concordance between CT and angiography in the detection of culprit bronchial systemic arteries (BSA) and non-bronchial systemic arteries (NBSA) was 91.3% and 80% respectively. TDCT had a sensitivity of 84% and a specificity of 62.5% for the detection of culprit ASBs and 80% and 84.6% for the detection of culprit ASNBs. ATDM was more sensitive than angiography in the detection of ASNB.
Human myiasis
Myiasis is a parasitic infestation of mammalian tissues or body cavities by dipteran larvae. It is distributed worldwide but rarely observed in Tunisia. The aim of our work was to describe the epidemiological, clinical and biological characteristics of new cases of human myiasis in Tunisia. Our study is retrospective descriptive, collating four Tunisian cases of myiasis (2018-2022). Diagnosis was made by macroscopic and microscopic study according to Zumpt's criteria. The mean age was 45 years with a sex ratio equal to 1. Travel was not reported in any of our patients. The first two cases were Oestrus ovis nasal myiasis. The third case was a diabetic foot wound myiasis. The larvae identified were Lucilia sericata. The last case was a nosocomial myiasis in the anus of a patient in intensive care. The species identified was Musca domestica. Despite the rarity of cases in Tunisia, positive diagnosis should not be overlooked, especially in at-risk patients with or without travel experience in tropical or subtropical zones.
Prevention and Treatment of Diabetic Heel Syndrome in Patients
Diabetes mellitus (DM) is one of the leading causes of general morbidity, disability and mortality of the population, including those of working age. The social significance of diabetes is determined by its complications. Among infectious and inflammatory diseases in patients with DM2 (DM2), diabetic foot syndrome (DFS) occupies a special place. According to the algorithms of specialized medical care for patients with DM, "Diabetic foot syndrome combines pathological changes in the peripheral nervous system, arterial and miKTocirculatory bed, osteoarticular apparatus of the foot that pose an immediate threat or the development of ulcerative neKTotic processes and gangrene of the foot." DFS requires a comprehensive approach from many specialists, since the lesion of the lower extremities is at the junction of several medical disciplines: therapeutic and surgical. With untimely diagnosis and the absence of correct pharmacotherapy at the very beginning of the complication, DFS progresses rapidly, gangrene of the lower limb develops, which may result in its amputation with Sdfs equent disability of the patient - the most threatening consequence of DFS.
Anatomy, Physiology and Pathology of the Trigeminal and Facial Nerves
One of the most common issues encountered by dentists, neurologists, and otorhinolaryngologists is managing patients with various types of facial pain, collectively known as prosopalgia. These pains frequently stem from pathologies such as trigeminal neuralgia, cranial ganglion disorders, glossopharyngeal neuralgia, and facial sympataglia-which includes conditions like neuralgia of the pterygopalatine ganglion and nasopharyngeal nerve neuralgia.An important factor contributing to trigeminal nerve damage is often the pathology associated with the maxilla. The complexities of pain and disorders in the facial region present significant challenges when it comes to accurately diagnosing diseases related to the trigeminal and facial nerves. Given the overlapping symptoms and diverse etiologies, establishing a precise diagnosis becomes a critical and pressing issue in clinical practice.
How to Do a Systematic Literature Review in Nursing
"Whoever you are, and whatever your background, if you want to know what makes a good systematic review, then get a copy of this third edition by Bettany-Saltikov and McSherry."Dr Ray Samuriwo, Associate Professor in Nursing, School of Health and Social Care, Edinburgh Napier University, UK"This text should be a 'go to' for students from any health care profession, just because it has 'nursing' in its title - it should not be overlooked. This text is an asset to help any healthcare student successfully complete their undergraduate degree."Amanda Blaber, Honorary Fellow College of Paramedics. Retired Senior Lecturer with over 20 years' experience teaching nursing and paramedic students in several Higher Education Institutions"This book is a comprehensive resource to explain the what, when, why, and how to complete a systematic literature review. It is invaluable book for all nurses and health care professionals..."Margaret Spencer, Consultant Occupational Therapist OT360, UKThis new edition of this best-selling book presents a fully revised and updated step-by step guide to doing a literature review for students and professionals in the Nursing, Midwifery, Health and Allied Health professions.How to do a Systematic Literature Review in Nursing takes you through every step of the process of writing a systematic literature review, whether as part of an academic assignment or for publication, from start to finish. Key features of this edition include: A brand new chapter on 'An Introduction to Meta-Analysis', An expanded range of case studies from across the allied health disciplines, Practical tips, templates, questions and answers and key points to help deepen learning.From writing your review question to writing up your review, this practical book is the perfect companion if you are doing your first literature review for study or clinical practice improvement. The text follows a logical ordering, taking readers through all the key steps in a literature review.Written in an easy-to-follow format, the text provides a comprehensive and accessible resource of practical tips, summary's, and templates to work through as part of the review process. It is a must buy for undergraduate or postgraduate Nursing, Midwifery, Health, and Allied Health students and professionals.Josette Bettany-Saltikov is Senior Lecturer in Research Methods at Teesside University, Centre for Rehabilitation and Centre for Public Health, School of Health and Life Sciences, UK. She has taught research methods to nursing students and other allied health care professional students for over 30 years.Robert McSherry is Professor of Nursing and Practice Development, Centre for Ageing and Mental Health, Faculty of Health, Medicine and Society. University of Chester, England, UK.
