Bone Health Beyond the Scan
While bone density scans (DXA) play a vital role, managing osteoporosis requires a broader perspective. DXA focuses solely on bone mineral density, neglecting crucial factors like bone microarchitecture and quality. These influence fracture risk, especially for those with seemingly normal density (osteopenia). This gap necessitates a multifaceted approach. New diagnostic tools like high-resolution peripheral QCT offer a deeper look at bone structure. Additionally, blood tests for specific markers can shed light on bone turnover and future fracture risk. Integrating these advancements with traditional DXA and a thorough risk factor assessment (age, family history, medications) creates a personalized approach. This allows healthcare professionals to identify individuals at high risk, even with normal bone density, enabling earlier intervention. Beyond diagnosis, a multipronged strategy encompassing nutrition, exercise, and medications is crucial for promoting bone health and preventing fractures. This comprehensive approach paves the way for a healthier future for those susceptible to osteoporosis.
The Mind’s Whisper
"The Mind's Whisper" isn't a fairy tale; it's a guide to understanding the subtle clues your brain might be sending. Worried about forgetfulness or confusion? This book delves into the early signs of cognitive decline, helping you recognize them and navigate the next steps. Learn how to differentiate between normal aging and potential issues, and discover strategies to keep your mind sharp. "The Mind's Whisper" empowers you to become an advocate for your brain health.
Balloon kyphoplasty in spinal fracture surgery
Spinal cord injuries remain a serious problem for all mankind. They not only cause pain, but also significantly limit the social activity of the injured. New types of minimally invasive surgical interventions are being developed to correct and stabilise the spine. One of the promising trends in this area is balloon kyphoplasty. The essence of the method consists in percutaneous insertion of a special balloon into the body of the affected vertebra. The balloon is inserted in a compressed state, and then fluid is injected into it under pressure. The balloon spreads in the vertebral body, providing reduction of post-traumatic compression. The balloon is then removed and the cavity formed is filled with paste-like bone cement. The methacrylate-based bone cement polymerises during the operation, which provides primary stability. The advantages of this method include minimally invasiveness, rapid clinical effect, the use of local anaesthesia, and the possibility to perform the intervention on an outpatient basis. The book will be of interest to orthopaedic traumatologists, rheumatologists, neurologists, neurosurgeons and medical students.
From Structure to Cure
Imagine a tiny, intricate machine responsible for vital functions within your cells. Understanding how these machines, made of proteins, are built (their structure) is the domain of structural biology. This field acts as a bridge between the fundamental building blocks of life and the fight against disease. By visualizing protein structures in atomic detail, scientists can pinpoint how malfunctions arise. Misfolded proteins, for example, are linked to disorders like Alzheimer's. This knowledge allows researchers to design drugs that target specific protein shapes, potentially correcting malfunctions and paving the way for new disease treatments
The Beating Code
"The Beating Code: Advancing Cardiac Modeling with Computational Mechanics" dives into the fascinating world of the human heart, not through a stethoscope, but through the power of computers. This book explores the exciting field of computational mechanics, where simulations are used to understand the heart's complex mechanics. Imagine using computer models to replicate the heart's beating, analyze its stresses and strains, and predict potential problems. "The Beating Code" delves into the sophisticated algorithms and techniques used to create these models, allowing scientists to virtually dissect the heart and study its intricate workings. But this isn't just about creating simulations. The book explores how these models are used in real-world applications. Discover how computational mechanics helps design better heart implants, predict risks associated with heart disease, and even personalize treatment plans for individual patients. "The Beating Code" is a captivating blend of biology, engineering, and computer science. It showcases the power of computational tools in revolutionizing our understanding of the heart and paving the way for a future of personalized cardiac care.
Unmasked Threat
"Unmasked Threat: Head & Neck Cancer" likely isn't a fictional book, but a resource about a serious medical condition. It focuses on head and neck cancers, which can develop anywhere in the head and neck region, including the mouth, throat, voice box, and lymph nodes. The title "Unmasked Threat" suggests the book raises awareness about a cancer that might be overlooked. It could detail risk factors (besides smoking and drinking), symptoms to watch for, and the challenges of treatment, which can impact speech, swallowing, and overall well-being.
Predicting breast cancer treatment outcomes
The monograph presents a review of modern ideas about the pathogenesis of breast cancer, including molecular risk factors of aggressive tumour growth in the breast and disorders occurring in the genetic apparatus of the cell. The main problems of individualisation of treatment are considered, the basics of personalised medicine and its importance in treatment are given. The authors of the monograph to improve the effectiveness of treatment of cancer patients with breast cancer before the start of treatment offer to carry out genetic testing, i.e. to identify genetic factors that determine or determine the response of the organism to the action of drugs.
