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Evidence-Based Clinical Chinese Medicine - Volume 22
Urinary tract infection is a common clinical condition with a significant health burden. This latest volume, Vol. 22 in the Evidence-based Clinical Chinese Medicine series, uses a 'whole evidence' approach to summarise management of urinary tract infection with Chinese medicine. The first chapter provides an overview of the clinical presentation, diagnosis and treatment with conventional medicine. The conceptualisation of urinary tract infection in both contemporary and classical Chinese medicine literature is reviewed and analysed.Attention is then turned to the evidence from clinical studies. Systematic reviews, using internationally accepted scientific methods, describe the treatments tested in clinical studies and the effects of Chinese herbal medicine, acupuncture and related therapies, and combinations of these therapies for urinary tract infection. The potential mechanisms of action for some of the key herbs are summarised, based on analysis of experimental studies. The final chapter summarises the current state of evidence and offers suggestions for contemporary clinical practice and future research.This book is a handy desktop reference for both clinicians and students of Chinese and integrative medicine. It provides a comprehensive synthesis of both traditional and contemporary knowledge that can inform clinical decision-making.This book provides an in-depth analysis of Chinese medicine management of urinary tract infection.
Handbook of Intensive Care
The diagnosis and management of various life-threatening conditions require sophisticated care and life support, as well as intensive monitoring. Such care is under the scope of intensive care medicine. Lethal cardiac arrhythmias, acute renal failure, multiple organ failure, cardiovascular instability and airway or respiratory compromise are some of the conditions that require intensive care. Serious infections such as severe pneumonia or sepsis, lethal short-term conditions like a heart attack or stroke, and major accidents also qualify for intensive care. Various equipment may be used in an intensive care unit or facility, such as a ventilator, monitoring equipment for assessing blood pressure, heart rate and oxygen levels in blood, feeding tubes, etc. This book aims to shed light on some of the unexplored aspects of intensive care and the recent researches in this field. Most of the topics introduced herein cover new techniques and the applications of intensive care medicine and support. For all those who are interested in this field, this book can prove to be an essential guide.
Pharmaceuticals: Drug Development, Design and Manufacturing
A pharmaceutical drug is a compound which is used for the diagnosis, treatment and prevention of a disease. It can be classified depending on the level of control, mode of action, route of administration and therapeutic effects, among others. Some classes of medicine are antibiotics, antipyretics, analgesics, antiseptics, oral contraceptives, tranquilizers, stimulants, etc. The development of pharmaceutical products traverses a number of stages from drug discovery to commercialization. There exists a clear distinction between small molecule drugs and biologic medical products. While small molecule drugs are developed through chemical synthesis; biologic medical products include vaccines, recombinant proteins, gene therapy and cell therapy. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of pharmaceuticals. It presents researches and studies performed by experts across the globe on potential pharmaceutical agents. With state-of-the-art inputs by acclaimed experts of this field, this book targets students and professionals.
Recent Progress in Particle Toxicology
The inhalation of harmful airborne particles may result in adverse health conditions and pathological changes in the respiratory tract. It is often seen that noxious inhaled particles activate an inflammatory pulmonary response, which can initiate a sub-chronic or chronic pulmonary disease. These conditions may include silicosis, pneumonitis, chronic obstructive pulmonary disease, asbestosis, emphysema, fibrosis, asthma or cancer. The severity of a particle-induced pathology is dependent on the exposure time and concentration as well as particle size, structure and composition. Airborne particles may include combustion-derived particles from welding, cigarette smoke, traffic and industry, etc. as well as biological particles such as pollen and fungi. Research on particle toxicology attempts to investigate the effects of individual particles and sources. This enables better predictability of newly generated particles. In vivo toxicological studies screen for long-term effects in the respiratory tract. Such studies include the histopathological analysis of the lungs for investigating adverse effects of particles. This book provides comprehensive insights into the field of particle toxicology. The topics included herein are of utmost significance and bound to provide incredible insights to readers. It will prove to be immensely beneficial to students and researchers in toxicology.
