![The Chemist and Druggist [electronic Resource]; Vol. 121 = no. 2859 (24 Nov. 1934)](https://cdn.kingstone.com.tw/english/images/product/1001/9781014461001m.webp "The Chemist and Druggist [electronic Resource]; Vol. 121 = no. 2859 (24 Nov. 1934)")
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Touching the Hidden You
SYNOPSISIn Touching the Hidden You, Ricardo J. F. Dias presents us with a bold, controversial and polemical therapeutic approach, challenging us to question the concepts of life, health and disease. Contextualizing his personal and professional path, he introduces us to the key moments that changed his life and that made him rethink the concepts of health and illness, moving from something predictable to something extraordinary. He presents us with a selection of cases that he followed, which illustrate that illness does not always have a physical origin and that there are forms of treatment that will certainly impress you. Throughout his narrative, we find questions to reflect on, as well as suggestions for additional information. Easy to read, the material in the book is the result of the author's vast experience in the field of manual therapy, but mostly of the last 11 years, in which he has dedicated himself to developing a therapy based on touch, body symbolism and hypnosis, to treat not only the body, but also the emotions, the mind and the spirit. The book is focused on the concept of "parts" and it is in this context that topics such as consciousness and not consciousness, emotions, memories, repetitive cycles, psychogenealogy, exorcism, past lives, spiritism and many others are discussed. Discover what these parts are or who they are and how they communicate and allow you to perform, for example, physical treatments at a distance, just with your thought. ABOUT THE AUTHORRICARDO J. F. DIAS is a rehabilitation nurse, osteopath and trainer of health professionals and of alternative and complementary medicine therapists. His passion is manual therapy, having developed, over the past 11 years, his own concept of therapy, working with body symbolism for physical, emotional, mental and spiritual treatment. Among his training, the master's degree in sports sciences, coaching and the neurolinguistic programming master stand out. In addition to his participation as a speaker in health and in alternative and complementary medicine congresses, his professional career includes 18 years of hospital experience and sports, as a nurse, 15 years as a vocational trainer, 11 years as an osteopath and as a life coach and 9 years as a manager of a health training company. He is from Porto, Portugal, and it is through physical activity that he charges his energy. He is a fan of bicycle trips, with bags, and long walks, especially on the Santiago's Way or "The Way of Saint James". CONTACTSYou can find him at: Website: www.touchingthehiddenyou.wordpress.comEmail: touchingthehiddenyou@gmail.comFacebook: touchingthehiddenyouInstagram: touchingthehiddenyouGoodreads: goodreads.com/ricardojfdias
The Age of Fentanyl
Ottawa Book Award 2021 -- Shortlisted - The Donner Prize 2020 -- Shortlisted - Speaker's Book Award 2020 -- Shortlisted Is there a way to end North America's opioid epidemic?"A fascinating, wise, and humane analysis of one of the most pressing health challenges of the 21st century." -- Steven Pinker, author of Enlightenment NowIn The Age of Fentanyl, Brodie Ramin tells the story of the opioid crisis, showing us the disease and cure from his perspective as an addiction doctor working on the front lines. We meet his patients, hear from other addiction experts, and learn about the science and medicine of opioid addiction and its treatments. He shows us how addiction can be prevented, how knowledge can reduce stigma, and how epidemics can be beaten.Dr. Ramin brings the hopeful message that just as patients and health care workers rallied together to fight HIV one generation ago, a coalition of patients, advocates, scientists, doctors, and nurses is once again finding solutions and making plans to stem the overdose deaths, block the spread of fentanyl, and end the epidemic.
Chronic Rhinosinusitis and Concomitant Medical Disorders
It is with great pleasure that we present to you this Special Issue of Medical Sciences. In this issue, we present a comprehensive and contemporary review of the medical comorbidities that contribute to chronic rhinosinusitis, and, conversely, how our interventions as otolaryngologists can impact those systemic conditions. Our understanding of chronic rhinosinusitis has evolved tremendously over the last two decades. As we have learned, chronic rhinosinusitis--a chronic inflammatory condition of the nasal cavity and paranasal sinuses--is often a local inflammatory response to a systemic or mucosal disorder. The underlying systemic medical conditions not only influence the presentation and diagnosis of chronic rhinosinusitis, but also modify the patients' response to medical and surgical interventions. Chronic rhinosinusitis associated with cystic fibrosis, for example, is a disorder quite distinct from that associated with aspirin-exacerbated respiratory disease. A clear understanding of the nuances that distinguish these unique and challenging disorders is critical for the practicing otolaryngologist. Equally important, however, is a clear understanding of the powerful benefits that our interventions as otolaryngologists can have for our patients' rhinologic and systemic health. Knowing that our rhinologic interventions might spare an asthma patient a trip to an emergency room or reduce lung infections in a cystic fibrosis patient makes this a very exciting time to be a rhinologist. We hope you enjoy this Special Issue of Medical Sciences.
Wechselbeziehungen zwischen dem psycho-physischen Funktionszustand des Organismus und dem
Masterarbeit aus dem Jahr 2011 im Fachbereich Medizin - Alternative Medizin, Note: 1,0, FH Gesundheit Tirol (fhg - Zentrum f羹r Gesundheitsberufe Tirol GmbH), Sprache: Deutsch, Abstract: In der Osteopathie wird die autonome Funktion durch Palpation von K繹rperrhythmen z.B. am Sch瓣del beurteilt. Ziel dieser Studie ist es, herauszufinden, ob die ger瓣tegest羹tzte und manuelle Diagnostik vergleichbare Ergebnisse bez羹glich der autonomen Funktion liefert, um die osteopathische Methode wissenschaftlich zu unterlegen. Konzeptionell handelt es sich um eine nicht-interventionelle Diagnosestudie mit Vergleich zweier Methoden zur Beurteilung der G羹te einer diagnostischen Methode (Craniosakrale Palpation) im Vergleich zu einer schulmedizinischen Methode (Herzfrequenzvariabilit瓣tspr羹fung). Im ersten Abschnitt der theoretischen Grundlagen wird zun瓣chst ein historischer ?berblick 羹ber osteopathische Prinzipien, biologische Rhythmen und vorliegende Studien mit vergleichbarer Fragestellung gegeben. Nach einer funktionellen Darstellung des autonomen Nervensystems folgt eine anatomische ?bersicht des ANS gegliedert von der obersten Ebene im Gehirn, der mittleren Ebene auf R羹ckenmarkh繹he und der unteren Ebene im peripheren System der Nerven zu den Endorganen. Anschlie?end werden im Hauptteil verschiedene Reflexsysteme besprochen, die sich in der HFV abbilden und auch als Grundlage des Craniosakralen Rhythmus diskutiert werden. Im methodischen Teil wird gepr羹ft, ob sich der Craniosakrale Rhythmus der Osteopathischen Medizin in schulmedizinisch bekannten, oszillierenden Systemen widerspiegelt und zur Beurteilung der autonomen Funktion herangezogen werden kann.