Collection of MCQs and clinical cases in medical oncology
A collection of multiple-choice questions and clinical cases for medical oncology students and residents, with answer keys, covering a range of basic and therapeutic medical oncology fields to help medical students and residents practice preparing multiple-choice questions and also some clinical cases to facilitate understanding and management of the cancer patient.
Digital Polymerase Chain Reaction (dPCR)
This book, "Digital Polymerase Chain Reaction (dPCR): Advances and Applications in Contemporary Laboratory Practice," explores the principles, fundamentals, advantages, and applications of dPCR in research and clinical practice. The book is divided into seven chapters, with the first chapter providing an introduction to dPCR and its significance in modern molecular biology. The second chapter delves into the fundamentals of dPCR, while the third chapter explores the advantages of dPCR over conventional PCR techniques. The fourth chapter discusses the diverse applications of dPCR in research and clinical practice, and the fifth chapter examines the latest advances and innovations in dPCR platforms and methodologies. The sixth chapter speculates on future directions and opportunities in dPCR research and applications, and the final chapter provides a comprehensive summary of the book's key findings, implications, and insights. The book is intended to provide researchers, clinicians, and students with a comprehensive resource that not only elucidates the principles and applications of dPCR but also inspires further exploration and innovation in this dynamic field.
Islamic Medicine
In the centre of naturopathic and herbal medicine is a living healthcare tradition called Tibb. Prophetic medicine provided the foundation, and over time integrated elements from Egypt, India, China and classical Greece. Tibb is an Arabic word, which in difference placed has been referred to as Arabic, Greco-Arab, Hikmah, Unani, Islamic and Sufi medicine. This is the first systematic study of Tibb - Islamic Medicine - as a living tradition, by a practising Hakim, to be published in the English language. Originally published in 1986, this is the 6th edition expanded with practical resources. This book introduces the reader to Tibb as a holistic paradigm of health. It explains the history and philosophy of Islamic Medicine, as well as its psychological and physiological concepts. The book discusses Tibb's theory of causes, diagnostic methods and offerings for preventative healthcare.
Gamma-Delta T Cells
Our bodies need protection against pathogen invasion and for that we employ our immune system which is armed with an arsenal of cells and proteins. This immune network is destined to eliminate microbes and substances determined to pose significant threat to the normal functioning of our bodies by confronting viruses, bacteria, toxins, fungi and parasites, or even by battling tumoral cells. So, the immune system develops mechanisms at least equal in effectiveness and ingenuity to the infectious or transforming threat. At the same time, the maintenance of homeostasis and prevention of self-destruction is a very important function managed also by the immune system via tolerance mechanisms. This orchestration and customisation of the immune system aim in securing our best survival1,2. The network of immune cells is usually divided into the innate and adaptive leg (figure I.1). The first harbours ready-for-action cells (e.g. monocytes, neutrophils, natural killer cells) and the second highly specialised agents (T and B lymphocytes). Even though separated in categories the cross talks and cooperation between the two legs are constant and crucial. T and B lymphocytes recognise and bind a broad range of antigens through the highly diverse antigen receptors on their surface (T-cell receptor for T lymphocytes and B-cell receptor for B lymphocytes) and confer the essential aspect of immunological memory1. In the T spectrum, there are unconventional cases of more rapid responders such as mucosal-associated invariant T (MAIT) cells (αβ), natural killer T (NKT) cells (αβ) or the γδ T cells3. The focus of this work is on the human γδ T cells and especially the Vγ9Vδ2 T cell population which provide unique functional specialisation.
Teen Troubles & Treatment
South Africa has made incredible strides in fighting HIV/AIDS, but a hidden hurdle remains. Teenagers, often diagnosed during adolescence, face unique challenges sticking to their medication (ART). This is because adolescence coincides with a critical brain development stage, particularly in areas responsible for planning and organization - skills crucial for taking medication consistently. This "executive dysfunction" can lead to missed doses and jeopardize the effectiveness of their treatment. Understanding this link between brain development and adherence is vital for improving HIV treatment outcomes for young South Africans.
Beyond the Molecule
"Beyond the Molecule" dives deeper than just the structure of biomolecules. It explores the concept of free energy, a hidden force guiding their shape and function. This understanding unlocks a new approach to drug discovery. By understanding how free energy influences biomolecules, researchers can design more effective medications to target diseases at their core. This book is for scientists, students, and anyone curious about the future of medicine and the unseen forces that govern life's building blocks.