Pharmaceutical Practice and Policy
Pharmaceutical policy is a field which deals with the development, use and provision of medications within a healthcare system. It encompasses biologics, drugs, vaccines and natural health products. Patent laws apply to all pharmaceutical products. Thus, the interpretations of these made by government patent granting agencies can have significant impacts on the incentive to drug development. These also have consequences on the availability of lower-priced generic drugs. Another important dimension of pharmaceutical practice is licensing. A recognized national agency is mostly responsible for reviewing a product and approving its sale. Quality, safety and efficacy are the chief determinants of drug regulation. Once the safety and clinical benefits of a product have been established and its pricing has been determined, a drug manufacturer submits it for evaluation by a payer. This book provides comprehensive insights into pharmaceutical policy and practice. It outlines the varied aspects of pharmaceutical regulation, legal issues and administrative dimensions of pharmaceutical practice in detail. As this field is constantly evolving, the contents of this book will help the readers understand the modern concepts and developments in this domain.
Traditional Chinese Medicine
The branch of traditional medicine which is based on ancient Chinese medical practices is known as Traditional Chinese Medicine or TCM. There are various forms of medicine which are considered to be a part of TCM such as cupping therapy, bonesetter, gua sha, acupuncture and herbal medicine. The primary belief of TCM is that the body's vital energy, which is also called chi, circulates through channels, which are called meridians. The functions of the body such as breathing and digestion are the primary focus of this branch of medicine, instead of the anatomical structures. This book provides significant information of this discipline to help develop a good understanding of Traditional Chinese medicine and related fields. Some of the diverse topics covered in it address the varied branches that fall under this category. This book is appropriate for students seeking detailed information in this area as well as for experts.
Particle and Fibre Toxicology
Airborne particles when inhaled, can lead to pathological changes in the respiratory tract. Therefore, toxicological studies on the effects of inhalable fibers and particles involve an assessment of the histopathological alterations in the trachea, lungs and the upper respiratory tract. The pathology of particle and fibre toxicology depends on the exposure source, duration, concentration and individual predisposition. Particles such as combustion-derived particles, engineered nanoparticles, ultrafine particles, silica, asbestos, etc. can induce an inflammatory response. There may be long term effects of chronic particle exposure, such as allergic airway inflammation, chronic obstructive pulmonary disease, fibrosis or neoplasms. The extent of tissue damage and pulmonary inflammation can be addressed and studied via pulmonary histopathology as well as diverse histopathological inflammatory parameters. This book unfolds the innovative aspects of particle and fibre toxicology which will be crucial for the progress of this field in the future. It will also provide interesting topics for research which interested readers can take up. It attempts to assist those with a goal of delving into toxicology.
Handbook of Particle Toxicology
Particle toxicology is the field concerned with the toxicity of particles and fibers. The characteristics of different particles are investigated to determine their levels of toxicity and the pathobiological mechanism of that lethality. This enables the assessment of risks relative to exposures and the development of interventions to prevent progression. Historically, coal, quartz, asbestos, glass fibres and environmental particles have had a negative impact on human health. In the era of nanotechnology, nanotoxicology has emerged as a new domain in particle toxicology. Of all possible hazards, inhalation exposure presents the most concern with researches showing pulmonary conditions such as fibrosis, inflammation and carcinogenicity being the most likely outcomes of exposure to nanomaterials. Ingestion exposure and skin contact are the other major concerns. This book elucidates new techniques and applications of particle toxicology in a multidisciplinary manner. It explores all the important aspects of particle toxicology in the present day scenario. It will prove to be immensely beneficial to students and researchers in this field.
Advances in Kinesiology and Sports Science
The scientific study of human and non-human movement is known as kinesiology. It encompasses the physiological, psychological and biochemical dynamic principles and mechanisms of movement. The branch of kinesiology which deals with the human health is known as human kinesiology. It studies biomechanics and orthopedics, sports psychology, and strength and conditioning. Human kinesiology also includes methods of rehabilitation such as physical and occupational therapy, and sports and exercise. Sports science is a field that observes the functioning of a healthy body during exercise. It studies how physical activities such as sports promote the health and performance of the whole body. It encompasses various areas such as biokinetics, biomechanics and anatomy. This book discusses the fundamentals as well as modern approaches to kinesiology and sports science. It presents researches and studies performed by experts across the globe. Those in search of information to further their knowledge will be greatly assisted by this book.