New Insights into Parvovirus Research
Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus-cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus-host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.
Treatment Strategies and Survival Outcomes in Breast Cancer
Treatment strategies for breast cancer are wide-ranging and often based on a multi-modality approach, depending on the stage and biology of the tumour and the acceptance and tolerance of the patient. They may include surgery, radiotherapy, and systemic therapy (endocrine therapy, chemotherapy, and targeted therapy). Advances in technologies such as oncoplastic surgery, radiation planning and delivery, and genomics, and the development of novel systemic therapy agents alongside their evaluation in ongoing clinical trials continue to strive for improvements in outcomes. In this Special Issue, we publish a collection of studies looking at all forms of therapeutic strategies for early and advanced breast cancer, focusing on their outcomes, notably survival.
Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery
Mucoadhesive polymers are widely used in the design of dosage forms for transmucosal drug delivery to the eye, respiratory, gastrointestinal and reproductive tracts. These routes of drug administration offer a number of advantages including improved drug bioavailability, reduced frequency of administration, and the avoidance for the use of injections. This book represents a collection of reviews and original research articles in the area of mucoadhesive polymers and dosage forms. It covers the design of mucoadhesive forms from commercially-available water-soluble polymers, their mixture and complexes as well as some materials, whose mucoadhesive properties were enhanced through chemical modification. With contributions from leading experts in mucoadhesive polymers and formulations, this book will be a very useful source of information for researchers in polymer, pharmaceutical and formulation sciences.
Roles and Functions of ROS and RNS in Cellular Physiology and Pathology
Our common knowledge on oxidative stress has evolved substantially over the years and has been mostly focused on the fundamental chemical reactions and the most relevant chemical species involved in the human pathophysiology of oxidative stress-associated diseases. Thus, reactive oxygen species and reactive nitrogen species (ROS and RNS) were identified as the key players initiating, mediating, and regulating the cellular and biochemical complexity of oxidative stress either as physiological (acting pro-hormetic) or as pathogenic (causing destructive vicious circle) process. The papers published in this particular Special Issue of the Cells demonstrate the impressive pathophysiological relevance of ROS and RNS in a range of contexts, including the relevance of second messengers of free radicals like 4-hydroxynonenal, allowing us to assume that even more detailed mechanisms of their positive and negative effects lie in wait, and should assist in better monitoring of the major modern diseases and the development of advanced integrative biomedicine treatments.
Adipokines 2.0
Once viewed solely as fat storage cells, adipocytes and their adipokines have now been proven to be central for human health. Understanding that overweight and obesity may increase the risk for various diseases requires detailed characterization of adipokine function. Weight gain, weight regain, and fasting affect adipocyte health and accordingly their secretome. Different adipose tissue deposits exist and they vary in cellular composition and function. The evidence is strong of a role of adipokines in cancer, reproductive function, neurological diseases, cardiovascular diseases, and rheumatoid arthritis. Adipokines are considered useful biomarkers for adipose tissue and metabolic health, and may be used as diagnostic tools in rheumatoid arthritis, cancer, or sepsis. This book contains 10 original articles and 9 review articles focusing on these bioactive peptides. Several articles deal with chemerin, an adipokine discovered more than 20 years ago. Data so far have resulted in promising insights related to its biological function. We are only beginning to understand the multiple roles of chemerin, the mechanisms regulating its activity, and the signaling pathways used by this chemokine. Adipokine receptor agonists and antagonists may result in the formulation of novel drugs and ultimately may lead to new therapeutic targets to be used in clinical practice.
Informationsmedizin
Wir erleben zurzeit eine wissenschaftliche Revolution. Ziel dieses Buches ist es u.a. diese Ver瓣nderungen und ihre Auswirkungen auf die praktische T瓣tigkeit von ?rzten und Therapeuten darzustellen. Der Begriff Bioinformation ist ein neues Schlagwort geworden. Es ist schon so allt瓣glich, dass von vielen alternativmedizinischen Ger瓣ten (angeblich) digitalisierte Bioinformation f羹r Diagnose und Therapie verwendet werden kann. Der Nutzen liegt auf der Hand. Das digitale Bio-Korrelat ist praktisch unzerst繹bar, in unvorstellbar gro?er Zahl auf denkbar kleiner Fl瓣che (PC-Hard Disk) archivierbar, ver瓣ndert sich nicht, kann diagnostisch und therapeutisch 瓣u?erst bequem in Kombination allein eingesetzt werden.