Unveiling the Mystery of Phenotypic Heterogeneity in Simplex Autism
Autism Spectrum Disorder (ASD) presents a complex puzzle. While recent genetic advances have identified genes linked to ASD, the vast variation in symptoms (phenotypic heterogeneity) among individuals remains a mystery. This is particularly puzzling in simplex autism, where only one child in a family is affected. Despite a seemingly simpler genetic background, these cases still display a surprising range of symptoms. This work delves into this very mystery. By analyzing genetic data and phenotypic traits in simplex autism cohorts, researchers aim to uncover the link between specific gene mutations and the severity of ASD symptoms. This in-depth exploration has the potential to shed light on why individuals with similar genetic mutations can exhibit such diverse characteristics. The findings could pave the way for a deeper understanding of the underlying causes of ASD heterogeneity and ultimately lead to more personalized treatment approaches
Halothane & Muscle Dysfunction
Anesthesia keeps us comfortable during surgery, but what happens at the cellular level? " Halothane & Muscle Dysfunction " delves into the fascinating science behind how certain anesthetics, like halothane, impact our cellular machinery. This book explores how halothane disrupts the delicate process of cellular respiration, the way cells generate energy. You'll discover the mechanisms behind this disruption and its potential effects on various tissues. The book goes beyond halothane, examining the broader impact of different anesthetics on cellular respiration. We'll explore the ongoing research to develop safer and more targeted anesthetics with minimal cellular side effects. " Halothane & Muscle Dysfunction " bridges the gap between medicine and cellular biology, offering a captivating glimpse into the unseen world within us.
Heart’s Rhythm
Heart's Rhythm: Electrical to Mechanical Maestro The rhythmic thump of your heart, a constant presence from your very first breath, is a captivating testament to the body's intricate workings. But what orchestrates this seemingly effortless pulse? The answer lies in a captivating dance between electrical impulses and muscular contractions, a dazzling display of how electrical signals translate into the mechanical marvel of a beating heart. At the helm of this electrical ballet stands the sinoatrial node (SA node), a tiny cluster of specialized cells nestled within the right atrium of the heart. Often referred to as the body's natural pacemaker, the SA node acts as the conductor, generating electrical impulses rhythmically and independently. These impulses, like ripples on a pond, spread outwards, triggering a wave of depolarization across the atria, the heart's upper chambers. Depolarization signifies a critical shift in the electrical charge across the cell membrane of these atrial muscle cells. This influx of ions flips the polarity, causing the previously relaxed muscle cells to contract. As a result, the atria squeeze, efficiently propelling blood into the ventricles below, the heart's powerful pumping chambers.
Beyond Inherited
Personalized medicine promises a future where treatments are tailored to your unique genetic makeup. But what if the key doesn't lie solely in your inherited genes? "Beyond Inherited: Personalized Medicine" explores the fascinating world of de novo mutations - genetic changes that arise spontaneously, not passed down from parents. This book goes beyond the familiar territory of inherited conditions. We'll delve into the groundbreaking research on de novo mutations and their impact on human health. Discover how these unique mutations can influence disease risk, response to medications, and even how your body functions. "Beyond Inherited" isn't just about scientific discovery; it's about a revolution in healthcare. By understanding de novo mutations, we can create a new level of personalized medicine. Imagine treatments designed specifically for your unique genetic makeup, maximizing effectiveness and minimizing side effects. This book is a beacon of hope, offering a glimpse into a future where personalized medicine lives up to its promise. It empowers patients to become active participants in their own healthcare journey, with a deeper understanding of their individual genetic landscape.
Beyond the Mask
The African narrative on autism is about to change. "Beyond the Mask: Autism in Africa" sheds light on the experiences of individuals with Autism Spectrum Disorder (ASD) across the continent. This groundbreaking book challenges the misconception of ASD being a Western phenomenon. "Beyond the Mask" explores the unique cultural understanding and presentation of ASD in Africa. Delve into the challenges faced by families and individuals, often due to limited diagnosis, resources, and societal awareness. Yet, the book also celebrates the resilience and strength of African communities in supporting their autistic loved ones. This book is more than just raising awareness. It empowers families, educators, and healthcare professionals with practical guidance and resources. "Beyond the Mask" calls for a more inclusive Africa that embraces neurodiversity and unlocks the full potential of autistic individuals. Join us on this journey to see autism in Africa, beyond the mask.
Mind Control Master
Toxoplasmosis, a widespread parasitic infection, affects up to a third of the world's population. Caused by the Toxoplasma gondii parasite, it has a unique two-stage life cycle. Cats, the definitive hosts, harbor the sexual stage, shedding infectious oocysts in their feces. These oocysts can contaminate soil and be ingested by warm-blooded animals, including humans, initiating the asexual stage. In humans, a healthy immune system keeps the parasite dormant, often with no symptoms. However, toxoplasmosis can be serious for pregnant women and those with weakened immunity. It can cause miscarriage, birth defects, and eye problems. The parasite's ability to manipulate host behavior in rodents, possibly increasing their predation risk by cats, raises concerns about similar effects in humans. Understanding its global spread and complex life cycle is crucial for preventing its potentially devastating impact.