Pharmacogenomics and Personalized Medicine
Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient's genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is still poor. Many coordinated international efforts are ongoing in order to overcome the existing barriers to pharmacogenomic implementation. On the other hand, existing validated pharmacogenomic markers can explain only a minor part of the observed clinical variability in the therapeutic outcome. New investigational approaches are warranted, including a study of the pharmacogenomic role of the immune system genetics and of previously neglected rare genetic variants, reported to account for a large part of inter-individual variability in drug metabolism. In this book, we have collected a series of articles covering many aspects of pharmacogenomics. These include clinical implementation of pharmacogenomics in clinical practice, development of tools or infrastructures to support this process, research of new pharmacogenomics markers to increase drug efficacy and safety, and the impact of rare genetic variants in pharmacogenomics.
Monitoring for Health Hazards at Work
MONITORING FOR HEALTH HAZARDS AT WORK Monitoring for Health Hazards at Work remains the seminal textbook on measuring and -controlling the risk of workplace exposure to physical, chemical, and biological hazards. Designed for students studying occupational hygiene and exposure science, this comprehensive and accessible volume provides step-by-step guidance on identifying hazards and quantifying their risks in various workplace environments. Complete with checklists and practical examples, the authors present clear explanations of all types of hazards that can arise in the workplace, including dust, particles, fibrous aerosols, gases, vapours, and bioaerosols.The fifth edition features revised material throughout, and remains an essential resource for students and professionals in occupational hygiene, reflecting global standards and recent developments in monitoring equipment, modelling methods, exposure assessment, and legislation on workplace safety. Several new or substantially revised chapters cover topics such as human biomonitoring, exposure modelling, hazardous substances, physical agents, evaluating ventilation, PPE, and other control measuresUpdated sections discuss the equipment currently available, the importance of risk communication, assessing dermal and inadvertent ingestion exposures, and moreExamines common workplace comfort issues such as noise, vibration, heat and cold, and lightingOffers practical advice on conducting and presenting risk assessments and reportsDiscusses the future of the development and application of hazard measurement equipment and methodsMonitoring for Health Hazards at Work, is required reading for students and professionals in occupational hygiene, environmental health and safety, occupational health and safety, and exposure science.
Science of Spices and Culinary Herbs Volume 2
Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbsand spices have been used for treating various ailments since ancient times.Modern scientific methods have enabled researchers to isolate bioactivecompounds from herbs and spices and perform chemical analyses, which can beused to develop medicines to treat different diseases. This book series is acompilation of current reviews on studies performed on herbs and spices. Scienceof Spices and Culinary Herbs is essential reading for medicinalchemists, herbalists and biomedical researchers interested in the science ofnatural herbs and spices that are common part of regional diets and folkmedicine. The second volume of this series features 6 reviews of unique herbs andseeds:1. Tamarind (Tamarindus indica L.): A Review of itsUse as a Spice, a Culinary Herb and Medicinal Applications2. Piper nigrum (Black pepper): A Flavor for Health3. Coriander Seeds -Ethno-medicinal, Phytochemical and Pharmacological Profile4. The Fenugreek Seed: Therapeutic Properties and Applications5. Biological Activities ofFoeniculum vulgare Mill6. Exploration of DillSeeds (Anethum graveolens): AnAyurpharmacomic Approach
Pharmaceutical Supply Chains - Medicines Shortages
This book provides an insight of relevant case studies and updated practices in "PharmaceuticalSupply Chains" (PharmSC) while addressing the most relevant topics within the COST Action "Medicines Shortages" (CA15105).The volume focuses on the most recent developments in the design, planning and scheduling ofPharmSC, broadening from the suppliers' selection to the impact on patients and healthcaresystems, addressing uncertainty and risk mitigation, and computational issues. It is directed at MSc/PhD students and young researchers (Post-Docs) in Pharmaceutics/Pharmaceutical sciences, Engineering fields, Economics/Management, as well as pharmaceutical decision makers, managers, and practitioners, and advanced readers demanding a fresh approach to decision making for PharmSC. The contributed chapters are associated with the homonymous COST Training Schools (TS), and the book creates a better understanding of the Action "Medicines Shortages" challenges and opportunities.