The Reality of Assisted Dying
"This is a book to be read by all involved in either side of this heated debate."Dr C Fourcade, President of the French Association for Palliative Care, France"This powerful collection of essays brilliantly unpacks the legal, ethical and practical issues around the assisted dying debate."Jonathan Herring, Professor of Law, University of Oxford, UK"This is an essential exploration of the complexities behind the sound bites."Baroness Campbell of Surbiton DBE, UK"A much needed, timely compendium covering the main issues underlying and surrounding Assisted Dying."Robert Twycross, Past Head, WHO Collaborative Centre for Palliative Care, Oxford, UK"Wherever your views lie on ... assisted dying, you should read this book."Dr Matt Morgan, Professor of Intensive Care, Cardiff University, UK, and Curtin University, AustraliaAt a critical moment in the UK debate, this book provides up-to-date reflections from a broad variety of international experts on the profoundly important issues that surround changes in the law in any jurisdiction in connection with assisted dying and considers the realities that surround such changes.The Reality of Assisted Dying covers all the important issues in the debates about assisted suicide and euthanasia. This includes thoughts on the role of the law, discussion of important philosophical and ethical concepts, investigating the various issues that arise in the practice of medicine and palliative care, and scrutinizing concerns about definitions, coercion, consequences and safety.This book: Provides up-to-date data, evidence and reflections from professionals from countries where assisted dying has been legalized;Takes a fresh look at the arguments around legalization of assisted dying;Shows how a change in the law must take account of all those who will be affected, including families and those who will feel compelled to participate by assisting suicides or performing euthanasia;Shows the problems and dangers of embedding assisted dying within healthcare, and explores how alternative socio-legal procedures would improve legitimacy and monitoring for patients and their families.The book is relevant to a variety of intellectual disciplines and to political and social debates both in the UK and internationally, as well as being of interest to general readers and students studying the many relevant subjects, from medicine, to law, sociology, politics, philosophy and ethics.Julian C. Hughes has studied and been a professor of both philosophy and of old age psychiatry. He was an NHS consultant in old age psychiatry and served as deputy chair of the Nuffield Council on Bioethics, UK. His most recent book was Dementia and Ethics Reconsidered, published by Open University Press.Ilora G. Finlay is a Crossbench Peer in the House of Lords, an honorary professor of palliative medicine at Cardiff University, UK, past President of the BMA and the Royal Society of Medicine. A founder director of Living and Dying Well, she co-authored Death by Appointment and led on legislation to encourage the availability of palliative care for all.
Cervical Cancer Prevention
Cervical cancer is a major public health problem worldwide. It is one of the most common cancers, both in terms of incidence and mortality, and ranks first in many developing countries. Cervical infection with oncogenic HPV subtypes is the main aetiological factor in cervical cancer. This factor is necessary for the development of high-risk lesions and cancer. The combination of primary and secondary prevention strategies increases the efficiency of any programme to combat cervical cancer.
Toxoplasmosis in pregnant women
Diagnosis of toxoplasmosis in pregnant women is mandatory and based mainly on serology. The aim of this study was to compare three serological techniques for the detection of anti-toxoplasmic IgG. Our study was carried out between January and April 2023, collecting 53 sera from pregnant women tested by the following techniques: ECLIA (Elecsys(R) Toxo IgG), quantitative ELISA (PlateliaTM Biorad), semi-quantitative ELISA (PlateliaTMTestline) and Blot-line Toxoplasma IgG. The average age of our patients was 29 簣 3.9 years. Serologies were requested during their first pregnancies (72%), in primiparous women (51%) and in 67% during the first trimester. ECLIA and quantitative and semi-quantitative ELISA showed complete agreement (p=1), but IgG titres by ECLIA were higher. On the other hand, almost perfect agreement (P= 0.947) was found when comparing ECLIA and Western Blot. ECLIA appears to be the most sensitive of the techniques studied. In addition, for titres close to the ECLIA positivity threshold, the use of a second confirmatory technique is recommended.