Shireen@123
AR in Surgery: Planning the Future The operating room has long been a realm of meticulous precision and unwavering focus. But the future of surgery is being reshaped by a groundbreaking technology - Augmented Reality (AR). AR overlays digital information onto the real world, offering surgeons a revolutionary way to visualize anatomy, plan procedures, and ultimately improve patient outcomes. Beyond the Scalpel: The Promise of AR Traditional surgery relies heavily on surgeons' mental visualization of a patient's anatomy based on pre-operative scans. AR disrupts this paradigm by introducing a new layer of information directly into the surgeon's field of view. This offers several advantages: - Enhanced Visualization: AR overlays 3D models of the patient's anatomy, including bones, blood vessels, and nerves, directly onto the surgical site. This allows surgeons to see crucial structures hidden beneath the surface, improving their spatial awareness and reducing the risk of accidental injury. - Improved Precision: AR can guide surgeons with real-time data during complex procedures. Imagine virtual annotations highlighting critical structures, or projected lines indicating optimal incision points. This level of precision can lead to minimally invasive procedures, faster recovery times for patients. - Enhanced Training and Collaboration: AR can revolutionize surgical training by creating immersive simulations. Trainees can practice complex procedures in a safe, virtual environment before operating on real patients. Additionally, AR allows for remote collaboration with specialists during surgery, facilitating real-time guidance and expertise sharing.
Islet Transplants
For millions living with type 1 diabetes (T1D), the dream of a cure feels distant. Daily injections are a constant reminder of the disease. However, islet transplants offer a glimmer of hope, a potential bridge towards a T1D cure. These procedures involve transplanting healthy islet cells, the body's natural insulin producers, into a recipient with T1D. Islet transplants hold immense promise. Imagine a future where the body regulates blood sugar naturally, eliminating the need for injections and the constant monitoring that comes with T1D. While challenges like donor availability and rejection remain, ongoing research is making strides. Islet transplants may not be a complete cure yet, but they represent a significant step towards a future free from the burden of T1D
ADHD Diagnosis
While consistency is vital in managing ADHD, it's not the only piece of the puzzle. Children with ADHD often struggle with core executive functioning skills, impacting focus, planning, and self-control. These challenges go beyond simply needing a set routine. Think of it like this: imagine a child with a toolbox missing key tools. Consistency provides structure, but they still need help using the tools effectively. Here's where additional support comes in. Techniques like visual schedules, breaking down tasks, and fidget toys can empower the child. Occupational therapy can improve focus and motor skills. Medication, when appropriate, can offer a boost in attention. By combining consistent routines with targeted support for underlying challenges, we can empower children with ADHD to thrive.
Flexible PVDF Probes for Adaptive Ultrasound
Traditional ultrasound probes are rigid, limiting their ability to image complex body structures. Enter PVDF (polyvinylidene fluoride) probes - the future of adaptive ultrasound. These innovative probes are micromachined from a special plastic that converts pressure into electrical signals. This flexibility allows them to bend and conform to the body's contours. The advantages are numerous. PVDF probes provide superior contact with uneven surfaces, resulting in sharper, more detailed images. They can navigate tight spaces and reach organs previously inaccessible. Additionally, their flexibility allows for consistent pressure application during scans, reducing operator variability and improving image quality. This technology holds immense potential. Imagine a comfortable, wearable PVDF patch for continuous organ monitoring or a probe that effortlessly curves around limbs for better bone visualization. Flexible PVDF probes promise a future of adaptive ultrasound imaging, leading to more accurate diagnoses and personalized patient care
Cells Connect
The intricate dance of life relies on constant communication between cells. But how do these microscopic factories exchange cargo or fuse entirely? Enter SNARE proteins, the cellular matchmakers orchestrating membrane fusion. These fascinating molecules reside on both vesicles (transport packages) and target membranes. SNAREs come in v-SNARE and t-SNARE flavors, each with a specific docking site. Like puzzle pieces, they precisely bind, forming a tight complex that pulls membranes into close proximity. This intricate choreography isn't spontaneous. Specific SNARE combinations ensure only the right membranes fuse. Imagine a delivery truck needing the exact key to unlock the warehouse door. This precision ensures targeted delivery and prevents unwanted mergers. Understanding SNARE secrets unlocks a treasure trove of possibilities. From engineering targeted drug delivery to unraveling the mysteries of fertilization, these fascinating proteins hold the key to manipulating cellular communication at its core.
