The Inflammasome
This volume provides inflammasome instructions and tips to study different aspects of inflammasome biology. Chapters guide readers through how to assess canonical and non-canonical inflammasome activation, in vitro immune and non-immune cells, whole blood, biochemical assays to evaluate ASC oligomerization, gasdermin D cleavage, and mapping phosphorylated residues of NLRP3. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Inflammasome: Methods and Protocols aims to provide protocols that will serve as tools for current and aspiring researchers interested in studying inflammasomes.
On Hippocrates' On the Nature of Man
On the Nature of Man is a work in the Hippocratic Corpus. On the Nature of Man is attributed to Polybus, the son in law and disciple of Hippocrates, through a testimony from Aristotle's History of Animals. However, as with the many other works of the Hippocratic Corpus, the authorship is regarded as dubious in origin.
Non-Alcoholic Steatohepatitis
This volume contains a comprehensive collection of laboratory protocols used by researchers to analyze varied aspects of non-alcoholic steatohepatitis (NASH). The chapters in this book cover topics such as methods for histological diagnosis of NASH; the purpose of generating an in vivo NASH model; protocols for isolating hepatocytes and Kupffer cells, bone marrow derived macrophages, and adipocytes; techniques to develop human pluripotent stem cells-derived liver organoids; single-cell and RNA-sequencing; and a description of how to extract exosomes and exosomal miRNAs from mesenchymal stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Non-Alcoholic Steatohepatitis: Methodsand Protocols is a valuable resource for new and experiences investigators studying NASH, and serves as an essential reference on NASH for basic and clinical researchers and students.
Use of Occlusal splints in Temporomandibular Joint Disorders
Despite the unanswered questions on the physiologic mechanisms that explain the effectiveness of intra-oral appliances on reducing symptoms of TMD, there is still a plethora of documentation that intra-oral appliance when used in the management plan accurately, can contribute to the relief of TMD symptoms. The clinician is encouraged to evaluate fully each particular patient case in an effort to develop a differential diagnosis that leads to effective management plan.Before commencing any appliance therapy for a TMD, the clinician should be confident that the patient will benefit from the therapeutic approach. If the symptoms reduced that will provide additional diagnostic information. The clinician also needs to consider that 40% of patients suffering from TMD demonstrate favorable response to therapy from a placebo effect. As with any treatment, a good patient-dentist relationship and concomitant with patent education, can alloy patient feelings and anxieties. It can contribute to a positive and favorable response to intra-oral occlusal splint therapy.
Challenges in Medical Ethics
This is a book about several specific and serious challenges that bioethics has to deal with in our time, particularly in the South African context. From an almost non-existent 'science' at the beginning of the 20th century, not receiving systematic reflection in intellectual circles such as universities, bioethics has grown with unprecedented strides and has established itself across the world as a major field of study. This book is an acknowledgement of the relevance and actuality of this development of bioethics internationally, and particularly in South Africa. In addition, it is an inter- and multidisciplinary composition of contributors and a significant reflection of the interdisciplinary approach that is universally required for bioethical work. The contributions also testify to a notable diversity in recently researched issues and in the backgrounds of the contributors.
Brain metastases of breast cancer
Breast cancer is the first cancer of women in the world and in Tunisia with an incidence of 46.3 and 37.8 cases / 100 000 inhabitants per year respectively. It is the second cause of cancer mortality in women in Tunisia with 17 deaths / 100 000 inhabitants per year.The management of metastatic breast cancer has undergone several advances over the past decades leading to an improvement in patient survival. However, 15 to 30% of patients will develop brain metastases (BM) during their disease. They can occur synchronously (at the time of diagnosis of the primary cancer) or metachronously (after 6 months of the end of the primary cancer treatment). The management of CD is multidisciplinary, involving neurologists, neurosurgeons, radiologists, radiation oncologists, medical oncologists and pathologists.Radiation therapy (RT) is one of the pillars of CD treatment and has long been the standard treatment with its different modalities.The place of surgery is discussed according to the operability and resectability of metastases, as well as the status of systemic disease.Systemic treatment can be based on chemotherapy, hormonal therapy and targeted therapy and depends on the terrain, molecular classification and previously prescribed treatments.