The DNA Diet
HOW TO "HACK" YOUR GENESDid you know that you can change your genes?Did you know that your own emotions influence your genes?Have you noticed that there are families in which one brother stays slim, no matter what he eats, while the other brother constantly has trouble maintaining his weigh?--------------------------------------------------------------------------------Classic nutrition focuses on macro-nutrients (carbohydrates, fats and proteins) and micro-nutrients (vitamins and minerals) as the most important elements to consider in alimentation without taking into account the bio-active components of foods such as antioxidants, co-enzymes, phytonutrients, and others. Yet these components contain the elements which give strength to and modify our DNA.--------------------------------------------------------------------------------With The DNA Diet, you will understand terms such as: nutrigenomics, nutrigenetics, and epigenetics. And you will understand how these terms affect your life. With this book, you will learn how to develop strategies for your alimentation and lifestyle that allow you to consciously "hack" your genes and take them to their best possible version. You will also know: -The best foods for you-Genetic strategies to "hack" your genes and slow aging-The genetic benefits of meditation-The genetic benefits of exercise-Scientifically-proven natural treatments which allow you to strengthen your health-If you already have an illness, learn scientifically-proven natural treatments which allow you to recover your health.--------------------------------------------------------------------------------We have all heard the saying, "you are what you eat", but with The DNA Diet we take it to the next level, showing you what The Age of Ultra-personalized Medicine has prepared for you.For more information visit: www.centrogenica.com
Self－Organizing Nanovectors for Drug Delivery
Nanomedicine represents one of the most investigated areas in the last two decades in the field of pharmaceutics. Several nanovectors have been developed and a growing number of products have been approved. It is well known that many biomaterials are able to self-organize under controlled conditions giving rise nanostructures. Polymers, lipids, inorganic materials, peptides and proteins, and surfactants are examples of such biomaterials and the self-assembling property can be exploited to design nanovectors that are useful for drug delivery. The self-organization of nanostructures is an attractive approach to preparing nanovectors, avoiding complex and high-energy-consuming preparation methods, and, in some cases, facilitating drug loading procedures. Moreover, preparations based on these biocompatible and pharmaceutical grade biomaterials allow an easy transfer from the lab to the industrial scale. This book reports ten different works, and a review, aiming to cover multiple strategies and pharmaceutical applications in the field of self-organizing nanovectors for drug delivery.
Natural Products and Drug Discovery
Natural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays.
Kidney Inflammation, Injury and Regeneration
Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.
Arthropod Venom Components and Their Potential Usage
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods' venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC-MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Synthetic and Biosynthetic Approaches to Marine Natural Products
Marine natural products containing a heterocyclic moiety in their structure are present in a wide variety of sponges, corals, algae, and fungi. Many of them show important biological activities such as cytotoxic properties against several cancer cell lines. Their challenging chemical structures have attracted the attention of many researchers who have developed various synthetic approaches. This Special Issue presents some examples of new synthetic or biosynthetic methodologies to access this type of marine natural drug.
Manual Dmso Para M矇dicos
DMSO, un verdadero principio medicamentoso El DMSO es un compuesto qu穩mico natural proveniente de la pulpa de los 獺rboles, producto de la manufactura de papel. Es un nuevo principio m矇dico y le llaman el medicamento milagro. Se ha probado su eficacia, tanto solo como combinado con otras sustancias, en el tratamiento de casi todas las enfermedades conocidas. Aunque ha provocado muchas controversias durante los 繳ltimos cincuenta a簽os, el DMSO es uno de los productos m矇dicos m獺s estudiados por la ciencia. Cuando se utiliza de manera adecuada, es tambi矇n una de las sustancias m獺s seguras que existen. Este manual provee la informaci籀n necesaria para argumentar que el DMSO es posiblemente el producto m獺s vers獺til que existe para aliviar el sufrimiento de los seres humanos. Archie es sin lugar a dudas una autoridad en el mundo del DMSO por su gran conocimiento sobra los beneficios m矇dicos de esta sustancia. Durante d矇cadas, 矇l ha estudiado y trabajado con el DMSO. Conoce su utilidad, su eficacia y su seguridad. Recomiendo este manual para cualquier trabajador de la salud, especialmente a quienes quieren aprender sobre terapias m矇dicas no t籀xicas. El DMSO es muy beneficioso para todos los que sufren. Dr. Daniel Junck
Az繳car
En este libro, en primer lugar, se hace una descripci籀n sucinta de las principales enfermedades relacionadas con el consumo excesivo de hidratos de carbono (carbohidratos) seg繳n la dieta actual, como la obesidad, la diabetes, las alteraciones cardiovasculares, las afecciones neurol籀gicas y la desmineralizaci籀n. Despu矇s se centra en c籀mo estos alimentos representan un riesgo importante de contraer cualquier tipo de c獺ncer. Es un hecho reconocido que el az繳car y los hidratos de carbono no son sustancias cancer穩genas, pero en cambio son un alimento para las c矇lulas cancerosas y lo hacen de 5 maneras diferentes. Finalmente se dan unos consejos para llevar una vida saludable y reducir el riesgo de c獺ncer. AUTOR: AURELIO ZAMORA RODR?GUEZ, es Licenciado en Ciencias Qu穩micas. Reci矇n terminada la Carrera ingres籀 en el Departamento de Investigaci籀n del Instituto de Biolog穩a y Sueroterapia (IBYS) en Madrid, dedicado a la investigaci籀n en el campo de la Inmunidad. Despu矇s de unos a簽os se traslad籀 a Alemania para estudiar nuevas t矇cnicas en este campo, y que continu籀 a su regreso a Espa簽a en el mismo Instituto IBYS. Trabaj籀 tambi矇n en otro Laboratorio Farmac矇utico donde elabor籀 un f獺rmaco a base de silimarina, obtenida del cardo mariano para el tratamiento de enfermedades hep獺ticas, siendo el primer laboratorio espa簽ol en comercializarlo. Otro campo al que se ha dedicado es al de vitaminas y minerales, sobre todo el calcio y el magnesio. Los 繳ltimos a簽os de su vida laboral los ha realizado en una Empresa de Alimentaci籀n, dirigiendo el Departamento de Investigaci籀n y Desarrollo. Ha publicado en revistas diversos art穩culos de divulgaci籀n sobre nutrici籀n y alimentaci籀n. Es miembro em矇rito de la Real Sociedad Espa簽ola de Qu穩mica. ILUSTRACIONES: ?SCAR ZAMORA BERG?S (Auxiliar de Enfermer穩a y Fitoterapeuta).