Stop the Depression Crisis
Depression isn't just a personal struggle; it's a global challenge impacting an estimated 280 million people. This mental health condition significantly disrupts daily life, affecting work, relationships, and physical health. The causes are multifaceted, ranging from social and economic stressors to biological factors. The burden falls disproportionately on women and certain age groups. Despite effective treatments like therapy and medication, access remains a major hurdle, especially in developing countries. Stigma surrounding mental illness further deters many from seeking help. Addressing this global challenge requires a two-pronged approach: increasing access to quality mental healthcare and dismantling the stigma associated with depression. With these steps, we can create a world where everyone has the support needed to overcome depression and thrive
ICU
The ICU isn't just about saving lives; it's about sustaining families. Witnessing a loved one in critical condition can be overwhelming. ICU staff recognizes this, extending their support beyond the bedside. Social workers become anchors, navigating the complexities of healthcare decisions and discharge planning. Chaplains offer emotional and spiritual solace to families grappling with fear and uncertainty. Patient family support specialists provide a listening ear and practical resources, helping families navigate the logistical hurdles of long hospital stays. This holistic approach acknowledges that a patient's well-being is intricately linked to their family's strength. By supporting families, the ICU fosters resilience, allowing them to be a source of strength for their loved one on the road to recovery.
Genetic engineering
This study analyzes the therapeutic purpose of genetic manipulation in human embryos under the aegis of the principle of human dignity, the fundamental right to life, freedom of scientific expression, free family planning and health. Furthermore, this discussion is also concerned with portraying the role of the judiciary in cases in which the legitimacy of new concepts regarding the application of principles and rights to specific cases is discussed.
Diabetes 2023. from Folklore to Biotechnology
In the middle of the night on August 21, 1978 a 27-year old biochemist called Dave Goeddel used a recently developed revolutionary method to join two pieces of protein in a test tube to create modern insulin thus ending the need to sacrifice millions of animals every year to supply insulin for treating diabetes as had been the practice since the discovery of insulin by Frederick Banting and his team in 1921.Goeddel belongs to a new breed of scientists who had the courage and ingenuity to pioneer a method which bypassed the natural methods of reproduction which had evolved over millions of years. Modern insulin, the first medical product made by this method launched the biotechnology revolution and today's multibillion dollar biotechnology industry which manufactures a host of products ranging from antibiotics to vaccines for immunisation against various infections including Covid-19.
Innate Defense
Our body's first line of defense, the innate immune system, is a complex army of cells and processes working tirelessly. These unsung heroes include: - Physical Barriers: Skin and mucous membranes form a formidable frontline, like a castle wall, repelling invaders. - Phagocytes: These white blood cell warriors, like macrophages and neutrophils, engulf and destroy foreign microbes, acting as the system's janitors. - Chemical Warfare: Tears, saliva, and stomach acid contain antimicrobial substances that neutralize or kill pathogens before they can infiltrate. - Inflammation Brigade: When a breach occurs, immune cells trigger redness, swelling, and heat, isolating the threat and attracting reinforcements. Innate immunity acts swiftly and broadly, providing a vital first response while the adaptive immune system gears up for a more targeted attack. This intricate teamwork safeguards our health constantly
Rhizarthrosis of the Thumb
Surgical treatment of rhizarthrosis remains a matter of debate, with the choice essentially between total trapezectomy techniques with or without suspension and interposition tendinoplasty, and TM prostheses, as shown by several publications. The majority of authors agree that trapezectomy-interposition-ligamentoplasty techniques give better results, or at least results identical to those of arthroplasty, with fewer disadvantages. This technique is designed to achieve the precise objectives of indolence, stability, mobility and strength of the thumb. Use of the Abductor Pollicis Longus hemi-tendon reduces the destabilizing action of this tendon on the first metacarpal. The aim is to promote abduction and reduce ascent of the first metacarpal on the carpus, as shown by the work of Zancolli et al.
The Pain
In the last 50 years, neuroscience has made significant advances in understanding neural processes. The creation and development of various methods of examining the function of the nervous system has given neuroscientists many opportunities to investigate and answer questions such as how changes in the brain lead to disease or what makes the human brain unique.Understanding the dynamic complexity of the nervous system is a research challenge in the world of science. The analysis of the nervous system includes several levels from the cellular and molecular domain to the systemic, computational, and cognitive examination of the brain. The specific topics that form the main focus of neuroscience research will change over time, and data and results will be added to with increasing knowledge and the creation of new methods and technologies.In recent decades, neuroscientists have made many discoveries about neurons, the brain, and the central nervous system. The ancient Egyptians believed that the seat of intelligence was in the heart. Because of this belief, after the embalming process, they removed the brain from the body and left the heart in place.