Oral Bioavailability Enhancement of an Anti-Viral Drug Using an Herbal Bio-Enhancer
The focus on HIV therapy has changed during the last ten years. Long-term treatment of HIV infection is now the norm in industrialised nations because to an expanding selection of effective, practical novel medicines and co-formulations. Because of this, maintaining the efficacy of the treatment has become dependent on tolerance and side-effect control.The majority of those who are infected do not have access to HIV and AIDS medications and therapies because anti-retroviral drugs are pricey. Antiviral medications are linked to a wide variety of adverse responses, metabolic issues, and toxicity, and research is ongoing to reduce the negative effects of currently available medications.Although these medications frequently lack the appropriate pharmacokinetics characteristics, they have great pharmacodynamics characteristics. As a result, it becomes vital to boost pharmacokinetics using the existing methods, such as enhancing lipophilicity and GIT permeability, developing innovative drug delivery systems, and including bio-enhancer in the formulation or dietary supplement. This strengthens the legal basis for choosing a bio-enhancer in the quest to change pharmacokinetic characteristics and reduce toxicity. Those with HIV infection can now live considerably longer with recovered immunity and economy thanks to the alteration in the formulation (using a bio-enhancer) of medications causing notable adverse reactions.
Manual of Embryo Selection in Human Assisted Reproduction
Selecting the best embryo to transfer to the uterus is key to successful in vitro fertilization (IVF). A huge amount of research has been devoted to this topic and there are numerous methods used, from simple morphological assessment to molecular biological techniques to assess the genome and metabolism of the newly fertilized embryo. For many of these techniques, an adequate evidence base is lacking, and expert opinion is valuable. Clinical imperatives require ranking all embryos in a cohort according to their viability, thereby enabling the selection of the best embryo to optimize live birth outcome: a key indicator used to measure and rate IVF Clinics worldwide. This clear and informative manual will provide embryologists and clinicians with an overview of the tools now available to assist in embryo selection, as well as evidence for their efficacy and safety and the broader considerations that must underlie these important clinical decisions.
Introduction to Clinical Reasoning in Physical Therapy
Clinical reasoning (CR) refers to the thinking and decision-making processes that are used in clinical practice. Physical therapy is an important branch of modern medicine which deals with various physical and functional dysfunctions among people in scientific and evidence based ways. The book intends to introduce clinical reasoning and its core concepts to under graduate physical therapy students.
A practical implementation guiding book for emergency Medicine.
This guiding book is aimed to improve quality of care and patient flow on time at emergency medicine and critical care department, HFCSH.It contains a detailed network of Emergency services and resources coordinated to provide aid and medical assistance from primary response to definitive care. A well-organized hospital based emergency medical services from the patient arrival to optimum treatment.
Medieval Medicine
Medieval Medicine, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Epidemiology of Digestive Cancers in Algeria
Digestive cancers, constitute a major and global public health problem, due to their frequency and severity. This is a multicenter descriptive epidemiological study from 2014 to 2018 on all cases of digestive cancers diagnosed in the East and South-East Algerian region. The gender distribution of digestive cancers shows that: In men, colorectal cancer occupies the first place with a crude and standardized rate of 14.6 and 19.3 per 100,000 inhabitants followed by stomach cancer with an average crude and standardized rate of 5.9 and 8.2 per 100,000 respectively, then comes the pancreatic cancer which represents 9.8% of all digestive cancers In women, the same distribution, however it is the cancer of the gallbladder and extrahepatic bile ducts that occupies the third place with a crude and standardized rate of 3.2 and 4.6 per 100 000 inhabitants. Cancers of the esophagus and small intestine are rare, representing less than 3% of digestive cancers. Their frequency will continue to increase in this region if no preventive measures are taken.