Meine Ersten beiden Unterrichts-Stunden in Qigong Yangsheng als Kursleiter in Ausbildung
Projektarbeit aus dem Jahr 2019 im Fachbereich Medizin - Alternative Medizin, Note: keine, Veranstaltung: mind. 2-j瓣hrige Grundausbildung - Ausbildung zum Qigong-Kursleiter (Lehrsystem Qigong Yangsheng nach Prof. Jiao Guorui), Sprache: Deutsch, Abstract: Das Thema des hiermit vorgelegten ersten Erfahrungsberichtes dokumentiert und reflektiert meine ersten beiden Qigong Yangsheng Unterrichts-Einheiten als Kursleiter in Ausbildung, die - so viel sei hier schon verraten - im Rahmen meiner Grundausbildung m.E. verh瓣ltnism瓣?ig fr羹h, zudem ziemlich 羹berraschend und im wahrsten Sinne des Wortes irgendwie einfach so "auf mich zukamen". Dieser Erfahrungsbericht ist folgenderma?en strukturiert: Nachdem in Kapitel 2 羹ber die Schilderung meiner pers繹nlichen Ausgangslage eine Einf羹hrung in die Themenstellung erfolgt, werden dann in Kapitel 3 in einer kritischen Selbst-Reflexion meine eigenen, ganz pers繹nlichen, Erfahrungen vor, w瓣hrend und nach meinen ersten beiden Qigong Yangsheng ?bungs-Einheiten "'vor' statt 'in' einer Gruppe" dargestellt. Abschlie?end soll dann in Kapitel 4 noch eine kurze Bewertung, W羹rdigung sowie ein perspektivischer Ausblick vorgenommen werden.
How Can Traditional Ethopian Medicine Help Against Diarrhea? Antidiarrheal and Antispasmodic Avtivities of Stephania Abyssinica (Minispermaseae)
Master's Thesis from the year 2010 in the subject Medicine - Pharmacology, Pharmacy, grade: Very Good, Addis Ababa University (SCHOOL OF GRADUATE STUDIES), language: English, abstract: Diarrhea is a leading cause of morbidity and mortality in developing countries. The aim of this work was therefore to evaluate the antidiarrheal and antispasmodic activities ofthe aqueous and methanol extract of the root and leaf of S. abyssinica. Antidiarrheal activities were studied in mice using castor oil-induced diarrhea at doses of 25, 50,100, and 200 mg/kg body weight. The extracts significantly prolonged the time of diarrheal induction, increased diarrhea free time, reduced the frequency of diarrhea episodes, decreased the weight of stool, and decreased general diarrheal score in a dose dependent way. With dose of 200 mg/kg the extracts produced higher in-vivo antidiarrheal index (ADI) than the the standard loperamide. In Entropooling test in mice the extract significantly (p
Instrumental Methods of Drug Analysis
The book is conveniently divided into several chapters, each chapter dealing with a method of instrumental analysis. The book gives a review of several conventional methods like UV, Visible and Flourimetric Spectroscopy and also deals at length, the newer techniques like HPLC, quality evaluation of Herbals etc. The book is also useful to Analysts, and Quality Control staff of Pharmaceutical Industry.Main highlight: - Topics have been written in easy to understand and simple language with special emphasis on Pharmaceutical applications.
Soft and Hard Tissue Regeneration
This special issue entitled "Soft and hard tissue regeneration" will cover both periodontal and implant therapies. Regenerative periodontal treatment goal is to restore functional periodontal support offering a valuable treatment alternative even for teeth with large periodontal destruction, which may be successfully treated and maintained in health for long periods. In most cases where teeth are extracted for periodontal reasons, implant therapy will demand large bone augmentation procedures. Lack of sufficient bone volume may prevent placement of dental implants. In extreme cases, large bone reconstruction is indispensable before implant placement can be performed. Although, most bone grafts are only able to fill and maintain a space, where bone regeneration can occur ("osseoconductive"), the ideal bone graft will also promote osseous regeneration ("osseoinductive"). Several bone augmentation procedures have been described, each, presenting advantages and shortcomings. Success of bone augmentation procedures depends on the presence of bone forming cells, primary wound closure over the augmented area, space creation and maintenance where bone can grow and proper angiogenesis of the grafted area. Factors that influence the choice of the surgical technique are the estimated duration of surgical procedure, its complexity, cost, total estimated length of procedure until the final rehabilitations may be installed and the surgeons' experience. This special issue will have a definite clinical orientation, and be entirely dedicated to soft and hard tissue regenerative treatment alternatives, both in periodontal and implant therapy, discussing their rationale, indications and clinical procedures. Internationally renowned leading researchers and clinicians will contribute with articles in their field of expertize.