Diseases of the External and Middle Ear
This monograph includes various types of ear pathology, united by the common localization of pathological changes in the area of the external auditory canal, the auricle and the structures of the middle ear.Risk factors for the development of external otitis: eczema (allergy), cerumen, congenital narrowness of the ear canals, chronic otitis media, immunodeficiency conditions, diabetes, wearing hearing aids, players. The most typical manifestations of inflammation of the outer ear are pain on palpation of the auricle or tragus, spontaneous pain in the ear, itching in the ear (with fungal infection, eczema), swelling and hyperemia of the skin of the ear, enlarged lymph nodes in the ear area, a feeling of congestion in it, discharge from ear, hearing loss is usually minor. Inflammatory diseases of the outer and middle ear are still very common in otorhinolaryngological practice, despite a fairly large arsenal of modern treatment methods. This is due to the polyethological nature of these diseases, the irrational use of medicines, primarily antibiotics, as well as adverse environmental factors.
Understanding HIV/AIDS
HIV, also referred to as the human immunodeficiency virus, infects and destroys the immune system cells, making it difficult to fight off other diseases. When HIV has significantly compromised your immune system, it can lead to acquired immunodeficiency syndrome (AIDS).AIDS is the last and most critical stage of an HIV infection. Individuals suffering from AIDS have very low counts of certain white blood cells and severely compromised immune systems. They may have additional illnesses that indicate the development of AIDS. Without therapy, HIV infections progress to AIDS in about 10 years.
Heart
Heart attacks, a leading cause of death globally, may hold less fear in the future thanks to advancements in technology. Researchers are exploring exciting possibilities for repairing and regenerating damaged heart muscle after an attack. One approach utilizes messenger RNA (mRNA) technology, similar to the mRNA vaccines. Injected directly into the injured area, these mRNA strands instruct surrounding cells to produce proteins that promote healing and growth. Studies in mice have shown remarkable recovery of heart function after this treatment. Another area of exploration involves gene editing with CRISPR. This powerful tool could potentially modify genes within heart cells, enhancing their ability to repair themselves or even convert other cell types into functional heart muscle. These technologies are still in early stages, requiring further testing and refinement before human trials. However, the potential for a minimally invasive, tech-driven approach to heart attack repair is a beacon of hope. It could significantly improve patient outcomes, reduce reliance on procedures like bypass surgery, and offer a new lease on life for those affected by heart attacks.
Neuro Care Revolution
As lifespans increase, so too does the prevalence of age-related neurodegenerative diseases like Alzheimer's and Parkinson's. These conditions, characterized by the progressive decline of brain function, pose a significant threat to individual and societal well-being. The aging brain undergoes a complex dance of cellular damage and repair. The accumulation of protein clumps, like amyloid plaques in Alzheimer's, disrupts communication between neurons, leading to memory loss, cognitive decline, and movement disorders. This growing threat demands a multi-pronged approach. Research is accelerating, aiming to understand the underlying causes of neurodegeneration and develop effective treatments. Early detection and preventative measures, including healthy lifestyle choices, are crucial. Investing in brain health research and promoting healthy aging strategies are key to mitigating this growing threat. By working together, we can ensure a future where aging minds remain sharp and vibrant.
Miscarriage Prevention
Miscarriage Prevention & Its Impact on Preterm Birth is a scholarly effort documenting innovative reproductive care concepts and proposing a more comprehensive obstetrical care protocol. Challenges such as polycystic ovary syndrome (PCOS) and preterm delivery are discussed in detail.The theme of Miscarriage Prevention & Its Impact on Preterm Birth is a reproductive care journey with these major divisions.A Well-Traveled Road to Recurrent Pregnancy LossA Less-Traveled Road to Miscarriage PreventionApproaching Our Destination of OpportunityModifying Outcome and Reaching Our Destination Safely
Epidemiological profile of dyslexic patients in ABC Paulista - Brazil
Dyslexia is a disorder that causes difficulty in reading and also compromises written language. Studies show that dyslexia has genetic characteristics, with heredity in between 23 and 65% of cases. Dyslexia affects between 5-17% of schoolchildren. The first description of this condition dates back to 1896 and was described by the English neurologist Pringle Morgan, who named it congenital verbal blindness. Since then, various theories have been put forward about the origin of this disorder, the most widely accepted today being the neurobiological cause. The Brazilian Dyslexia Association (ABD), as well as the International Dyslexia Association (IDA) and the National Institute of Child Health and Human Development (NICHD), define dyslexia as follows: "a specific learning disorder, of neurobiological origin, characterized by difficulties in accurate and/or fluent word recognition, decoding skills and spelling. These difficulties usually result from a deficit in the phonological component of language and are unexpected in relation to age and other cognitive abilities."