Clinical-Neuropysiological Aspects of Preeclampsia in Pregnant Women
This monograph fully and systematically reflects modern information about the etiology, pathogenesis and diagnosis of gestosis in pregnant women. At the same time, the monograph presents the results of scientific research work carried out to study the clinical, neurological, neurophysiological aspects of gestosis in pregnant women. The work used a comprehensive clinical analysis of the neurological manifestations of gestosis, depending on the severity and dynamics of the pathological process. The authors showed that in the pathogenesis of gestosis, an important role belongs to SVD with the parasympathetic orientation of autonomic reactivity and insufficiency of autonomic support for physical activity.The monograph is intended for general practitioners, neurologists, and specialists dealing with this problem, master's students, clinical residents and students of advanced training courses for doctors.
Basics of Mechanical Ventilation
Mechanical ventilation is a critical tool used in medicine to assist or replace spontaneous breathing when patients experience respiratory failure. The process of using a mechanical ventilator involves complex interactions between human physiology and sophisticated machinery, which must be understood by clinicians to ensure proper patient care. This book, Basics of Mechanical Ventilation: A Step-by-Step Guide provides an accessible yet comprehensive guide to the essential principles, equipment, and management strategies related to mechanical ventilation.Written for medical students, residents, respiratory therapists, and healthcare professionals in intensive care, the book offers an in-depth understanding of the fundamentals of mechanical ventilation, making it a valuable resource for both beginners and those looking to refresh their knowledge.
Photodynamic Therapy After Anti-Glaucoma Surgery
To date, research works are being carried out in the following areas: development and selection of adequate treatment methods; improving the effectiveness of surgical interventions to reduce the frequency and severity of postoperative complications (the use of various drains); improving the prevention of excessive scarring from pathogenetic positions. However, despite all the existing attempts, the long-term results of treatment of NVG still do not satisfy ophthalmic surgeons, due to the high percentage of intra and postoperative complications, including postoperative scarring.In the last decade, in the world, despite the proven effectiveness of the PDT method in the treatment of certain eye diseases, unified methodological approaches to the use of PDT in NVG have not yet been developed. This monograph is devoted to the main aspects of the use of photodynamic therapy in the complex treatment of neovascular glaucoma with experimental and clinical studies. The monograph is intended for ophthalmologists and master's students of medical universities.
Guide to Liver and Gallbladder Health
This comprehensive book delves into liver and gallbladder diseases, offering an in-depth exploration of their diagnosis, management, and modern treatment options. Covering a wide range of conditions-from hepatitis and cirrhosis to gallstones and biliary tract disorders-it integrates the latest research findings with clinical practice insights. Each chapter provides detailed discussions on pathophysiology, diagnostic methodologies, therapeutic approaches, and emerging treatments, ensuring a holistic understanding of these vital organs. Designed for healthcare professionals, students, and anyone interested in hepatobiliary health, this book serves as a vital resource for navigating the complexities of liver and gallbladder diseases.
Persisting Pandemics
Persisting Pandemics explores the history of syphilis and AIDS to provide insights into the limits of biomedicine and our experience with epidemics today. Novel therapies developed for syphilis and AIDS became renowned in the medical field and the broader public sphere as exemplars of biomedical innovations. Public health campaigns based on these spectacular biomedical advances, however, have repeatedly fallen short of their goals to eliminate syphilis and AIDS in the population. The diseases epitomize the power of innovative biomedical therapies for the individual while unveiling limitations of scientific medicine in the domain of public health. The need for a public health approach to address mistrust in science, government indifference, and racial inequalities is relevant for strategies to eliminate COVID-19 today. Persisting Pandemics argues that campaigns to eliminate these diseases have not succeeded because they have not adequately addressed how diseases like AIDS, syphilis, and COVID spread unevenly in populations according to race, ethnicity, and geographic location. Despite the expectation of public health officials that medical advances would render epidemics obsolete, new diseases continue to emerge and spread regardless of efforts to eliminate them. Medical doctor and historian Powel H. Kazanjian concludes that narratives of syphilis, AIDS and COVID, unlike smallpox, do not contain a discrete ending--at least not within the timelines specified by their elimination campaigns. Instead they will be a continued part of our existence.