Wie verh瓣lt sich das vegetative System in der Herzratenvariabilit瓣t bei Akupunktur?Traditi
Masterarbeit aus dem Jahr 2016 im Fachbereich Medizin - Alternative Medizin, Note: 2,0, Technische Universit瓣t M羹nchen (Fakult瓣t f羹r Sport- und Gesundheitswissenschaften), Sprache: Deutsch, Abstract: Ziel der Pilotstudie war die Untersuchung der Wirkung von K繹rperakupunktur auf das vegetative System. In einer Praxis f羹r Traditionelle Chinesische Medizin wurde im Laufe eines halben Jahres w瓣hrend der Akupunkturbehandlungen die Herzratenvariabilit瓣t HRV als Kurzzeitvariabilit瓣t gemessen. In der Sportmedizin und in den Trainingswissenschaften werden auch bei Gesunden Auswirkungen von k繹rperlichen Belastungen und die Erholungsf瓣higkeit 羹ber Messung des autonomen Nervensystems mittels Herzratenvariabilit瓣t (HRV) beurteilt. Als Grundlage dieser Messungen werden biologische Rhythmen verschiedener Funktionskreise erfasst. Diese sind durch Oszillationen gekennzeichnet, deren Rhythmen unterschiedliche Periodendauern haben. Wissenschaften wie die Chronobiologie und Chronomedizin besch瓣ftigen sich mit den Arten biologischer Rhythmen, der anatomischen Lokalisation und der Funktion biologischer Oszillatoren. St繹rungen dieser biologischen Rhythmen werden h瓣ufig angetroffen. Hierzu tragen eine Reiz羹berflutung durch stundenlange T瓣tigkeit am PC, Schichtarbeit, Fehlern瓣hrung, lange Autofahrten, Bewegungsmangel, h瓣ufige Interkontinentalfl羹ge etc. bei. In dieser Pilotstudie soll die Wirkung von K繹rperakupunktur auf das autonome Nervensystem untersucht werden. An PatientInnen, die 羹berwiegend mit orthop瓣dischen Beschwerden zur Therapie kommen, wird w瓣hrend der Akupunkturbehandlungen die HRV gemessen. Dabei soll herausgefunden werden, ob sich Effekte auf das autonome Nervensystem ergeben und ob diese einer Systematik folgen. In der klinischen Studie, die als L瓣ngsschnittstudie 羹ber sechs Monate konzipiert ist, erfolgt die Auswahl der PatientInnen nicht zufallsorientiert. Die Therapieintervalle richten sich nach den Grunderkrankungen und werden f羹r die Studie nicht ge瓣ndert. Im erste
Enhancement of solubility and dissolution rate of Griseofulvin
In the recent years, the interest in micron and submicron systems in pharmacy as surged. Micron system comes in range of μm and submicron in nm. Typically colloid is an intermediates size between molecular range and coarse range. There has been a considerable research interest in the area of drug delivery using particulate systems. Particulate systems used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. Griseofulvin is an important agent in the treatment of dermatophytosis. Results of present work lead to a conclusion that reduced size of the drug particles with presence of the surfactants and polymers on the surface of griseofulvin microparticles are responsible for meteoric rise in solubility and dissolution velocity. Surfactants play an important role in the solubility of the drugs by increasing the wettability due to adsorption on the surfaces. Microparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules due to increased surface area by several times.
Surgery for Spine Disease and Intractable Pain
This book describes the diagnosis and surgical treatment approaches for a number of common and rare painful conditions affecting the brain and spine.
Biomedical Insights that Inform the Diagnosis of ME/CFS
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe chronic health condition that is often misunderstood or ignored by health establishments. The lack of definitive diagnostic markers to separate ME/CFS patients from the healthy population as well as from other chronic disorders is problematic for both health professionals and researchers. A consortium of Australian researchers gathered to systematically understand ME/CFS, ranging from a deep analysis of clinical and pathology data to metabolomic profiles and the investigation of mitochondrial function. From this broad collaboration, a number of compelling insights have arisen that may form the basis of specific serum, blood, and/or urinary biomarkers of ME/CFS. This Special Edition reports on a conference centred on these biomedical discoveries, with other contributions, with a translation focus for predictive markers for ME/CFS diagnosis. By supporting health professionals with developments in diagnostics for this condition, the patients and their families will hopefully benefit from an improved recognition of the biomedical underpinnings of the condition and will be better able to access the care that is urgently required. This Special Edition contains a mix of speaker submissions and other accepted manuscripts that contributed to our objective of advancing biomedical insights to enable the accurate diagnosis of ME/CFS.
Recent Development of Electrospinning for Drug Delivery
Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline-amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical-chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.
Gastrointestinal Variables and Drug Absorption
This book presents some of the state-of-the-art methods for the study of the gastrointestinal variables affecting oral drug absorption. Practical applications of new in vitro release/dissolution methods are presented, as well as in vitro permeability studies to explore segmental differences. The application of MRI methods for the study of colon physiology is presented to illustrate its potential applications in controlled release dosage form design. Some examples of successful in vitro-in vivo correlations show how implementing the gastrointestinal physiological variables in the new in vitro methods can improve the predictions of in vivo drug product performance. The book contains an updated review of the experimental, computational, and in vivo approaches for measuring intestinal permeability.
Magnetic Nanoparticles
The present book covers all research areas related to magnetic nanoparticles, magnetic nanorods, and other magnetic nanospecies, their preparation, characterization, and various applications, specifically emphasizing biomedical applications. The chapters written by the leading experts cover different subareas of the science and technology related to various magnetic nanospecies--providing broad coverage of this multifaceted area and its applications. The different topics addressed in this book will be of great interest to the interdisciplinary community active in the area of nanoscience and nanotechnology. It is hoped that this collection and its various chapters will be important and beneficial for researchers and students working in various areas related to bionanotechnology, materials science, biosensor applications, medicine, and many others. Furthermore, this book is aimed at attracting young scientists and introducing them to this field, in addition to providing newcomers with an enormous collection of literature references.
Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery
Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development.
Hom繹opathie und...Undinen und Leviathane
Es sind ganz offensichtlich tiefe seelische Strukturen, denen die in diesem Band versammelten Geschichten entsprungen sind. F羹r die Autoren ist das der Grund, sich diese Geschichten vom psychodynamischen und hom繹opathischen Blickwinkel her anzusehen. Die Autorin und der Autor gehen dieses Vorhaben teilweise recht unterschiedlich an, meinen aber, dass sich diese verschiedenen Herangehensweisen sehr gut erg瓣nzen. Das Buch ist sowohl f羹r Hom繹opathen und Psychologen/Psychotherapeuten als auch f羹r interessierte Laien gedacht.
Acupuncture and Cellular Molecular Biology
This book explains the basic theory for the therapy and anesthesia by acupuncture. At first author put forward the principle that Meridian is the bio-wave tunnel in human body which is produced by the interaction between earth magnetic field and the electric current of the pules from heart and central nerve system in human body. Author appoints meridian is not tissue of anatomy of human body.