Prevention of infection in peritoneal dialysis
Peritoneal dialysis is one of the methods of extrarenal purification in patients with end-stage renal disease and receiving replacement therapy.In 2015, estimates suggest that 272,000 people are on peritoneal dialysis worldwide about 11% of the dialysis population. Infectious complications are the most feared complications of this technique. There are two main types of infections: infections of the catheter outlet and infections of the dialysis fluid. These peritonitises occur essentially as a result of contamination during handling, or either by continuity following an outlet infection or in relation to a bacterial translocation through the digestive wall.The objective of this work is to evaluate the theoretical knowledge and practical conduct of young Tunisian nephrologists in terms of prevention of infectious complications in order to detect the difficulties encountered and remedy them.
Medical Inquiries and Observations (Volume 3); The Second Edition, Revised and Enlarged by the Author
Medical Inquiries and Observations (Volume 3); The Second Edition, Revised and Enlarged by the Author, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medicina Gymnastica; or, A treatise concerning the power of exercise, with respect to the animal oeconomy; and the great necessity of it in the cure of several distempers
Medicina Gymnastica; or, A treatise concerning the power of exercise, with respect to the animal oeconomy; and the great necessity of it in the cure of several distempers, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medical Inquiries and Observations (Volume 2); The Second Edition, Revised and Enlarged by the Author
Medical Inquiries and Observations (Volume 2); The Second Edition, Revised and Enlarged by the Author, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Spinal Cord Injury Rehabilitation in Paraplegics
This is a book which will guide the students and clinical practitioners to explore various concepts related to spinal cord injury rehabilltation.It will guide how to rehabilitate the patient in various stages of recovery of paraplegia.I would highly recommend students to go through its content to cover this broad topic in an easy manner. It also includes description of various orthotic devices.I have tried to cover all the key aspects.
Medical Inquiries and Observations (Volume 4); The Second Edition, Revised and Enlarged by the Author
Medical Inquiries and Observations (Volume 4); The Second Edition, Revised and Enlarged by the Author, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medicine in the Middle Ages; Extracts from Le Moyen Age Medical by Dr. Edmond Dupouy; translated by T. C. Minor
Medicine in the Middle Ages; Extracts from "Le Moyen Age Medical" by Dr. Edmond Dupouy; translated by T. C. Minor, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
How to Stop Coughing
Coughing affects millions of people globally and can be a minor inconvenience or a persistent issue that significantly impacts daily life. People are constantly searching for effective methods to alleviate coughing and find relief from this discomforting symptom.This book is a comprehensive guide that offers valuable insights for individuals seeking to enhance their understanding and management of coughing. Whether short-term or long-term, this book serves as an indispensable resource for improving one's health and quality of life. It delves into the utilization of holistic practices and natural medicine as safe and effective means of alleviating persistent coughing and preventing it from becoming a chronic problem. It is a valuable resource for both the general public and healthcare professionals, providing over 100 proven ways to stop coughing.Designed for those in search of practical solutions to their coughing, the guide presents straightforward and easy-to-follow advice. With its detailed information on holistic practices and natural medicine, this book is a valuable tool for those seeking relief from coughing and a return to a normal, healthy life.
Medical Sketches of the Expedition to Egypt, from India
Medical Sketches of the Expedition to Egypt, from India, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Expanding Mindscapes
The first collection of its kind to explore the diverse and global history of psychedelics as they appealed to several generations of researchers and thinkers. Expanding Mindscapes offers a fascinatingly fluid and diverse history of psychedelics that stretches around the globe. While much of the literature to date has focused on the history of these drugs in the United States and Canada, editors Erika Dyck and Chris Elcock deliberately move away from these places in this collection to reveal a longer and more global history of psychedelics, which chronicles their discovery, use, and cultural impact in the twentieth century. The authors in this collection explore everything from LSD psychotherapy in communist Czechoslovakia to the first applications of LSD-25 in South America to the intersection of modernism and ayahuasca in China. Along the way, they also consider how psychedelic experiments generated their own cultural expressions, where the specter of the United States may have loomed large and where colonial empires exerted influence on the local reception of psychedelics in botanical and pharmaceutical pursuits. Breaking new ground by adopting perspectives that are currently lacking in the historiography of psychedelics, this collection adds to the burgeoning field by offering important discussions on underexplored topics such as gender, agriculture, parapsychology, anarchism, and technological innovations.
