Hyperthermic and Hypermetabolic Disorders
This authoritative and comprehensive new publication looks in depth at a range of medical syndromes characterized by serious and unpredicted internal overheating of the body. As a result of heat stress, exceptional physical exertion, or in response to certain drugs, these episodes may arise suddenly and unexpectedly, with life-threatening consequences. This text's contributions focus on the full range of these syndromes, their metabolic and physiological bases, the important predisposing factors that determine those at risk, and the medical management of these conditions. The volume incorporates a wealth of information from the Leeds Malignant Hyperthermia Investigation Unit--the world's leading center of research and investigation in this area.
Travels With Shubh
For over a decade, MetaWorks was a pioneer in both the science and business of Evidence-based Medicine. Travels with Shubh is a co-founder's memoir of the MetaWorks journey, as told through a series of vignettes anchored in the personal mantras of one unusual change agent who was integral to its success. The MetaWorks story vividly illustrates the highs and lows of a healthcare start-up, while at the same time providing a unique glimpse into the ongoing evolution of healthcare analytics and the business of medicine.
Lethal Witness
Sir Bernard Spilsbury was an early-twentieth-century British forensic pathologist who gained fame by testifying in classic murder cases, beginning in 1910 with the Dr. Hawley Harvey Crippen trial. His expert court testimony--he identified Crippen's victim by detailed microscopic study of a scar--convinced the lay jury of Crippen's guilt. Considered the father of modern forensic pathology, Spilsbury became well known after he provided crucial prosecutorial evidence in the Brides in the Bath case (where a nurse nearly drowned in a laboratory experiment designed to prove his theories), the Blazing Car and Brighton Trunk murders, and the Hay-on-Wye arsenic poisoning trial. Knighted in 1923, Spilsbury performed 20,000 postmortem examinations and became the first and only "Honorary Pathologist to the Home Office." Controversial and dramatic, Lethal Witness charts Spilsbury's rise and fall as a media star, revealing how he put spin on the facts, embellished evidence, and played games with the truth. In some notorious cases, his "positive evidence" led to the conviction and execution of men innocent of murder--gross miscarriages of justice that now demand official pardons. Andrew Rose examines Spilsbury's carefully nurtured image, dogmatic manner, and unbending belief in his own infallibility and exposes the fallacies of the man dubbed "the most brilliant scientific detective of all time." True crime fans, students of forensics, and law enforcement professionals will enjoy this biography of Sir Bernard Spilsbury, the man who helped raise forensic science to an art.
Interventional Radiological Treatment of Liver Tumors
Interventional radiological techniques are becoming increasingly important in the treatment of both primary and secondary malignant liver tumours. Surgery for liver tumours can be effective but carries considerable risks and new techniques have recently been developed. This volume provides an account of interventional radiological methods by some of the greatest experts in the field. It includes chapters on cryotherapy, chemoembolization and radiofrequency ablation and an extensive chapter on imaging techniques. The scientific background of these techniques, the pathology of the diseases involved and an analysis of more traditional surgical methods are also described. This text brings together the latest advances in this fast-developing field.