Humanistic assistance to mothers during fetal and neonatal death
Project for the conclusion of the undergraduate course in Nursing at the Centro Universit獺rio S瓊o Camilo. This is a qualitative integrative review of the care provided by the nursing team to mothers at the fateful moment of the death of a child and the grief they experience. To gain a better understanding of the care provided to this public in Brazil. Authors: Adevania Maria de Barros Freire Flavia Seabra Renata Noguchi Elisb瓊o Thais de Aquino Antunes.
Herbal Healing
This abstract explores the profound and ongoing role of plant compounds, orphytochemicals, in shaping human health and well-being. Throughout history, humanity has relied upon the rich diversity of phytochemicals found in plants forsustenance, medicine, and vitality. Modern scientific research has unveiled thetherapeutic potential of these compounds, paving the way for innovativeapproaches to healthcare. From antioxidants and anti-inflammatories to cancer-fighting agents and neuroprotective wonders, plant compounds continue tocaptivate the healthcare world. Their versatility is showcased in clinicalapplications spanning cardiovascular health, immune support, mental wellness, andmore. Integration with conventional medicine and personalized healthcareapproaches further underscores their relevance. Yet, the journey towardsharnessing plant compounds is not without challenges. Issues of regulation, safety, and misinformation pose hurdles. Ethical and sustainable practices are paramountto preserving nature's offerings. The holistic approach to herbal healing, acknowledging the interconnectedness of body, mind, and spirit, emerges as aguiding principle.
Surgical Approaches To Facial Skeleton
There are various reasons for exposing the facial skeleton. Treatment of different fractures, management of paranasal sinus disease, esthetic procedures, osteotomies, facial deformities and reconstructive procedures require approaches to the facial framework. The choice is usually made on the basis of the surgeon's training, experience and bias. The book doesn't advocate one approach over another, although the advantages and disadvantages of each approach will be listed. The purpose of this book is to enlighten the anatomical and technical aspects of most commonly used surgical approaches to the facial skeleton. It also enlighten about the various instruments used during incision, retraction, manipulation of the soft tissues, reduction, fixation and closure. Various approaches and their alternatives are also discussed. The approaches presented in this book will allow the surgeon complete access to the craniofacial skeleton for whatever skeletal procedure is being performed.
Immunological and Molecular Study of Human Metapneumovirus
The aim of the book is to identify the role of human Metapneumovirus in children with respiratory infections. This study was conducted on 100 patients with respiratory tract infections who were admitted to Al Zahra Teaching Hospital and the AL-Forat AL-Awsat Teaching Hospital in Najaf Governorate during the period November 2020 to February 2021, Nasopharyngeal swabs were collected from patients to molecular diagnosis of human metapneumovirus by Real-Time-PCR, serum specimens were also collected from patients and control to measure the concentration of both TNF-α and IL-10 using ELISA. The results obtained from nasopharyngeal samples were amplified by RT-PCR for the diagnosis of hMPV the percentage of samples were positive for the virus (53%) from (100) specimens.
Urinary Lithiasis in Children
Urinary lithiasis in children poses a serious problem, affecting the functional future of the kidney. Etiological investigation must be exhaustive in order to avoid recurrence and prevent impairment of renal function. A retrospective study of 168 observations of urinary lithiasis collected over 8 years. All stones were analyzed by infrared spectrophotometry.The annual average was 21 cases, the most frequent symptomatology being urinary tract infection. The stone was located in the upper tract in 65% of cases. Lithiasis was associated with a metabolic etiology in 17% of cases, and with malformative uropathy in 20%. Treatment consisted of open surgery in 96% of cases. Calculi were pure in 36% of cases. Whewellite was present in 72% and predominant in 38% of stones.The therapeutic indication depends essentially on the size and location of the stones. Extracorporeal lithotripsy can be considered as 1st-line treatment, or in association with percutaneous nephrolithotomy and ureteroscopy. Surgery is still indicated when minimally invasive techniques fail.
Must We All Die?
Alaska Natives have struggled with the 'white plague' of tuberculosis for centuries. At last, physician and historian Robert Fortuine brings their story to light. He provides a comprehensive account of tuberculosis from its earliest occurrence in prehistory through the latest outbreaks, made more threatening by HIV/AIDS. Fortuine describes the courage and self-sacrifice of itinerant nurses who endured challenging and often dangerous conditions, as well as the efforts of doctors who fought cuts in funding as valiantly as they battled for the lives of their patients. Fortuine chronicles the removal of tuberculosis victims, many of them children, from their families and villages to hospitals in the Lower 48 states. He describes treatments, medical advances, and day-to-day life for the nurses, physicians, missionaries and teachers who worked to stem the tide that killed and disabled thousands. The struggle against tuberculosis in Alaska is a story of triumph against untold suffering and crippling odds, but it is also a cautionary tale, as villages experience the re-emergence of an increasingly resistant disease in the twenty-first century. Must We All Die? is a timely and encyclopedic contribution to the history of medicine. Historians and health care professionals will hail the volume as a classic, a tribute to those who fought tuberculosis and to the Alaska Natives who endured a cruel disease that destroyed families and ravaged villages.