Anti－Photoagaing and Photo－Protective Compounds from Marine Organisms
This Special Issue Book "Anti-Photoagaing and Photo-Protective Compounds from Marine Organisms" is aimed at collecting literature on the below-mentioned keyword topics, which can significantly increase our basic understanding of marine-derived compounds in cosmeceutical product development and increases the value of marine products at the industrial level.
Bio-Energy Self Treatments
Bio-Energy Self Treatments (BEST) is an alternative medical therapy book. It is very simple to perform and has no cost. It is an advanced touch therapy method. Bio-energy is the natural energy in our body by which our internal organs function. This treatment is for self-use and to treat others for any disease.- Five Elements- Internal Organs- Pulse Diagnosis- Bio-Energy Self Treatments- Emergency Treatments (like Faint, BP, Heart Attack)- The Pain Treatments for the Head and Extremities (Hands and Legs)- Few Diseases and their Treatments (for Reference)This book explains the aforementioned topics in a simple and clear way.
Pharmacist 101
If you want to learn how to become a pharmacist, then get this "Pharmacist 101" guide today! In Pharmacist 101, you will learn these top lessons from a real pharmacist. - Evaluation of the real pharmacy lifestyle - Broken down into sections for before pharmacy school, during pharmacy school, during rotations, and after graduation - Additional chapters on finance and extra reading suggestions - Expanded lesson on surprising areas within the field of pharmacy that pharmacists can be found o Open discussion of benefits and struggles within each subcategory o A day in the life of a hospital pharmacist - Step-by-step description of application process for getting into pharmacy school - Step-by-step description of process for taking pharmacy board exams and obtaining licensure after graduation - The real value of experience before and during pharmacy school - General guidelines for conducting yourself on rotations - Tips to establish solid professional relationships - Discussion of critical classes within the pharmacy curriculum - Considerations for elective courses in pharmacy school - Information about continuing education requirements after graduation - How to handle and prevent mistakes within healthcare - Balancing life and professional obligations - Writing and updating your Curriculum Vitae - Resources for determining your school of choice - Suggestions for dual degree programs - How to establish a specialty, if you so choose - Brief overview of sciences required for entry into pharmacy school - Differences between residencies and fellowships and when each may be applicable o Application and information for success in each - Establishing connections within the field - Conducting yourself professionally Read "Pharmacist 101" today and all the best in your journey towards becoming a pharmacist! About the Expert Ann Klemz, PharmD, is a hospital pharmacist from Minnesota. She graduated from the University of Minnesota, Duluth campus in 2012. She has worked in the field of pharmacy as a technician, intern, and pharmacist for over twenty years. She's worked in retail, hospital, minor clinical roles, home infusion, and hospice. Her perspective is inclusive and unique. Her strengths include Harmony, Adaptability, Developer, Empathy, and Positivity, with a punch of Activator and Intellection for good measure. When she's not at work, she can be found drinking coffee, cross-stitching, and mitigating the craziness of her three-child household with her loving partner, Tim. HowExpert.com publishes quick 'how to' guides in all topics from A to Z by everyday experts.
Fibromyalgia
FIBROMYALGIA This book aims to serve as a guide to Fibromyalgia, educating you on the condition and helping you to better understand how it can be treated. Being considered a chronic disease, there is no current cure for Fibromyalgia. However, there are many ways to improve the condition, and reduce associated symptoms. Throughout this book, you will learn about how Fibromyalgia is diagnosed, what the different symptoms are, how it is currently treated with Western medicine, and how you can treat it with some alternative therapies and dietary changes! Through implementing the strategies and suggestions given in this book, you will have a much greater chance of improving your fibromyalgia, and finding some relief! Here Is A Preview Of What You'll Learn About Inside... What Is Fibromyalgia How Fibromyalgia Is Diagnosed Causes And Symptoms Of Fibromyalgia Coping Strategies Using Diet To Improve Fibromyalgia Treating Fibromyalgia With Western Medicine Best Exercises For Fibromyalgia Using Essential Oils To Improve Fibromyalgia Symptoms Much, Much More!
Pharmakogenetik. Das individuelle Genom bei der MedikamentenvergabeWelche Chancen ergeben
Einsendeaufgabe aus dem Jahr 2018 im Fachbereich Medizin - Pharmakologie, Arzneimittelwesen, Friedrich-Alexander-Universit瓣t Erlangen-N羹rnberg, Sprache: Deutsch, Abstract: Die Pharmakogenetik untersucht den Einfluss des Erbguts auf den Stoffwechsel und somit die Wirksamkeit von Medikamenten. Dies erlaubt eine personalisierte Dosierung der Arzneimittel zur Vermeidung von Unter- oder ?berdosierungen. Der Zusammenhang der genetischen Ausstattung von Patienten mit der Wirksamkeit einiger Medikamente ist dabei schon l瓣nger bekannt. Aktuelle Forschung hat die Aufschl羹sselung der genetischen Variabilit瓣t der Arzneimittelwirksamkeit auf breiter Basis zum Inhalt. Erkenntnisse flie?en dabei in die Medikamentenentwicklung und die Individualisierung der Pharmakotherapie ein. ?bersicht zur Entwicklung der Pharmakotherapie. Welche Chancen ergeben sich durch die pharmakogenetische Forschung? Was sind m繹gliche Risiken? Muss zuk羹nftig das individuelle Genom entschl羹sselt werden, bevor Medikamente verordnet werden k繹nnen?