Screening for Genital Streptococcus B Carriage in the Third Trimester
The last trimester of pregnancy is a period of high rates of genital carriage of germs at risk of maternal and neonatal infection. GBS is the most frequent germ. The objectives were to determine the prevalence and main risk factors for vaginal carriage of streptococcus B in the third trimester of pregnancy, and to establish a strategy for screening for streptococcus B. We also set out the diagnostic and therapeutic means available to detect and treat streptococcus B.A cross-sectional study was carried out at the Monastir maternity hospital, including 330 pregnant women in their third trimester, who were screened from the age of 34 weeks' gestation onwards, and women carrying streptococcus B were given appropriate antibiotic prophylaxis on going into labour. The carriage rate was 8.8%, and was significantly associated with a history of diabetes and living in a rural area. Training and support for healthcare teams in implementing screening protocols and multidisciplinary neonatal management are essential to their success and effectiveness.
Nurses' Knowledge and Attitudes on Breastfeeding Medications
This study aimed to assess the knowledge and attitudes of nurses toward drugs affecting breastfeeding in governmental primary health care (PHC) clinics in the Gaza Strip. A descriptive analytical approach was used to achieve the research objectives. A questionnaire was administered to female nurses working in all 24 PHC clinics under the administration of the Ministry of Health (MOH) in the Gaza Strip. The study sample was selected randomly and consisted of 150 nurses currently employed at governmental PHC clinics in the Gaza Strip. The researcher employed a quantitative, descriptive, and analytical cross-sectional design, with data collection occurring between April and June 2018. Data analysis included frequencies, means, percentages, T-tests, and One-Way ANOVA.The results indicated that half of the participating nurses were aged between 31 and 40 years, and less than half held a bachelor's degree. More than half of the nurses had between 11 and 20 years of experience. The findings also revealed that more than one-third of the nurses were knowledgeable about drugs that affect breastfeeding, and three-quarters of the nurses had positive attitudes toward the use of such drugs.
Misoprostol in Cervical Ripening
Premature rupture of the membranes is a frequent obstetrical condition. It affects 8 to 10% of full-term pregnancies, and its optimal management is controversial. Among the agents used to promote cervical ripening are prostaglandins, of which Dinoprostone is the reference molecule.Material and methods This is a prospective, randomized clinical trial conducted at the maternity and neonatology center of Monastir University Hospital over a period of 1 year (January-December 2017).Including 240 parturients presenting with RPM at term and divided into 2 groups: The "oral route" group: having received 20mcg/ 2h misoprostol solution orally (maximum 6 doses) and the "vaginal route" group: having received 50mcg/ 6h misoprostol vaginally (maximum 4 doses).Conclusion At the end of this study, the use of low-dose misoprostol by VO for cervical ripening at term, with PDER, is as effective as VV in terms of the rate of deliveries within 24 h, while it is slightly ahead at 12 h (44% versus 33%) without the difference being significant.
Brain Health for Learning
In this beautifully-written book, the authors skip across the many bridges that connect neuroscience to education, creating a wonderful resource for educators. They consider all the elements that an understanding of neuroscience can bring to education in a highly accessible manner, focusing on emotions and spiritual meaning as well as more traditional topics like learning and memory. They have produced a tour de force. (Usha Goswami, Director for the Centre for Neuroscience in Education, Professor of Cognitive Developmental Neuroscience and a Fellow of St. John's College, University of Cambridge) This book is singular and a vital service to health, education and labor thinkers, doers and investors. Increased brain capital, which encompasses brain health and brain skills, is vital to educational attainment, upskilling and reskilling. In this book, Staunton and Brennan provide a detailed roadmap for the vital importance of neuroscience to fuel improved education. This area has been oft neglected, but no more. (Harris A. Eyre MD PhD, Lead and Senior Fellow, Neuro-Policy Program, Rice University, USA) This is a hugely useful and insightful text, written in a format which makes a challenging area of discourse accessible. Neuroscience is now the dominant science in education, and it is important to ensure that the synergy between the disciplines is well-founded and robust. This book contributes positively to unravelling the many areas of intersection between neuroscience and education in a rigorous manner. (William H Kitchen, Senior Lecturer Stranmillis University College) This book is an original contribution to the field of educational neuroscience. The authors argue that all adults should pay more attention and become more reflective of their experiences so that they can learn more deliberately and in a focused way. The book addresses the functioning of the brain, the architecture of the brain, neuroplasticity, learning processes and how to develop and maintain a healthy brain throughout life. Learning to learn is about individuals understanding how they learn and thus developing their capacity to learn by harnessing lessons from neuroscience. The book will be useful for learners who are transitioning or returning to education, those training to work with children and young people, and those interested in understanding more about their own learning.