Intuitive Medicine
ABOUT THE BOOKWhat invisible biological battle is humanity fighting right now? Knowing the real enemy is the key to finding the cure.Through a combination of medical research, firsthand observation, and ideasthetic visualization, the author arrives at an unexpected insight about what really causes most incurable diseases of modern humanity. She then explores unexpected factors that, according to her findings, prolong one's lifespan and ensure physical beauty well into old age.ABOUT IDEASTHESIAIdeasthesia is a rare neurological phenomenon that augments human thinking, by providing allowing processing abstract information through five of the human senses, where abstract objects behave according to physical laws. This very poorly studied human ability can potentially help science tackle the most inaccessible and difficult questions, including organization of the human brain itself.DISCLAIMER This book is a compilation of ideas for educational purposes only, and is not meant to diagnose or treat any disease. Its sole purpose is to stimulate discussion on medical topics, offering alternative views, which are nothing more than hypotheses. ABOUT THE AUTHORVera Dragilyova is a Synesthete and an Ideasthete. She studied Cognitive Science at UC Berkeley, Information Design at Bentley University. She is a life-long researcher, filmmaker, singer, polyglot, and a world traveler.
Moothra Chikithsaanaa Kudarthee Laabh
Natural Benefits of Urine Therapy is one of the "Educational Sections on Secret of Excellent Health" for everyone to maintain a healthy life. It has natural healing powers to control and cure all kinds of diseases. Urine Therapy or "Shivambu" is an ancient method of treatment. Reference of Urine Therapy is found in almost all the volumes of Ayurveda. In ancient books and Vedas, Urine is referred to as "Shivambu" (auto-urine), which means Water of Shiva. They termed "Shivambu" as holy liquid. According to them, urine is more nutritious than milk. Urine Therapy is an effective system and it is entirely drugless system of healing all chronic disease. It can be adopted by everyone including young children suffering from cerebral palsy from the very birth.
Therapy and Prevention of Atopic Dermatitis and Psoriasis
Atopic dermatitis and psoriasis are common inflammatory skin diseases. The excellent therapeutic success of anti-IL-4/IL-13 biologics for atopic dermatitis and anti-TNF-α/IL-23/IL-17A biologics for psoriasis highlights the major pathogenic roles of these cytokines in the respective diseases. Although atopic dermatitis and psoriasis are distinct clinical entities, they share similar inflammatory processes, including increased Th17, Th22, and Th1 signatures. In addition to skin inflammation, both skin diseases exhibit a significant association with systemic diseases such as cardiovascular diseases, metabolic syndrome, and autoimmune diseases. In contrast to atopic dermatitis, males are more susceptible to psoriasis than females. Differential risk factors may be involved in the development and exacerbation in atopic dermatitis and psoriasis. In this issue, we will publish cutting-edge information regarding skin inflammation, clinical aspects, risk factors, microbiome, and therapeutics related to psoriatic and atopic inflammation.
Cutting Edge Preclinical Models in Translational Medicine
In vitro, in vivo, and in silico preclinical models hold a widely acknowledged potential, yet complex limitations. For this reason, which has been known for a long time by experimenters and modelers, the translation of "science products" to the clinic is still far. Therefore, there is a raising awareness of the need to bridge this gap by developing integrated and innovative models. Organ and tissue bioengineering is an ideal approach to foster innovative strategies in significant research and clinical areas. Similarly, in translational neuroscience research, this challenge has been taken up by intriguing fish models. However, much research based on novel methodologies has still to be performed to get the bench closer to the bedside.
Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm
Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.
Selected Papers from the 3rd International Symposium on Life Science
This book contains information for specialists in various fields of science. From the point of view of pharmacology, data are reported regarding the effect of echinochrome A and related metabolites from sea urchins on the survival and functional properties of stem cells, which can facilitate ex vivo application of this compound in medicine. For scientists who isolate and establish structures of marine natural compounds, an article devoted to the proof of the microbial origin of a typical metabolite earlier found exclusively from marine invertebrates, 6-epi-monanchorin, may also be of interest. A range of new marine metabolites was discovered from the both marine invertebrates and marine microorganisms, particularly in marine isolates of fungi. Some marine natural products could be applied to treat such diseases as Parkinson's disease, ischemic stroke, viral infections, and so on. Magnificamide, a new peptide from sea anemones, inhibits porcine and human saliva amylases, showing its probable antidiabetic properties. Application of the genomic approach was discussed in studies on various marine bacteria, producing marine enzymes with unusual specificity. The lectins capable of recognizing glycoforms of different substrates demonstrate the possibility to be used to elaborate new medical diagnostics.