Apis Mellifica
Apis Mellifica: Or, The Poison Of The Honey-Bee, Considered As A Therapeutic Agent This book is a result of an effort made by us towards making a contribution to the preservation and repair of original classic literature. In an attempt to preserve, improve and recreate the original content, we have worked towards: 1. Type-setting & Reformatting: The complete work has been re-designed via professional layout, formatting and type-setting tools to re-create the same edition with rich typography, graphics, high quality images, and table elements, giving our readers the feel of holding a 'fresh and newly' reprinted and/or revised edition, as opposed to other scanned & printed (Optical Character Recognition - OCR) reproductions. 2. Correction of imperfections: As the work was re-created from the scratch, therefore, it was vetted to rectify certain conventional norms with regard to typographical mistakes, hyphenations, punctuations, blurred images, missing content/pages, and/or other related subject matters, upon our consideration. Every attempt was made to rectify the imperfections related to omitted constructs in the original edition via other references. However, a few of such imperfections which could not be rectified due to intentional\unintentional omission of content in the original edition, were inherited and preserved from the original work to maintain the authenticity and construct, relevant to the work. We believe that this work holds historical, cultural and/or intellectual importance in the literary works community, therefore despite the oddities, we accounted the work for print as a part of our continuing effort towards preservation of literary work and our contribution towards the development of the society as a whole, driven by our beliefs. We are grateful to our readers for putting their faith in us and accepting our imperfections with regard to preservation of the historical content. HAPPY READING!
I profumi che curano corpo, mente e spirito
"Questa opera rappresenta un excursus Storico-Religioso-Filosofico-Mitologico-Antropologico e Medico-Scientifico, al fine di portare per mano il lettore a metabolizzare i principi secondo cui l'Aromaterapia al pari di tutte le conoscenze sulla Medicina Naturale sono stati parte integrante delle terapie di ogni tempo e possono esserlo anche nei tempi moderni e attuali Il lavoro dell'autrice ha destato il mio interesse e gradimento perch矇 rappresenta un documento non solo rivolto ad una classe specifica di Professionisti del settore Medico-Scientifico, ma per la semplicit? con cui 癡 scritto risulta facilmente comprensibile a tutti coloro che desiderano estendere le proprie conoscenze riguardo gli oli essenziali ed il loro utilizzo nella quotidianit? e nella prevenzione primaria". Dr. Maurizio Maresca
Optimal Men’s Health
Optimal Men's Health is a comprehensive yet easy-to-understand guide to everything men (and the women who care about them) need to know about health. Taking an integrative approach, Dr. Myles Spar shows you how to feel young and powerful at any age while minimizing the risk of disease, showing that prevention is just as important as treatment. Using real patient experience, Dr. Spar explains the usefulness of advanced testing; the usefulness of integrative medicine approaches such as mindfulness, an anti-inflammatory diet, how to optimize sleep, and the use of supplements for all of the conditions; and uses various complementary treatments and therapies that can be useful in preventing and treating diseases through acupuncture, yoga, exercise, and more. Dr. Spar provides you with lists of questions to ask your healthcare professional, sidebars of key information, checklists and action plans, lists of resources and suggested further reading for you to take your health journey into your own hands.
DMSO - Um Manual
DMSO n瓊o 矇 permut獺vel e apresenta impressionante gama de efeitos harm繫nicos. Constantemente pesquisas m矇dicas e farmac礙uticas evidenciam que DMSO oferece o maior n繳mero e espectro de efeitos jamais comprovados para uma 繳nica subst璽ncia. Ao longo de mais de sessenta anos foram publicados mais de quarenta mil artigos cient穩ficos a seu respeito. Geralmente s瓊o de completo desconhecimento do p繳blico leigo - ou foram mesmo retidos intencionalmente. Agora todos os interessados t礙m ? sua disposi癟瓊o um livro de primeira qualidade sobre esse rem矇dio universal e sua aplica癟瓊o pr獺tica, de autoria de Dr. Hartmut Fischer, cientista em ci礙ncias naturais e naturopata, que investigou esse fascinante l穩quido e dele faz uso bem-sucedido no consult籀rio e em seu meio familiar. Agora esse livro compreende todo seu conhecimento a respeito. Aprox. 300 p獺ginas, com 44 imagens. Atualmente DMSO experimenta um revival enquanto sust璽ncia terap礙utica de livre acesso, ap籀s anos de oculta癟瓊o por peritos e m矇dicos alternativos. Sempre bem tolerado, entrementes obteve fama como recurso de r獺pido efeito no tratamento de enfermidades traum獺ticas e de inflama癟繭es agudas. Tem efeito anti-inflamat籀rio e analg矇sico imediato, acarreta r獺pida reabsor癟瓊o de incha癟os ou hemorragias cut璽neas, e favorece a cicatriza癟瓊o. Por isso mesmo 矇 muito usada quando de les繭es desportivas, s穩ndromes dos ombros, enfermidades reum獺ticas e degenerativas em juntas (incluindo altera癟繭es nos discos intervertebrais), e neuralgias. Mas DMSO faz muito mais, o que n瓊o descobriram apenas cirurgi繭es pl獺sticos, m矇dicos cir繳rgicos, veterin獺rios e do desporto, sen瓊o tamb矇m in繳meras pessoas ? procura de curas alternativas para seus males cr繫nicos. No caso do DMSO trata-se, pois, de um componente extremamente vers獺til para a independ礙ncia terap礙utica e de um bocado de independ礙ncia m矇dica dos vastos efeitos colaterais da medicina padr瓊o. Muitos dos interessados, contudo, desconheciam o manejo seguro dessa subst璽ncia e as possibilidades de seu emprego. Em s穩ntese: faltava um manual concreto para o emprego pr獺tico de DMSO. Com este livro apresenta-se, portanto, uma obra cl獺ssica, voltada primeiramente a sua aplica癟瓊o, tanto para usu獺rios quanto m矇dicos, naturopatas e demais terapeutas. Por isso mesmo a presente obra pretende antes transmitir o emprego pr獺tico e manejo seguro de DMSO. Para al矇m disso, o leitor pode muito bem aproveitar esse texto para uma leitura prazerosa, pois v獺rios trechos transcendem o estrito campo do DMSO, fornecendo-lhe aleatoriamente avultados conhecimentos Cr穩ticas.Uma obra-mestra cuja virtude consiste na explana癟瓊o simples de processos complexos, tornados intelig穩veis, permitindo a muitos um proveito de conhecimentos de muitos anos. Dra da medicina Antje Oswald
Designing Hydrogels for Controlled Drug Delivery
The aim of this book is to provide an analysis of the main characteristics and applications of hydrogels. Hydrogels are frequently used for manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery systems, and wound dressings. These materials are useful in everyday life, so publicizing them in both academic and pharmaceutical fields is essential.