Medical symbolism in connection with historical studies in the arts of healing and hygiene
Medical symbolism in connection with historical studies in the arts of healing and hygiene, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
A Mechanical Account of Poisons in Several Essays
A Mechanical Account of Poisons in Several Essays, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medical Inquiries and Observations, Vol. 1; The Second Edition, Revised and Enlarged by the Author
Medical Inquiries and Observations, Vol. 1; The Second Edition, Revised and Enlarged by the Author, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medical experts
Medical experts: Investigation of Insanity by Juries, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medicine in Virginia, 1607-1699
Medicine in Virginia, 1607-1699, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
North Carolina Medical Journal. Vol. 3. No. 4. April, 1879
North Carolina Medical Journal. Vol. 3. No. 4. April, 1879, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Medica Sacra; Or, A Commentary on the Most Remarkable Diseases Mentioned in the Holy Scriptures
Medica Sacra; Or, A Commentary on the Most Remarkable Diseases Mentioned in the Holy Scriptures, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Notes on Maritime Medicine
Maritime medicine represents an area of medicine that has origins dating back to Egyptian, Greek, Roman, Viking and European times. Seafarers have been the pioneers in the exploration of new continents, they have accessed territories that have given mankind access to resources found in other regions. The practice of maritime medicine requires that the professional has a series of skills and competencies that include a deep knowledge of the subject, professional ethics, ability to work in teams and interact with professionals from different areas, an openness to multicultural treatment, relations with international organizations to meet requirements for the transport of people and goods at the international level. This work is a compendium of some of the training activities that should be developed by students of the maritime medicine specialty program at the UCA and can serve as a first contact with the subject and reference for people who start learning in this specialized medical area and unknown to most of the medical staff at international level, we hope it will be useful.
Medical Women
Medical Women: Two Essays, has been acknowledged as a major work throughout human history, and we have taken precautions to assure its preservation by republishing this book in a modern manner for both present and future generations. This book has been completely retyped, revised, and reformatted. The text is readable and clear because these books are not created from scanned copies.
Enzymology of Complex Alpha-Glucans
Glycogen and Starch: So Similar, yet so Different. Both carbohydrates are central to the primary metabolism of a large part of the living kingdom. Generally, animals, fungi, and bacteria store glycogen, while plants largely rely on starch. This book provides a broad and current view on both glycogen and starch, in lower and higher organisms. Beside biochemistry, physiology and regulation of glycogen and starch metabolism, the reader can expect an insight into glycogen storage diseases, select methods and relevant techniques. While significant progress has been made in both fields, this volume emphasizes an opportunity of collaboration for researchers working on a major intersection of the living world.
Giant-Cell Arteritis
Giant cell arteritis (GCA) is a systemic vasculitis that affects medium- to large-size arteries in which an inflammatory reaction destroys the media of the artery wall with the fragmentation of the elastic lamina, which can result in acute vision loss if not treated in a timely manner. The other common visual symptoms may include diplopia due to cranial nerve palsies and transient visual loss. This book provides a comprehensive overview of GCA, with chapters on epidemiology, cellular and molecular characteristics of the disease, extra-cranial involvement of GCA, medical imaging, and much more.
HIV and Tuberculosis
Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities.The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike.
Dialysis Essential & Its System Elements
Dialysis technicians, nurses, and purchasing managers will benefit from these new patented dialysis tools that can be used to help enhance patients' health-tools that are more important than ever during today's pandemic. These tools were designed to help improve patients' URR and clearance and help them feel much better. Dialysis Essential & Its System Elements is a must-read for those who care for dialysis patients.