Effect of Losartan on experimentally induced hyperuricemia in rats
Dr Jagdish Kakadiya is currently working as associate professor in department of pharmacology at Parul Institute of Pharmacy and Research, Parul University. He has not only the experience in the teaching field but has the experience of working as an examination coordinator. He is CPCSEA Nominee in many academic institutes and industries. Apart from this he has the technical experience in conducting experiments like Myocardial and Renal Ischemia/Reperfusion Injury (In Vivo) etc. He has been into handling of instruments like Student Biopac data acquisition system (MP30) and Physiograph etc. He has published more than 22 research and review papers in national & international UGC approval journals. He is including as Editor board Member, Chief Editor or Advisory board member or Reviewer in many national and international journal. He has also presented several papers in national & international conferences. He has 7 h-index and 4 i10 Index in Google Scholar.
Don't Be Sad
Don't Be Sad is an absolute must-read for all people. It is full of practical advice on how to replace sadness with happiness. All proceeds are donated to Huntington's research. The author wrote this book after his little girl died from Huntington's disease. The author shines a light on why happiness is so elusive for many of us and shows you where to find your greatest joy. The author wrote this book for anyone who is searching for happiness or who is living through pain and grief or who has been afflicted with a hardship that results in sadness and restless nights. ts.Don't Be Sad: If God wills good for someone, He afflicts him with trials. Even though we may like living in sin, difficulty is a blessing in our lives because it makes us realize that we have been leading impure lives. As a result, we turn to the correct and holy path
Don’t Be Sad
At a time in which the people are beset with trials from every periphery and within, comes this heartening book rooted in the commandments of Allah (swt), the Sunnah and the excellent guidance and examples of the people that have come before us. Don't Be Sad is an absolute must-read for all people. It is full of practical advice on how to replace sadness with a pragmatic and ultimately satisfying Islamic outlook on life. It exposes to the modern reader how Islam teaches us to deal with the tests and tribulations of this world. So, take heart and hold firmly onto the rope of Allah (swt
New Mechanisms of Action of Natural Antioxidants in Health and Disease
This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.
Polysaccharide Based Nano-Biocarrier in Drug Delivery
This book discusses aspects of polysaccharide based nano-biocarrier drug delivery systems & its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses its ways in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.
Randomized Clinical Trials of Nonpharmacological Treatments
Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable devices, non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. This book focuses on the methods of assessing nonpharmacological treatments, highlighting specific issues, and discussing trial design
Chemical Exposure & Toxic Responses
This book presents the scientific basis of toxicology as it applies to the workplace, covers the diverse chemical hazards encountered in modern work environment, and provides a practical understanding of these hazards for those concerned with protecting the health of people at work.
Benefit-Risk Assessment in Pharmaceutical Research and Development
Bringing together the expertise of 15 contributors from academia and the industry, this book offers an easy-to-read guide to the various facets of benefit-risk assessment in the major stages of pharmaceutical R&D, from early clinical development to late-stage development to regulatory review to post-launch assessment. Suitable for those in b
Thermal Analysis of Pharmaceuticals
This book presents reliable and versatile characterization tools for the development of pharmaceutical products. It highlights the ability of thermal methods to characterize almost any sample, while remaining inexpensive, and operator friendly. The book focuses on widely applicable methods and demonstrates how to interpret associated data. It co
The Role of the Pharmacist in Patient CareTheRole of the Pharmacist in Patient CareAchievi
The goal of a high quality, cost-effective and accessible health care for patients is achieved through constructing a team-based and patient-centered health care delivery system. The expanded role of pharmacists uplifts them to patient care from dispensing and manufacturing or marketing of drugs. Along with doctors and allied health professionals, pharmacists are increasingly recognized as an integral part of the patient care team. Furthermore, colleges of pharmacy need to revise and up-date their curricula to accommodate the progressively increasing development in the pharmaceutical education and the evolving new roles of practicing pharmacists in patient care settings. This book focuses on the expanded role of the pharmacists in total patient care including prescribing, dispensing, compounding, administering and monitoring of drugs at home, hospital, community, hospice, critical care, changeover and other care settings. The sector is emerging in both developed and under-developed countries. Overburdened by patient loads and the explosion of new drugs physicians turn to pharmacists more and more for drug information especially within institutional settings. And today's patient care pharmacists are taking more interests in medication review and reconciliation, patient education and counseling, creating drug therapy regimen and monitoring compliance. The purpose of this book is to guide the pharmacists in their daily interactions with patients and to ensure collaboration with other health professionals. The contents are mostly based on recently published articles related to patient care, with most recent ideas and activities followed by the patient care pharmacists around the globe. However, a pharmacist implements the care plan in collaboration with other health care professionals and the patient or caregiver. Along with professional guidelines, the book discusses the concepts and best practices of patient interaction, patient rights, and ethical decision-making for the professional pharmacist, apprentice and student. In every chapter, the role of pharmacists in that chapter specific issues are detailed explicitly so that a professional pharmacist or a student can figure out his or her do's and don'ts in that specific situation. Moreover, further reading references are listed as future recommendations. So, the book is an archive of potential references too. Among so many books about patient care, either doctors' or nurses' roles are highlighted. The proposed book highlights the pharmacists' roles and responsibilities to the most, separated from those of doctors and nurses, with the most recent information obtained from most publications in several journals, books, bulletins, newsletter, magazines etc.