Dancing to the Light
"Dancing is Life" "This is a quote that is a direct parallel to life.It rejuvenates us, keeps us sound, keeps us creating, instead of dying."Quote Tony Dovolani of "Dancing with the Stars" World Rhythm Champion CELEBRATING LIVING 20 YEARS DIAGNOSED WITH ALZHEIMER'S DISEASE CELEBRATING A DECADE OF DANCE FOR DEMENTIA Diagnosed in 1999 with Alzheimer's Disease at age 53, every day I fight a battle to still be me. A Battle wages within a silent predator the Thief of my Mind, Memory, and Me. Traveling through the Valley of the Shadow of Death When you hear you are dying, you feel yourself disappearing just fading away "There is a Time to Dance!" "God Changed My Mourning into Dancing!" Ballroom Dance the Missing Link in Rehabilitation of my Mind and Body Creating a Voice for the Message of HOPE for the Disease of Alzheimer's . . . sharing my Story and my Interpretative Dance. HAZEL MINNICK "REMEMBER ME!" I am a Voice that needs to be heard A Mind that needs to be understood A Disease that needs Explanation A Cure! I Am "The Unlikely Dancer"I Am "Dancing to Live!"I Am "Dancing to the Light!" I invite you to read my book series Learn how I tamed the monster living within my Brain to the tune of music. From Walker/Wheelchair to Waltzing "I Am Dancing to Live!" "LIVING IN MY SHADOW My Journey with Alzheimer's" promoting early Diagnosis, Meds to Reverse the Symptoms, and Ballroom Dance the missing link to Rejuvenate the Mind and Body. Then continue to follow my journey as "The Unlikely Dancer" and join me as I take the final steps of my journey with Alzheimer's Disease in "Dancing to the Light." My future writings will be memoirs to my Children and Grandchildren leading them to follow the Path of Light to Heaven, also featuring Alzheimer's "funnies" experienced together. Blessings Always Hazel Minnick URElderDancing Princess xoxox
Seaweeds Secondary Metabolites
Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer's disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
Field Hospitals
Field hospitals are deployed in a wide range of scenarios including natural disasters, epidemic outbreaks, armed conflicts and refugee crises. Operation in these conditions requires adaptation to disaster medicine principles and operation in an austere environment and unfamiliar cultural milieu, whilst maintaining acceptable standards of care. For many of those involved it may be their first encounter. This book, which is the first to address the preparation and operation of field hospitals, brings together the experience of world leaders in the field. Coming from a wide variety of organizations and backgrounds, all have extensive experience in field hospital deployment in multiple scenarios. The text - containing both background information and practical guidelines - will serve all those involved in field hospital deployment, including policy makers and planners, physicians and nurses, paramedical professionals and logisticians. It will help them deliver optimal care to people around the globe in difficult times of need.
Transmucosal Absorption Enhancers in the Drug Delivery Field
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled "Transmucosal Absorption Enhancers in the Drug Delivery Field" aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.
Cell－Free Nucleic Acids
The deficits of mammography and the potential of noninvasive diagnostic testing using circulating miRNA profiles are presented in our first review article. Exosomes are important in the transfer of genetic information. The current knowledge on exosome-associated DNAs and on vesicle-associated DNAs and their role in pregnancy-related complications is presented in the next article. The major obstacle is the lack of a standardized technique for the isolation and measurement of exosomes. One review has summarized the latest results on cell-free nucleic acids in inflammatory bowel disease (IBD). Despite the extensive research, the etiology and exact pathogenesis are still unclear, although similarity to the cell-free ribonucleic acids (cfRNAs) observed in other autoimmune diseases seems to be relevant in IBD. Liquid biopsy is a useful tool for the differentiation of leiomyomas and sarcomas in the corpus uteri. One manuscript has collected the most important knowledge of mesenchymal uterine tumors and shows the benefits of noninvasive sampling. Microchimerism has also recently become a hot topic. It is discussed in the context of various forms of transplantation and transplantation-related advanced therapies, the available cell-free nucleic acid (cfNA) markers, and the detection platforms that have been introduced. Ovarian cancer is one of the leading serious malignancies among women, with a high incidence of mortality; the introduction of new noninvasive diagnostic markers could help in its early detection and treatment monitoring. Epigenetic regulation is very important during the development of diseases and drug resistance. Methylation changes are important signs during ovarian cancer development, and it seems that the CDH1 gene is a potential candidate for being a noninvasive biomarker in the diagnosis of ovarian cancer. Preeclampsia is a mysterious disease--despite intensive research, the exact details of its development are unknown. It seems that cell-free nucleic acids could serve as biomarkers for the early detection of this disease. Three research papers deal with the prenatal application of cfDNA. Copy number variants (CNVs) are important subjects for the study of human genome variations, as CNVs can contribute to population diversity and human genetic diseases. These are useful in NIPT as a source of population specific data. The reliability of NIPT depends on the accurate estimation of fetal fraction. Improvement in the success rate of in vitro fertilization (IVF) and embryo transfer (ET) is an important goal. The measurement of embryo-specific small noncoding RNAs in culture media could improve the efficiency of ET.
Ethiopian Reproductive, Maternal, Newborn and Child Health (RMNCH) Medicines Formulary
Document from the year 2016 in the subject Medicine - Pharmacology, language: English, abstract: To provide basic information on the management and appropriate prescribing, dispensing and use of RMNCH medicines will familiarize with the terminologies used in drug management, the medicines used, including their generic names, uses, doses, precautions, side effects, storage and handling, advising/counselling patients. It thereby addresses the scope of knowledge which will fill those information gaps on how best use RMNCH medicines by healthcare providers and clients. The formulary apart from being used as desk reference by Health care providers can also be used as a resource material during the basic training of Health care providers who specifically deal with RMNCH services.