The Stories We Can Tell
A behind-the-scenes look at the on-board experiences in the lives of cruise ship nurses.
Biochemistry and Therapeutic Attributes of Culinary Herbs
India has been recognized as the Land of Spices from the dawn of time due to the cultivation of such a broad range of spice crops and represents the status of the world's one of the leading spice producers and exporters, accounting for around 25-30% of the global spice commercially. The scent, flavor and pungency of Indian spices are well-known. The present book deals with the characteristics of some important Indian spices, their usages, active components present in them along with exploring their health benefits, functional and immunomodulant properties. The toxicological aspect and adverse effects of the spices are not covered in this book
Fungal infestation of onion bulbs during storage in sack and on its antioxidant properties
Electrophysiology
This updated and revised textbook presents a broad overview on topics concerning cellular electrophysiology - ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and modern applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text. Each chapter is extended by a detailed table of Take-Home Messages. Questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.
Evaluation Methods in Biomedical and Health Informatics
A broad update of the very successful first edition, Evaluation Methods in Medical Informatics is a comprehensive how-to guide full of evaluation techniques for a range of informatics professionals. This guide to successful health information system evaluation is an invaluable resource for all levels of informatics professionals, from student to on-site system administrator.
All About Clinical Research
The purpose of this book is to provide novice and experienced clinical research professionals with a fun and effective way of learning and remembering the information found in ICH guidelines for Good Clinical Practice through word searches and flash cards. - Use the word search activities to help with word associations to help focus on and learn the different parts of the ICH Guidelines for Good Clinical Practice. The consolidated tripartite harmonized ICH- Good Clinical Practice [E6 (R2) - the Integrated Addendum to E6(R1)], General Considerations for Clinical Trials [E8 (R1)], and Clinical Safety Data Management (E2A), as published in the U.S. Federal Register May 9, 1997 and March 1, 1995 respectively, are attached to this book for your easy reference when solving the word search puzzles. - Use the flash cards as a tool for remembering specific GCP rules and CFR regulations in clinical research.
Genetics
Genetics is a branch of biology that deals with the study of genes, genetic changes and inheritance in living organisms. Mendel studied the inheritance of traits, which is a model of how traits are passed from parents to children. He observed that organisms inherit discrete units of traits. This term, which is still used today, is a somewhat vague definition of what is referred to as a gene. Inheritance of traits and molecular genetic mechanisms of genes are still the main principles of genetics in the 21st century, but modern genetics has gone beyond inheritance to study the function and behavior of genes. Gene structure and function, diversity and distribution are studied in the text of the cell, organism and in the context of the population. Genetics has created various fields such as molecular genetics, epigenetics and population genetics.
Contraception and Modern Ireland
Contraception was the subject of intense controversy in twentieth-century Ireland. Banned in 1935 and stigmatised by the Catholic Church, it was the focus of some of the most polarised debates before and after its legalisation in 1979. This is the first comprehensive, dedicated history of contraception in Ireland from the establishment of the Irish Free State in 1922 to the 1990s. Drawing on the experiences of Irish citizens through a wide range of archival sources and oral history, Laura Kelly provides insights into the lived experiences of those negotiating family planning, alongside the memories of activists who campaigned for and against legalisation. She highlights the influence of the Catholic Church's teachings and legal structures on Irish life showing how, for many, sex and contraception were obscured by shame. Yet, in spite of these constraints, many Irish women and men showed resistance in accessing contraceptive methods. This title is also available as Open Access.
Contraception and Modern Ireland
Contraception was the subject of intense controversy in twentieth-century Ireland. Banned in 1935 and stigmatised by the Catholic Church, it was the focus of some of the most polarised debates before and after its legalisation in 1979. This is the first comprehensive, dedicated history of contraception in Ireland from the establishment of the Irish Free State in 1922 to the 1990s. Drawing on the experiences of Irish citizens through a wide range of archival sources and oral history, Laura Kelly provides insights into the lived experiences of those negotiating family planning, alongside the memories of activists who campaigned for and against legalisation. She highlights the influence of the Catholic Church's teachings and legal structures on Irish life showing how, for many, sex and contraception were obscured by shame. Yet, in spite of these constraints, many Irish women and men showed resistance in accessing contraceptive methods. This title is also available as Open Access.