Nutritional Management and Outcomes in Malnourished Medical Inpatients
Malnutrition lurks in the background of hospitalized medical patients. A large proportion of patients are malnourished upon hospital admission and patients often experience further nutritional deterioration during their stay and during disease recovery. However, although the negative effects of malnutrition on the outcomes of patients are well recognized, we still struggle to identify appropriate patients and efficacious nutritional interventions to overcome this problem. Recent studies have produced convincing evidence that adequate and timely nutritional management of medical in-patients can contribute to the prevention of negative consequences and thus improve the clinical outcome of patients. This Special Issue of the Journal of Clinical Medicine focuses on multiple practical aspects of nutritional management of medical in-patients, from screening for nutritional risk to the practical implementation of nutritional therapy and its possible complications, including financial aspects, to increasing clinician awareness and knowledge of nutritional care in hospitals.
Sleep and Psychosomatic Medicine
Sleep medicine has become the focus of intense medical and scientific interest, growing in tandem with the recognition that sleep disorders represent a major public health concern. This book broadly covers the interface of sleep and consultation-liaison psychiatry. It presents an overview of sleep medicine and the management of common sleep diso
Lightning Injuries
Lightning Injuries: Electrical, Medical, and Legal Aspects presents a thorough examination of injuries inflicted by lightning strikes.
Biological and Pharmaceutical Applications of Nanomaterials
This book covers stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for drug delivery and dental applications. It describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial na
Regional Scale Ecological Risk Assessment
Addressing large-scale and comparative risks at the landscape level, this book focuses on assessments using the Relative Risk Model (RRM) pioneered over the last seven years, and includes case-studies from around the world.
Biotechnology: Recent Trends and Emerging Dimensions
Biotechnology is a multidisciplinary field encompassing microbiology, bichemistry, genetics, molecular biology, chemistry, immunology, cell and tissue culture physiology. Current research topics such as Quorum sensing, Integrons, Phytomining are discussed, which would serve as an excellent reference work for both academicians and researchers.
Biopharmaceutical Sequential Statistical Applications
Focusing on group sequential procedures, summarizes the sequential statistical methods used in anticancer, antiviral, cardiovascular, and gastrointestinal drug research and screening. The clinical and preclinical applications are mainly presented as case studies, many of which form part of New Drug
Radiopharmaceuticals
This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It compares various radiopharmaceuticals and provides guidance on dose estimation and agent selection, covering standard medical internal radiatio
3D Printing of Pharmaceuticals and Drug Delivery Devices
The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in order to fabricate physical models based on a computer aided design (CAD) model. 3D printing permits the fabrication of high degrees of complexity with great reproducibility in a fast and cost-effective fashion. 3DP technology offers a new paradigm for the direct manufacture of individual dosage forms and has the potential to allow for variations in size and geometry as well as control dose and release behavior. Furthermore, the low cost and ease of use of 3DP systems means that the possibility of manufacturing medicines and medical devices at the point of dispensing or at the point of use could become a reality. 3DP thus offers the perfect innovative manufacturing route to address the critical capability gap that hinders the widespread exploitation of personalized medicines for molecules that are currently not easy to deliver. This Special Issue will address new developments in the area of 3D printing and bioprinting for drug delivery applications, covering the recent advantages and future directions of additive manufacturing for pharmaceutical products.