Occupational Stress and Health Effects Among Public Sector Bus Drivers
The book is a comprehensive exploration of occupational stress among KSRTC bus drivers in Kolar, Karnataka. It details the significant health impacts of stress, including physical and mental health degradation among drivers, attributed to the high demands and challenging conditions of their work. Through a meticulous cross-sectional study, it analyzes factors contributing to stress, such as long working hours, urban residency, and lifestyle habits like alcohol consumption and smoking. The book aims to shed light on the prevalence of stress, its correlation with health problems like hypertension and obesity, and the need for targeted interventions and policy amendments to improve working conditions and health outcomes for bus drivers.
Persisting Pandemics
Persisting Pandemics explores the history of syphilis and AIDS to provide insights into the limits of biomedicine and our experience with epidemics today. Novel therapies developed for syphilis and AIDS became renowned in the medical field and the broader public sphere as exemplars of biomedical innovations. Public health campaigns based on these spectacular biomedical advances, however, have repeatedly fallen short of their goals to eliminate syphilis and AIDS in the population. The diseases epitomize the power of innovative biomedical therapies for the individual while unveiling limitations of scientific medicine in the domain of public health. The need for a public health approach to address mistrust in science, government indifference, and racial inequalities is relevant for strategies to eliminate COVID-19 today. Persisting Pandemics argues that campaigns to eliminate these diseases have not succeeded because they have not adequately addressed how diseases like AIDS, syphilis, and COVID spread unevenly in populations according to race, ethnicity, and geographic location. Despite the expectation of public health officials that medical advances would render epidemics obsolete, new diseases continue to emerge and spread regardless of efforts to eliminate them. Medical doctor and historian Powel H. Kazanjian concludes that narratives of syphilis, AIDS and COVID, unlike smallpox, do not contain a discrete ending--at least not within the timelines specified by their elimination campaigns. Instead they will be a continued part of our existence.
Two Strategies in Front of Tobacco Addiction in San Luis, Argentina
This work shows the obtained results during the last fifteen years on the Extension Project "Tobacco smoking: S.O.S. Youth" (National University of San Luis) and the research laboratory of Molecular Fluorescence for the monitoring of toxic metals in tobacco products. During this period, hundreds of Educational Establishments have been visited to realize prevention activities, thousands of students have been surveyed to know the state of affairs tabaquism in San Luis (Argentina), a tens of papers were published and a Doctoral Thesis was defended in the thematic. But the smoking epidemic has not come to an end. New analytical challenges have come hand in hand with new ways of tobacco consumption. So, greater efforts are necessary to highlight the potential health risks of each tobacco product and to prevent our children and young people from starting to smoke.
Study of Scapular Dyskinesia Prevalence in 3 Grip Types for Deadlift
This study investigates the prevalence of scapular dyskinesia in three grip types-hook grip, double overhand grip, and alternate grip-used during deadlifts by amateur weightlifters aged 18-25. Scapular dyskinesia refers to abnormal scapula movement, often caused by muscle imbalance, which can impair shoulder function. Using tests like the Lateral Scapular Slide Test (LSST) and Scapular Dyskinesis Test (SDT), 93 weightlifters from Pune were examined.Results showed that 24.5% of alternate grip users and 21.1% of double overhand grip users experienced scapular dyskinesia, with no significant difference between grip types. The research highlights the importance of understanding grip variations to prevent dysfunction in weightlifters. It suggests increased awareness and further studies on grip-related scapular dyskinesia. The findings emphasize the importance of proper biomechanics in weightlifting to minimize injuries and improve performance.
Reversible acute serous transient reversible pulpitis
Pulpal pathologies constitute the majority of stomatological clinical emergencies and if treated in a timely manner they reduce dental mortality. The general objective was to determine the evolution of the treatment of transient serous acute reversible pulpitis (incipient stage) prolonging the use of eugenol as a pulp sedative up to 96 hours. In the study it was observed that the age group most affected by transient acute serous pulpitis (incipient stage) was 21 to 25 and 26 to 30 years old and the sex most affected was female. The evolution of the treatment was considered favorable when, 96 hours after treatment, the symptoms had completely subsided. Of the total number of patients, the majority had a favorable evolution to the treatment.