Netley Diary 1915-1916
"I was after all the experiences I could collect, and wanted to know what a great military hospital was like ... I had to go to one, and decided on the grand style of doing it."Corporal Alec Riley was a signaller in the British Army's 42nd (East Lancashire) Division who served at Gallipoli in 1915. Four months on the peninsula left him debilitated, suffering nine septic sores and no less than four diseases - diphtheria, jaundice, enteritis and dysentery. Riley was evacuated by sea to the Greek island of Lemnos, 50 miles from Cape Helles on the peninsula. Here he survived five weeks in the care of an Australian field hospital before being stretchered onto a hospital ship bound for England. It was during the passage home that Riley decided on 'the grand style of doing it' and chose the Royal Victoria Hospital, Netley, as his destination.When it opened in 1863, Netley was the largest military hospital in the world, with more than 1,000 beds. During the First World War, capacity was doubled, and beds filled the corridors. Two temporary hutted hospitals were erected in the grounds behind the main building as the tide of sick and wounded from Gallipoli, the Western Front and other theatres of war rose."I have tried," says Riley, "to give some idea of life in one of the many wards, the various patients I met, our habits, amusements, hopes and fears."The diary chronicles Riley's last days on Gallipoli, his experiences of No. 1 Australian Stationary Hospital at Mudros, his passage home on the hospital ship Aquitania and his 11 months at Netley and its auxiliary hospitals, Shirley and Shorne Hill.With dry humour, Riley relates the small mischiefs between the convalescents and the medical staff. He tells of concert parties in the hospital's theatre, and recalls the songs of the time. He reflects on the efforts of the chaplains, whose efforts to elevate the 'army in blue' often missed the mark. One spoke on the evils of the rum ration, until a voice shouted "Have you ever been over the top?" Another chose to speak on the good that war does. "An unsavoury subject in a military hospital," thought Riley, "but we were curious to hear what good he thought it did."Most of all, Riley relates the experiences of a soldier, sick and broken, taking the journey shared by so many away from the front and on the slow road to recovery, a journey in his case that took more than a year. The book is richly illustrated with rarely seen images and three specially-produced maps.Included is a concise history of the Royal Victoria Hospital, as well as biographies of the author, his sister and two close comrades at Gallipoli.
Chasing Tourette's: Time, Freedom, and the Missing Self
This book offers a philosophical perspective on contemporary Tourette Syndrome scholarship, a field which has exploded over the last thirty years. Despite intense research efforts on this common neurodevelopmental condition in the age of the brain sciences, the syndrome's causes and potential cures remain intriguingly elusive. How does this lack of progress relate to the tacitly operating philosophical concepts that shape our current thinking about Tourette Syndrome? This book foregrounds these tacit concepts and shows how they relate to "big topics" in philosophy such as time, volition, and the self. By tracing how these topics relate to current research on Tourette's, it invites us to re-think our approach to research and care. Such re-thinking is urgently needed: individuals and families living with Tourette Syndrome remain under-serviced as pharmacological and behavioural therapies provide relief for some but not all who need support. This book highlights what questions we ask and do not ask in contemporary scholarship, thereby surfacing invisible constraints and opportunities in the field. It is of interest to scholars, health professionals, students, and affected families who want to better understand this burgeoning field of research with its conceptual controversies, approaches to aetiology, and directions for new research and improved clinical care.
Infectious lung disease
Acute community-acquired pneumonia (CAP) in adults is a public health problem with a significant morbidity and mortality. Chest radiography is the only radiological diagnostic test that is recommended as a first step. Computed tomography (CT) is usually indicated in case of clinico-radiographic discordance. The aim of our study was to evaluate the diagnostic contribution of this examination in patients hospitalized for CAP and its impact on their therapeutic management.