Chemical and Structural Approaches to Rational Drug Design
This book deals with predominantly synthetic chemical approaches to drug design and explores the use of structure-activity relationships in the design of novel inhibitors of ribonucleotide reductase. It describes the application of the tools of structural biology to pharmaceutical development.
Chronic Pain
Chronic Pain: Assessment, Diagnosis, and Management focuses on conquering pain and its related problems through proper management. It offers numerous tools and concepts with which to attack chronic pain and win the battle that more than 35 million people in the U.S. alone fight every day. Virtually all specialists in the health care field must be c
PsychofonieH繹re den grossen Gesang in Dir
Heilung beginnt im Kopf. Diese Binsenwahrheit ist auch in der westlichen Medizin angekommen. Yoga, Meditation, Hypnose, Biofeedback, Psychotherapie, Musiktherapie, progressive Muskelentspannung und verschiedene Aktivierungs- und Bewegungstherapien sind in aller Munde, wenn es gilt, chronische Leiden zu behandeln. All diese Kuren sind personalintensiv und sehr zeitraubend. Psychofonie hat von allen diesen Methoden etwas und ist doch grundlegend anders. Mit Psychofonie machst Du im Jahr 1000 Mini-Sitzungen, die sich perfekt in Dein Leben einbauen lassen, als kurze Besinnungspausen. Das ist an sich schon heilsam. Aber es sind Pausen in einem erweiterten Sinn, Du musst nichts tun - nur h繹ren. Zehn Minuten mit Kopfh繹rer gen羹gt. Das Bild auf der Vorderseite des Buches bringt es auf den Punkt: Du singst in diesen Pausen mit Dir selbst. Aber nicht auf der Ebene der Sprache, sondern auf der unbewusst vegetativen Ebene der Hirnfunktion. Die St繹rung, die Dich plagt und die wir mit Kl瓣ngen zum Verschwinden bringen, sitzt in jedem Fall mitten in Deinem Gehirn. Im Thalamus befindet sich eine Art Orchester. Die chronischen Schmerzen und Leiden sind in diesem wunderbaren Klanggebilde als falsche Musikanten und S瓣nger repr瓣sentiert. Es ist m繹glich, ihr Spiel mittels Elektroenzephalogramm h繹rbar zu machen. Das EEG ist der messbare dynamische Ausdruck Deiner momentanen Verfassung. Wir nehmen es au?en am Kopf in einem Zustand des Wohlbefindens bei Dir einmal ab und wandeln es mathematisch in Klangfolgen um. Ab dann hast Du die Psychofonie als eine auf Dich abgestimmte pers繹nliche Heilmusik immer dabei. Dieses Buch zeigt Dir, wie das funktioniert, wie es fachgerecht getestet wurde, wie man es anwendet und was man erwarten darf. Es zeigt den Nutzen bei Kopfschmerzen, Migr瓣ne, Schlafst繹rung, ADS, Tinnitus, Traumata und Stress. Und es macht Dir das enorme Heilpotenzial der Psychofonie durch zahlreiche Fallberichte eindr羹cklich klar.
OPEN UP statt ShutdownSpagyrische Mischungen, die uns 繹ffnen f羹r die F羹lle
Angesichts der einschneidenden Ver瓣nderungen, die die Corona-Krise 2020 mit sich bringt, sehen viele einer unsicheren Zukunft entgegen. Was diese uns bringt, haben wir nicht in der Hand. Es liegt aber an uns, mit welcher inneren Haltung wir den Ver瓣nderungen begegnen. Die Mischungen in diesem Buch sind Wegbereiter. Sie unterst羹tzen uns, alte Begrenzungen hinter uns zu lassen und 繹ffnen uns f羹r die F羹lle unserer M繹glichkeiten. M繹ge das Buch uns einen positiven Blick auf unsere Zukunft schenken.
Handbook for HomoeopathyDigestive Tract Remedies
Gives a brief introduction of Homoeopathy on things like, basics of Homoeopathy, principles of diagnosis, physiology of digestive tract, and its treatment. This book makes you familiar with key concepts of digestive tract with respective Homoeopathy and keeps you informed, like being guided by a Homoeopath. Explains process of digestion, common ailments, and treatment by symptoms (Mouth-Inflammation Acute and chronic Pharyngitis, Stomach-Acute & Chronic Gastritis)Addresses treatment for abdomen and liver Inflammation caused by Gastro Enteritis, Inflammation in liver caused by gall stones and Gallbladder ailments.Treatment explained for aliments like peptic ulcers, piles, anal inflammation, and gas accumulation.