150 Years of Nevada Medicine and more (Second Edition)
ORGANIZATION: 150 YEARS OF NEVADA MEDICINEThe volume, number, and year of each issue of Greasewood Tablettes is at the end of the article, and the author is listed at the beginning. Initially only articles from Greasewood Tablettes were to be included in 150 Years of Nevada Medicine, but to be complete we were compelled to include additional information. Also, articles not relevant to Nevada were eliminated.Accordingly this endeavor will be a collection of Greasewood Tablettes' articles grouped into eleven chapters: Medical Education, Medical Disciplines/Specialties, Hospitals, Frontier Military Medicine, Native American Medicine, Chinese Medicine, Diseases, The Hood Dynasty, 19th-Century Doctors, 20th-Century Doctors, and The Unusual.The essays are unchanged from their original publication in Greasewood Tablettes except for three considerations. First, we deleted repeat information, although some repetition is necessary to maintain the integrity of the original essay. Second, the titles and some essays were edited to conform to a uniform design, but they still reflect the original content and subject matter. Third, new information is added to increase the scope and completeness of 150 YEARS OF NEVADA MEDICINE.
Chronic shoulder instability in young people
Recurrent anterior shoulder instability (RASI) is a chronic symptomatology that occurs after anteromedial dislocation, or after repeated subluxations or purely painful episodes. It manifests itself in the form of uncomfortable apprehension of subluxation, or even dislocation, when the patient carries the arm in abduction and external rotation. It should be noted that anterior shoulder instability is not only clinically manifested by anteromedial dislocation, but that there are also frustrated clinical forms.The bone block described in 1954 by Latarjet was modified by Patte in 1980 under the name of triple locking (bone, muscle and capsular).This technique gives good functional results: 92% of patients are satisfied.
Bone fluorosis in Tunisia
Bone fluorosis results from the accumulation of fluorine in bone tissue due to prolonged exposure to high doses, mainly through ingestion of contaminated water. Initially asymptomatic, it can manifest itself in adulthood with serious neurological complications.In our study of 18 patients, fluorosis was diagnosed by epidemiological and radiological data, due to the unavailability of biological data. Symptoms were often severe, but stabilization of signs was observed in the majority of cases. Sources of exposure included hydro-telluric intoxication and two cases of occupational intoxication. Improving the water distribution network could help limit fluorosis. Worldwide, studies are mapping endemic areas and exploring genetic predispositions.Although cases of bone fluorosis are declining, our understanding of the disease remains crucial, as new aspects are emerging and arousing the interest of researchers.
Hepatitis E virus, history and epidemiological trends
The hepatitis virus (HEV), the fifth viral hepatitis virus identified in 1983, is a small, naked ribonucleic acid virus with 8 genotypes distributed worldwide. In recent years, a better understanding of the natural history of HEV infection has clarified its epidemiology. Hepatitis E is the world's leading cause of acute non-A viral hepatitis of fecal-oral or enteric transmission. It is now recognized as a serious threat to global public health, and has become a major concern in both industrialized and underdeveloped countries. According to the World Health Organization, an estimated 2.3 billion people (a third of the world's population) have already been infected with HEV. In endemic regions such as Asia, Africa and Central America, HEV is the cause of major epidemics of acute hepatitis, mainly of waterborne origin linked to faecal peril. In various industrialized countries of Europe and America, hepatitis E has long been considered an infection contracted during a stay in an endemic zone. Improved virological tools have shown that many cases of hepatitis are in fact a sporadic, locally-acquired form, defining the emerging nature of this infection.
DimethylTryptamine Transdermal Patches
Adherence to prescribed psychiatric and nonpsychiatric medicine is a severe problem among people with mental illnesses, it led to negative health effects. Anxiety is how your brain responds to stress and warns you of impending danger. The most common treatments for anxiety are to avoid alcohol, reduce caffeine intake, physical exercise, quitting smoking, stress management etc. Anti-anxiety drugs mostly are alprazolam, clonazepam, chlordiazepoxide, diazepam and lorazepam. Ayahuasca is a plant-based psychedelic. Psychedelics affect all the senses, altering a person's thinking, sense of time and emotions. The active chemical in ayahuasca is DMT (dimethyltryptamine). DMT targets the serotonin receptors in the brain, working similarly to anti-anxiety.