Ayurvedic Diet for Weight Loss
Ayurvedic dieting is all about eating and eating well. Weight gain is not because of how much we eat it is about how much of what we eat. This is exactly the problem that ayurvedic diet addresses through its core tenets. Through this eBook I have tried to build a relation between nature and food through the principles of Ayurveda that not only helps in healthy weight loss but also focuses on holistic well-being. I have used tips and basic knowledge to educate you about this diet form so that you can make an informed choice equipped with all the core information that forms the basis of Ayurvedic dieting.
The Constituents of Medicinal Plants
An easy to understand introduction to the organic chemistry of medicinal plants
GMP in Pharmaceutical Industry
This handbook has been written for the students of pharmacy and pharmaceutical industry. It gives pocket guide of good manufacturing practices in pharmaceutical industry. The purpose of this handbook is to provide easily accessible knowledge about the pharmaceutical industry and to assist individuals to know about pharmaceutical world.This handbook has also incorporated the current trends and expectations of the evolving pharmaceutical industry and regulatory oversight.In current pharmaceutical world we need a fast and reliable source of techniques to implement the system and resolve problem. This handbook gives pathway for us to take right decision. Nothing comes in a one box for us. Changes happen with or without us. The higher we go in the organization, the more complex our challenges become. This book gives overall view of quality management systemWe hope this handbook can contribute to assemble lots of related materials and package them in one place for easy reference and access.I encourage you to read, enjoy, study, and learn from this book, and go forth and empower your teams to lead you and your organization to world class results
The Drug Recognition Guide
The Drug Recognition Guide introduces an innovative method for recognising and categorising medications, enabling readers to easily identify the type and use of a generic drug by visually deconstructing its name. Through its creative use of colour-coded drug prefixes and suffixes, this pocket-sized guide makes generic drug names distinctive, logical, and easy to pronounce and remember. More than 700 drugs from over 200 different drug categories are catalogued and colour-highlighted--helping you understand what underlies a generic drug name. Organised by class and use, the book's ten chapters cover a comprehensive range of drugs, including chemotherapy and immunosuppressants, drugs that affect the cardiovascular and respiratory systems, drugs used to manage pain, treat infectious diseases, and many others. Each entry briefly summarises a particular class of drugs, describes the intended use of drugs within the class, and breaks down the "name stems" of individual drugs to reveal useful information and illustrate connections between chemically and therapeutically related medicines. Presenting an original, easy-to-use approach to the complex subject of drug classification, this invaluable learning aid: Provides a thorough yet accessible way for students and practitioners to increase their understanding of medications and their application Helps students to clearly read and pronounce even the most difficult generic drug names Highlights the letters in generic drug names to enable students to recognise drugs immediately Explains who assigns a generic drug name and what the name represents Includes an introduction to generic and proprietary drug names and design motifs The Drug Recognition Guide is essential reading for nursing and medical students, pharmacy students and technicians, as well as nurse practitioners and trainee and junior doctors.
Acupuncture and Infrared Imaging
The Chinese acupuncturists use needles to treat at least one hundred fifty kind diseases with successes for thousands of years on more than one billion people with remarkable success.But it has not been accepted by the main stream Western medicine, and taught in main stream medical school. Probably it is due to two factors: theoretically it has not been explained by modern science, and second there is no quantitative objective evidence for it. This book answers these two questions. It provides modern scientific explanation to important concepts, especially meridians and qi. What are meridians made up of? What are acupoints? What is qi? Can they be seen? This book presents copious pictures taken by infrared images method. They provide the objective evidence how acupuncture works, what are meridians made up of, and what is the measurable effect of qi. Each thermograph has more than ten thousand pixels. Each pixel is associated with one temperature to the accuracy of 0.1 0 C. So the science of acupuncture becomes a quantitative science with enormous accurate numbers as supporting evidence. This book contains twenty nine easy to read articles, which cover many important topics in acupuncture and Chinese medicine. Each essay has at least one infrared image, So the reader can see the images for himself, and understand that there are incredible accurate data supporting acupuncture and Chinese medicine.
